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1.
BMC Musculoskelet Disord ; 25(1): 620, 2024 Aug 03.
Article in English | MEDLINE | ID: mdl-39095720

ABSTRACT

BACKGROUND: The Internal Fixator (INFIX) is a popular method, known for its minimal invasiveness and short operation time, for treating anterior pelvic ring fractures. Studies have shown that postoperative complications may occur, including anterolateral femoral cutaneous nerve injury, the femoral nerve paralysis, and delayed fracture healing. These complications are believed to be related to surgical stimulation, an excessively long lateral end of the connecting rod, a small distance between the screw and bone surface, insufficient pre-bending of the connecting rod, and difficulties in fracture reduction. CASE PRESENTATION: We report two unique cases of lower abdominal pseudocyst complicated with suspected infection after INFIX treatment of pelvic fractures at our trauma center. Following surgical removal of the internal fixation, resolution of the cysts was observed in both patients, and subsequent postoperative follow-up revealed the absence of any residual sequelae. These cases have not been reported in previous literature reviews. DISCUSSION: The lower abdominal cysts, potentially arising from the dead space created during intraoperative placement of the INFIX rod, may increase infection risk. The etiology remains uncertain, despite the presence of abnormal inflammation markers in both cases, and staphylococcus aureus found in one. These cysts were confined to the lower abdomen, not involving the internal fixation, and hence, only the INFIX was removed. Postoperative oral cefazolin treatment was successful, with resolved pseudocysts and no subsequent discomfort. CONCLUSION: We report two unprecedented cases of post-INFIX abdominal cysts, with a suspected link to intraoperative dead space. Despite uncertain etiology, successful management involved INFIX removal and oral cefixime therapy. These findings necessitate further exploration into the causes and management of such complications.


Subject(s)
Cysts , Fracture Fixation, Internal , Fractures, Bone , Pelvic Bones , Humans , Fracture Fixation, Internal/adverse effects , Pelvic Bones/injuries , Pelvic Bones/surgery , Pelvic Bones/diagnostic imaging , Male , Cysts/etiology , Cysts/surgery , Fractures, Bone/surgery , Fractures, Bone/complications , Adult , Anti-Bacterial Agents/therapeutic use , Female , Postoperative Complications/etiology , Postoperative Complications/diagnosis , Staphylococcal Infections/etiology , Staphylococcal Infections/diagnosis , Middle Aged
2.
BMC Geriatr ; 24(1): 657, 2024 Aug 05.
Article in English | MEDLINE | ID: mdl-39103759

ABSTRACT

BACKGROUND: Orthogeriatric co-management (OGCM) addresses the special needs of geriatric fracture patients. Most of the research on OGCM focused on hip fractures while results concerning other severe fractures are rare. We conducted a health-economic evaluation of OGCM for pelvic and vertebral fractures. METHODS: In this retrospective cohort study, we used German health and long-term care insurance claims data and included cases of geriatric patients aged 80 years or older treated in an OGCM (OGCM group) or a non-OGCM hospital (non-OGCM group) due to pelvic or vertebral fractures in 2014-2018. We analyzed life years gained, fracture-free life years gained, healthcare costs, and cost-effectiveness within 1 year. We applied entropy balancing, weighted gamma and two-part models. We calculated incremental cost-effectiveness ratios and cost-effectiveness acceptability curves. RESULTS: We included 21,036 cases with pelvic (71.2% in the OGCM, 28.8% in the non-OGCM group) and 33,827 with vertebral fractures (72.8% OGCM, 27.2% non-OGCM group). 4.5-5.9% of the pelvic and 31.8-33.8% of the vertebral fracture cases were treated surgically. Total healthcare costs were significantly higher after treatment in OGCM compared to non-OGCM hospitals for both fracture cohorts. For both fracture cohorts, a 95% probability of cost-effectiveness was not exceeded for a willingness-to-pay of up to €150,000 per life year or €150,000 per fracture-free life year gained. CONCLUSION: We did not obtain distinct benefits of treatment in an OGCM hospital. Assigning cases to OGCM or non-OGCM group on hospital level might have underestimated the effect of OGCM as not all patients in the OGCM group have received OGCM.


Subject(s)
Cost-Benefit Analysis , Osteoporotic Fractures , Spinal Fractures , Humans , Aged, 80 and over , Male , Female , Retrospective Studies , Cost-Benefit Analysis/methods , Spinal Fractures/therapy , Spinal Fractures/economics , Osteoporotic Fractures/economics , Osteoporotic Fractures/therapy , Osteoporotic Fractures/epidemiology , Health Care Costs , Germany/epidemiology , Pelvic Bones/injuries
4.
BMJ Open ; 14(8): e083809, 2024 Aug 13.
Article in English | MEDLINE | ID: mdl-39142675

