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1.
BMC Oral Health ; 24(1): 106, 2024 Jan 18.
Article in English | MEDLINE | ID: mdl-38238723

ABSTRACT

OBJECTIVE: This study aims to discuss the characteristics and treatment methods of malignant tumors in the parotid region, as well as the therapeutic effects of immediate free flap reconstruction of soft tissue for postoperative defects. MATERIALS AND METHODS: A retrospective review was conducted on 11 cases of soft tissue flap reconstruction for postoperative defects following the resection of malignant tumors in the parotid region. Statistical analysis was performed based on clinical data. RESULTS: Among the 11 cases of malignant tumors in the parotid region, there were 2 cases of secretory carcinoma (SC) of the salivary gland, 2 cases of squamous cell carcinoma (SCC), 2 cases of carcinosarcoma, 1 case of mucoepidermoid carcinoma (MEC), 1 case of epithelial-myoepithelial carcinoma (EMC), 1 case of salivary duct carcinoma (SDC), 1 case of basal cell carcinoma (BCC), and 1 case of osteosarcoma. Among these cases, 4 were initial diagnoses and 7 were recurrent tumors. The defect repairs involved: 8 cases with anterolateral thigh free flap (ALTF), 2 cases with pectoralis major muscle flaps, and 1 case with forearm flap. The size of the flaps ranged from approximately 1 cm × 3 cm to 7 cm × 15 cm. The recipient vessels included: 4 cases with the facial artery, 4 cases with the superior thyroid artery, and 1 case with the external carotid artery. The ratio of recipient vein anastomosis was: 57% for branches of the internal jugular vein, 29% for the facial vein, and 14% for the external jugular vein. Among the 8 cases that underwent neck lymph node dissection, one case showed lymph node metastasis on pathological examination. In the initial diagnosis cases, 2 cases received postoperative radiotherapy, and 1 case received 125I seed implantation therapeutic treatment after experiencing two recurrences. Postoperative follow-up revealed that 2 cases underwent reoperation due to local tumor recurrence, and there were 2 cases lost to follow-up. The survival outcomes after treatment included: one case of distant metastasis and one case of death from non-cancerous diseases. CONCLUSION: Immediate soft tissue flap reconstruction is an important and valuable option to address postoperative defects in patients afflicted with malignant tumors in the parotid region.


Subject(s)
Carcinoma, Squamous Cell , Skin Transplantation , Humans , Parotid Region/pathology , Parotid Region/surgery , Neoplasm Recurrence, Local/surgery , Carcinoma, Squamous Cell/surgery , Carcinoma, Squamous Cell/pathology , Algorithms
3.
Arq. bras. med. vet. zootec. (Online) ; 72(6): 2245-2251, Nov.-Dec. 2020. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1142291

ABSTRACT

The present report aimed to describe the main characteristics of the parotid salivary mucocele in an adult male rabbit, which presented with a painless fluctuating mass with fluid content. Owing to the need for repeated fluid drainage, surgical excision was the chosen mode of treatment. Preoperative evaluation included radiography and blood analysis. The patient underwent surgical excision of the affected gland. Inhalation anesthesia was maintained by means of isoflurane and the cardio-respiratory parameters were monitored throughout the surgery. A bipolar electrocautery was used to assist in the incision and polyglactin 910 and nylon were the suture materials used in the wound closure technique. Post-operative medications included analgesics, anti-inflammatory agents and antibiotics. Histopathology of the excised glandular tissue revealed a mixed inflammatory infiltrate, fibroblasts, hemorrhage and hyperemia. The observations in this case suggest that surgical excision of the affected gland is the treatment of choice for the management of mucocele in companion rabbits, which has already been identified for other animals. Periodic acid-reactive Schiff staining confirmed the diagnosis of salivary mucocele. The complementary investigations helped to rule out the differential diagnosis and indicated a favorable prognosis, in view of the fact that the case was successfully resolved without complications or recurrence.(AU)


O presente relato teve como objetivo descrever as principais características da mucocele salivar parotídea em um coelho macho adulto, que apresentou uma massa flutuante indolor e com um conteúdo líquido em seu interior. Devido à necessidade de repetidas punções deste fluido, optou-se pela excisão cirúrgica como forma de tratamento. A avaliação pré-operatória incluiu radiografias e análises sanguíneas. O paciente foi submetido ao tratamento cirúrgico com excisão da glândula afetada. A anestesia inalatória foi mantida com isoflurano e os parâmetros cardio-respiratórios foram monitorados durante a cirurgia. Um eletrocautério bipolar foi utilizado para auxiliar na incisão e os fios poliglactina 910 e nylon foram utilizados na técnica de sutura. As medicações pós-operatórias incluíram agentes analgésicos, anti-inflamatórios e antibióticos. A histopatologia do tecido glandular removido revelou infiltrado inflamatório misto, fibroblastos, hemorragia e hiperemia. As observações neste caso sugerem que a remoção cirúrgica da glândula afetada seja o tratamento de escolha no manejo da mucocele em coelhos de companhia, o que já vem sendo identificado para outros animais. A coloração do ácido periódico reativo de Schiff confirmou o diagnóstico da mucocele salivar. Os exames complementares ajudaram a excluir as doenças que fazem parte do diagnóstico diferencial e indicaram um prognóstico favorável, tendo em vista o fato que este caso foi resolvido com sucesso, sem complicações ou recorrência.(AU)


