ABSTRACT
El objetivo de esta publicación es continuar con el tema desarrollado en la primera parte, donde se esbozaron aspectos generales de la organización de la oclusión, como introducción al estudio de la etiopa- togenia de las maloclusiones, con el factor dentario como aspecto central. Probablemente es el que com- parte mayor presencia en maloclusiones, donde el factor principal es de otro origen, es decir, esqueletal o neuromuscular. Se expondrá, a continuación, la condición del espacio en los arcos dentarios, sea por exceso o defecto de material dentario, sea por pérdida de perímetro del arco dentario, en cuanto al diagnóstico y a conductas preventivas. La parte III se centrará en alteraciones de erupción dentaria (AU)
The objective of this publication is to continue with the theme developed in the first part, where general aspects of the organization of the occlusion were outlined, as an introduction to the study of the etiopathogenesis of malocclusions, with the dental factor as a central aspect. It is probably the one that shares the greatest presence in malocclusions where the main factor is of another origin, that is, skeletal or neuromuscular. Next, the condition of the space in the dental arches will be exposed, whether due to excess or defect of dental material or loss of perimeter of the dental arch, in terms of diagnosis and preventive behaviors. Part III will focus on dental eruption disorders (AU)
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Dental Occlusion , Malocclusion/etiology , Patient Care Planning , Tooth, Deciduous/physiopathology , Tooth Socket/physiopathology , Dentition, Mixed , Malocclusion/classification , Maxillofacial Development/physiology , Odontometry/methodsABSTRACT
The purpose of this study is to evaluate the dimensional changes that occur in the alveolar ridge after minimally traumatic tooth extraction by means of computed tomography (CT), with special focus on the portion of bone supporting the gingival zenith. Twenty subjects with indication for singlerooted tooth extraction and preserved alveolar walls were selected for this study. After a minimally traumatic extraction, two CT scans were performed; the first within 24 hours postextraction (TC1) and the second 6 months (TC2) later. A radiographic guide with a radiopaque marker was used to obtain references that enabled accurate measurements over time, in both vertical and horizontal directions. The bone crest immediately apical to the gingival zenith was identified and termed osseous zenith. The displacement of the osseous zenith in horizontal and vertical direction was analyzed and correlated with several alveolar anatomical variables with the aim of identifying possible predictors for bone remodeling. Dimensional changes that occur in postextraction sockets within a 6month period showed significant vertical and horizontal displacement of the osseous zenith (p<0.001). Mean vertical resorption was 2.1 ± 1.7 mm, with a median of 1.9 mm and a range of 0.2 to 7.5 mm. Mean horizontal resorption was 1.8 ± 0.8 mm with a median of 1.7 mm and a range of 0.6 to 4.4 mm. However, no correlation was found between the width of the facial alveolar crest and the displacement of the osseous zenith. The results of the present study showed that if the width of the facial crest at the apicalcoronal midpoint is less than 0.7 mm, a high degree of displacement of the osseous zenith (> 3 mm) should be expected. The present study suggests that the width of the alveolar crest at its midlevel, rather than crestal width, may be correlated with the displacement of the osseous zenith.
El objetivo del presente estudio es evaluar los cambios dimen sio nales que ocurren en el reborde alveolar luego de realizar una exodoncia atraumática mediante tomografía computada, con especial atención en el tejido óseo que soporta el cénit gingival. Se seleccionaron 20 sujetos con indicación de exodoncia de piezas unirradiculares y que presentaban las paredes alveolares conservadas. Luego de llevar a cabo una exodoncia atraumática se realizaron dos tomografías computadas (TC); la primera dentro de las 24 hs postexodoncia (TC1) y la segunda a los 6 meses (TC2). Se utilizó una guía radiológica con un marcador radiopaco para obtener medidas precisas en el tiempo, tanto en el plano horizontal como vertical. Se identificó la cresta ósea inmediatamente apical al cénit gingival y se definió como cénit óseo. Se realizó un análisis del desplazamiento del cénit óseo en el plano horizontal y vertical y se correlacionó con diferentes variables anatómicas con el objetivo de determinar posibles predictores del remo delado óseo. Los cambios dimensionales que ocurren 6 meses postexodoncia mostraron un desplazamiento significativo del cénit óseo (p<0.001) . La reabsorción vertical promedio fue de 2.1 ± 1.7 mm con una media de 1.9 mm y un rango de 0.2 a 7.5 mm. El promedio de reabsorción horizontal fue de 1.8 ± 0.8 mm con una media de 1.7 mm y un rango de 0.6 a 4.4 mm. No se halló correlación entre el ancho de la cresta vestibular y el desplazamiento del cénit óseo. Los resultados del presente estudio mostraron que si el ancho de la cresta vestibular en el punto medio (en sentido apicocoronal) es menor a 0.7mm se puede esperar un desplazamiento del cénit óseo (>3mm). Este estudio sugiere que el ancho de la cresta alveolar en su punto medio podría predecir el desplazamiento del cénit óseo.