ABSTRACT

INTRODUCTION: Patients with pelvic fragility fractures suffer from high morbidity and mortality rates. Despite the high incidence, there is currently no regional or nationwide treatment protocol which results in a wide variety of clinical practices. Recently, there have been new insights into treatment strategies, such as early diagnosis and minimally invasive operative treatment. The aim of this study is to implement an evidence-based and experience-based treatment clinical pathway to improve outcomes in this fragile patient population. METHODS AND ANALYSIS: This study will be a regional stepped-wedge cluster randomised controlled trial. All older adult patients (≥50 years old) who suffered a pelvic fragility fracture after low-energetic trauma are eligible for inclusion. The pathway aims to optimise the diagnostic process, to guide the decision-making process for further treatment (eg, operative or conservative), to structure the follow-up and to provide guidelines on pain management, weight-bearing and osteoporosis workup. The primary outcome is mobility, measured by the Parker Mobility Score. Secondary outcomes are mobility measured by the Elderly Mobility Scale, functional performance, quality of life, return to home rate, level of pain, type and dosage of analgesic medications, the number of falls after treatment, the number of (fracture-related) complications, 1-year and 2-year mortality. Every 6 weeks, a cluster will switch from current practice to the clinical pathway. The aim is a total of 393 inclusions, which provides an 80% statistical power for an improvement in mobility of 10%, measured by the Parker mobility score. ETHICS AND DISSEMINATION: The Medical Research Ethics Committee of Academic Medical Center has exempted the PELVIC study from the Medical Research Involving Human Subjects Act (WMO). Informed consent will be obtained using the opt-out method and research data will be stored in a database and handled confidentially. The final study report will be shared via publication without restrictions from funding parties and regardless of the outcome. TRIAL REGISTRATION NUMBER: NCT06054165. PROTOCOL VERSION: V.1.0, 19 July 2022.


Subject(s)
Pelvic Bones , Humans , Pelvic Bones/injuries , Aged , Critical Pathways , Middle Aged , Randomized Controlled Trials as Topic , Female , Male , Quality of Life , Osteoporotic Fractures/therapy , Multicenter Studies as Topic , Pain Management/methods
5.
J Orthop Trauma ; 38(9): 459-465, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39150296

ABSTRACT

OBJECTIVES: To identify the infection rate in patients with combined pelvic ring and bladder injuries. Secondary aims included identifying treatment and injury factors associated with infection. DESIGN: Retrospective review. SETTING: Single Level I Tertiary Academic Center. PATIENTS SELECTION CRITERIA: All patients over a 12-year period with combined pelvic ring and bladder injuries were evaluated. Exclusion criteria were nonoperative management of the pelvic ring, isolated posterior fixation, and follow-up <90 days. OUTCOME MEASURE AND COMPARISONS: Primary outcome measured was deep infection of the anterior pelvis requiring surgical irrigation and debridement. RESULTS: In total, 106 patients with anterior stabilization of the pelvis in the setting of a bladder injury were included. Seven patients (6.6%) developed a deep infection and required surgical debridement within 90 days. Patients undergoing open reduction and internal fixation with plating of the anterior pelvis and acute concomitant bladder repair had an infection rate of 2.2% (1/43). Patients undergoing closed reduction and anterior fixation with either external fixation or percutaneous rami screw after bladder repair had an infection rate of 17.6% (3/17). There was a higher infection rate among patients with combined intraperitoneal (IP) and extraperitoneal (EP) bladder injuries (23%) when compared with those with isolated EP (3.8%) or IP (9.1%) bladder injuries (P = 0.029). CONCLUSIONS: Acute open reduction and internal fixation of the anterior pelvis in patients with combined pelvic ring and bladder injuries has a low infection rate. Patients with combined IP and EP bladder injuries are at increased risk of infection compared with those with isolated IP and EP injuries. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fractures, Bone , Pelvic Bones , Urinary Bladder , Humans , Male , Pelvic Bones/injuries , Retrospective Studies , Female , Urinary Bladder/injuries , Urinary Bladder/surgery , Adult , Middle Aged , Fractures, Bone/surgery , Fractures, Bone/complications , Fracture Fixation, Internal/adverse effects , Risk Factors , Young Adult , Surgical Wound Infection/epidemiology , Surgical Wound Infection/etiology , Debridement , Aged , Multiple Trauma/surgery , Treatment Outcome
6.
J Orthop Trauma ; 38(9): 466-471, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39150297