Subject(s)
Animals , Male , Rabbits , Salivary Glands/surgery , Parotid Region/surgery , Mucocele/veterinary , Periodic Acid-Schiff Reaction/veterinary
4.
Otolaryngol Pol ; 74(5): 1-5, 2020 Jun 01.
Article in English | MEDLINE | ID: mdl-33028736

ABSTRACT

<b>Objective:</b> The feasibility, surgical outcomes and possible risks and complications encountered during a facelift procedure for patients with parapharyngeal space (PPS) tumor were analyzed. <br><b>Method:</b> This retrospective analysis examined 10 patients who underwent surgery for PPS tumor using a facelift incision at our institutes between April 2015 and August 2019. <br><b>Results:</b> This study included four retro-styloid (benign nerve sheath tumor) and six pre-styloid tumors (pleomorphic adenoma). Mean tumor dimensions were 4.1 x 4.2 x 3.8 cm respectively. None of the patients needed conversion to conventional open resection. Transient sensory changes in the auricle occurred in 30% of the patients; however, all recovered within four months. In all the patients, postoperative scars were fully concealed by the auricle and hair. No recurrences were detected during a mean follow-up period of 16.6 months. <br><b>Conclusion: </b>The facelift procedure provides adequate visualization, workspace and excellent cosmetic results in properly selected cases.


Subject(s)
Otorhinolaryngologic Surgical Procedures/methods , Parotid Region/surgery , Pharyngeal Neoplasms/surgery , Rhytidoplasty/methods , Adult , Female , Humans , Male , Middle Aged , Retrospective Studies
5.
Rev. esp. cir. oral maxilofac ; 42(1): 4-11, ene.-mar. 2020. ilus, tab
Article in Spanish | IBECS | ID: ibc-195292

ABSTRACT

INTRODUCCIÓN: La cirugía parotídea es una técnica muy habitual y presenta múltiples tipos de abordajes y métodos de reconstrucción. Las distintas opciones de reconstrucción primarias empleadas son el colgajo del sistema músculo aponeurótico superficial (SMAS), la rotación del músculo esternocleidomastoideo (ECM), injertos libres/microvascularizados o la utilización de biomateriales tipo Alloderm, entre otros. Se presenta nuestra experiencia en la utilización de injerto de grasa libre abdominal periumbilical para la reconstrucción primaria del defecto parotídeo. MATERIAL Y MÉTODOS: Se realiza un estudio observacional de las reconstrucciones con injerto de tejido graso libre abdominal en pacientes que precisaron la realización de una parotidectomía (superficial, total o radical) debida a una neoplasia parotídea primaria o a una recidiva tumoral. Los pacientes fueron intervenidos por el mismo cirujano entre mayo de 2013 y enero de 2019. El estudio analiza aspectos epidemiológicos y clínicos de los pacientes, los abordajes y el tiempo quirúrgico, la estancia hospitalaria, las complicaciones postquirúrgicas, las secuelas, el seguimiento clínico y el resultado estético de los pacientes. RESULTADOS: Un total de 22 pacientes fueron intervenidos con utilización de injertos de grasa abdominal tras una parotidectomía superficial conservadora, total o radical. Fueron trece hombres y nueve mujeres de edades entre 13 y 79 años (46 años de media), con el diagnóstico inicial realizado mediante punción aspiración por aguja fina (PAAF) y tomografía computerizada (TC) o resonancia magnética (RM). El resultado estético en todos los pacientes fue muy bueno o excelente. No secuelas a largo plazo ni síndrome de Frey. No complicaciones de interés, salvo leves hematomas y seromas postquirúrgicos. CONCLUSIÓN: Se presenta una técnica muy sencilla y con muy pocas complicaciones para la reconstrucción primaria de defectos postparotidectomía a través de mínimas incisiones con unos excelentes resultados estéticos


