Subject(s)
Alopecia/virology , COVID-19/complications , Scalp Dermatoses/virology , Aged , Alopecia/complications , Female , Humans , Male , Middle Aged , SARS-CoV-2Subject(s)
Dapsone/therapeutic use , Glucocorticoids/therapeutic use , Herpes Zoster/complications , Prednisolone/therapeutic use , Pyoderma Gangrenosum/virology , Scalp Dermatoses/virology , Aged , Anti-Infective Agents/therapeutic use , Drug Therapy, Combination , Humans , Male , Pyoderma Gangrenosum/drug therapy , Pyoderma Gangrenosum/pathology , Scalp Dermatoses/drug therapy , Scalp Dermatoses/pathologyABSTRACT
Human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis (ID) is a chronic, severe and recurrent eczema occurring during childhood in patients vertically infected with HTLV-1. HTLV-1-associated myelopathy/tropical spastic paraparesia (HAM/ TSP) is slow and progressive. We report the case of an adolescent female from a non-endemic area for HTLV-1 who presents ID and, most likely, associated HAM/TSP.
Subject(s)
Dermatitis/virology , HTLV-I Infections/complications , Paraparesis, Tropical Spastic/virology , Skin Diseases, Viral/virology , Adolescent , Dermatitis/pathology , Disease Progression , Female , HTLV-I Infections/pathology , Humans , Immunohistochemistry , Paraparesis, Tropical Spastic/pathology , Scalp Dermatoses/pathology , Scalp Dermatoses/virology , Skin Diseases, Viral/pathologyABSTRACT
Human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis (ID) is a chronic, severe and recurrent eczema occurring during childhood in patients vertically infected with HTLV-1. HTLV-1-associated myelopathy/tropical spastic paraparesia (HAM/ TSP) is slow and progressive. We report the case of an adolescent female from a non-endemic area for HTLV-1 who presents ID and, most likely, associated HAM/TSP.
.Subject(s)
Adolescent , Female , Humans , Dermatitis/virology , HTLV-I Infections/complications , Paraparesis, Tropical Spastic/virology , Skin Diseases, Viral/virology , Disease Progression , Dermatitis/pathology , HTLV-I Infections/pathology , Immunohistochemistry , Paraparesis, Tropical Spastic/pathology , Scalp Dermatoses/pathology , Scalp Dermatoses/virology , Skin Diseases, Viral/pathologySubject(s)
Hand, Foot and Mouth Disease/pathology , Scalp Dermatoses/pathology , Skin/pathology , Adult , Biopsy , Enterovirus/genetics , Female , Hand, Foot and Mouth Disease/virology , Humans , Male , Middle Aged , RNA, Viral/isolation & purification , Reverse Transcriptase Polymerase Chain Reaction , Scalp , Scalp Dermatoses/virology , Sequence Analysis, RNA , Skin/virologyABSTRACT
Cutaneous warts are caused by human papillomavirus (HPV). Prevalence studies of the types of HPV present in cutaneous warts have been carried out more frequently in immunosuppressed patients. The present study was designed to study the association of high-risk HPV in cutaneous warts of immunocompetent patients. A total of 45 cases of cutaneous warts from various sites in immunocompetent subjects were analyzed for HPV. Samples included both archival material i.e., paraffin embedded and fresh tissue. Highly sensitive and comprehensive polymerase chain reaction (PCR) methodology for detection of HPV of high oncogenic potential, HPV 16/18, was employed. Human papillomavirus 16 was detected in 3 (6.6%) patients. None of the lesions demonstrated HPV 18. None of the cutaneous warts demonstrated histopathological features associated with dysplasia or neoplasia. The identification of HPV 16 in cutaneous warts, which are benign proliferations of the skin, further expands the spectrum of HPV-linked lesions. It remains of critical interest to determine whether these types are specifically associated with the development of malignant lesions analogous to those seen in anogenital cancer.
