ABSTRACT
Pseudotumor cerebri syndrome is a syndrome of increased cerebrospinal fluid pressure without ventriculomegaly, mass lesion, or meningeal abnormality. It is either primary (idiopathic intracranial hypertension, IIH) or secondary. A secondary cause is unlikely when adhering to the diagnostic criteria. Permanent visual loss occurs if undetected or untreated, and the associated headaches may be debilitating. Fulminant disease may result in blindness despite aggressive treatment. This study addresses the diagnosis and management of IIH including new insights into the pathobiology of IIH, updates in therapeutics and causes of overdiagnosis.
Subject(s)
Intracranial Hypertension , Papilledema , Pseudotumor Cerebri , Humans , Pseudotumor Cerebri/diagnosis , Pseudotumor Cerebri/etiology , Pseudotumor Cerebri/therapy , Intracranial Hypertension/complications , Headache/diagnosis , Headache/etiology , Headache/therapy , Vision Disorders/therapy , Syndrome , Papilledema/complications , Papilledema/diagnosisABSTRACT
Idiopathic intracranial hypertension (IIH) is a diagnosis of exclusion characterized by features of raised intracranial pressure (ICP) in the absence of brain parenchymal lesion, vascular malformations, hydrocephalus, or central nervous system (CNS) infection. Commonly used other terms for this entity include benign intracranial hypertension (BIH) or pseudotumor cerebri. Few case reports of systemic lupus erythematosus (SLE) presenting as IIH are available in the literature. We report a 12-year-old girl presented with chronic holocranial headache and occasional episodes of projectile vomiting for the last 6 months and then developed blurring of vision for the last month. She fulfilled the criteria for IIH. Subsequent evaluation revealed a diagnosis of SLE. The occurrence of IIH in SLE is not coincidental and is reported in 1%-5.4% of patients with SLE. Though corticosteroids have not been widely used in IIH, underlying SLE warranted administering corticosteroids with subsequent complete resolution of IIH. Pediatricians, neurologists, intensivists, and ophthalmologists should consider SLE as a differential diagnosis in children presenting with IIH.
Subject(s)
Lupus Erythematosus, Systemic , Pseudotumor Cerebri , Humans , Female , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/diagnosis , Child , Pseudotumor Cerebri/diagnosis , Pseudotumor Cerebri/etiology , Diagnosis, Differential , Headache/etiology , Intracranial Hypertension/etiology , Intracranial Hypertension/diagnosisABSTRACT
Introducción: El síndrome de hipertensión intracraneal idiopática o seudotumor cerebri (STC) en niños está en constante revisión, respecto a su definición, etiologías asociadas, diagnóstico y terapéutica más apropiada. Objetivos y métodos: Se revisaron los casos de STC < 15 años de edad en un hospital de referencia en los últimos 12 años. Se estudiaron las características clínico-epidemiológicas y el procedimiento diagnóstico-terapéutico empleado. Se definió STC como presión intracraneal > 25cmH2O por punción lumbar (PL), con estudio de resonancia magnética cerebral sin lesión ocupante de espacio. Resultados: Se registró a 12 niños con STC, media de edad de 10 años, 90% mujeres. Todos presentaban peso normal. El 82% manifestaba síntomas: cefalea (66%), diplopía (8%) o baja visión (8%). Todos asociaban papiledema (17% unilateral). La PL fue diagnóstica en el 100% y la neuroimagen fue normal en el 91%. Se evidenció un posible desencadenante en 5 casos (2 farmacológico y 3 infeccioso por Mycoplasma pneumoniae [M. pneumoniae]). El 91% recibió tratamiento médico: en el 75% consistió en PL repetidas y en el 42% solo acetazolamida y/o prednisona. La evolución fue favorable en todos ellos. Conclusiones: La incidencia de STC fue de aproximadamente 1/100.000 niños/año, similar a estudios previos. En esta población, el sobrepeso no es un factor de riesgo. La infección por M. pneumoniae podría actuar como desencadenante de STC y favorecer recurrencias tardías. La ausencia de síntomas parece independiente del grado de presión intracraneal. El tratamiento con acetazolamida es eficaz en la mayoría de los casos, desterrando el uso de PL repetidas
