Subject(s)
Asphyxia Neonatorum/etiology , Thrombosis/complications , Umbilical Arteries , Adult , Asphyxia Neonatorum/diagnostic imaging , Asphyxia Neonatorum/embryology , Cardiopulmonary Resuscitation , Female , Gestational Age , Humans , Infant, Newborn , Intensive Care, Neonatal , Male , Pregnancy , Thrombosis/diagnostic imaging , Thrombosis/embryology , Ultrasonography, Prenatal , Umbilical Arteries/diagnostic imagingSubject(s)
Fetal Distress/diagnostic imaging , Pulmonary Artery , Thrombosis/embryology , Adult , Chylothorax/congenital , Chylothorax/therapy , Dilatation, Pathologic , Fatal Outcome , Female , Humans , Hydrops Fetalis/therapy , Indomethacin/adverse effects , Infant, Newborn , Thrombosis/diagnostic imaging , Tocolytic Agents/adverse effects , UltrasonographyABSTRACT
A case report of hemolytic uremic syndrome with placental involvement in 2 of 3 consecutive pregnancies highlights the impact on the fetal placental compartment and the importance of diligent antenatal care in subsequent pregnancies.
Subject(s)
Hemolytic-Uremic Syndrome/complications , Placenta/blood supply , Pregnancy Complications , Thrombosis/embryology , Thrombosis/etiology , Adult , Female , Humans , Maternal-Fetal Exchange , Pregnancy , RecurrenceABSTRACT
Fetal vessels in the placentas of 11 of 15 infants with cerebral palsy contained thrombi. An alternate basis for the injury was identified in the four placentas without thrombi. Autopsy findings in one infant who died at age 1 month confirmed the presence of cerebral thrombi and infarcts. It is concluded that thrombotic events in utero may explain the pathogenesis of many instances of cerebral palsy and that identification of a coagulopathy in parents could potentially identify those at risk and provide a basis for preventive treatment during pregnancy.
Subject(s)
Cerebral Palsy/etiology , Chorionic Villi/blood supply , Fetal Diseases/pathology , Fetus/pathology , Placenta Diseases/pathology , Thrombosis/pathology , Chorionic Villi/pathology , Female , Fetal Diseases/physiopathology , Gestational Age , Humans , Parity , Placenta Diseases/physiopathology , Pregnancy , Thrombosis/embryology , Vascular DiseasesSubject(s)
Chorionic Villi/blood supply , Chorionic Villi/pathology , Fetal Diseases/pathology , Placenta Diseases/pathology , Thrombosis/pathology , Vasculitis/pathology , Adult , Chronic Disease , Female , Fetal Diseases/physiopathology , Humans , Infant, Newborn , Male , Placenta Diseases/physiopathology , Pregnancy , Thrombosis/embryology , Vasculitis/embryologyABSTRACT
A case of hydrops fetalis associated with inferior vena cava thrombosis is described. Although in the literature this association is always listed, this is the first report of a well-documented case.
Subject(s)
Edema/embryology , Thrombosis/embryology , Vena Cava, Inferior , Edema/complications , Edema/diagnosis , Female , Humans , Pregnancy , Prenatal Diagnosis , Thrombosis/complications , Thrombosis/diagnosis , UltrasonographySubject(s)
Thrombosis/embryology , Adult , Female , Gestational Age , Humans , Pregnancy , Renal Veins/pathologyABSTRACT
A boy was found on the day of birth to have hypertension and radiological evidence of calcification of the left renal vein. Persistent hypokalaemia and hyper-reninaemia in the presence of a small left kidney and normal right kidney led to the decision to perform a left nephrectomy. The biopsied specimen showed old calcified renal vein thrombosis with accompanying medullary necrosis. Postoperatively hypertension resolved.
Subject(s)
Hypertension, Renal/congenital , Renal Veins , Thrombosis/complications , Humans , Hypertension, Renal/etiology , Infant, Newborn , Kidney/pathology , Male , Renal Veins/pathology , Thrombosis/embryology , Thrombosis/pathologyABSTRACT
Mouse foetuses were treated by Thalidomide on days 11-12 in order to verify whether the drug would induce blood abnormalities leading to circulatory troubles. About 18% of the treated foetuses showed both severe limb haemorrhages on day 14, and obvious alterations of the nucleated red blood cells of vitelline origin. These blood abnormalities, occurring suddenly during the well-known 'critical stage' of foetal development, could be responsible for circulatory blocks leading to necrosis.