Subject(s)
Facial Dermatoses/virology , Foot Dermatoses/virology , Hand Dermatoses/virology , Human papillomavirus 16/isolation & purification , Human papillomavirus 18/isolation & purification , Papillomavirus Infections/virology , Polymerase Chain Reaction , Scalp Dermatoses/virology , Warts/virology , Abdominal Wall/virology , Adolescent , Adult , Aged , Arm/virology , DNA Probes, HPV , DNA, Viral/analysis , Facial Dermatoses/epidemiology , Female , Foot Dermatoses/epidemiology , Hand Dermatoses/epidemiology , Human papillomavirus 16/genetics , Human papillomavirus 16/pathogenicity , Human papillomavirus 18/genetics , Human papillomavirus 18/pathogenicity , Humans , Immunocompetence , India/epidemiology , Male , Middle Aged , Papillomavirus Infections/epidemiology , Scalp Dermatoses/epidemiology , Thoracic Wall/virology , Warts/epidemiologyABSTRACT
This report describes a clinical case of feline infectious peritonitis (FIP) with multisystemic involvement, including multiple nodular cutaneous lesions, in a cat that was co-infected with feline coronavirus and feline immunodeficiency virus. The skin lesions were caused by a pyogranulomatous-necrotising dermal phlebitis and periphlebitis. Immunohistology demonstrated the presence of coronavirus antigen in macrophages within these lesions. The pathogenesis of FIP involves a viral associated, disseminated phlebitis and periphlebitis which can arise at many sites. Target organs frequently include the eyes, abdominal organs, pleural and peritoneal membranes, and central nervous tissues, but cutaneous lesions have not previously been reported.
Subject(s)
Cat Diseases , Coronavirus Infections/veterinary , Feline Infectious Peritonitis/diagnosis , Feline Infectious Peritonitis/virology , Immunodeficiency Virus, Feline/immunology , Scalp Dermatoses/veterinary , Animals , Antibodies, Viral/analysis , Antibody Formation , Antigens, Viral/analysis , Cat Diseases/diagnosis , Cat Diseases/virology , Cats , Coronavirus Infections/diagnosis , Coronavirus, Feline/isolation & purification , Female , Leukocytes/immunology , Scalp Dermatoses/diagnosis , Scalp Dermatoses/virologyABSTRACT
We report the case of a 70-year-old man with a 1 year history of relapsing folliculitis of the scalp. Bacteriological, mycological and the Tzanck tests from the lesions were negative. Histopathological study showed suppurative perifollicular flogosis. Virological cultures were negative, while HSV nested polymerase chain reaction (nPCR) assays made on swabs and histological sections from the scalp lesions demonstrated the presence of herpes simplex virus type-2 (HSV-2) in all samples. Skin swabs of healthy areas yielded negative results for HSV-2 infection. The folliculitis showed a marked and quick improvement after therapy with famciclovir suggesting a possible etiologic role of HSV-2 in the scalp folliculitis.
Subject(s)
Folliculitis/virology , Herpes Simplex/virology , Scalp Dermatoses/virology , Aged , Herpesvirus 2, Human/genetics , Herpesvirus 2, Human/isolation & purification , Humans , Male , Polymerase Chain ReactionABSTRACT
A series of five patients presented with eruptions beginning on the face. In each case the facial changes were characterized by urticated erythema with minimal epidermal change. The patients also demonstrated more widespread vesiculopapular, macular or purpuric eruptions. At presentation most patients were asymptomatic; however, several subsequently developed constitutional symptoms. Each of these patients was reactive for Barmah Forest virus immunoglobulin (Ig)M, and on repeat testing four were reactive for Barmah Forest virus IgG.
Subject(s)
Alphavirus Infections/diagnosis , Exanthema/virology , Facial Dermatoses/virology , Adult , Alphavirus/isolation & purification , Erythema/virology , Female , Humans , Male , Middle Aged , Pruritus/virology , Scalp Dermatoses/virologySubject(s)
Head and Neck Neoplasms/secondary , Herpes Zoster/diagnosis , Melanoma/secondary , Scalp Dermatoses/diagnosis , Skin Neoplasms/secondary , Acyclovir/therapeutic use , Aged , Antiviral Agents/therapeutic use , Diagnosis, Differential , Head and Neck Neoplasms/diagnosis , Herpes Zoster/drug therapy , Humans , Male , Melanoma/diagnosis , Pruritus/etiology , Pruritus/virology , Scalp Dermatoses/virology , Skin Neoplasms/diagnosisABSTRACT
Hepatitis C virus (HCV) is a common cause of chronic hepatitis and is frequently associated with extrahepatic disease. Recently, cutaneous disorders have been a presenting manifestation of HCV infection. Porphyria cutanea tarda (PCT) is one of the cutaneous diseases associated with hepatitis C. PCT manifests in an acute form with tense bullae and erosions and in a chronic form with milia, scarring, and sclerodermatous changes. HCV has also been implicated as a cause of vasculitis through immune complex deposition. We report a patient in whom HCV was associated with sclerodermoid PCT and a medium vessel vasculitis. This case underscores the importance of HCV and its potential cutaneous manifestations, as well as the importance of recognizing cutaneous manifestations of internal disease that may be the first clue to diagnosis of HCV.