Introduction: The definition, associated aetiologies, diagnosis, and treatment of idiopathic intracranial hypertension, or pseudotumour cerebri (PTC), are constantly being revised in the paediatric population. Objectives and methods: Our study included children younger than 15 years old with PTC and attended at a reference hospital in the past 12 years. We analysed the clinical and epidemiological features of our sample and the diagnostic and treatment approaches. PTC was defined as presence of intracranial hypertension (CSF opening pressure> 25 cmH2O) and absence of space-occupying lesions in brain MR images. Results: A total of 12 children with PTC were included; mean age was 10 years and 90% were girls. Weight was normal in all patients. Eighty-two percent of the patients had symptoms: headache (66%), diplopia (8%), and visual loss (8%). All of them displayed papilloedema (17% unilaterally). Lumbar puncture (LP) provided the diagnosis in all cases and 91% showed no relevant MRI findings. A potential cause of PTC was identified in 5 cases: pharmacological treatment in 2 and infection (Mycoplasma pneumoniae [M. pneumoniae]) in 3. Ninety-one per cent of the patients received treatment: 75% underwent several LPs and 42% received acetazolamide and/or prednisone. Outcomes were favourable in all cases. Conclusions: The incidence of PTC was estimated at approximately 1 case per 100 000 children/years, in line with data reported by previous studies. Overweight was not found to be a risk factor for PTC in this population. M. pneumoniae infection may trigger PTC and cause recurrences at later stages. The absence of symptoms seems to be independent from the degree of intracranial hypertension. Acetazolamide treatment is effective in most cases, and it represents a viable alternative to repeated LP
Subject(s)
Humans , Male , Female , Child , Adolescent , Pseudotumor Cerebri/diagnosis , Pseudotumor Cerebri/etiology , Acetazolamide/therapeutic use , Disease Progression , Pseudotumor Cerebri/epidemiology , Pseudotumor Cerebri/therapy , Retrospective Studies , Spinal Puncture , Papilledema/complicationsABSTRACT
ABSTRACT Objective: To report cases of children and adolescents diagnosed with pseudotumor cerebri associated or not with rheumatic disease. Methods: This was a retrospective study based on medical reports of 29 patients, up to 18 years of age and diagnosed with pseudotumor cerebri, followed up in the Pediatric Rheumatology and Neurology outpatient clinics of a tertiary hospital, until December 2016. Results: Among the 29 patients diagnosed with pseudotumor cerebri, 51.7% were girls and the mean age at the disease onset was 12.3 years. In 18 patients (62%) where an etiology was found, four were associated with a rheumatic disease. The most common symptom was headache (69%) and acetazolamide was the most used medication (69%). Two patients developed blindness and 10 are still being followed up. Conclusion: Although rare, pseudotumor cerebri should be considered in children with headaches, especially in patients with rheumatic disease.
RESUMO Relatar os casos de crianças e adolescentes com diagnóstico de pseudotumor cerebral com ou sem doença reumática. Métodos: Estudo retrospectivo através de revisão de prontuários, 29 pacientes com idade até 18 anos e diagnóstico de pseudotumor, atendidos nos ambulatórios de Reumatologia Pediátrica e Neurologia de um hospital terciário, registrados até dezembro de 2016. Resultados: Dentre os 29 pacientes com diagnóstico de pseudotumor cerebral, 51,7% eram meninas. A média de idade de aparecimento dos sintomas foi de 12,3 anos. Em relação à etiologia do pseudotumor cerebral, em 18 pacientes (62%) foi possível identificar uma causa, sendo o diagnóstico de doença reumática associada em quatro desses casos. Cefaléia foi o sintoma mais frequente (69%), e a medicação mais utilizada foi a acetazolamida (69%). Dois pacientes evoluíram para cegueira e 10 ainda se encontram em seguimento ambulatorial. Conclusão: Concluímos que, apesar de raro, o diagnóstico de pseudotumor cerebral deve ser considerado em crianças com cefaleia, principalmente nos pacientes com doença reumática.
