ABSTRACT
Introducción: La infestación por Strongyloides stercoralis es más prevalente en regiones tropicales, pero existen casos autóctonos en España, principalmente en La Safor (Valencia). Nuestro objetivo era estudiar los casos de un hospital de la provincia de Alicante y conocer si existían casos autóctonos. Procedimiento: Estudio retrospectivo de los casos diagnosticados de estrongiloidiasis en el Hospital Vega Baja (Orihuela, Alicante) entre enero de 1999 y marzo de 2016. Resultados: Se registraron 10 casos, 4 de ellos autóctonos, presentando 2 de ellos un cuadro de hiperinfestación con desenlace fatal. Todos los casos autóctonos fueron en personas ≥69años con síntomas digestivos, cutáneos y/o respiratorios. La serología fue positiva en los 8casos en los que se realizó. En 3 casos se visualizaron larvas en el estudio histopatológico. Conclusiones: Comunicamos los primeros casos autóctonos de estrongiloidiasis en la región Vega Baja. Se deben implantar programas de cribado principalmente en pacientes inmunosuprimidos o en tratamiento corticoideo (AU)
Introduction: Strongyloides stercoralis infection is more prevalent in tropical regions but autochthonous cases have been reported in Spain, mainly in La Safor (Valencia). The objective is to describe the strongyloidiasis cases registered in a regional hospital of Alicante province (Spain) and to determine if they were autochthonous cases. Methods: Retrospective study of all diagnosed cases of strongyloidiasis in Vega Baja Hospital (Orihuela, Alicante) between January 1999 and March 2016. Results: A total of 10 cases were found, four of which were autochthonous cases. Two of them presented with a hyper-infection syndrome, with a fatal outcome. All autochthonous cases were in patients ≥69years old with gastrointestinal, cutaneous, and/or respiratory symptoms. Serology was positive in the 8 cases studied. Larvae were found in histopathological samples of the gastrointestinal tract of three patients. Conclusions: We communicate the first autochthonous cases of strongyloidiasis in the region of Vega Baja. Screening programs should be implemented, especially in immunosuppressed patients or patients under chronic corticosteroid treatment (AU)
Subject(s)
Humans , Strongyloides stercoralis/isolation & purification , Strongyloidiasis/diagnosis , Strongyloidiasis/microbiology , Biopsy , Risk Factors , Immunosuppression Therapy/methods , Strongyloides stercoralis/microbiology , Strongyloidiasis/pathology , Mass Screening/methods , Retrospective Studies , Enzyme-Linked Immunosorbent Assay/methods , Feces/microbiology , Feces/parasitology , Eosinophilia/microbiology , Colon/pathologyABSTRACT
No disponible
Subject(s)
Humans , Female , Aged , Strongyloidiasis/diagnosis , Strongyloidiasis/drug therapy , Strongyloidiasis/microbiology , Strongyloides stercoralis/isolation & purification , Strongyloides stercoralis/microbiology , Ivermectin/therapeutic use , Strongyloidiasis/physiopathology , Strongyloidiasis/parasitology , Primary Health Care/methods , Medical History Taking/methods , Enzyme-Linked Immunosorbent Assay/methodsABSTRACT
No disponible
Subject(s)
Humans , Male , Aged, 80 and over , Strongyloides stercoralis , Strongyloides stercoralis/isolation & purification , Strongyloides stercoralis/microbiology , Lung , Lung/pathology , Lung/parasitology , Pneumonia/complications , Pneumonia/drug therapy , Piperacillin/therapeutic use , Amikacin/therapeutic use , Myiasis/complications , Myiasis/microbiology , Myiasis , Clindamycin/therapeutic use , Bronchodilator Agents/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Bronchoscopy/methodsSubject(s)
Humans , Male , Adult , Loiasis/complications , Loiasis/diagnosis , Eosinophilia/diagnosis , Strongyloides stercoralis/isolation & purification , Strongyloides stercoralis/microbiology , Eosinophilia/prevention & control , Strongyloides stercoralis/pathogenicity , Toxocara/isolation & purification , Toxocara/microbiology , Toxocara/parasitologyABSTRACT
La estrongiloidosis es una enfermedad parasitaria endémica en zonas tropicales, casi siempre asintomática, pero en pacientes inmunodeprimidos puede provocar una hiperinfección y una enfermedad diseminada severa. Presentamos el caso de una niña de 18 meses de edad, procedente de Etiopía, que acude a la consulta por presentar distensión abdominal y diarrea. Se diagnosticó inicialmente como una giardiasis, y se trató sin que se obtuviese mejoría clínica. Ante la aparición de eosinofilia y la persistencia de los síntomas, se repitieron los estudios microbiológicos y se aislaron larvas de Strongyloides stercoralis en heces. Fue tratada con albendazol, con buenos resultados. La estrongiloidosis es una enfermedad que plantea dificultades diagnósticas por su sintomatología, la escasa rentabilidad de las pruebas diagnósticas y su baja incidencia en nuestro medio. El tratamiento en adultos está bien establecido, pero en menores de 2 años hay cierta controversia en cuanto al fármaco de elección(AU)