INTRODUCTION: Parotid surgery is a common technique with multiple approaches and reconstruction options. Primary reconstruction options are the superficial musculoaponeurotic system (SMAS) flap, the sternocleidomastoid muscle flap, free or microvascular grafts and biomaterials (Alloderm), among others. We present our experience in periumbilical abdominal free fat graft for primary reconstruction of the parotid defect. MATERIAL AND METHODS: A observational study was performed in patients requiring a parotidectomy (superficial, total or radical) due to a primary parotid neoplasm or tumor recurrence. In all cases were used a free abdominal fat graft. The patients were operated by the same surgeon between May 2013 and January 2019. The study analyzes epidemiological and clinical aspects, approach, surgical time, hospital stay, post-surgical complications, sequelae, clinical follow-up and aesthetic results. RESULTS: A total of 22 patients were incluyed after a conservative, total or radical superficial parotidectomy. Thirteen men and nine women aged between 13 and 79 years (46 years on average), with the initial diagnosis made by fine water aspiration puncture (FNA) and Computerized Tomography (CT) or Magnetic Resonance Imaging (MRI). Aesthetic result in all patients was excellent or very good. No long-term sequelae or syndromes Frey. No complications interest except minor postsurgical hematomas and seroma. CONCLUSIONS: A very simple technique with few complications is presented for the primary reconstruction of postparotidectomy defects with excellent aesthetic results


Subject(s)
Humans , Male , Female , Adolescent , Young Adult , Adult , Middle Aged , Aged , Parotid Region/surgery , Parotid Neoplasms/surgery , Plastic Surgery Procedures/methods , Free Tissue Flaps , Abdominal Fat/transplantation , Treatment Outcome , Sweating, Gustatory/prevention & control
6.
Eur Arch Otorhinolaryngol ; 276(11): 3185-3193, 2019 Nov.
Article in English | MEDLINE | ID: mdl-31338575

ABSTRACT

PURPOSE: Periauricular sensory deficit occurs frequently after parotidectomy even in cases with preservation of the greater auricular nerve (GAN). This study was performed to evaluate the effects of antiadhesive agent in functional recovery of the GAN after parotidectomy. METHODS: Ninety-eight patients undergoing partial parotidectomy for benign parotid tumors were prospectively enrolled in this multicenter, double-blind randomized controlled study and randomly assigned to either the study or control group. Antiadhesive agent was applied in the study group. The results of sensory tests (tactile, heat, and cold sensitivity) and a questionnaire on quality of life (QoL) were acquired at postoperative 1, 8, and 24 weeks after surgery. Clinical parameters, and the results of the sensory tests and the questionnaire, were compared between the two groups. RESULTS: A total of 80 patients were finally enrolled. On sensory evaluation, tactile sensation and warm sensation in the ear lobule, and warm sensation in the mastoid area, showed significant improvement at 24 weeks postoperatively in the study group. There were no significant differences between the two groups on any questions in the QoL questionnaire, at any follow-up time point. CONCLUSIONS: Antiadhesive agents have some positive effects on functional recovery of the GAN after parotidectomy. Therefore, applying antiadhesive agents after parotidectomy can reduce discomfort in patients.


Subject(s)
Agnosia , Cervical Plexus/injuries , Dissection , Parotid Gland/surgery , Parotid Neoplasms/surgery , Peripheral Nerve Injuries , Tissue Adhesions , Agnosia/diagnosis , Agnosia/etiology , Agnosia/therapy , Dissection/adverse effects , Dissection/methods , Double-Blind Method , Female , Humans , Male , Middle Aged , Parotid Gland/pathology , Parotid Neoplasms/pathology , Parotid Region/innervation , Parotid Region/surgery , Peripheral Nerve Injuries/diagnosis , Peripheral Nerve Injuries/etiology , Peripheral Nerve Injuries/therapy , Recovery of Function/physiology , Tissue Adhesions/etiology , Tissue Adhesions/prevention & control , Treatment Outcome
8.
Otolaryngol Pol ; 72(4): 9-16, 2018 May 16.
Article in English | MEDLINE | ID: mdl-30190441

ABSTRACT

INTRODUCTION: Parapharyngeal space (PPS) is the anatomical area lateral to the upper pharynx and clinically important due to PPS tumors. They account for less than 1% of head and neck neoplasms. Both benign and malignant neoplasms may arise there and typical for this localization is diversity of histological origin. Complete surgical excision is still the basis of treatment. AIM OF THE STUDY: Evaluation of the results of surgical treatment of PPS tumors in the Department of Otolaryngology at the Medical University over the period 2015-2017. MATERIAL AND METHODS: A retrospective analysis of medical records including complaints, physical examination, results of imaging studies, surgical approach, postoperative complication and histopathological results in 22 patients with a diagnosis of a PPS tumors. RESULTS: The most frequent complaints reported by the patients were: discomfort in the throat, dysphagia, hearing disorders and a palpable tumor on the neck. Asymptomatic course of the disease was demonstrated in 4 cases. All patients were treated surgically: 2 with transoral approach, 9 with transparotid-transcervical approach, 11 with transcervical approach. In most cases the tumor was removed radically. In 2 patients intracapsular tumor resection was performed. Based on histopathological examination the benign lesions dominated (18/22). In 4 cases malignant neoplasms were diagnosed: carcinoma ex pleomorphic adenoma, adenoid cystic carcinoma and two cases of squamous cell carcinoma. The most common origin of PPS tumors was deep lobe of parotid gland and for this group 11 patients had diagnosis of pleomorphic adenoma. Other diagnosis included: paraganglioma, neurofibroma, hemangioma, lymphangioma and rhabdomyoma. Postoperative complications occurred in 9 patients and presented as hoarseness and dysphagia due to paresis of the lower group of cranial nerves (IX, X, XII). Significant intraoperative bleeding during surgery occurred in 2 cases and ligation of the external carotid artery was necessary. CONCLUSION: Due to the anatomical topography of PPS and its content with the essential vessels and the lower group of cranial nerves, the surgical treatment of pathology of this area is still a challenge for head and neck surgeons. The decrease of voice quality and impaired speech and swallowing should always be considered as complications post the surgical resection in PPS.