ABSTRACT

OBJECTIVES: To determine the effect of obesity on systemic complications after operative pelvic ring injuries. DESIGN: Retrospective cohort study. SETTING: Single level 1 trauma center. PATIENT SELECTION CRITERIA: All patients at a level 1 trauma center who underwent operative fixation of a pelvic ring injury from 2015 to 2022 were included. Patients were grouped based on body mass index (BMI) into 4 categories (normal = BMI <25, overweight = BMI 25-30, obese = BMI 30-40, and morbidly obese BMI >40). OUTCOME MEASURES AND COMPARISONS: Systemic complications including acute respiratory distress syndrome, pneumonia, sepsis, deep venous thrombosis (DVT), pulmonary embolism, ileus, acute kidney injury (AKI), myocardial infarction, and mortality were recorded. Patients who developed a complication were compared with those who did not regarding demographic and clinical parameters to determine risk factors for each complication. RESULTS: A total of 1056 patients underwent pelvic ring fixation including 388 normal BMI, 267 overweight, 289 obese, and 112 morbidly obese patients. The average age of all patients was 36.9 years, with a range from 16 to 85 years. Overall, 631 patients (59.8%) were male. The overall complication and mortality rates were 23.2% and 1.4%, respectively. BMI was a significant independent risk factor for all-cause complication with an odds ratio of 1.67 for overweight, 2.30 for obese, and 2.45 for morbidly obese patients. The risk of DVT and AKI was also significantly increased with every weight class above normal with ORs of 5.06 and 3.02, respectively, for morbidly obese patients (BMI >40). CONCLUSIONS: This study demonstrated that among patients undergoing pelvic ring fixation, higher BMI was associated with increased risks of overall complication, specifically DVT and AKI. As the prevalence of obesity continues to increase in the population, surgeons should be cognizant that these patients may be at higher risk of certain postoperative complications during the initial trauma admission. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Fractures, Bone , Obesity , Pelvic Bones , Postoperative Complications , Humans , Male , Female , Middle Aged , Adult , Pelvic Bones/injuries , Retrospective Studies , Fractures, Bone/surgery , Fractures, Bone/complications , Aged , Postoperative Complications/epidemiology , Postoperative Complications/etiology , Obesity/complications , Aged, 80 and over , Young Adult , Adolescent , Risk Factors , Body Mass Index , Fracture Fixation, Internal/adverse effects , Cohort Studies
7.
Sci Rep ; 14(1): 17681, 2024 07 30.
Article in English | MEDLINE | ID: mdl-39085304

ABSTRACT

To determine the presence of a consistent osseous corridor from the lateral-posterior aspect of the anterior inferior iliac spine to the sacral wing that could be used for safe trans percutaneous screw fixation for pelvic fragility fractures of the iliac wing and fracture dislocations of the sacroiliac joint (FFP types IIIa and IIIb). Computed tomography (CT) scans were obtained from 100 patients and imported to Mimics software for 3D reconstruction. Then, a cylinder was drawn to imitate the modified LC-II screw and adjusted to a maximum radius and length to obtain the feasible region. Thirteen parameters of the osseous corridor of the modified LC-II screw were measured. Differences between sex groups were compared, and significant statistical correlations were carefully studied to determine potentially important clinical relationships. The records of patients with FFP type IIIa and IIIb fragility fractures of the pelvis were extracted from our hospital. Patients who underwent modified LC-II screw fixation, LC-II screw fixation or reconstruction plate fixation were included. Patients' operative characteristics and complications were recorded at follow-up. Fracture reduction quality was assessed using the Matta standard. Functional outcomes were evaluated using the Majeed grading system. The mean maximum diameters of the osseous corridors of the modified LC-II screw in males and females were 12.73 and 10.83 mm, respectively. The mean maximum lengths of the osseous corridors of the modified LC-II screw in males and females were 96.37 and 93.37 mm, respectively. In the treatment of patients with FFP IIIa and FFP IIIb fractures, the group of treatment by the modified LC-II screws fixation was shown significantly shorter operative time and fewer intraoperative blood loss in comparison to that by the reconstruction plates. In the present study, all the males and females had a complete osseous corridor of the modified LC-II screw. The clinical results of the patients who were treated with modified LC-II screw fixation suggest that the novel method has a good preliminary outcome.


Subject(s)
Bone Screws , Fracture Fixation, Internal , Pelvic Bones , Humans , Female , Male , Aged , Fracture Fixation, Internal/methods , Fracture Fixation, Internal/instrumentation , Middle Aged , Pelvic Bones/injuries , Pelvic Bones/surgery , Pelvic Bones/diagnostic imaging , Aged, 80 and over , Tomography, X-Ray Computed , Fractures, Bone/surgery , Fractures, Bone/diagnostic imaging , Ilium/surgery , Treatment Outcome , Sacroiliac Joint/surgery , Sacroiliac Joint/diagnostic imaging , Sacroiliac Joint/injuries
8.
J Orthop Trauma ; 38(9): 472-476, 2024 Sep 01.
Article in English | MEDLINE | ID: mdl-39016440

