ABSTRACT
Laser microanalysis has been applied to the study of pathogenic fungi. Such a method allows chemical information to be obtained and permits the detection of 74 elements in the periodic system of Mendeleev from lithium (3) to uranium (92).
Subject(s)
Ascomycota/analysis , Lasers , Phialophora/analysis , Spectrum Analysis/methods , Trace Elements/analysis , Humans , Mycoses/microbiologyABSTRACT
The (-)-enantiomer of cryptosporiopsin, a chlorinated cyclopentenone fungitoxic metabolite, was isolated from Phialophora asteris f. sp. helianthi. Next to a comparable fungitoxic activity was shown by crypstosporiopsin, the product particularly inhibits growth of Sclerotinia sclerotiorum, an important pathogen on sunflower. Two further metabolites were tentatively identified as a stereoisomer of cryptosporiopsin and its dehydrated derivative.
Subject(s)
Antifungal Agents/isolation & purification , Ascomycota , Cyclopentanes/isolation & purification , Phialophora/analysis , Chemical Phenomena , Chemistry , StereoisomerismABSTRACT
We have previously isolated two chlorinated antibiotics from Phialophora asteris and P. asteris f. sp. helianthi, vascular pathogens on plants. P. cinerescens, pathogen on carnation, also presents a fungitoxic activity but the nature of the antibiotic compound is still unknown. We point out that this activity can be lost by sectorial variations on the growing margin and that the antibiotic product shows a striking photolability.