Subject(s)
Parotid Region/surgery , Pharyngeal Neoplasms/surgery , Postoperative Complications/etiology , Adult , Aged , Female , Humans , Male , Middle Aged , Neck/surgery , Otorhinolaryngologic Surgical Procedures , Pharyngeal Neoplasms/pathology , Pharynx/surgery , Retrospective Studies , Treatment Outcome
9.
Ear Nose Throat J ; 95(12): E1-E6, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27929599

ABSTRACT

We conducted a retrospective study to analyze the role of the cervical and lateral skull base approaches in the surgical excision of parapharyngeal space (PPS) tumors. Our study population was made up of 34 patients-15 males and 19 females, aged 13 to 73 years (mean: 50.6)-who had presented to us with a PPS tumor during a 9-year period. The 34 cases included 23 benign tumors and 11 malignancies. The 23 benign tumors consisted of 11 pleomorphic adenomas, 5 schwannomas, 2 paragangliomas, 2 Warthin tumors, 1 oncocytoma, 1 hamartoma, and 1 osteochondroma. The 11 malignancies included 3 cases of recurrent nasopharyngeal carcinoma, 2 cases of mucoepidermoid carcinomas, and 1 case each of carcinoma ex pleomorphic adenoma, liposarcoma, lymph node metastasis from nasopharyngeal carcinoma, lymph node metastasis from follicular thyroid carcinoma, rhabdomyosarcoma, and cranial nerve (CN) X neurofibrosarcoma. Among the benign tumors, 14 were removed via the transparotid approach, 3 via the transcervical approach, 3 via the transcervical-transparotid approach, 2 via the petro-occipital-trans-sigmoid approach, and 1 via the Fisch type A infratemporal fossa approach. During postoperative follow-up, 5 of the 23 patients with a benign tumor exhibited facial nerve paresis, 2 developed CN IX to XII palsy, and 1 each developed Frey syndrome and CN X palsy. In the malignant tumor group, 4 of the 11 patients were treated via the transcervical-transparotid approach, 3 via the Fisch type C infratemporal fossa approach, 3 via the transcervical-transmandibular approach, and 1 via the transcervical-lateral petrosectomy approach. The neural deficits observed during the postoperative period were more extensive among the patients with a malignant tumor. We conclude that the transparotid and transcervical approaches were adequate for excising most benign tumors. For malignant tumors, large tumors, and tumors with skull base involvement and transcranial extension, the transparotid-transcervical, transcervical-transmandibular, infratemporal fossa, and petro-occipital-trans-sigmoid approaches were necessary.


Subject(s)
Otorhinolaryngologic Surgical Procedures/methods , Pharyngeal Neoplasms/surgery , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Neck/surgery , Parotid Region/surgery , Pharyngeal Neoplasms/pathology , Pharynx/pathology , Pharynx/surgery , Postoperative Complications/etiology , Retrospective Studies , Skull Base/surgery , Treatment Outcome , Young Adult
10.
Laryngoscope ; 126(7): 1581-4, 2016 07.
Article in English | MEDLINE | ID: mdl-26915301

ABSTRACT

OBJECTIVES/HYPOTHESIS: Evaluate the difference of the incidence in clinical Frey syndrome in studies comparing classical parotidectomy and parotidectomy with superficial musculoaponeurotic system (SMAS) flap elevation and suturing through meta-analysis methodology. STUDY DESIGN: Meta-analysis of controlled studies with and without SMAS flap. METHODS: Database search with the following key word combination: "Frey syndrome" and "SMAS." INCLUSION CRITERIA: parotidectomy, SMAS flap and control groups, minimal follow-up of 1 year. The outcome was the presence of clinical Frey syndrome. RESULTS: Eleven studies, mostly retrospective and not randomized. According to the fixed-effect model, SMAS technique is associated with a decrease of clinical Frey syndrome with an odds ratio (OR) of 0.42 (confidence interval [CI] 0.32-0.56). With the random-effect model, the difference remains significant (P = 0.006) with an OR of 0.25 (CI 0.09-0.66). The heterogeneity index I(2) is very high (85%). CONCLUSION: The use of SMAS flap and suturing is associated with a decreased incidence of Frey syndrome. Laryngoscope, 126:1581-1584, 2016.