ABSTRACT

OBJECTIVES: To compare outcomes of nonoperative and percutaneous fixation of geriatric fragility lateral compression 1 (LC1) pelvic ring fractures. DESIGN: Retrospective. SETTING: Two level 1 trauma centers. PATIENT SELECTION CRITERIA: Included were patients who were 60 years or older with an isolated LC1 pelvic ring fracture managed nonoperatively or those who failed mobilization and were managed operatively with percutaneous sacral fixation. Patients with high-energy mechanisms of injury or polytrauma were excluded. OUTCOME MEASURES AND COMPARISONS: The primary outcome was pain as measured by using the visual analog scale (VAS) after treatment. Secondary outcomes included length of stay, discharge disposition, mortality, readmission rates, and complications. RESULTS: In total, 231 patients were included with a mean age of 79.5 years (range 60-100). One hundred eighty-five (80.0%) patients were female. Sixty-two (26.8%) patients received percutaneous sacral fixation after failed mobilization, and 169 (73.2%) were managed nonoperatively. In the operative group, the median time to surgery was hospital day 4. Nonoperative patients were older (81.5 ± 10.0 years vs. 74.2 ± 9.4 years, P < 0.01) and had a shorter hospital length of stay (4.8 ± 6.2 days) than the operative group (10.6 ± 9.5 days, P < 0.01). Patients in the operative group had more pain (VAS 7.9 ± 3.0) than those in the nonoperative group (VAS 6.6 ± 3.0) ( P = 0.01) on admission but had similar pain control postoperatively (VAS 4.4 ± 3.0) compared with the nonoperative group (VAS 4.5 ± 3.6) on the equivalent hospital day ( P = 0.91). Thus, patients in the operative group experienced more improvement in pain (VAS 3.3 ± 2.7) compared with the nonoperative group (VAS 1.9 ± 3.9) after treatment ( P = 0.02). Ninety-day mortality ( P = 0.21) and readmission rates ( P = 0.27) were similar for both groups. Two patients in the operative cohort sustained nerve injuries, whereas 1 patient in the nonoperative group had a nonunion and underwent surgery. CONCLUSIONS: Patients who undergo percutaneous surgical fixation for low-energy LC1 injuries have similar discharge disposition, mortality, complication rates, and readmission rates compared with patients treated nonoperatively. Percutaneous surgical fixation may provide significant pain relief for patients who failed conservative management. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Pelvic Bones , Humans , Female , Male , Aged , Pelvic Bones/injuries , Retrospective Studies , Aged, 80 and over , Middle Aged , Treatment Outcome , Fracture Fixation, Internal/methods , Fractures, Bone/surgery , Fractures, Bone/therapy , Length of Stay/statistics & numerical data
9.
BMJ Case Rep ; 17(7)2024 Jul 18.
Article in English | MEDLINE | ID: mdl-39025796

ABSTRACT

Anal squamous cell carcinoma, typically associated with human papillomavirus infection, remains a rare malignancy. This article outlines a case of local recurrence in a male patient with a history of HIV and hepatitis C virus infection, previously treated with chemoradiotherapy. Extensive tumour involvement called for total pelvic exenteration extended to anterior osteomuscular compartment and genitalia. The surgical approach involved multidisciplinary collaboration and detailed preoperative planning using three-dimensional reconstruction. Key surgical considerations comprised the following: achieving tumour-free margins (R0 resection), extensive osteotomies and intricate pelvic floor reconstruction with prosthetic mesh and flap reconstruction. The procedure successfully yielded an R0 resection, maintaining adequate lower limb functionality. Our case report underscores the benefits of pelvic exenteration in locally advanced or recurrent pelvic tumours, invariably following careful patient selection and exhaustive preoperative studies.


Subject(s)
Anus Neoplasms , Carcinoma, Squamous Cell , Chemoradiotherapy , Neoplasm Recurrence, Local , Pelvic Bones , Pelvic Exenteration , Plastic Surgery Procedures , Surgical Flaps , Humans , Male , Anus Neoplasms/therapy , Anus Neoplasms/surgery , Carcinoma, Squamous Cell/therapy , Carcinoma, Squamous Cell/surgery , Neoplasm Recurrence, Local/surgery , Chemoradiotherapy/methods , Pelvic Bones/surgery , Plastic Surgery Procedures/methods , Middle Aged
10.
Front Public Health ; 12: 1428068, 2024.
Article in English | MEDLINE | ID: mdl-39040861

ABSTRACT

Background: This study explored the epidemiological trends in pelvic fracture (PF) in China from 1992 to 2021, analyze their relationships with age-period-cohort (APC) factors, and predict the trends of PF from 2022 to 2046. Methods: Incidence and years lived with disabilities (YLDs) of PF among sexes in China from 1992 to 2021 were obtained through the 2021 Global Burden of Disease (GBD) database. Trends in the incidence and YLDs were described, and a joinpoint regression model was used. The APC model was used to explore the effects of age, period, and cohort on the incidence and YLDs. Nordpred forecasted the incidence and YLDs in China from 2022 to 2046. Results: In 2021, there were an estimated 0.63 million incidence cases and 0.33 million of YLDs, respectively. The number and age-standardized rate (ASR) of incidence and YLDs were both gradually increased. The average annual percent change (AAPC) in incidence and YLDs for men were 0.26% and -0.17%, respectively. For women, the AAPC values for incidence and YLDs were -0.03% and -0.57% (p < 0. 001), respectively. The relative risk (RR) of PF increases with age, with the lowest risk in those aged 10-14 years for incidence and aged 1-4 for YLDs and the highest risk in those aged >95 years for incidence and aged 90-94 years for YLDs. The period effect showed a totally increase in the risk across the general, male, and female populations. Cohort effects indicated a totally significant decline for both incidence and YLDs. The predicted incidence and YLDs of PF in China from 2022 to 2046 showed an initial rise, followed by a decline, with 2029 and 2034 being the turning point for incidence and YLDs, respectively. Conclusion: The characteristics of pelvic fracture incidence and YLDs in China are complex. Thus, primary prevention measures must be strengthened. Raising awareness about osteoporosis prevention, enhancing public health education, and promoting good dietary and hygiene habits are appropriate preventive measures for PF in China.


