ABSTRACT
We report a 39-year-old Native American female with an almost 20-year history of dysphagia that had increased in the 6 months prior to the initial evaluation. Investigation revealed a number of distinct esophageal disorders including Plummer-Vinson syndrome, gastroesophageal reflux disease with esophagitis, distal esophageal stricture, esophageal intramural pseudo-diverticulosis, and recurrent esophageal Candida infections. Although prolonged therapy with proton pump inhibitors, fluconazole, nystatin, and repeated esophageal balloon dilations relieved her symptoms, her prognosis remains uncertain.
Subject(s)
Deglutition Disorders/etiology , Deglutition Disorders/therapy , Holistic Health , Plummer-Vinson Syndrome/complications , Plummer-Vinson Syndrome/therapy , Adult , Anemia, Iron-Deficiency/complications , Anemia, Iron-Deficiency/diagnostic imaging , Anemia, Iron-Deficiency/therapy , Deglutition Disorders/diagnostic imaging , Dilatation/methods , Endoscopy, Digestive System/methods , Female , Humans , Plummer-Vinson Syndrome/diagnostic imaging , Proton Pump Inhibitors/therapeutic use , Treatment OutcomeABSTRACT
Plummer-Vinson syndrome is a rare entity, characterized by dysphagia, esophageal web formation, and iron deficiency anemia. The patient was a 63-year-old woman with a clinical history of iron deficiency anemia and glossitis in her 20s to 40s and who had experienced swallowing difficulties for the past 20 years. A membranous stricture was found in the cervical esophagus during a fluoroscopic examination. An endoscopic examination conducted under general anesthesia revealed an oblique linear scar on the proximal surface of the stricture. Sequential balloon dilation was performed successfully. We suggest that the esophageal web formation might have been related to the healing of an esophageal ulcer.
Subject(s)
Esophagoscopy , Esophagus/diagnostic imaging , Plummer-Vinson Syndrome/diagnostic imaging , Esophagus/pathology , Female , Humans , Middle Aged , Plummer-Vinson Syndrome/pathologyABSTRACT
We report a case of Plummer-Vinson syndrome (PVS) and lower esophageal ring with a small sliding hiatal hernia. PVS is a rare entity formed by the combination of dysphagia, cervical esophageal web and iron deficiency anemia. It occurs mainly in middle-aged women1,2,3. A lower esophageal ring and a small sliding hiatal hernia were also observed in this case. We documented clinical manifestations of iron deficiency anemia through images and esophageal abnormalities through barium esophagogram. (AU)
Subject(s)
Humans , Female , Adult , Plummer-Vinson Syndrome/blood , Plummer-Vinson Syndrome/diagnostic imaging , Esophageal Sphincter, Lower/diagnostic imaging , Hernia, Hiatal/diagnostic imaging , Anemia, Iron-Deficiency/bloodABSTRACT
No disponible
Subject(s)
Humans , Female , Young Adult , Plummer-Vinson Syndrome/diagnostic imaging , Anemia, Hypochromic/diagnosis , Plummer-Vinson Syndrome/blood , Plummer-Vinson Syndrome/therapy , Deglutition Disorders/physiopathology , Cricoid Cartilage/abnormalitiesSubject(s)
Deglutition Disorders/etiology , Plummer-Vinson Syndrome/diagnosis , Deglutition Disorders/diagnosis , Deglutition Disorders/diagnostic imaging , Esophageal Stenosis/diagnosis , Esophageal Stenosis/diagnostic imaging , Esophageal Stenosis/etiology , Esophagoscopy , Esophagus/diagnostic imaging , Female , Humans , Middle Aged , Plummer-Vinson Syndrome/complications , Plummer-Vinson Syndrome/diagnostic imaging , RadiographySubject(s)
Esophagoscopy , Plummer-Vinson Syndrome/diagnostic imaging , Anemia, Hypochromic/drug therapy , Anemia, Hypochromic/etiology , Anemia, Hypochromic/therapy , Combined Modality Therapy , Deglutition Disorders/etiology , Erythrocyte Transfusion , Female , Hematinics/therapeutic use , Humans , Plummer-Vinson Syndrome/complications , Young AdultSubject(s)
Anemia, Iron-Deficiency/drug therapy , Deglutition Disorders/therapy , Hematinics/therapeutic use , Plummer-Vinson Syndrome/therapy , Administration, Oral , Adult , Anemia, Iron-Deficiency/diagnostic imaging , Barium Sulfate/administration & dosage , Contrast Media/administration & dosage , Deglutition Disorders/diagnostic imaging , Dilatation , Esophagoscopy , Female , Gastroscopy , Humans , Plummer-Vinson Syndrome/diagnostic imaging , Tomography, X-Ray Computed , Treatment OutcomeSubject(s)
Plummer-Vinson Syndrome/diagnosis , Adult , Atrophy , Endoscopy , Esophagoscopy , Female , Fluoroscopy/methods , Glossitis/etiology , Glossitis/pathology , Hematinics/therapeutic use , Humans , Iron/therapeutic use , Nail Diseases/etiology , Nail Diseases/pathology , Plummer-Vinson Syndrome/complications , Plummer-Vinson Syndrome/diagnostic imaging , Plummer-Vinson Syndrome/pathology , Plummer-Vinson Syndrome/therapy , Treatment Outcome , Video RecordingABSTRACT
Plummer-Vinson syndrome (sideropenic dysphagia) is characterized by dysphagia due to an upper esophageal or hypopharyngeal web in patients with chronic iron deficiency anemia. The main cause of dysphagia is the presence of the web in the cervical esophagus, and abnormal motility of the pharynx or esophagus is also found to play a significant role in this condition. This syndrome is thought to be precancerous because squamous cell carcinoma of hypopharynx, oral cavity or esophagus takes place in 10% of those patients suffering from this malady, but it is even more unusual that Plummer-Vinson syndrome should be accompanied by gastric cancer. We have reported here a case of a 43-year-old woman with Plummer-Vinson syndrome who developed stomach cancer and recovered after a radical total gastrectomy with D2 nodal dissection.
Subject(s)
Plummer-Vinson Syndrome/pathology , Stomach Neoplasms , Adult , Female , Humans , Plummer-Vinson Syndrome/diagnostic imaging , Plummer-Vinson Syndrome/surgery , Radiography , Stomach Neoplasms/diagnosis , Stomach Neoplasms/diagnostic imaging , Stomach Neoplasms/pathology , Stomach Neoplasms/surgeryABSTRACT
The coexistence of large diaphragmatic hernia and Plummer-Vinson syndrome in two patients is described. It is proposed that the hernias caused chronic blood loss anemia, and that iron deficiency then resulted in postcricoid web formation.