Subject(s)
Humans , Male , Female , Tooth Socket/physiopathology , Tooth Extraction/adverse effects , Dental Implantation, Endosseous/methods , Alveolar Bone Loss/etiology , Tomography, X-Ray Computed/methods , Argentina , Tooth Socket , Wound Healing/physiology , Schools, Dental , Alveolar Bone Loss , Minimally Invasive Surgical Procedures/methods , Data Interpretation, StatisticalABSTRACT
La regeneración ósea guiada es una técnica capaz depromover la neoformación ósea. A través de la aplicaciónde la misma se pueden corregir los defectosóseos como dehiscencias, fenestraciones y defectoscircunferenciales similares a los causados por unaextracción dentaria. Esta técnica permite además, elaumento horizontal y vertical del reborde alveolar.La finalidad de este trabajo es la de realizar una revisiónbibliográfica para evaluar los beneficios de laregeneración ósea guiada en defectos de tipo II.
Guided bone regeneration is a techniquecapable of promoting the new bone formation.The bone defects such as dehiscences andfenestrations circumferential defects similar to thosecaused by a tooth extraction could becorrect through the application of the same.This technique also allows increased horizontaland vertical alveolar ridge. The purpose of thiswork is the carry out of a literature review toevaluate the benefits of bone regenerationguided defects in type II.
Subject(s)
Humans , Female , Tooth Socket/physiopathology , Alveolar Ridge Augmentation/instrumentation , Alveolar Ridge Augmentation/methods , Bone Regeneration , Alveolar Bone Loss/therapy , Tooth Extraction/adverse effects , Membranes, Artificial , Biocompatible Materials/classification , Biocompatible Materials/therapeutic use , Surgical Flaps , Bone Transplantation/instrumentation , Bone Transplantation/methodsABSTRACT
A diabetes mellitus (DM) é um grupo de doenças metabólicas caracterizadas por hiperglicemia resultante do déficit na secreção e/ou ações de insulina. Dentre as muitas complicações da diabetes incluem a osteopenia diabética, que causa osteoporose e aumento do risco de fraturas ósseas. A patofisiologia da baixa resistência óssea associada a DM é considerada multifatorial, podendo ser decorrente da deficiência de insulina, resistência à insulina, insuficiência de osteoblastos, deficiência de vitamina D, formação e acúmulo dos produtos finais da glicação avançada e complicações microvasculares. Por isso, existe um interesse crescente no estudo da diabetes associada a outras alterações metabólicas e o efeito das drogas antidiabéticas, de forma a reverter os efeitos maléficos. O objetivo desse estudo foi avaliar a influência das drogas antidiabéticas na movimentação dentária ortodôntica e na densidade/microarquitetura óssea alveolar em ratos diabéticos. Assim, ratos Normoglicêmicos (NG,n=20) e Diabéticos induzidos pela estreptozotocina (DM1,n=60) foram divididos em: TinDM1(n=20) tratados com Insulina, TinmetDM1(n=20) tratados com Insulina+Metformina, e os STDM1(n=20) e STNG(n=20) que não receberam tratamento. Após 14 dias da indução, o 1o molar superior direito recebeu força ortodôntica (50g) em sentido mesial. Nos periodos experimentais de 0, 3, 7 e 14 dias, as maxilas foram coletadas e submetidas às análises microtomográficas para quantificar a movimentação dentária e a densidade óssea e histológica, para avaliar as alterações periodontais ocorridas durante a movimentação. Os dados microtomográficos foram submetidos à ANOVA a dois critérios e teste de Tukey (p<0,05). A indução com estreptozotocina induziu ao quadro de diabetes grave (glicemia de jejum de 325mg/dL) os quais foram acentuados com o tempo no grupo STDM1 (404mg/dL). A utilização de insulina e da associação insulina e metformina reduziram consideravelmente os níveis glicêmicos (127mg/dL)...
Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia resulting in deficits in the secretion and/or insulin action. Among the many complications of diabetes, it includes diabetic osteopenia that causes osteoporosis and increased risk of bone fractures. The pathophysiology associated with low bone strength in DM is considered multifactorial and may be due to insulin deficiency, insulin resistance, osteoblast deficiency, vitamin D deficiency, formation and accumulation of advanced glycation end products and microvascular complications. Therefore, there is a growing interest in the study of diabetes associated with other metabolic abnormalities and the effect of antidiabetic drugs, in order to reverse the deleterious effects. The objective of this study was to evaluate the influence of antidiabetic drugs in orthodontic tooth movement and alveolar bone density/microarchitecture in diabetic rats. Thus, normoglycemic rats (NG, n=20) and streptozotocin-induced diabetic (DM1, n=60) were divided into TinDM1 (n=20) treated by insulin, TinmetDM1 (n=20) treated by Insulin + Metformin and STDM1 (n = 20) and STNG (n = 20) that received no treatment. After 14 days of induction, the M1 received orthodontic force (50g) to move mesially. After 0, 3, 7 and 14 days jaws were collected and subjected to microtomographic images analysis to quantify, tooth movement and bone density and histological analysis to evaluate periodontal changes occurred during the movement. Microtomographic data were submitted to two-way ANOVA and Tukey test (p <0.05). The induction with streptozotocin induced severe diabetes frame (fasting blood glucose 325 mg/dL) which accentuated over the time of the disease in STDM1 group (404mg/dL). The use of insulin and insulin and metformin reduced blood glucose levels to satisfactory values (127mg/dL). The strength of 50g applied on M1 promoted linear tooth movement, being lower in STNG group...
Subject(s)
Animals , Male , Rats , Tooth Socket , Diabetes Mellitus, Experimental/drug therapy , Diabetes Mellitus, Type 1/drug therapy , Hypoglycemic Agents/pharmacology , Tooth Movement Techniques , Tooth Socket/physiopathology , Body Mass Index , Diabetes Mellitus, Experimental/physiopathology , Diabetes Mellitus, Type 1/physiopathology , Rats, Wistar , Time Factors , Tomography, X-Ray ComputedABSTRACT
La colocación de implantes dentales es una alternativa de tratamiento que ofrece La colocación de implantes dentales son una alternativa de tratamiento que ofrece buenos resultados para dientes que por distinta causa están indicados a la exodoncia. Los implantes dentales inmediatos a la extracción dental surgen a la exigencia de acortar los tiempos de tratamiento y, sobre todo, a la necesidad de preservar las estructuras alveolares que sin ellas estarían destinadas a atrofiarse. Presentamos un caso tratado con la colocación de un implante post extracción y el manejo de tejidos periimplantarios con provisionalización inmediata.
Dental Implant placement is a treatment option that provides good results for teeth thatby any chance have been planned to be extracted Immediate implants arise for the requi-rement to shorten overall treatment time but also to preserve alveolar structures whichwill atrophy without them. We present a case report about an immediate dental implantand immediate provisionalization to manage peri-implant tissues.
Subject(s)
Female , Dental Implants, Single-Tooth , Denture, Partial, Temporary , Tooth Extraction , Tooth Socket/physiopathology , Biocompatible Materials , Osteogenesis/physiology , Phosphates , Gingival Recession/prevention & control , Bone Resorption/prevention & controlABSTRACT
La colocación de implantes dentales es una alternativa de tratamiento que ofrece La colocación de implantes dentales son una alternativa de tratamiento que ofrece buenos resultados para dientes que por distinta causa están indicados a la exodoncia. Los implantes dentales inmediatos a la extracción dental surgen a la exigencia de acortar los tiempos de tratamiento y, sobre todo, a la necesidad de preservar las estructuras alveolares que sin ellas estarían destinadas a atrofiarse. Presentamos un caso tratado con la colocación de un implante post extracción y el manejo de tejidos periimplantarios con provisionalización inmediata. (AU)
Dental Implant placement is a treatment option that provides good results for teeth thatby any chance have been planned to be extracted Immediate implants arise for the requi-rement to shorten overall treatment time but also to preserve alveolar structures whichwill atrophy without them. We present a case report about an immediate dental implantand immediate provisionalization to manage peri-implant tissues.(AU)
Subject(s)
Female , Dental Implants, Single-Tooth , Tooth Extraction , Denture, Partial, Temporary , Bone Resorption/prevention & control , Tooth Socket/physiopathology , Gingival Recession/prevention & control , Biocompatible Materials , Phosphates , Osteogenesis/physiologyABSTRACT
BACKGROUND: The presence of an adequate zone of keratinized tissue has been associated with implant health. This study evaluated the increasing of the zone of keratinized tissue using dense polytetrafluoroethylene (d-PTFE) membranes over extraction sites, without primary closure. MATERIALS AND METHODS: Fifteen sites received d-PTFE membranes. The control sites received no membranes. All cases were sutured with no attempt to achieve primary closure. Before surgery, initial measurements of buccal and lingual keratinized tissue were taken from the mucogingival line (MGL) to the most coronal gingival margins. Final measurements were taken from the buccal MGL to the lingual MGL, 60 and 90 days after extractions. RESULTS: In the test group, a mean increase in the zone of keratinized tissue of 7.06 ± 2.63 mm and 6.6 ± 2.84 mm was observed in 60 and 90 days, respectively. In the control group, a mean increase of 2.46 ± 1.59 mm and 1.40 ± 1.40 mm was observed in 60 and 90 days, respectively. CONCLUSION: Nonexpanded d-PTFE membranes can predictably be used to increase the zone of keratinized tissue in preparation to implant placement.