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Young Adult , Pseudotumor Cerebri/diagnosis , Rheumatic Diseases/diagnosis , Pseudotumor Cerebri/etiology , Pseudotumor Cerebri/drug therapy , Papilledema/etiology , Rheumatic Diseases/complications , Retrospective Studies , Headache/complications , Acetazolamide/therapeutic useABSTRACT
La tortícolis consiste en una postura cefálica anómala con inclinación de la cabeza hacia un lado y rotación del mentón hacia el lado contrario. No es un diagnóstico en sí mismo sino un signo clínico que aparece en patologías de diferente gravedad. La etiología en la edad pediátrica difiere a la edad adulta existiendo un diagnóstico diferencial muy amplio. Presentamos tres casos clínicos atendidos en nuestro servicio con etiologías poco frecuentes y realizamos una revisión de la tortícolis en la edad pediátrica
Torticollis is an anomalous head posture related with the body axis with cervical rotation and contralateral tilt of the head. It ́s not a diagnosis in itself but a clinical sign with a broad differential diagnosis. The aetiology in children differs from adults. We report three cases with non-frequent aetiolo-gies and review literature about this topic in the pediatric age
Subject(s)
Humans , Female , Infant , Child , Torticollis/diagnosis , Joint Dislocations/complications , Atlanto-Axial Joint/injuries , Neck Pain/etiology , Pseudotumor Cerebri/etiology , Headache/etiology , Benign Paroxysmal Positional Vertigo/diagnosis , Acetazolamide/therapeutic use , Sulpiride/therapeutic useABSTRACT
La hipertensión endocraneana idiopàtica se asocia infrecuentemente con la hipovitaminosis A y D. Se presenta el caso de una paciente femenina de 8 años con visión borrosa de 24 horas y papiledema bilateral. Resonancia magnética nuclear normal. Presión de apertura de líquido cefalorraquídeo: 260 mm^O. Presentó déficit de vitamina A y D, e inició un tratamiento sustitutivo. El segundo caso corresponde a un paciente masculino de 12 años con fiebre y odinofagia de 3 días. Con antecedente de glomerulonefritis y sobrepeso. Presentaba edema bipalpebral y papiledema. Tomografia axial computada de la órbita: aumento de líquido en la vaina de ambos nervios ópticos. Resonancia magnética nuclear: aracnoidocele intraselar. Presión de apertura de líquido cefalorraquídeo: 400 mm^O. Presentó déficit de vitamina D y B6, e inició el tratamiento sustitutivo. La elevación de la presión intracraneal desencadena mecanismos de compensación que, al fallar, pueden comprometer la vida o provocar graves discapacidades neurológicas. Reconocer la causa para un enfoque terapéutico preciso es clave para disminuir la morbimortalidad asociada a esta patología.
Idiopathic endocranial hypertension is infrequently associated with hypovitaminosis A and D. The case of an 8-year-old female with 24-hour blurred vision and bilateral papilledema is presented. Nuclear magnetic resonance was normal. Opening pressure of cerebrospinal fluid: 260 mm^O. She presented vitamin A and D deficiency and started replacement therapy. The second case corresponds to a 12-year-old male with fever and odynophagia of 3 days. History of glomerulonephritis and overweight. He had bipalpebral edema and papilledema. Computed tomography scan of the orbit: increase of fluid in the sheath of both optic nerves. Nuclear magnetic resonance: intrasellar arachnoidocele. Opening pressure of cerebrospinal fluid: 400 mmH2O. He presented vitamin D and B6 deficiency and started replacement treatment. The elevation of intracranial pressure triggers compensation mechanisms that, when they fail, can compromise life or cause serious neurological disabilities. Recognizing the cause for an accurate therapeutic approach is key to reduce the morbidity and mortality associated with this pathology.
Subject(s)
Humans , Male , Female , Child , Vitamin B 6 Deficiency/complications , Vitamin A Deficiency/complications , Vitamin D Deficiency/complications , Pseudotumor Cerebri/diagnosis , Vitamin B 6 Deficiency/drug therapy , Vision Disorders/etiology , Vitamin A/administration & dosage , Vitamin A Deficiency/drug therapy , Vitamin D/administration & dosage , Vitamin D Deficiency/drug therapy , Pseudotumor Cerebri/etiology , Magnetic Resonance Imaging , Tomography, X-Ray Computed/methods , Papilledema/etiology , Intracranial Hypertension/diagnosis , Intracranial Hypertension/etiology , Vitamin B 6/administration & dosageABSTRACT
Resumen El lupus eritematoso sistémico es una enfermedad autoinmunitaria crónica que afecta múltiples sistemas orgánicos, incluido el sistema nervioso central. El seudotumor cerebral es un síndrome clínico que se caracteriza por aumento de la presión intracraneal en ausencia de lesiones que ocupen espacio u otra causa detectable, que afecta con frecuencia a mujeres jóvenes y obesas. Se presenta el caso de una mujer con diagnóstico de seudotumor cerebral y lupus eritematoso sistémico diagnosticado de novo durante el embarazo.
Abstract Systemic lupus erythematous is a chronic multi-systemic autoimmune disease that affects multiple organ systems, including the central nervous system. Pseudotumor cerebri is a disorder associated with increased intracranial pressure in the absence of a space-occupying lesion or other identifiable cause that affects young and obese women. We present the case of a pregnant woman with both pseudotumor cerebri and a new diagnosis of active systemic lupus erythematous.