Subject(s)
Plastic Surgery Procedures/methods , Postoperative Complications/prevention & control , Superficial Musculoaponeurotic System/transplantation , Surgical Flaps/surgery , Sweating, Gustatory/prevention & control , Clinical Studies as Topic , Humans , Parotid Diseases/surgery , Parotid Region/surgery , Postoperative Complications/etiology , Sweating, Gustatory/etiology
11.
Eur Arch Otorhinolaryngol ; 273(10): 3269-75, 2016 Oct.
Article in English | MEDLINE | ID: mdl-26749559

ABSTRACT

The aim of this study is to show differences between a modified facelift incision (MFI) for partial parotidectomy versus a bayonet-shaped incision (BSI). 24 patients presenting with a parotid tumor were surgically treated with a partial parotidectomy using a MFI. We generated a "matched pair control group" regarding age, tumor size and gender, who received a BSI. A questionnaire was sent to all patients and relevant data reviewed. The cosmetic satisfaction on a VAS with a MFI was 9.74 (±0.47) compared to BSI with 7.63 (±2.44, p = 0.004). The scoring in the two subgroups "visible scar" and "people noticed my surgery" was significantly better in the MFI group The postoperative skin numbness, skin depression, facial nerve function postoperatively showed no statistical differences. The MFI for parotid tumors has a better outcome than the BSI regarding cosmetic satisfaction and visible scarring.


Subject(s)
Adenoma , Cicatrix , Parotid Neoplasms , Postoperative Complications , Rhytidoplasty , Adenoma/pathology , Adenoma/surgery , Adult , Cicatrix/etiology , Cicatrix/prevention & control , Cicatrix/psychology , Female , Humans , Male , Middle Aged , Neoplasm Staging , Outcome and Process Assessment, Health Care , Parotid Gland/pathology , Parotid Gland/surgery , Parotid Neoplasms/pathology , Parotid Neoplasms/surgery , Parotid Region/surgery , Patient Satisfaction , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Postoperative Complications/psychology , Research Design , Rhytidoplasty/adverse effects , Rhytidoplasty/methods , Visual Analog Scale
12.
J Craniofac Surg ; 26(6): 1972-4, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26192031

ABSTRACT

OBJECTIVE: The aim of this study is to present our experience with a modification of the Blair approach to the parotid area, by means of a modified endaural component, which provides both excellent exposure and optimal functional and esthetic results, mainly over the preauricular area. PATIENTS AND METHODS: A retrospective case series study was performed. It included surgical cases of patients who were operated on the parotid region in which the mentioned approach was indicated. The information was collected from the database available at the Universidad El Bosque Oral and Maxillofacial Surgery Department in Bogota, Colombia from 2008 to 2013. RESULTS: The sample consisted of 12 patients, with ages ranging from 23 to 56 years and a mean age of 38 years. A total of 8 patients were women and 4 patients were men. Parotid pathologies included salivary gland tumor (10 patients) and cranial base tumor (2 patients). Procedures executed were: superficial lobe and total parotidectomy resection, pharynx extended and cranial base tumor resections. CONCLUSIONS: This investigation presents our experience with a modified approach to the parotid region. This approach gives an extended and safe exposure to the region with excellent cosmetic outcomes.


Subject(s)
Parotid Region/surgery , Adult , Dissection/instrumentation , Dissection/methods , Esthetics , Female , Follow-Up Studies , Humans , Male , Middle Aged , Parotid Gland/surgery , Parotid Neoplasms/surgery , Pharynx/surgery , Retrospective Studies , Skull Base Neoplasms/surgery , Treatment Outcome , Young Adult
13.
J Craniofac Surg ; 26(3): 782-4, 2015 May.
Article in English | MEDLINE | ID: mdl-25950527

ABSTRACT

Hyaluronic acid (HA) fillers have been the choice material for soft tissue augmentation in the last decade. Although they are considered safe, there could be adverse reactions in the subsequent months or years to the treatment. However, these reactions have hardly ever been reported in the literature. This article considers 2 cases of delayed adverse reactions related to HA dermal filler for soft tissue augmentation with oral manifestation. It should be, before all, emphasized that HA filler is a safe and well-recognized treatment for soft tissue augmentation, despite the fact that delayed adverse effects may later occur after treatment, and clinicians should be aware of it when establishing a definitive oral diagnosis.


