English Translation of M. Bérard: Tumeur Embryonnaire Du Muscle Strié. [Embryonal Tumor of Striated Muscle]. Lyon Med 1894; 77: 52.

We have chosen to translate what we believe to be the first publication of a well-documented case of a young patient with embryonal rhabdomyosarcoma. The author, M. Léon Bérard, was a hospital fellow working in the department of M. Vincent at the Charité Hospital. The document was presented to La Société des Sciences médicales de Lyon (The Society of Medical Sciences of Lyon, France), in July,1894. The translation follows below.

Early history of pathology studies by the Intergroup Rhabdomyosarcoma Study Group.

This review chronicles the series of publications that were the result of the willingness of pathologists and clinicians in the United States to share their pathologic materials and clinical data on patients who were placed on treatment protocols for rhabdomyosarcoma and related tumors over an extended period of time. The availability of this database enabled pathologists and clinicians to study a tumor type that is rare in individual institutions, but occurs in large enough numbers to produce valid conclusions not otherwise possible. Furthermore, young investigators were challenged by this opportunity and were able to spend the necessary time to make new observations that, in retrospect, helped direct protocol designs that produced significant improvement in patient survival. The key factor in this process is the surrender of individual scientific prerogatives to a small number of investigators. It is also important to recognize that the pathologist component of these series of contributions is only a part of the entire effort. It takes an organization of gifted, dedicated experts in many disciplines working together. The investigators who served on the Intergroup Rhabdomyosarcoma Group over a 25-year period eminently fulfilled this.

Rabdomiossarcoma ocular: estudo clínico de 12 casos / Ocular rabdomiossarcoma: clinical study of 12 cases

Foram avaliados 12 pacientes com rabdomiossarcoma ocular em relaç*o aos seguintes dados: sexo, idade, raça, tempo de história, localizaçäo do tumor, exame ocular e estudo anatomopatológico. Os resultados mostraram-se concordantes com a literatura. 8 casos tiveram um seguimento adequado tendo sido analisados em relaçäo ao tratamento, evoluçäo e complicaçöes. Os 2 pacientes que foram a óbito tinham sido submetidos a radioterapia isoladamente. A paciente que recebeu radioterapia e quimioterapia associada a exenteraçäo respondeu bem à terapêutica e pode ser considerada curada. Os demais pacientes foram tratados com quimioterapia e radioterapia, näo tendo apresentado recorrências até o momento, sendo que os autores concluem ser este o melhor esquema terapêutico

Rabdomiosarcoma infantil / Childhood rhabdomyosarcoma

Se realiza un estudio prospectivo de 85 pacientes menores de 15 años con Sarcoma de partes blandas vistos en el Instituto Nacional de Enfermedades Neoplásicas entre Enero 1980 y Diciembre 1986. Se constata que el Rabdomiosarcoma es el tumor mas frecuente en los menores de 15 años y el Fibrohistiocitoma Maligno es el tumor más frecuente en los mayores de 15 años. De los 56 niñs con Rabdomiosarcoma, 44 eran de tipo Embrionario, 6 Mixtos, 5 Alveolar y 1 Pleomórfico. Las localizaciones más frecuentes fueron la de la cabeza y el cuello en 40%, las extremidades en.25% y la genitourinaria en 14%, siendo el 82% de los pacientes portadores de enfermedad avanzada (Estadios III-IV). Con el tratamiento multidisciplinario, combinado cirugía, quimio y radioterapia se obtiene una sobrevida libre de enfermedad del 100% para el estadío I,83.3% para el estadío II, y 22.7% para la localización y el estadío clínico; además se hace énfasis en la importancia del seguimiento para detectar recurrencias, efectos secundarios y/o neoplasias secundarias