Subject(s)
Female , Humans , Pregnancy , Young Adult , Pregnancy Complications/etiology , Pseudotumor Cerebri/etiology , Lupus Erythematosus, Systemic/complicationsABSTRACT
Pseudotumor cerebri is a relatively common pathology that is characterized by intracranial hypertension in the absence of mass lesions. It commonly affects young and obese women, and its presentation with visual loss and bilateral papilledema is well-described in the literature. We present a case of a 44-year-old, non-obese, female patient presenting with unilateral papilledema and iron-deficiency anemia. This case emphasizes this unusual presentation and the rare association with iron deficiency.
O pseudotumor cerebral é uma patologia relativamente comum, caracterizada pela hipertensão intracraniana na ausência de lesões causando efeito de massa. Frequentemente afeta mulheres jovens e obesas, e sua apresentação, com perda do campo visual e papiledema bilateral, é bem descrita na literatura. Nós apresentamos um caso de uma paciente de 44 anos, não obesa, com papiledema unilateral e anemia ferropriva. Esse caso destaca essa apresentação incomum e a rara associação com a deficiência de ferro.
Subject(s)
Humans , Female , Adult , Pseudotumor Cerebri , Pseudotumor Cerebri/etiology , Papilledema , Anemia, Iron-DeficiencyABSTRACT
ABSTRACT CONTEXT: Pseudotumor cerebri occurs when there is an increase in intracranial pressure without an underlying cause, usually leading to loss of vision. It is most commonly observed in obese women of child-bearing age. CASE REPORT: A 46-year-old woman presented at our service with idiopathic intracranial hypertension that had been diagnosed two years earlier, which had led to chronic refractory headache and an estimated 30% loss of visual acuity, associated with bilateral papilledema. She presented partial improvement of the headache with acetazolamide, but the visual loss persisted. Her intracranial pressure was 34 cmH2O. She presented a body mass index of 39.5 kg/m2, also associated with high blood pressure. Computed tomography of the cranium with endovenous contrast did not show any abnormalities. She underwent Roux-en-Y gastric bypass with uneventful postoperative evolution. One month following surgery, she presented a 24% excess weight loss. An ophthalmological examination revealed absence of visual loss and remission of the papilledema. There were no new episodes of headache following the surgery. There was also complete resolution of high blood pressure. The intracranial pressure decreased to 24 cmH2O, six months after the surgery. CONCLUSION: Although the condition is usually associated with obesity, there are few reports of bariatric surgery among individuals with pseudotumor cerebri. In cases studied previously, there was high prevalence of resolution or improvement of the disease following bariatric surgery. There is no consensus regarding which technique is preferable. Thus, further research is necessary in order to establish a specific algorithm.
RESUMO CONTEXTO: O pseudotumor cerebri ocorre quando há aumento na pressão intracraniana sem causa subjacente, comumente levando a perda visual. É mais comum em mulheres obesas em idade fértil. RELATO DE CASO: Mulher de 46 anos, foi admitida com hipertensão intracraniana idiopática diagnosticada há dois anos, que levou a cefaleia refratária crônica e perda estimada de 30% da acuidade visual, associada a papiledema bilateral. Apresentou melhora parcial da cefaleia com acetazolamida, mas a perda visual persistiu. A pressão intracraniana era de 34 cmH2O. Apresentava índice de massa corpórea de 39,5 kg/m2, associado a hipertensão arterial. Tomografia computadorizada com contraste endovenoso de crânio não apresentou anormalidades. Foi submetida ao bypass gástrico em Y de Roux, com evolução pósoperatória sem intercorrências. Um mês após a cirurgia, apresentou perda de peso em excesso de 24%. Um exame oftalmológico demonstrou ausência de perda visual e remissão do papiledema; não houve novos episódios de cefaleia após a cirurgia. Houve também resolução completa da hipertensão arterial. A pressão intracraniana caiu para 24 cmH2O após seis meses da cirurgia. CONCLUSÃO: Embora a condição seja usualmente associada à obesidade, há escassos relatos de cirurgia bariátrica em indivíduos com pseudotumor cerebri. Nos casos previamente estudados, há alta prevalência de resolução ou de melhora da doença após a cirurgia bariátrica. Não há consenso sobre qual é a técnica cirúrgica de escolha. Portanto, mais estudos são necessários para estabelecer um algoritmo específico.