Subject(s)
Biocompatible Materials/adverse effects , Dermal Fillers/adverse effects , Hyaluronic Acid/adverse effects , Lip/surgery , Surgery, Plastic/adverse effects , Surgery, Plastic/methods , Aged, 80 and over , Biocompatible Materials/administration & dosage , Dermal Fillers/administration & dosage , Female , Foreign Bodies/surgery , Humans , Hyaluronic Acid/administration & dosage , Hyaluronic Acid/analogs & derivatives , Hyaluronoglucosaminidase/administration & dosage , Injections, Subcutaneous , Parotid Region/surgery , Postoperative Complications/surgery , Reoperation
14.
Asian Pac J Cancer Prev ; 15(14): 5701-7, 2014.
Article in English | MEDLINE | ID: mdl-25081689

ABSTRACT

BACKGROUND: Salivary gland tumours, which account for approximately 3% of head-neck cancers, are a heterogeneous group and thus it is difficult to identify their epidemiological characteristics. The aim of this study is to determine demographic features and histopathologic distribution of parotid neoplasms in a large sample from Turkey. MATERIALS AND METHODS: This study was conducted retrospectively on 136 parotidectomy materials from operations between May 2009-May 2013. Age, gender, tumor diameter, histopathological diagnosis and surgical margin status were recorded. RESULTS: The benign cases were 112 (82.4%), while the malignancies were 24 (17.6%). The accuracy rate of FNAC was 91%. There were 46 (33.8%) male and 90 (66.2%) female patients. Female/ male ratio (M/F=0.5) was two, the Warthin (WT) tumor being more apparent in males (p<0.05). Pleomorphic adenoma (PA) was detected most frequently among benign pathologies at 61.6% (69/112), while the Warthin Tumor (WT) was detected as the second most frequent tumor at 20.5% (23/112). Mucoepidermoid carcinoma (MEC) and carcinoma ex pleomorphic adenoma (Ca ex PA) were detected at equal frequency at 20.8% (5/24) among malign tumors. These were followed by acinic cell carcinoma at 16.7% (4/24). While the surgical margin was positive in ten patients with malignant tumors (41.7%), all of the benign tumors were negative (p<0.01). No significant difference was detected in the age-gender of patients, tumor size and distribution of sites among benign and malignant groups (p>0.05). CONCLUSIONS: Pleomorphic adenoma is the most frequently reported benign tumor almost in all global literature. Yet, the distribution of malignant tumors displays geographical differences. Based on these data, we believe that our findings will provide a significant contribution to future epidemiological studies. We think that it will be beneficial to generate awareness on parotid tumors and ensure a fight against smoking as with all head-neck cancers.


Subject(s)
Adenoma, Pleomorphic/epidemiology , Parotid Gland/pathology , Parotid Neoplasms/epidemiology , Adenoma, Pleomorphic/pathology , Adenoma, Pleomorphic/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Male , Middle Aged , Parotid Gland/surgery , Parotid Neoplasms/pathology , Parotid Neoplasms/surgery , Parotid Region/surgery , Retrospective Studies , Tertiary Care Centers , Turkey/epidemiology , Young Adult
15.
J Craniofac Surg ; 25(3): 998-1002, 2014 May.
Article in English | MEDLINE | ID: mdl-24705234

ABSTRACT

PURPOSE: The aim of our study was to evaluate and check (analyze and compare the results) the complications of patients with benign parotid disease reconstructed with the 3 reconstructive techniques used after the removal of benign tumors of the parotid gland treated at our institution. The reconstruction of this anatomical region may include the use of superficial musculoaponeurotic system (SMAS) flap, flap of sternocleidomastoid muscle, and temporoparietal fascia flap to prevent aesthetic and functional complications. PATIENTS AND METHODS: We carried out a retrospective review of 224 patients operated on between February 2002 and March 2009 with benign primary parotid tumors. Extracapsular dissection or superficial parotidectomy was performed and then these patients were reconstructed with the 3 techniques that we used to apply at the Department of Maxillofacial Surgery in the University Federico 2 of Naples: the SMAS flap, flap of sternocleidomastoid muscle, and temporoparietal fascia flap. The statistical difference between the extracapsular dissection versus superficial parotidectomy and the statistical difference between the 3 types of flaps as concerns evaluated recurrence rate and complications were measured with the χ test. The chosen level of statistical significance was P less than 0.05. RESULTS: Out of the 224 enrolled patients, 103 were women and 121 men, with an average age of 54 years. After histopathological examination, 136 adenomas and 88 cystadenoma lymphomas were diagnosed. Enucleoresection was the surgical technique adopted in 169 cases while superficial parotidectomy was used in the remaining 55 cases. The reconstruction was performed with SMAS flap in 122 patients, with muscle flap SMC in 66 patients and temporoparietal fascia flap in 36 patients. Table 1 shows that no significant differences as concerns hematoma and wound infection were observed after extracapsular dissection and superficial parotidectomy(1.8% vs.1.8% [P > 0.05] and 1.8% vs. 5.5% [P > 0.05]). Transient facial nerve weakness, fistula, dip skin, Frey syndrome, spinal nerve injury, and facial paralysis were significantly more frequent after superficial parotidectomy than after extracapsular dissection (4.1% vs. 27.3% [P < 0.001], 1.8% vs. 10.9% [P < 0.001], 3% vs. 12.7% [P < 0.001], 0% vs. 5.5% [P < 0.001], 0% vs. 3.6% [P < 0.001], and 0% vs. 9.1% [P < 0.001], respectively). Table 3 shows that the presence of Frey syndrome is statistically significant in the first 2 comparisons, group I against group IV and group II against group V, respectively (P < 0.05 and P < 0.01). And in the first comparison between group I and IV, there was a statistically significant presence of transient facial nerve weakness (P < 0.001), fistula (P < 0.001), dip skin (P < 0.05), and facial paralysis (P < 0.001). In the second comparison between group II and group V besides the presence of Frey syndrome, there is also a statistically significant presence of transient facial nerve weakness (P < 0.05), skin depression (P < 0.05), accessory spinal nerve injury (P < 0. 01), and facial paralysis (P < 0.01). In the comparison between the third and the sixth group, there is a statistically significant presence of transient facial nerve weakness (P < 0.05), fistula (P < 0.01), and facial paralysis(P < 0.05). CONCLUSIONS: Extracapsular dissection showed similar effectiveness and fewer side effects than superficial parotidectomy, and the 3 reconstruction techniques used in this trial drastically reduce the occurrence of post-parotidectomy Frey syndrome and greatly reduce functional and aesthetic complications.