Subject(s)
Keratins/metabolism , Polytetrafluoroethylene , Tooth Socket/physiopathology , Bone Regeneration/physiology , Gingiva/physiopathology , Humans , Membranes , Tooth Extraction/adverse effects , Tooth Extraction/methodsABSTRACT
BACKGROUND: Orthodontic procedures are often limited by the presence of bone defects caused by trauma, periodontal diseases or surgeries, thus requiring the development of materials capable to compensate such deficiencies. Since bone morphogenetic proteins (BMPs) are indicative of bone reconstitution, this study aimed to evaluate histological and immunohistochemically the temporal location of BMP-2 and BMP-4 in osteoblasts of rat alveolar wounds filled with demineralized human dentine matrix (DHDM), used as a graft material. METHODS: After extraction of the upper second molars, the left side alveoli were filled with DHDM and the right side served as the control. The animals were euthanized after 3, 5, 10 and 14 days of surgery. After fixation, demineralization and paraffin embedding, representative samples of each group were stained with H&E and immunohistochemically evaluated. RESULTS: The data showed a statistically significant (p < 0.05) increased number of osteoblasts positively immunostained for BMP-2 and BMP-4 on the experimental side (left) at 10 days. Our results also showed that even when not degraded, dentine matrix was incorporated to new bone formation after 14 days of surgery. CONCLUSIONS: The results suggest that DHDM acts as a scaffold for osteoblast differentiation, actively yielding new bone formation, and it may represent an effective bone implant material.
Subject(s)
Bone Morphogenetic Protein 2/metabolism , Bone Morphogenetic Protein 4/metabolism , Dentin , Osteoblasts/metabolism , Osteogenesis/physiology , Tooth Socket/physiopathology , Wound Healing/physiology , Animals , Bone Morphogenetic Protein 2/analysis , Bone Morphogenetic Protein 4/analysis , Dentin/metabolism , Humans , RatsABSTRACT
UNLABELLED: Hypertension is one of the most important public health problems worldwide. If undiagnosed or untreated, this pathology represents a systemic risk factor and offers unfavorable conditions for dental treatments, especially those requiring bone healing. OBJECTIVES: The purpose of this study was to demonstrate, by analysis of bone mineral density (BMD), that the alveolar bone healing process is altered in spontaneously hypertensive rats (SHRs). MATERIAL AND METHODS: Wistar rats and SHRs were submitted to extraction of the upper right incisor and were euthanized 7, 14, 21, 28 and 42 days after surgery. Right maxillae were collected, radiographed and analyzed using Digora software. BMD was expressed as minimum (min), middle (med) and maximum (max) in the medium (MT) and apical (AT) thirds of the dental alveolus. RESULTS: The results were compared across days and groups. Wistar showed difference in med and max BMD in the MT between 7 and 28 and also between 14 and 28 days. The AT exhibited significant difference in med and min BMD between 7 and 28 days, as well as difference in min BMD between 28 and 42 days. SHRs showed lower med BMD in the MT at 28 days when compared to 21 and 42 days. Differences were observed across groups in med and min BMD at day 28 in the MT and AT; and in max BMD at 14, 21 and 42 days in the MT. CONCLUSIONS: These results suggest that the alveolar bone healing process is delayed in SHRs comparing with Wistar rats.