Subject(s)
Humans , Female , Obesity, Morbid/surgery , Obesity, Morbid/complications , Pseudotumor Cerebri/etiology , Gastric Bypass , Papilledema/etiology , Intracranial Hypertension/etiology , Pseudotumor Cerebri/surgery , Papilledema/surgery , Treatment Outcome , Intracranial Hypertension/surgeryABSTRACT
La hipertensión intracraneal idiopática, también conocida como pseudotumor cerebral, es una enfermedad caracterizada por un incremento de la presión intracraneal no atribuible a masas cerebrales o a alteraciones estructurales focales, con composición normal del líquido cefalorraquídeo. En estudios imagenológicos pueden observarse ventrículos normales o pequeños. Se desconoce su etiología y patogenia. Es causa eludible de pérdida de la visión, tanto en adultos como en niños. El tratamiento es con frecuencia efectivo y la mayoría de los pacientes experimentan una resolución completa de los síntomas sin persistencia de déficits.(AU)
Idiopathic intracranial hypertension, also known as pseudotumor cerebri is a condition characterized by increased intracranial pressure, not caused to mass lesions or focal structural abnormalities, or with normal composition of the cerebrospinal fluid. Ventricles can be observed normal or small in imaging studies. Its etiology and pathogenesis are unknown. Idiopathic intracranial hypertension is an avoidable cause of visual loss, in both adults and children. Treatment is usually effective, and most patients have observed complete resolution of symptoms without persistent deficits.(AU)
Subject(s)
Humans , Male , Female , Adult , Pseudotumor Cerebri/diagnosis , Pseudotumor Cerebri/epidemiology , Pseudotumor Cerebri/etiology , Pseudotumor Cerebri/physiopathology , Pseudotumor Cerebri/therapyABSTRACT
No disponible
Subject(s)
Humans , Female , Adult , Pseudotumor Cerebri/etiology , Hypoparathyroidism/complications , Spinal PunctureABSTRACT
Mild head injury has been described as rare cause of idiopathic intracranial hypertension (IIH). In the presence of IIH, initial treatment is clinical and surgical treatment, such as lumboperitoneal shunt. Most cases have a good prognosis. The patient have 9-year-old male, went to the emergency room with a history of accidental fall, presenting headache, vomiting and blurred vision. Physical examination showed good overall condition. Neurological examination: normal. Fundoscopy: incipient bilateral papilledema. Normal cranial CT. The general picture suggested by exclusion of other causes IIH diagnosis. He underwent symptomatic treatment with acetazolamide, painkillers and rest. Discharged from the hospital on the eighth hospital day with no complaints being referred for outpatient treatment.
O traumatismo cranioencefálico leve tem sido uma causa rara de hipertensão intracraniana idiopática (HII). Na presença de HII, o tratamento inicial é clínico e o tratamento cirúrgico é feito por meio da derivação lumboperitoneal. A maioria dos casos cursa com bom prognóstico. Um paciente com 9 anos de idade, masculino, foi admitido na emergência com história de queda acidental, apresentava cefaleia, vômitos e visão turva. Ao exame físico apresentou bom estado geral. Exame neurológico: normal; fundoscopia: papiledema bilateral incipiente; TC do crânio normal. O quadro sugeriu o diagnóstico de HII, por exclusão de outras causas. Foi submetido a tratamento sintomático com acetazolamida, analgésicos e repouso. Recebeu alta médica hospitalar no oitavo dia, sem queixas, sendo encaminhado para acompanhamento ambulatorial.
Subject(s)
Humans , Male , Pseudotumor Cerebri/etiology , Pseudotumor Cerebri/therapy , Papilledema , Craniocerebral Trauma/complicationsABSTRACT
Patients with hydrocephalus and risk factors for overdrainage may be submitted to ventricular shunt (VS) implant with antisiphon device. The objective of this study was to prospectively evaluate for two years the clinical and tomographic results of the implant of fixed-pressure valves with antisiphon device SPHERA® in 35 adult patients, with hydrocephalus and risk factors for overdrainage. Of these, 3 had congenital hydrocephalus in adult patients with very dilated ventricles (Evans index >50%), 3 had symptomatic overdrainage after previous VS implant (subdural hematoma, hygroma or slit ventricle syndrome), 1 had previous chronic subdural hematoma, 15 had normal pressure hydrocephalus with final lumbar pressure <5 cm H2O after tap test (40 mL), 6 had pseudotumor cerebri, and 7 had hydrocephalus due to other causes. Clinical improvement was observed and sustained in 94.3% of the patients during the two-year period with no computed tomography (CT) evidence of hypo or overdrainage, and no immediate early or late significant complications.
