Subject(s)
Blepharitis/microbiology , Pyoderma/pathology , Skin Diseases, Bacterial/pathology , Stomatitis/pathology , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Antiviral Agents/therapeutic use , Blepharitis/diagnosis , Blepharitis/etiology , Blepharitis/pathology , Crohn Disease/complications , Diagnosis, Differential , Female , Glucocorticoids/administration & dosage , Glucocorticoids/therapeutic use , Herpes Simplex/genetics , Humans , Middle Aged , Mouth Mucosa/pathology , Mouth Mucosa/virology , Pyoderma/microbiology , Salmonella/genetics , Salmonella/isolation & purification , Skin Diseases, Bacterial/complications , Skin Diseases, Bacterial/microbiology , Skin Diseases, Bacterial/virology , Stomatitis/diagnosis , Stomatitis/virology , Treatment OutcomeABSTRACT
BACKGROUND: Owing to similar clinical presentations, as of cutaneous disease of different etiologies, and extreme rarity in the global incidence; primary cutaneous actinomycosis often remains as diagnostic challenges. CASE PRESENTATION: Herein, we describe a case of primary cutaneous actinomycosis, erroneously treated as cutaneous tuberculosis, in a patient living with AIDS. On clinical examination, the characteristic lesion, resembling cutaneous tuberculosis, observed on the dorsum of a left leg. No other lesion elsewhere on the body was observed, however. Cytological examinations of the stabbed biopsy were negative for malignant cells; although hyper-keratosis and mild-acanthosis of epidermis, acute inflammatory infiltrates comprising plasma cell, macrophages and neutrophils were observed in the upper and mid dermis. The pus aspirated from lesion grew a molar tooth, adherent colonies in microaerophilic condition. Further, identifications and susceptibility pattern against recommended antibiotics were assessed as per the CLSI (Clinical and Laboratory Standard Institute) guidelines. Subsequently, the case was then, diagnosed as primary cutaneous actinomycosis. Radiographic imaging of abdomen and lungs were normal; no feature of disseminated actinomycosis seen. Penicillin G followed by Penicillin V, was prescribed for 12 months. The patient underwent progressive changes and no relapse noted on periodic follow-up. CONCLUSION: The case underscores cutaneous actinomycosis requires a diagnosis consideration, especially in People Living with HIV/AIDS (PLHA), where myriad of opportunistic cutaneous infections are common.
Subject(s)
Actinomycosis/diagnosis , HIV Infections/complications , Skin Diseases, Bacterial/diagnosis , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/microbiology , Actinomyces/drug effects , Actinomycosis/drug therapy , Actinomycosis/virology , Adult , Anti-Bacterial Agents/therapeutic use , Biopsy , Foot/microbiology , HIV Infections/microbiology , Humans , Male , Skin/microbiology , Skin/pathology , Skin Diseases, Bacterial/drug therapy , Skin Diseases, Bacterial/virologySubject(s)
AIDS-Related Opportunistic Infections/diagnosis , Abscess/diagnosis , Acquired Immunodeficiency Syndrome/complications , Actinomycetales Infections/diagnosis , Rhodococcus equi , Skin Diseases, Bacterial/diagnosis , Abscess/pathology , Abscess/virology , Actinomycetales Infections/pathology , Actinomycetales Infections/virology , Female , Humans , Middle Aged , Scalp/microbiology , Scalp/pathology , Skin/microbiology , Skin/pathology , Skin Diseases, Bacterial/pathology , Skin Diseases, Bacterial/virologyABSTRACT
Paediatric patients hospitalised with varicella (n = 1575) were reported to a French national network between March 2003 and July 2005. Superinfection was identified in 50.3% of cases, principally of skin and soft-tissue (36.5%). The risk of superinfection increased with fever relapse, use of non-steroidal anti-inflammatory drugs, prolonged fever, an age of 1-5 years, and contamination at the childminder's home. Neurological complications were observed in 7.8% of cases, while pulmonary complications were less frequent (3.1%). Forty-nine patients had sequelae and eight patients died. Surveillance should continue in France with a view to the future implementation of a universal vaccination programme.
Subject(s)
Chickenpox/epidemiology , Child, Hospitalized/statistics & numerical data , Skin Diseases, Bacterial/epidemiology , Superinfection/epidemiology , Adrenal Cortex Hormones/adverse effects , Age Factors , Chickenpox/complications , Chickenpox/immunology , Child, Preschool , Female , France/epidemiology , Health Surveys , Hospitalization , Humans , Infant , Infant, Newborn , Male , Odds Ratio , Population Surveillance , Risk Factors , Skin Diseases, Bacterial/virology , Superinfection/microbiologySubject(s)
AIDS-Related Opportunistic Infections , Anti-HIV Agents/adverse effects , Drug Eruptions/etiology , Skin Diseases/virology , AIDS-Related Opportunistic Infections/diagnosis , AIDS-Related Opportunistic Infections/therapy , Dermatomycoses/diagnosis , Dermatomycoses/therapy , Dermatomycoses/virology , Humans , Skin Diseases/diagnosis , Skin Diseases/therapy , Skin Diseases, Bacterial/diagnosis , Skin Diseases, Bacterial/therapy , Skin Diseases, Bacterial/virology , Skin Diseases, Viral/diagnosis , Skin Diseases, Viral/therapy , Skin Diseases, Viral/virologyABSTRACT
OBJECTIVE: The aim was an analysis of causes of varicella complications in children hospitalized in the Department if Infectious Diseases In Childhood of Medical University in Warsaw. METHODS AND MAIN OBSERVATIONS: 105 children from 15 day to 15 years of age was observed. 58.1% were male. The median age was 5,8 years. RESULTS AND CONCLUSIONS: Bacterial skin infections and neurological complications were the most frequent complications. Sepsis was diagnosed in 3 children. Vaccination program against varicella can reduce the risk of very severe complications.