Subject(s)
Free Tissue Flaps/transplantation , Myocutaneous Flap/transplantation , Parotid Neoplasms/surgery , Parotid Region/surgery , Plastic Surgery Procedures/methods , Postoperative Complications/surgery , Adult , Female , Humans , Male , Middle Aged , Reoperation , Retrospective Studies , Sweating, Gustatory/surgery
16.
BMJ Case Rep ; 20142014 Apr 09.
Article in English | MEDLINE | ID: mdl-24717593

ABSTRACT

Myopericytoma (MPC) is a vascular neoplasm exhibiting differentiation towards perivascular cells. Variable cytoarchitechtural features are visible within MPC, and there is much overlap between MPC, myofibroma and glomus tumours. MPC have a local recurrence rate of 10-20% and malignancy has been described in a few published cases. Previously, superficial parotidectomy has been recommended for MPC but, in this case, the surgical approach was via extracapsular dissection (ECD). A 66-year-old Caucasian man presented with a palpable mass arising from the superficial lobe of the right parotid gland. Following removal by ECD, the histopathological diagnosis of MPC was made. This is the first published report describing ECD of MPC associated with the parotid gland. ECD is preferable to superficial parotidectomy for small superficial lesions such as MPC, with similar oncological outcomes and fewer functional and aesthetic complications.


Subject(s)
Dissection , Parotid Gland/surgery , Parotid Neoplasms/surgery , Parotid Region/surgery , Vascular Neoplasms/surgery , Aged , Humans , Male , Parotid Gland/blood supply , Parotid Gland/pathology , Parotid Region/blood supply , Parotid Region/pathology
17.
Rev. esp. cir. oral maxilofac ; 35(2): 83-86, abr.-jun. 2013.
Article in Spanish | IBECS | ID: ibc-112139

ABSTRACT

En la literatura indexada, solo se han descrito 29 pacientes desde 1986. La aparición de metástasis de un carcinoma renal a nivel parotídeo es un fenómeno poco frecuente. Presentamos un paciente de 61 años, que tras cinco años de la realización de una nefrectomía unilateral por un carcinoma renal de células claras, desarrolló una metástasis de localización parotídea(AU)


Metastastic spread of renal cell carcinoma to the parotid gland is rare. In the indexed literature, with only 29 patients recorded since 1986. The case of a 61-year-old patient who developed parotid metastasis of renal cell carcinoma five years after unilateral nephrectomy is reported(AU)


Subject(s)
Humans , Male , Middle Aged , Carcinoma, Renal Cell/complications , Carcinoma, Renal Cell/diagnosis , Parotid Region/pathology , Parotid Region/surgery , Parotid Region , Salivary Glands/pathology , Salivary Glands/surgery , Interferons/therapeutic use , Neoplasm Metastasis/pathology , Neoplasm Metastasis , Carcinoma, Renal Cell/physiopathology , Salivary Glands/physiopathology , Magnetic Resonance Spectroscopy/methods , Magnetic Resonance Imaging
18.
Eur Ann Otorhinolaryngol Head Neck Dis ; 130(2): 55-60, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23352731

ABSTRACT

OBJECTIVES: To describe our experience in the management of vascular malformations of the parotid area. MATERIALS AND METHODS: This was a retrospective study. Among 614 parotidectomy performed between 1998 and 2008 at our institution, 10 cases (1.6%) of vascular malformations have been identified. Clinical features and management of these patients were analyzed. RESULTS: Clinical presentation was usually related to that of a benign, slow-growing and asymptomatic tumor. There was a marked female predominance (90%). In any case, the diagnosis of vascular malformation could be obtained with certainty preoperatively. Surgical excision was performed most often referred to diagnosis. Sixty percent of vascular malformations were located in the superficial lobe of the parotid gland. On the histological we found a classic look with benign vascular proliferation of endothelial cells in the walls. The vessel lumen was either the head of a congestion or thrombosis or calcification (phleboliths). CONCLUSION: Vascular malformations of the parotid gland, rare disease, are mainly venous. The terminology is based on clinical data, scalable, histological and hemodynamic as classified by the International Society of Study of Vascular Anomaly (ISSVA). Despite advances in imaging including MRI they remain difficult to diagnose. The treatment of reference is surgical excision.