Pacientes com hidrocefalia e fatores de risco para hiperdrenagem podem ser submetidos ao implante de derivação ventricular (VS) com mecanismo antissifão. O objetivo deste trabalho foi avaliar prospectivamente os resultados clínicos e tomográficos do implante de válvulas de pressão fixa com antissifão SPHERA® em 35 pacientes adultos, com hidrocefalia e risco de hiperdrenagem, acompanhados por dois anos. Destes, 3 apresentavam hidrocefalia congênita em adulto, com ventrículos muito dilatados (índice de Evans >50%); 3 tinham hiperdrenagem sintomática pós-derivação ventricular prévia (hematoma subdural, higroma ou síndrome dos ventrículos colabados; 1 apresentava hematoma subdural crônico pregresso; 15 apresentavam hidrocefalia de pressão normal com pressão lombar final <5 cm H2O após tap test (40 mL); 6 apresentavam pseudotumor cerebral; e 7, devido a outras causas. A melhoria clínica foi detectada e sustentada em 94,3% dos pacientes no período de dois anos, sem indícios tomográficos de hipo ou hiperdrenagem e sem complicações significativas imediatas, precoces ou tardias.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Cerebrospinal Fluid Shunts/instrumentation , Drainage/instrumentation , Hydrocephalus/surgery , Hydrostatic Pressure/adverse effects , Cerebrospinal Fluid Pressure/physiology , Cerebrospinal Fluid Shunts/adverse effects , Equipment Design , Hematoma, Subdural/etiology , Hydrocephalus, Normal Pressure/physiopathology , Hydrocephalus, Normal Pressure/surgery , Hydrocephalus/physiopathology , Prospective Studies , Pseudotumor Cerebri/etiology , Slit Ventricle Syndrome/etiology , Tomography, X-Ray ComputedABSTRACT
The classical manifestations of Behçet disease are mouth ana genital ulcers, cutaneous lesions ana ocular involvement. The central nervous system is affected in 5 to 59 percent of the cases, usually in the form of meningoencephalitis or sinus venous thrombosis. We report a 17-year-old femóle presenting with a two weeks history of progressive headache, nausea and blurred vision. An initial magnetic resonance was normal. Fifteen days later she was admitted to the hospital due to progression of visual impairment. Shegave a history of oral ulcers and arthralgias. A new magnetic resonance was normal. A lumbar puncture showed a cerebrospinal fluid with a protein concentration of 14 mg/dl, aglucose concentration of 64 mg/dl, 20fresh red blood cells and a pressure of 26 cm H(2)0. The diagnosis of a pseudotumor cerebri, secondary to Behçet disease was raised and the patient was treated with colchicine and acetazolamide. The evolution was torpid and an anterior uveitis was alsofound. After discharge, she continued with oral and genital ulcers and was treated with infliximab. Despite treatment, headache persists.
Subject(s)
Adolescent , Female , Humans , Behcet Syndrome/complications , Pseudotumor Cerebri/etiology , Acetazolamide/therapeutic use , Behcet Syndrome/diagnosis , Behcet Syndrome/drug therapy , Colchicine/therapeutic use , Pseudotumor Cerebri/diagnosis , Pseudotumor Cerebri/drug therapyABSTRACT
No disponible
Subject(s)
Humans , Male , Child, Preschool , Sphenoid Sinusitis/complications , Pseudotumor Cerebri/etiology , Intracranial Hypertension/complicationsABSTRACT
O pseudotumor cerebral é uma síndrome neurológica relativamente comum na adolescência. Na maioria dos casos, a etiologia é idiopática, mas pode haver complicações graves, como cegueira, relacionadas com a hipertensão intracraniana. O objetivo deste artigo é enfatizar o diagnóstico diferencial do pseudotumor cerebral, com atenção especial às etiologias tratáveis. Relatamos o caso de um adolescente de 12 anos que se apresentou com diplopia e cefaléia 9 dias após otite média e mastoidite à direita. A tomografia computadorizada do crânio foi normal, mas a ressonância magnética do encéfalo detectou trombose dos seios transverso e sigmóideo ipsilaterais, a qual respondeu à anticoagulação precoce. A conclusão é que a ressonância magnética do encéfalo é essencial nos pacientes com diagnóstico clínico de pseudotumor cerebral para exclusão de causas tratáveis, como a trombose venosa dural.