Subject(s)
Brain Diseases/microbiology , Diabetes Complications , Mucormycosis/diagnosis , Nose Diseases/microbiology , Orbital Diseases/microbiology , Antifungal Agents/therapeutic use , Brain Diseases/diagnostic imaging , Brain Diseases/therapy , Debridement , Female , Humans , Magnetic Resonance Imaging , Middle Aged , Mucormycosis/therapy , Nose Diseases/diagnostic imaging , Nose Diseases/therapy , Orbit/diagnostic imaging , Orbit/microbiology , Orbital Diseases/diagnostic imaging , Orbital Diseases/therapy , Pterygopalatine Fossa/diagnostic imaging , Pterygopalatine Fossa/microbiologyABSTRACT
La mucormicosis es una infección rara y oportunista. El objetivo del estudio fue revisar los casos presentados en nuestro servicio con mucormicosis rino-orbitaria y describir el protocolo clínico, diagnóstico y terapéutico empleado en estos pacientes. Se realizó un estudio retrospectivo, longitudinal, descriptivo, en el que se evaluaron expedientes de pacientes con mucormicosis rino-orbitaria del periodo de enero a octubre de 2013. Se encontraron 5 casos, con afección de fosa pterigomaxilar en el 100% de nuestros pacientes. Se realizó tratamiento médico y quirúrgico temprano mediante desbridamiento extenso endoscópico (incluyendo desbridamiento y resección de fosa pterigomaxilar) y exenteración orbitaria a los pacientes que se presentaron con síndrome de ápex orbitario en conjunto con el servicio de oftalmología de nuestro hospital, obteniendo excelentes resultados en la supervivencia (100% de supervivencia) (AU)
Mucormycosis is a rare opportunistic infection. The aim of the study was to review the cases presented in our department with rhino-orbital mucormycosis and to describe the clinical protocol, diagnosis and therapy used in these patients. We conducted a retrospective, longitudinal, descriptive study, in which we evaluated the records of patients with rhino-orbital mucormycosis in the period from January to October 2013. We found 5 cases. Pterigomaxillary fossa disease was found in 100% of our patients. Medical and surgical treatment perfor0med early by extensive endoscopic debridement (including debridement and resection of pterygomaxillary fossa) and orbital exenteration in patients presenting with orbitary apex syndrome in conjunction with the ophthalmology department of our hospital, with excellent results in the survival of our patients (all patients survived) (AU)
Subject(s)
Humans , Mucormycosis/therapy , Sinusitis/microbiology , Central Nervous System Infections/prevention & control , Fungemia/prevention & control , Opportunistic Infections/epidemiology , Retrospective Studies , Pterygopalatine Fossa/microbiology , Debridement , Diabetes Complications/epidemiologyABSTRACT
Aspergillosis of the central nervous system (CNS) is an uncommon infection, mainly found in immunocompromised patients but rarely seen among immunocompetent patients. Herein we describe a 57 year-old immunocompetent man who suffered intracranial aspergillosis spread by the pterygopalatine fossa (PPF) following a tooth extraction. Based on magnetic resonance imaging (MRI) characteristics, in this report we focus on the spreading routes of CNS aspergillosis via communicative structures of the PPF, the relationship between clinical manifestations and the locations of the lesion, and propose a therapeutic strategy to improve the prognosis.
Subject(s)
Brain Diseases/microbiology , Immunocompetence , Neuroaspergillosis/microbiology , Pterygopalatine Fossa/microbiology , Brain Diseases/diagnosis , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Neuroaspergillosis/diagnosis , Tooth Extraction/adverse effectsABSTRACT
Aspergillosis of the central nervous system (CNS) is an uncommon infection, mainly found in immunocompromised patients but rarely seen among immunocompetent patients. Herein we describe a 57 year-old immunocompetent man who suffered intracranial aspergillosis spread by the pterygopalatine fossa (PPF) following a tooth extraction. Based on magnetic resonance imaging (MRI) characteristics, in this report we focus on the spreading routes of CNS aspergillosis via communicative structures of the PPF, the relationship between clinical manifestations and the locations of the lesion, and propose a therapeutic strategy to improve the prognosis.