Subject(s)
Forecasting , Fractures, Bone , Pelvic Bones , Humans , China/epidemiology , Male , Female , Middle Aged , Fractures, Bone/epidemiology , Aged , Incidence , Adult , Pelvic Bones/injuries , Adolescent , Aged, 80 and over , Cohort Studies , Child , Young Adult , Child, Preschool , Infant , Age Factors , Global Burden of Disease/trends
11.
J Orthop Surg Res ; 19(1): 419, 2024 Jul 20.
Article in English | MEDLINE | ID: mdl-39033130

ABSTRACT

BACKGROUND: Fundamental morphologic differences between male and female pelvises are historically recognised. Despite this, little consideration has been given as to whether or not conventional positioning supports used for primary total hip arthroplasties (THAs) performed in the lateral position do an equally effective job of maintaining the intended set up position when comparing genders. Given that recent research has highlighted that unintended pelvic roll occurs commonly during hip surgery, and that such movement may have a mechanically-deleterious consequence upon final construct performance and complication rates, this study was undertaken to explore the differences in pelvic roll between genders. METHODS: The output of a high-precision, commercially-available, imageless intra-operative navigation system was prospectively-collected for 85 consecutive patients undergoing unilateral, primary THAs. These data were separated by gender and were utilised to determine differences in pelvic movement around a central sagittal axis. RESULTS: Demographic data were similar between genders, with no between-group differences in mean BMI (p = 0.09) or indication for surgery (p = 0.66), however participating males (mean 68.04) were slightly younger than females (mean 73.31). The mean anterior pelvic roll for females was 9.50°, and for males 8.68°. There were no statistically significant independent correlations observed between gender (p = 0.21) and pelvic roll. CONCLUSION: The findings of this novel study do not suggest gender differences in the magnitude of unintended, intra-operative, anterior roll, even when corrected for BMI and surgical indication. Average roll of ~ 9° was demonstrated across both groups. An awareness of such positional change during THA surgery may reduce potentially-avoidable post-operative complications.


Subject(s)
Arthroplasty, Replacement, Hip , Patient Positioning , Humans , Male , Female , Arthroplasty, Replacement, Hip/methods , Arthroplasty, Replacement, Hip/adverse effects , Aged , Middle Aged , Patient Positioning/methods , Prospective Studies , Sex Characteristics , Aged, 80 and over , Sex Factors , Pelvic Bones/surgery , Pelvis/surgery
12.
Semin Musculoskelet Radiol ; 28(4): 437-446, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39074726

ABSTRACT

The development of the pelvis follows a predictable pattern of ossification that involves the maturation of bone, synchondroses, and apophyses. These growth centers appear and close at distinct times during skeletal maturity and give rise to structural changes in the pelvis that can be distinctively appreciated on various imaging modalities. Accurate interpretation of radiologic images requires knowledge of skeletal development because the varying appearance of the maturing pediatric pelvis may be mistaken for pathology. In addition, many normal features within the pelvis can be erroneously perceived as injury. This article incorporates a multimodality review of normal pelvic maturation, a discussion of developmental variants, and a description of common injuries unique to the pediatric pelvis.


Subject(s)
Pelvic Bones , Humans , Child , Pelvic Bones/diagnostic imaging , Pelvic Bones/injuries , Pelvis/diagnostic imaging , Child, Preschool , Infant , Diagnostic Imaging/methods
13.
Bone Joint J ; 106-B(8): 865-870, 2024 Aug 01.
Article in English | MEDLINE | ID: mdl-39084652

ABSTRACT

Aims: Venous tumour thrombus (VTT) is a rare finding in osteosarcoma. Despite the high rate of VTT in osteosarcoma of the pelvis, there are very few descriptions of VTT associated with extrapelvic primary osteosarcoma. We therefore sought to describe the prevalence and presenting features of VTT in osteosarcoma of both the pelvis and the limbs. Methods: Records from a single institution were retrospectively reviewed for 308 patients with osteosarcoma of the pelvis or limb treated between January 2000 and December 2022. Primary lesions were located in an upper limb (n = 40), lower limb (n = 198), or pelvis (n = 70). Preoperative imaging and operative reports were reviewed to identify patients with thrombi in proximity to their primary lesion. Imaging and histopathology were used to determine presence of tumour within the thrombus. Results: Tumours abutted the blood vessels in 131 patients (43%) and encased the vessels in 30 (10%). Any form of venous thrombus was identified in 31 patients (10%). Overall, 21 of these thrombi were determined to be involved with the tumour based on imaging (n = 9) or histopathology (n = 12). The rate of VTT was 25% for pelvic osteosarcoma and 1.7% for limb osteosarcoma. The most common imaging features associated with histopathologically proven VTT were enhancement with contrast (n = 12; 100%), venous enlargement (n = 10; 83%), vessel encasement (n = 8; 66%), and visible intraluminal osteoid matrix (n = 6; 50%). Disease-specific survival (DSS) for patients with VTT was 95% at 12 months (95% CI 0.87 to 1.00), 50% at three years (95% CI 0.31 to 0.80), and 31% at five years (95% CI 0.14 to 0.71). VTT was associated with worse DSS (hazard ratio 2.3 (95% CI 1.11 to 4.84). Conclusion: VTT is rare with osteosarcoma and occurs more commonly in the pelvis than the limbs. Imaging features suggestive of VTT include enhancement with contrast, venous dilation, and vessel encasement. VTT portends a worse prognosis for patients with osteosarcoma, with a similar survivability to metastatic disease.


