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1.
Arch Argent Pediatr ; 107(5): 456-8, 2009 Oct.
Article in Spanish | MEDLINE | ID: mdl-19809769

ABSTRACT

Poisoning due to amitraz together with its solvent xilene, is an unusual condition although may be increasing in rural areas where it is used as insecticide-ectoparasiticide.1-3 At present, there is scare references to orient physicians concerning its handling in childhood. We present the case of a 2-year-old boy who suffered an accidental intake of amitraz and was admitted into our Pediatric Intensive Care Unit requiring mechanical ventilation. We consider the usefulness of informing the medical community about this case so as to be aware of this rare kind of poisoning in our community.


Subject(s)
Insecticides/poisoning , Toluidines/poisoning , Child, Preschool , Humans , Male
2.
Vet Hum Toxicol ; 45(3): 124-7, 2003 Jun.
Article in English | MEDLINE | ID: mdl-12776786

ABSTRACT

This study compared the efficacy of yohimbine with atipamezole, a new alpha2 adrenergic antagonist, to treat canine amitraz intoxication. Thirty dogs were divided equally into 3 groups (A, AY, and AA). Group A received 2.5% amitraz iv at 1 mg/kg; Group AY received the same dose of amitraz followed 30 min later by 0.1 mg/kg (2 mg/mL) yohimbine iv; and Group AA received the same dose of amitraz followed 30 min later by 0.2 mg/kg (5 mg/ mL) atipamezole iv. Temperature, heart rate, respiratory frequency, mean arterial pressure, degree of sedation, mean time of tranquilization and diameter of pupils were monitored for 360 min. Sedation, loss of reflexes, hypothermia, bradycardia, hypotension, bradypnea and mydriasis were observed in Group A, with 3rd eyelid prolapse, increased diuresis and vomiting in some animals. Yohimbine reversed all alterations induced by amitraz, but induced significant cardiorespiratory effects such as tachycardia and tachypnea. Atipamezole was a useful antagonist for amitraz, with less cardiorespiratory effects, suggesting its potential role as an alternative treatment of amitraz intoxication in dogs.


Subject(s)
Adrenergic alpha-Antagonists/therapeutic use , Dog Diseases/drug therapy , Imidazoles/therapeutic use , Toluidines/poisoning , Yohimbine/therapeutic use , Adrenergic alpha-Antagonists/administration & dosage , Animals , Dogs , Female , Imidazoles/administration & dosage , Infusions, Intravenous/veterinary , Male , Poisoning/drug therapy , Poisoning/veterinary , Treatment Outcome , Yohimbine/administration & dosage
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