Subject(s)
Bone Regeneration/physiology , Hypertension/physiopathology , Tooth Socket/physiopathology , Wound Healing/physiology , Animals , Blood Pressure/physiology , Densitometry , Disease Models, Animal , Hypertension/complications , Male , Radiography , Rats , Rats, Inbred SHR , Rats, Wistar , Species Specificity , Time Factors , Tooth Socket/diagnostic imagingABSTRACT
Hypertension is one of the most important public health problems worldwide. If undiagnosed or untreated, this pathology represents a systemic risk factor and offers unfavorable conditions for dental treatments, especially those requiring bone healing. Objectives: The purpose of this study was to demonstrate, by analysis of bone mineral density (BMD), that the alveolar bone healing process is altered in spontaneously hypertensive rats (SHRs). Material and Methods: Wistar rats and SHRs were submitted to extraction of the upper right incisor and were euthanized 7, 14, 21, 28 and 42 days after surgery. Right maxillae were collected, radiographed and analyzed using Digora software. BMD was expressed as minimum (min), middle (med) and maximum (max) in the medium (MT) and apical (AT) thirds of the dental alveolus. Results: The results were compared across days and groups. Wistar showed difference in med and max BMD in the MT between 7 and 28 and also between 14 and 28 days. The AT exhibited significant difference in med and min BMD between 7 and 28 days, as well as difference in min BMD between 28 and 42 days. SHRs showed lower med BMD in the MT at 28 days when compared to 21 and 42 days. Differences were observed across groups in med and min BMD at day 28 in the MT and AT; and in max BMD at 14, 21 and 42 days in the MT. Conclusions: These results suggest that the alveolar bone healing process is delayed in SHRs comparing with Wistar rats.
Subject(s)
Animals , Male , Rats , Bone Regeneration/physiology , Hypertension/physiopathology , Tooth Socket/physiopathology , Wound Healing/physiology , Blood Pressure/physiology , Densitometry , Disease Models, Animal , Hypertension/complications , Rats, Inbred SHR , Rats, Wistar , Species Specificity , Time Factors , Tooth SocketABSTRACT
PURPOSE: This study radiographically evaluated the performance of autologous platelet-rich plasma (PRP) applied in tooth sockets. PATIENTS AND METHODS: Thirty extractions of bilateral impacted mandibular third molars were performed in 15 volunteers (7 men, 8 women; 18 to 22 years old). After extraction of right and left mandibular third molars, the socket at 1 side received the autologous PRP (PRP group) and the other was filled with blood clot (control group). Millimeter periapical radiographs were obtained 7 days, 1 month, and 2, 3, and 6 months postoperatively. Radiographic bone density was quantified 3 times by the same examiner at different moments using HLImage 97 software, and data were statistically analyzed by Statgraf 7.0 software (analysis of variance and Tukey test). RESULTS: In general, there was significantly faster bone formation in sockets treated with PRP (P < .01). Significant bone formation was observed in the first month (P < .01), second month (P < .05), and third month (P < .01) for the PRP group. No statistical differences were observed on the seventh day and sixth month of investigation, yet there were higher means of radiographic bone density in sockets treated with PRP. In the control group, men exhibited significant bone repair compared with women (P < .05). CONCLUSION: Autologous PRP was found to accelerate alveolar bone regeneration, and men presented better repair after tooth extraction.
Subject(s)
Alveolar Process/diagnostic imaging , Mandible/surgery , Molar, Third/surgery , Platelet-Rich Plasma/physiology , Tooth, Impacted/surgery , Adolescent , Alveolar Process/physiopathology , Blood Coagulation/physiology , Bone Density/physiology , Bone Regeneration/physiology , Female , Follow-Up Studies , Humans , Male , Mandible/diagnostic imaging , Osteogenesis/physiology , Radiography, Bitewing , Sex Factors , Surgical Flaps , Suture Techniques , Tooth Socket/physiopathology , Tooth Socket/surgery , Transplantation, Autologous , Wound Healing/physiology , Young AdultABSTRACT
A proposta deste estudo consistiu em avaliar, cefalometricamente, as alterações dentárias e esqueléticas promovidas pelos aparelhos MARA e Bionator, seguidos do aparelho ortodôntico fixo, no tratamento da má oclusão de Classe II, 1ª divisão. A amostra foi composta por 40 pacientes, divididos em dois grupos. O Grupo MARA foi composto por 18 jovens, 12 do gênero masculino e 6 do gênero feminino, sendo que, 22,22% apresentavam ½ Classe II, 38,89% ¾ de Classe II e 38,89% Classe II completa nos molares. A idade inicial variou entre 10,29 anos e 14,99 anos (média de 11,96 anos). Estes pacientes foram selecionados prospectivamente entre os jovens que procuraram tratamento ortodôntico na clínica de Ortodontia da Faculdade de Odontologia de Bauru Universidade de São Paulo, durante o ano de 2006 e tratados por meio do aparelho MARA seguido do aparelho ortodôntico fixo, por um período médio de 3,47 anos. O Grupo Bionator, composto por 22 jovens, sendo 13 do gênero masculino e 9 do gênero feminino, com idade inicial média de 11,38 anos, apresentavam 27,27% dos indivíduos com ½ Classe II, 27,27% ¾ de Classe II e 45,45% Classe II completa nos molares. Foram selecionados retrospectivamente a partir do acervo da Disciplina de Ortodontia da Faculdade de Odontologia de Bauru Universidade de São Paulo e tratados por meio do aparelho Bionator seguido do aparelho ortodôntico fixo, por um período médio de 3,95 anos. Para cada paciente foram utilizadas duas telerradiografias em norma lateral, uma na fase inicial e outra ao término do tratamento ortodôntico fixo. Utilizou-se o teste t de Student, para amostras independentes, a fim de se comparar as idades iniciais e finais, o tempo de tratamento, as variáveis cefalométricas iniciais e finais e as alterações médias reais na comparação intergrupos. O gênero dos jovens e a severidade da má oclusão entre os grupos foram avaliados pelo teste do Qui-quadrado. Para avaliar as alterações iniciais e finais dentro de...