Subject(s)
Bone Neoplasms , Osteosarcoma , Venous Thrombosis , Humans , Osteosarcoma/pathology , Osteosarcoma/mortality , Osteosarcoma/complications , Male , Female , Bone Neoplasms/pathology , Retrospective Studies , Adult , Adolescent , Middle Aged , Child , Young Adult , Venous Thrombosis/pathology , Venous Thrombosis/diagnostic imaging , Pelvic Bones/pathology , Pelvic Bones/diagnostic imaging , Aged , Extremities/blood supply
14.
J Med Case Rep ; 18(1): 346, 2024 Jul 29.
Article in English | MEDLINE | ID: mdl-39069618

ABSTRACT

BACKGROUND: Ewing's sarcoma is a primary bone tumor predominantly observed in children and adolescents, necessitating a multidisciplinary treatment approach. While localized cases have a 5-year survival rate of 60-70%, the prognosis is significantly worse in pelvic advanced cases with metastasis. Moreover, pelvic Ewing's sarcoma has the unique problem of leading to high rates of postoperative infection. CASE PRESENTATION: We present the case of a Japanese 14-year-old boy with left iliac Ewing's sarcoma and multiple metastases. At the initial visit, imaging revealed a large tumor in the left iliac bone with extraosseous extension and metastasis to multiple sites. Neoadjuvant chemotherapy resulted in significant tumor reduction. Surgical resection was performed without pelvic ring reconstruction to enable early postoperative chemotherapy and minimize postoperative infection risk. Despite complete abductor muscle removal, the patient achieved a stable gait postoperatively by centering the load axis. CONCLUSION: Our case highlights the successful management of a left iliac Ewing's sarcoma with multiple metastases, with a focus on functional preservation and infection risk reduction. Pelvic ring reconstruction was not performed to avoid postoperative complications, emphasizing the importance of early postoperative chemotherapy. The patient achieved a stable gait postoperatively, demonstrating the potential benefits of this approach in similar cases.


Subject(s)
Bone Neoplasms , Ilium , Sarcoma, Ewing , Walking , Humans , Sarcoma, Ewing/surgery , Male , Bone Neoplasms/surgery , Bone Neoplasms/secondary , Adolescent , Ilium/transplantation , Pelvic Bones/surgery , Pelvic Bones/diagnostic imaging , Plastic Surgery Procedures/methods , Treatment Outcome , Neoadjuvant Therapy
15.
Unfallchirurgie (Heidelb) ; 127(8): 607-612, 2024 Aug.
Article in German | MEDLINE | ID: mdl-38990311

ABSTRACT

The challenge in treating traumatic hemipelvectomy is the dynamics of the complex and life-threatening consequences of the injury. These include skin and soft tissue defects, osseous, neural and vascular injuries as well as the subsequent hemostatic derangement and organ dysfunction as part of the shock process. The treatment requires rapid and targeted decisions to save the patient's life. In this particular case a 34-year-old farmer was trapped between a wheeled loader and a stationary trailer. Upon arrival at the hospital the patient was in a state of hemorrhagic shock with accompanying acute traumatic coagulopathy and a grade III open pelvic trauma with complete ischemia of the left leg and a bladder injury. After performing emergency surgery and a two-stage approach for pelvic stabilization the patient's condition deteriorated up to multiorgan failure, necessitating left-sided hemipelvectomy as an immediate life-saving salvage procedure. In the further course multiple revision surgeries and plastic reconstructions due to wound infections and the presence of skin and soft tissue damage were required. Due to the rare confrontation with this type of injury in everyday practice and the absence of a universal treatment algorithm, the following case report is intended to contribute to a better understanding of the treatment and to illustrate the coherent interactions of the individual organ systems affected.


Subject(s)
Hemipelvectomy , Humans , Adult , Male , Hemipelvectomy/methods , Multiple Trauma/surgery , Treatment Outcome , Pelvic Bones/injuries , Pelvic Bones/surgery , Leg Injuries/surgery , Acute Care Surgery
16.
Anat Histol Embryol ; 53(4): e13092, 2024 Jul.
Article in English | MEDLINE | ID: mdl-39012157

ABSTRACT

The ossa coxae are the bones that connect the hindlimbs to the axial skeleton. The right and left os coxae join at the median plane to form the pelvis. In this study, variations in pelvis shape and the asymmetric structure of the pelvis were investigated across different classes of dogs. To achieve this, computed tomography images of the pelvis were obtained from 35 dogs, and 3D modelling of the pelvis was created. Subsequently, 45 landmarks were identified on these models. As a result of the Principal Component Analysis, the shape variation was observed in the pelvic canal and crista iliaca. Directional asymmetry between Principal Component 1 and Principal Component 2 accounted for 33.84% of the total variation, while fluctuating asymmetry contributed 23.66%. Canonical variate analysis revealed that canonical variate (CV) 1 explained 56.56% of the total variation between groups, with CV 2 explained 28.98%. Male dogs exhibited greater pelvic variation than females. Procrustes ANOVA indicated that the greatest proportion of shape variation corresponds to the effect of differences among individuals. While directional asymmetry was statistically significant, fluctuating asymmetry was not. Male dogs displayed more pronounced pelvic shape asymmetry, typically towards the right. Gundogs had a narrower pelvic canal and a wide crista iliaca, whereas terriers had a wider pelvic canal and smaller crista iliaca in shape. Geometric morphometry enables statistical analysis and the derivation of average shapes from samples, making it a vital tool in veterinary anatomy. This study provides insights into pelvic geometric morphometry across different classes of dogs.


