Subject(s)
Crohn Disease/drug therapy , Crohn Disease/microbiology , Intestines/microbiology , Intestines/pathology , Spirochaetales Infections/complications , Tumor Necrosis Factor-alpha/antagonists & inhibitors , Adult , Azathioprine/pharmacology , Azathioprine/therapeutic use , Colonoscopy , Female , Humans , Infliximab/pharmacology , Infliximab/therapeutic use , Intestines/drug effectsABSTRACT
A case of intestinal spirochetosis in a 62-year-old white male is reported. The condition was characterized by chronic flatulence and episodes of intestinal hemorrhage, in addition to the evidence of hypotonic diverticular disease, with a large number of slender organisms in the colon epithelium and cryptae. Spirochetes were demonstrated by Whartin-Starry stain. The serologic tests for syphilis and HIV were positive. Spirochetosis was treated with penicillin G, and the patient remains free of intestinal complaints 20 months later.
Subject(s)
Diverticulosis, Colonic/complications , Gastrointestinal Hemorrhage/etiology , Spirochaetales Infections/complications , Anti-Bacterial Agents/therapeutic use , Diverticulosis, Colonic/diagnosis , Diverticulosis, Colonic/drug therapy , HIV Infections/complications , Humans , Intestinal Mucosa/microbiology , Intestinal Mucosa/pathology , Male , Middle Aged , Penicillin G/therapeutic use , Spirochaetales/isolation & purification , Spirochaetales Infections/diagnosis , Spirochaetales Infections/drug therapyABSTRACT
Um caso de espiroquetose intestinal é relatado em um homem branco de 62 anos. A condição foi caracterizada por flatulência crônica e episódios de hemorragia intestinal, além da evidência de doença diverticular hipotônica dos cólons, com numerosos organismos filamentosos no epitélio e nas criptas do cólon. Os espiroquetas foram demonstrados pela coloração de Whartin-Starry. Os testes sorológicos para sífilis e HIV foram positivos. A espiroquetose foi tratada com penicilina G e o paciente permanece sem queixas intestinais após 20 meses.