ABSTRACT
Pilomatricomas are benign calcifying neoplasms derived from follicle matrix cells. Standard treatment for pilomatricomas involves complete surgical excision, with an overall low rate of recurrence. We discuss a simple alternative surgical technique that allows for removal of the lesion with less residual defect than complete excision.
Subject(s)
Hair Diseases/surgery , Pilomatrixoma/surgery , Skin Neoplasms/surgery , Trichloroacetic Acid/administration & dosage , Child, Preschool , Female , Hair Diseases/drug therapy , Hair Diseases/pathology , Humans , Pilomatrixoma/drug therapy , Pilomatrixoma/pathology , Skin Neoplasms/drug therapy , Skin Neoplasms/pathologyABSTRACT
No disponible
Subject(s)
Humans , Female , Child , Pilomatrixoma/chemically induced , Pilomatrixoma/complications , Pilomatrixoma/drug therapy , Methotrexate/administration & dosage , Methotrexate/adverse effects , Arthritis, Juvenile/complications , Arthritis, Juvenile/diagnosis , Pilomatrixoma/physiopathology , Arthritis, Juvenile/drug therapy , Arthritis, Juvenile/physiopathology , ApoptosisSubject(s)
Carcinosarcoma/pathology , Carcinosarcoma/surgery , Head and Neck Neoplasms/pathology , Head and Neck Neoplasms/surgery , Pilomatrixoma/pathology , Pilomatrixoma/surgery , Carcinosarcoma/drug therapy , Carcinosarcoma/radiotherapy , Combined Modality Therapy , Head and Neck Neoplasms/drug therapy , Head and Neck Neoplasms/radiotherapy , Humans , Male , Neoplasm Recurrence, Local , Pilomatrixoma/drug therapy , Pilomatrixoma/radiotherapy , Young AdultABSTRACT
We report the case of a 66-year-old patient with a pilomatrix carcinoma from the right submandibular region with pulmonary and cerebral metastases. The histological confirmation of the diagnosis has been based on the biopsy of the submandibular tumefaction which was rapidly growing. We tried at first a doxorubicine and cisplatine chemotherapy because of the considerable locoregional extension and the existence of pulmonary metastases. The patient response to three cures of chemotherapy was spectacular with a partial clinical response (75%) and a partially cleaned-up chest observed in the radiological evaluation. In the 5th cycle of chemotherapy following the same protocol, the patient presented a relapse with cerebral metastases. The patient received hypofractionated radiotherapy on the brain followed by etoposide and cisplatine chemotherapy, then oral vinorelbine. The patient died of progressive disease after 32 weeks.