Subject(s)
Pelvic Bones , Pelvis , Principal Component Analysis , Tomography, X-Ray Computed , Animals , Dogs/anatomy & histology , Male , Female , Tomography, X-Ray Computed/veterinary , Pelvic Bones/anatomy & histology , Pelvis/anatomy & histology , Pelvis/diagnostic imaging , Imaging, Three-Dimensional/veterinary
17.
J Am Acad Orthop Surg ; 32(14): e683-e694, 2024 Jul 15.
Article in English | MEDLINE | ID: mdl-38967987

ABSTRACT

Surgical fixation of pediatric pelvic ring injuries is gaining popularity to avoid the poor long-term outcomes of pelvic asymmetry. The surgical techniques and fixation choices depend on the individual injuries affecting the anterior and posterior pelvic ring areas. The immature bony pelvis of young children has anatomic differences including soft bones, elastic ligaments, and the presence of growth centers. Understanding the unique pediatric lesions with unstable pelvic fractures is essential for treatment decisions. Anterior lesions include pubic symphysis disruption through the pubic apophysis, single ramus fractures, pubic rami fractures through the triradiate cartilage, and/or the ischiopubic synchondrosis; ischiopubic ramus infolding injury; or the unstable superior and inferior quadrant lesions. Posterior pelvic lesions include iliac wing infolding and sacroiliac joint dislocation or transiliac (crescent) fracture/dislocations through the iliac apophysis growth plate. Pubic symphysis and sacroiliac disruptions are physeal injuries in children, and they have excellent healing potential. External fixation is an ideal choice for anterior ring fixation including bony and pubic symphysis injuries. Posterior lesions are mostly sacroiliac joint disruptions with iliac apophysis separation that can serve as a landmark for vertical displacement correction. Posterior lesions can be treated by percutaneous iliosacral screw fixation or open reduction techniques.


Subject(s)
Fractures, Bone , Pelvic Bones , Humans , Fractures, Bone/surgery , Fractures, Bone/diagnostic imaging , Pelvic Bones/injuries , Pelvic Bones/surgery , Child , Sacroiliac Joint/injuries , Sacroiliac Joint/surgery , Fracture Fixation/methods , Fracture Fixation, Internal/methods , Pubic Symphysis/injuries
18.
J Orthop Trauma ; 38(8): 426-430, 2024 Aug 01.
Article in English | MEDLINE | ID: mdl-39007658

ABSTRACT

OBJECTIVES: To determine the effectiveness of an updated protocol that increased the transfusion threshold to perform preperitoneal pelvic packing in patients with pelvic ring injuries and hemodynamic instability (HDI). DESIGN: Retrospective review. SETTING: Urban level 1 trauma center. PATIENTS SELECTION CRITERIA: Severely injured (injury severity score > 15) patients with pelvic ring injuries treated before and after increasing the threshold to perform preperitoneal pelvic packing from 2 to 4 units of red blood cells (RBCs). HDI was defined as a systolic blood pressure <90 mm Hg. OUTCOME MEASURES AND COMPARISONS: Mortality from hemorrhage, anterior pelvic space infections, and venous thromboembolisms before and after increasing preperitoneal pelvic packing threshold. RESULTS: One hundred sixty-six patients were included: 93 treated under the historical protocol and 73 treated under the updated protocol. HDI was present in 46.2% (n = 43) of the historical protocol group and 49.3% (n = 36) of the updated protocol group (P = 0.69). The median age of patients with HDI was 35.0 years (interquartile range 26.0-52.0), 74.7% (n = 59) were men, and the median injury severity score was 41.0 (interquartile range 29.0-50.0). Patients with HDI in the updated protocol group had a lower heart rate on presentation (105.0 vs. 120.0; P = 0.004), required less units of RBCs over the first 24 hours (6.0 vs. 8.0, P = 0.03), and did not differ in age, injury severity score, systolic blood pressure on arrival, base deficit or lactate on arrival, resuscitative endovascular balloon occlusion of the aorta, resuscitative thoracotomy, angioembolization, or anterior pelvis open reduction internal fixation (P > 0.05). The number of PPPs performed decreased under the new protocol (8.3% vs. 65.1%, P < 0.0001), and there were fewer anterior pelvic infections (0.0% vs. 13.9%, P = 0.02), fewer VTEs (8.3% vs. 30.2%; P = 0.02), and no difference in deaths from acute hemorrhagic shock (5.6% vs. 7.0%, P = 1.00). CONCLUSIONS: Increasing the transfusion threshold from 2 to 4 units of red blood cells to perform pelvic packing in severely injured patients with pelvic ring injuries decreased anterior pelvic space infections and venous thromboembolisms without affecting deaths from acute hemorrhage. LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Pelvic Bones , Humans , Male , Female , Adult , Retrospective Studies , Middle Aged , Pelvic Bones/injuries , Treatment Outcome , Hemorrhage/mortality , Hemorrhage/prevention & control , Blood Transfusion/statistics & numerical data , Fractures, Bone/surgery , Hemostatic Techniques , Injury Severity Score
19.
Biomed Eng Online ; 23(1): 66, 2024 Jul 12.
Article in English | MEDLINE | ID: mdl-38997736