Subject(s)
Parotid Neoplasms/blood supply , Parotid Region/blood supply , Vascular Malformations/surgery , Adult , Arteriovenous Malformations/pathology , Arteriovenous Malformations/surgery , Female , Humans , Magnetic Resonance Angiography , Male , Middle Aged , Parotid Neoplasms/diagnostic imaging , Parotid Neoplasms/surgery , Parotid Region/pathology , Parotid Region/surgery , Retrospective Studies , Sex Factors , Ultrasonography , Vascular Malformations/classification , Vascular Malformations/pathology , Young Adult
19.
Pathol Int ; 61(6): 373-6, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21615614

ABSTRACT

Histiocytic sarcoma (HS) is a malignant neoplasm showing the morphological and immunophenotypic features of mature histiocytes. Reported herein is a case of HS of the parotid gland region. A 53-year-old woman noticed a swelling of the right preauricular area. Preoperative fine needle aspiration cytology showed an admixture of pleomorphic atypical cells and mature lymphocytes. She underwent total parotidectomy. Grossly, the tumor was located at the parotid gland to subcutaneous tissue, and showed infiltrative growth with massive necrosis and hemorrhage. Microscopically, the tumor was composed of marked pleomorphic cells with eosinophilic cytoplasm. Bizarre multinuclear giant cells were scattered and intermingled. Tumor cells were positive for CD68 (KP-1 and PG-M1), CD163, S-100 protein, CD1a, CD4 and CD31, but negative for CD3, CD20, CD21, CD79a, DEC205 and langerin, immunohistochemically. Monoclonal proliferation of B cells was not confirmed on polymerase chain reaction for IgH. The patient had recurrent lesions in the pelvis and stomach 5 months after parotidectomy and died of the disease 10 months after the operation.


Subject(s)
Histiocytic Sarcoma/pathology , Parotid Neoplasms/pathology , Parotid Region/pathology , Antigens, CD/analysis , Chemotherapy, Adjuvant , Diagnosis, Differential , Fatal Outcome , Female , Histiocytic Sarcoma/radiotherapy , Histiocytic Sarcoma/surgery , Humans , Immunohistochemistry , Immunophenotyping , In Situ Hybridization , Middle Aged , Parotid Neoplasms/radiotherapy , Parotid Neoplasms/surgery , Parotid Region/surgery , Polymerase Chain Reaction , Radiotherapy, Adjuvant , Time Factors
20.
Article in English | MEDLINE | ID: mdl-21131250

ABSTRACT

PURPOSE OF STUDY: Oncology of the parotid region is rich and varied, like its components. During his career, the ENT surgeon may come across such an exceptional tumor as osteolipoma. The aim of this study was to describe the rarity and the etiopathogeny of osteolipoma with parapharyngeal location. PATIENTS AND METHOD: We had the opportunity to find this uncommon tumor in a 21-year-old female patient. The mass located in the parotid region was hard, barely mobile and at first looked like a parotid tumor. Total parotidectomy with facial nerve preservation was performed. It revealed a stony and dented tumor inside the internal lobe of the parotid located in the parapharyngeal space between the vertical portion of the mandible anteriorly and the styloid apophyse posteriorly. Macroscopic examination of the piece evidenced a lipomatous mass with hard as bone nodes in its middle. Histology revealed an osteolipoma. CONCLUSION: A review of the literature shows the uncommon occurrence of this type of tumor. A few rare cases were reported among which two involving the parapharyngeal space.


Subject(s)
Facial Neoplasms/diagnosis , Lipoma/diagnosis , Parotid Neoplasms/diagnosis , Parotid Region , Pharyngeal Neoplasms/diagnosis , Diagnosis, Differential , Facial Neoplasms/pathology , Facial Neoplasms/surgery , Female , Humans , Lipoma/pathology , Lipoma/surgery , Ossification, Heterotopic/pathology , Parotid Gland/pathology , Parotid Gland/surgery , Parotid Neoplasms/pathology , Parotid Neoplasms/surgery , Parotid Region/pathology , Parotid Region/surgery , Pharyngeal Neoplasms/pathology , Pharyngeal Neoplasms/surgery , Young Adult
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