Subject(s)
Acquired Immunodeficiency Syndrome/epidemiology , Bacterial Infections/epidemiology , Parasitic Diseases/epidemiology , Acquired Immunodeficiency Syndrome/transmission , Bacterial Infections/transmission , Ethnicity , Humans , Italy , Parasitic Diseases/transmission , Sarcoma, Kaposi/epidemiology , Sarcoma, Kaposi/transmission , TravelSubject(s)
Cytomegalovirus Infections/transmission , Homosexuality , Sarcoma, Kaposi/transmission , Acquired Immunodeficiency Syndrome/immunology , Antibodies, Viral/immunology , Cross-Sectional Studies , Cytomegalovirus/immunology , Cytomegalovirus Infections/epidemiology , Cytomegalovirus Infections/immunology , Female , Humans , Male , Prospective Studies , Sarcoma, Kaposi/epidemiology , Sarcoma, Kaposi/immunology , United StatesSubject(s)
Homosexuality , Sarcoma, Kaposi/etiology , Skin Neoplasms/etiology , Adult , Biopsy , Cytomegalovirus , Cytomegalovirus Infections/complications , Humans , Male , Middle Aged , Mucous Membrane , Neoplasm Staging , Pneumonia, Pneumocystis/complications , Risk , Sarcoma, Kaposi/transmission , Skin Neoplasms/transmissionSubject(s)
Disease Outbreaks , Homosexuality , Immunologic Deficiency Syndromes/epidemiology , Sarcoma, Kaposi/epidemiology , Adult , Cytomegalovirus Infections/etiology , Female , Humans , Immunologic Deficiency Syndromes/etiology , Immunologic Deficiency Syndromes/transmission , Immunosuppressive Agents/adverse effects , Male , Pneumonia, Pneumocystis/etiology , Risk , Sarcoma, Kaposi/etiology , Sarcoma, Kaposi/transmissionABSTRACT
The clinical findings in eight young homosexual men in New York with Kaposi's sarcoma showed some unusual features. Unlike the form usually seen in North America and Europe, it affected younger men (4th decade rather than 7th decade); the skin lesions wee generalised rather than being predominantly in the lower limbs, and the disease was more aggressive (survival of less than 20 months rather 8-13 years). All eight had had a variety of sexually transmitted diseases. All those tested for cytomegalovirus antibodies and hepatitis B surface antigen of anti-hepatitis B antibody gave positive results. This unusual occurrence of Kaposi's sarcoma in a population much exposed to sexually transmissible diseases suggests that such exposure may play a role in its pathogenesis.