ABSTRACT

BACKGROUND: Management of inferior ramus of the pubis-ischium ramus remains controversial, and related research is sparse. The main intention of this study is to describe the biomechanical and clinical outcomes of pubis-ischium ramus fractures in Tile B pelvic injuries and to identify the feasibility and necessity of fixation of the inferior ramus of the pubis-ischium ramus. METHODS: This study comprised two parts: a biomechanical test and a retrospective clinical study. For the biomechanical tests, Tile B-type pelvic injuries were modeled in six cadaver specimens by performing pubis-ischium osteotomies and disruption of the anterior and interosseous sacroiliac ligaments. The superior and/or inferior rami of the pubis-ischium ramus were repaired with reconstruction plates and separated into three groups (A, B, and C). Specimens were placed in the standing position and were loaded axially with two-leg support for three cycles at 500 N. The displacements of sacroiliac joints at osteotomy were measured with Vernier calipers and compared using statistical software. To investigate the clinical outcomes of this technique, 26 patients were retrospectively analyzed and divided into a superior ramus fixation group (Group D) and a combined superior and inferior ramus of the pubis-ischium ramus fixation group (Group E). The main outcome measures were time of operation, blood loss, postoperative radiographic reduction grading, and functional outcomes. RESULTS: In the vertical loading test, Group E showed better pelvic ring stability than Group D (P < 0.05). However, the shift of the sacroiliac joints was almost identical among the three groups. In our clinical case series, all fractures in Group E achieved bony union. Group E demonstrated earlier weight-bearing functional exercise (2.54 ± 1.45 vs 4.77 ± 2.09; P = 0.004), earlier bony union (13.23 ± 2.89 vs 16.55 ± 3.11; P = 0.013), and better functional outcomes (89.77 ± 7.27 vs 82.38 ± 8.81; P = 0.028) than Group D. The incidence of sexual dysfunction was significantly lower in Group E than that in Group D (2/13 vs 7/13; P = 0.039). Bone nonunion occurred in two patients in Group D, and two patients in Group E had heterotopic ossification. None of the patients exhibited wound complications, infections, implant failures, or bone-implant interface failures. CONCLUSIONS: Fixation of the inferior ramus of a pubis-ischium ramus fracture based on conventional fixation of the anterior pelvic ring is mechanically superior in cadaveric Tile B pelvic injury and shows rapid recovery, good functional outcomes, and low incidence of complications.


Subject(s)
Bone Plates , Pelvic Bones , Humans , Biomechanical Phenomena , Male , Female , Adult , Pelvic Bones/surgery , Pelvic Bones/injuries , Pelvic Bones/diagnostic imaging , Middle Aged , Mechanical Phenomena , Cadaver , Fractures, Bone/surgery , Retrospective Studies , Fracture Fixation, Internal/instrumentation
20.
Medicine (Baltimore) ; 103(28): e38888, 2024 Jul 12.
Article in English | MEDLINE | ID: mdl-38996089

ABSTRACT

Malalignment is one of the most critical risk factors for knee osteoarthritis (KOA). Biomechanical factors such as knee varus or valgus, hip-knee-ankle angle, and femoral anteversion affect KOA severity. In this study, we aimed to investigate KOA severity predictive factors based on hip and pelvic radiographic geometry. In this cross-sectional study, 125 patients with idiopathic KOA were enrolled. Two investigators evaluated the knee and pelvic radiographs of 125 patients, and 16 radiological parameters were measured separately. KOA severity was categorized based on the medial tibiofemoral joint space widths (JSW). Based on JSW measurements, 16% (n = 40), 8.8% (n = 22), 16.4% (n = 41), and 56.8% (n = 147) were defined as grades 0, 1, 2, 3, respectively. There were significant differences between the JSW groups with respect to hip axis length, femoral neck-axis length, acetabular width, neck shaft angle (NSA), outer pelvic diameter, midpelvis-caput distance, acetabular-acetabular distance, and femoral head to femoral head length (P < .05). Two different functions were obtained using machine learning classification and logistic regression, and the accuracy of predicting was 74.4% by using 1 and 89.6% by using both functions. Our findings revealed that some hip and pelvic geometry measurements could affect the severity of KOA. Furthermore, logistic functions using predictive factors of hip and pelvic geometry can predict the severity of KOA with acceptable accuracy, and it could be used in clinical decisions.


Subject(s)
Osteoarthritis, Knee , Radiography , Severity of Illness Index , Humans , Osteoarthritis, Knee/diagnostic imaging , Osteoarthritis, Knee/pathology , Osteoarthritis, Knee/physiopathology , Female , Male , Cross-Sectional Studies , Middle Aged , Aged , Radiography/methods , Pelvic Bones/diagnostic imaging , Knee Joint/diagnostic imaging , Knee Joint/pathology , Knee Joint/physiopathology , Risk Factors , Pelvis/diagnostic imaging , Pelvis/pathology , Adult
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