This study aimed to evaluate, cephalometrically, dental and skeletal changes promoted by the MARA and Bionator, followed by fixed appliances on the treatment of Class II, Division 1 malocclusion. The sample comprised 40 young subjects, divided into two groups. MARA Group, was comprised 18 patients, 12 males and 6 females, among which 22.22% exhibited ½-cusp Class II, 38.89% ¾-cusp Class II, and 38.89% full-cusp Class II malocclusions (molar relationship). The initial age ranged from 10.29 years to 14.99 years (mean of 11.96 years). These patients were prospectively selected among young subjects who seek orthodontic treatment at the Orthodontic Department at Bauru Dental School, University of São Paulo, Brazil, during 2006 and treated with the MARA appliance followed by fixed appliances for a mean period of 3.47 years. Bionator Group, consisted of 22 patients, 13 males and 9 females, with initial mean age of 11.38 years; 27.27% exhibited ½-cusp Class II, 27.27% ¾-cusp Class II and 45.45% full-cusp Class II malocclusions (molar relationship). These patients were retrospectively selected from the files of the Orthodontic Department at Bauru Dental School, University of São Paulo, Brazil and treated with the Bionator followed by fixed appliances for a mean period of 3.95 years. The initial and final lateral cephalograms of individuals in the two groups were evaluated. The Student t test for independent samples was applied to compare the initial and final ages, the period of treatment, the initial and final cephalometric variables and the actual mean changes between the two groups. The distribution of genders and the severity of malocclusion between the groups were evaluated by the chi-square test. The changes between the initial and final stages of each group were evaluated by the t test for dependent samples. The results showed that, for both appliances, there was no significant change in maxillary and mandibular development, in the maxillomandibular...
Subject(s)
Humans , Male , Female , Child , Adolescent , Activator Appliances , Cephalometry , Malocclusion, Angle Class II/therapy , Age Factors , Tooth Socket/physiopathology , Orthodontics, Corrective/methods , Statistics, NonparametricABSTRACT
PURPOSE: The purpose of this study was to evaluate the effects of nicotine and ovariectomy on alveolar bone regeneration after exodontias in rats. MATERIALS AND METHODS: For 30 days, sham ovariectomized (OVX)/NaCl, sham OVX/nicotine, OVX/NaCl, and OVX/nicotine animals were given 2 daily injections of saline or hemisulfate of nicotine. After this period, exodontic procedures were carried out and treatment continued up to the time of euthanasia on days 7 and 14 when the alveoli were removed for further analyses. RESULTS: The data confirmed that nicotine significantly delays the alveolar regeneration process after dental extraction in rats and showed that the association of nicotine with ovariectomy exacerbates these results. CONCLUSION: These results indicate that nicotine potentiated the effect of estrogen deficiency on bone regeneration induced by ovariectomy.
Subject(s)
Alveolar Process/physiopathology , Bone Regeneration/physiology , Nicotine/pharmacology , Ovariectomy , Tooth Extraction , Alveolar Process/drug effects , Alveolar Process/pathology , Animals , Bone Regeneration/drug effects , Connective Tissue/pathology , Epithelium/pathology , Estrogens/deficiency , Estrogens/physiology , Female , Fibroblasts/pathology , Gingiva/pathology , Incisor/surgery , Injections, Subcutaneous , Lymphocytes/pathology , Macrophages/pathology , Maxilla/surgery , Neovascularization, Physiologic/physiology , Nicotine/administration & dosage , Osteoblasts/pathology , Osteogenesis/drug effects , Osteogenesis/physiology , Rats , Rats, Wistar , Time Factors , Tooth Socket/drug effects , Tooth Socket/pathology , Tooth Socket/physiopathologyABSTRACT
Epidemiological studies have suggested that cola beverage consumption may affect bone metabolism and increase bone fracture risk. Experimental evidence linking cola beverage consumption to deleterious effects on bone is lacking. Herein, we investigated whether cola beverage consumption from weaning to early puberty delays the rate of reparative bone formation inside the socket of an extracted tooth in rats. Twenty male Wistar rats received cola beverage (cola group) or tap water (control group) ad libitum from the age of 23 days until tooth extraction at 42 days and euthanasia 2 and 3 weeks later. The neoformed bone volume inside the alveolar socket was estimated in semi-serial longitudinal sections using a quantitative differential point-counting method. Histological examination suggested a decrease in the osteogenic process within the tooth sockets of rats from both cola groups, which had thinner and sparser new bone trabeculae. Histometric data confirmed that alveolar bone healing was significantly delayed in cola-fed rats at three weeks after tooth extraction (ANOVA, p = 0.0006, followed by Tukey's test, p < 0.01). Although the results of studies in rats cannot be extrapolated directly to human clinical dentistry, the present study provides evidence that cola beverage consumption negatively affect maxillary bone formation.