Strongyloidiasis is a parasitic endemic disease in tropical zones, usually asymptomatic but in immunodepressed patients can induce an hyperinfection and a serious disseminated disease. We report a case of an 18 months old girl from Ethiopia, that comes to consultation with abdominal bloating and diarrhea. Initially was diagnosed and treated as a giardiasis but a clinical improvement was not obtained. Because of the rise of eosinophilia and the persistence of the symptoms, the microbiological studies were repeated and Strongyloides stercoralis larvae were detected in stools. It was treated with albendazole achieving a good result. Strongyloidiasis is a disease that implies diagnostic difficulties, for his symptomatology, for the reliability of the diagnostic tests and for the low incident in our country. The treatment in adults is well established, but in children younger than 2-year-old there is scanty information about the drug of choice(AU)
Subject(s)
Humans , Female , Infant , Strongyloides stercoralis/isolation & purification , Albendazole/therapeutic use , Diarrhea/complications , Diarrhea/diagnosis , Diarrhea/drug therapy , Intestinal Diseases, Parasitic/complications , Intestinal Diseases, Parasitic/diagnosis , Parasitic Diseases/complications , Parasitic Diseases/drug therapy , Sensitivity and Specificity , Strongyloides stercoralis/microbiology , Immunosuppressive Agents/therapeutic use , Abdominal Pain/etiology , Ivermectin/therapeutic use , Thiabendazole/therapeutic useABSTRACT
INTRODUCTION: Strongyloides stercoralis is a nematode that infects much of the population worldwide. METHODS: This study aimed to compare the ability of predatory nematophagous fungi Duddingtonia flagrans (AC001), Monacrosporium thaumasium (NF34) and Arthrobotrys robusta (I-31) on infective larvae (L3) of Strongyloides stercoralis in laboratory conditions on 2% water-agar. RESULTS: At the end of the experiment, the percentage reductions in Strongyloides stercoralis L3 were 83.7% (AC001), 75.5% (NF34) and 73.2% (I-31). CONCLUSIONS: The nematophagous fungi were able to capture and destroy the L3 in vitro and may be used as biological controls of Strongyloides stercoralis.
Subject(s)
Ascomycota/physiology , Mitosporic Fungi/physiology , Pest Control, Biological/methods , Strongyloides stercoralis/microbiology , Animals , Ascomycota/classification , Dogs , Larva/microbiology , Mitosporic Fungi/classification , Strongyloides stercoralis/growth & developmentABSTRACT
INTRODUÇÃO: Strongyloides stercoralis é um nematoide que infecta grande parte da população mundial. MÉTODOS: O objetivo deste trabalho foi comparar a capacidade predatória dos fungos nematófagos Duddingtonia flagrans (AC001), Monacrosporium thaumasium (NF34) e Arthrobotrys robusta (I-31) sobre larvas infectantes (L3) de Strongyloides stercoralis em condições laboratoriais no meio ágar-água 2 por cento. RESULTADOS: Ao final do experimento, os percentuais de redução de L3 de Strongyloides stercoralis observados foram de: 83,7 por cento (AC001); 75,5 por cento (NF34) e 73,2 por cento (I-31). CONCLUSÕES: Os fungos nematófagos foram capazes de capturar e destruir in vitro as L3, podendo ser utilizados como controladores biológicos de Strongyloides stercoralis.
INTRODUCTION: Strongyloides stercoralis is a nematode that infects much of the population worldwide. METHODS: This study aimed to compare the ability of predatory nematophagous fungi Duddingtonia flagrans (AC001), Monacrosporium thaumasium (NF34) and Arthrobotrys robusta (I-31) on infective larvae (L3) of Strongyloides stercoralis in laboratory conditions on 2 percent water-agar. RESULTS: At the end of the experiment, the percentage reductions in Strongyloides stercoralis L3 were 83.7 percent (AC001), 75.5 percent (NF34) and 73.2 percent (I-31). CONCLUSIONS: The nematophagous fungi were able to capture and destroy the L3 in vitro and may be used as biological controls of Strongyloides stercoralis.
Subject(s)
Animals , Dogs , Ascomycota/physiology , Mitosporic Fungi/physiology , Pest Control, Biological/methods , Strongyloides stercoralis/microbiology , Ascomycota/classification , Larva/microbiology , Mitosporic Fungi/classification , Strongyloides stercoralis/growth & developmentABSTRACT
Se describe un paciente de 43 años, costarricense, con tratamiento de una hernia discal por varios meses con esteroides, anti-infamatorios no esteroideos (AINES) y antihistaminicos (anti-H2), quien desarrolla un síndrome de hiperinfección por Strongyloides a nivel gástrico e intestinal, acompañándose de bacteremia por bacilos gram negativos y compromiso sistémico, resolviendo luego de terapia intensiva y multidisciplinaria.