Subject(s)
Bone Regeneration/drug effects , Carbonated Beverages/adverse effects , Tooth Socket/drug effects , Analysis of Variance , Animals , Bone Density , Bone Regeneration/physiology , Disease Models, Animal , Male , Osteogenesis/drug effects , Osteogenesis/physiology , Rats , Rats, Wistar , Time Factors , Tooth Extraction , Tooth Socket/physiopathologyABSTRACT
Epidemiological studies have suggested that cola beverage consumption may affect bone metabolism and increase bone fracture risk. Experimental evidence linking cola beverage consumption to deleterious effects on bone is lacking. Herein, we investigated whether cola beverage consumption from weaning to early puberty delays the rate of reparative bone formation inside the socket of an extracted tooth in rats. Twenty male Wistar rats received cola beverage (cola group) or tap water (control group) ad libitum from the age of 23 days until tooth extraction at 42 days and euthanasia 2 and 3 weeks later. The neoformed bone volume inside the alveolar socket was estimated in semi-serial longitudinal sections using a quantitative differential point-counting method. Histological examination suggested a decrease in the osteogenic process within the tooth sockets of rats from both cola groups, which had thinner and sparser new bone trabeculae. Histometric data confirmed that alveolar bone healing was significantly delayed in cola-fed rats at three weeks after tooth extraction (ANOVA, p = 0.0006, followed by Tukey's test, p < 0.01). Although the results of studies in rats cannot be extrapolated directly to human clinical dentistry, the present study provides evidence that cola beverage consumption negatively affect maxillary bone formation.
Subject(s)
Animals , Male , Rats , Bone Regeneration/drug effects , Carbonated Beverages/adverse effects , Tooth Socket/drug effects , Analysis of Variance , Bone Density , Bone Regeneration/physiology , Disease Models, Animal , Osteogenesis/drug effects , Osteogenesis/physiology , Rats, Wistar , Time Factors , Tooth Extraction , Tooth Socket/physiopathologyABSTRACT
The definition of an optimal elastic modulus for a post is controversial. This work hypothesized that the influence of the posts' elastic modulus on dentin stress concentration is dependent on the load direction. The objective was to evaluate, using finite element analysis, the maximum principal stress (sigma(max)) on the root, using posts with different elastic modulus submitted to different loading directions. Nine 3D models were built, representing the dentin root, gutta-percha, a conical post and the cortical bone. The softwares used were: MSC.PATRAN2005r2 (preprocessing) and MSC.Marc2005r2 (processing). Load of 100 N was applied, varying the directions (0 degrees, 45 degrees and 90 degrees) in relation to the post's long axis. The magnitude and direction of the sigma(max) were recorded. At the 45 degrees and 90 degrees loading, the highest values of sigma(max) were recorded for the lowest modulus posts, on the cervical region, with a direction that suggests debonding of the post. For the 0 degrees loading, the highest values of sigma(max) were recorded for higher modulus posts, on the apical region, and the circumferential direction suggests vertical root fracture. The hypothesis was accepted: the effect of the elastic modulus on the magnitude and direction of the sigma(max) generated on the root was dependent on the loading direction.
Subject(s)
Dental Pulp Cavity/physiopathology , Post and Core Technique/instrumentation , Tooth Fractures/etiology , Tooth Root/injuries , Alveolar Process/physiopathology , Computer Simulation , Dental Debonding , Dentin/physiopathology , Elastic Modulus , Finite Element Analysis , Gutta-Percha/chemistry , Humans , Imaging, Three-Dimensional/methods , Incisor/physiopathology , Materials Testing , Models, Biological , Root Canal Filling Materials/chemistry , Stress, Mechanical , Tooth Apex/physiopathology , Tooth Cervix/physiopathology , Tooth Fractures/physiopathology , Tooth Root/physiopathology , Tooth Socket/physiopathologyABSTRACT
CONTEXT: The prediction of implant treatment is directly influenced by the quality of the remaining bone after tooth extraction. AIMS: The purpose of this experimental study was to, histologically and histometrically, evaluate the bone repair process in the central areas of extraction sockets filled with platelet-rich plasma. MATERIALS AND METHODS: Four young adult male Cebus apella monkeys were used. The extraction of both right and left inferior second premolars was accomplished. After extraction, in one of the extraction sockets, coagulum was maintained while in the other it was removed; the alveolus was dried with gauze compress and filled up with platelet concentrate. For PRP production, Sonnleitner's protocol was followed. The specimens for histological and histometric assessment were obtained in 30, 90, 120 and 180 days intervals. RESULTS: In 30 days new bone formation was intense in both experimental and control sockets and no significant differences were observed between the two groups. After 90 days of the extraction, while the control group showed signs of decrease in osteogenesis, in the experimental unit, the process of bone formation and fibroblast-like cell proliferation remained intense. After 120 days, the PRP treated socket was occupied by large trabeculae of bone. After 180 days, the control unit was occupied mostly with bone marrow. The experimental unit remained occupied with large amounts of bone tissue. CONCLUSIONS: It was possible to conclude that bone repair was enhanced by the use of platelet- rich plasma in alveolar sockets.
Subject(s)
Alveolar Process/pathology , Bone Density/physiology , Platelet-Rich Plasma , Tooth Socket/pathology , Adipocytes/pathology , Alveolar Process/physiopathology , Animals , Bicuspid/surgery , Biopsy , Bone Marrow/pathology , Cebus , Cell Proliferation , Collagen , Fibroblasts/pathology , Fibroblasts/physiology , Male , Osteoblasts/pathology , Osteoblasts/physiology , Osteogenesis/physiology , Platelet-Rich Plasma/physiology , Random Allocation , Time Factors , Tooth Extraction , Tooth Socket/physiopathology , Wound Healing/physiologyABSTRACT
PURPOSE: This study was conducted to investigate the morphological effects of the absence of estrogen on alveolar wound healing of young female rats after tooth extraction. MATERIALS AND METHODS: A total of 60 4- to 6-week-old female rats underwent bilateral ovariectomy (OVX) or sham operations. Three weeks later, the first mandibular molars were extracted. Subsequently, the animals were killed by cervical dislocation 3, 5, 7, 14, 21, or 28 days after tooth extraction. The mandibles were removed, and serial transversal sections of mesial alveolus of the first mandibular molars were obtained for histometric analysis. RESULTS: OVX sockets showed significant increases in fibroblasts and collagen content 3 and 5 days after the extractions, followed by significant decreases in these parameters in the subsequent periods. In accordance with the decreased collagen content in the latest period of healing, new bone formation was significantly reduced in the OVX animals. CONCLUSION: These findings suggest that the initial molecular changes observed in the absence of estrogen lead to delayed alveolar wound healing.
Subject(s)
Alveolar Process/physiopathology , Molar/surgery , Ovariectomy , Tooth Extraction , Tooth Socket/physiopathology , Absorptiometry, Photon , Alveolar Process/pathology , Animals , Bone Density/physiology , Collagen/analysis , Estrogens/physiology , Female , Fibroblasts/pathology , Mandible/pathology , Mandible/physiopathology , Mandible/surgery , Osteogenesis/physiology , Ovary/physiology , Rats , Rats, Wistar , Tibia/pathology , Time Factors , Tooth Socket/pathology , Wound Healing/physiologyABSTRACT
Se describe el reporte de cuatro casos inusuales de alveolitis seca en los cuales el tratamiento fue inadecuado debido a la introducción accidental de cemento quirúrgico hasta el ápice del alveolo dentario. Esto ocasionó un cuadro severo de irritación ósea asociado con un dolor intenso en la zona alveolar. Después del endurecimiento del material dentro del alveolo, fue necesario realizar el fresado del cemento quirúrgico ocasionando un severo cuadro de irritación alveolar. A partir de estos hallazgos clínicos se sugiere evitar la colocación directa de cualquier cemento quirúrgico diluido, sino más bien, acompañarlo de una gasa para facilitar el retiro atraumático.
Subject(s)
Male , Female , Adult , Humans , Tooth Socket/physiopathology , Tooth Socket/injuries , Dry Socket/complications , Dry Socket/therapy , MalpracticeABSTRACT
PURPOSE: Loss of ridge width and height typically occur after tooth extraction. This study aimed to investigate whether smoking would effect alveolar ridge remodeling after tooth extraction. MATERIALS AND METHODS: Twenty-one individuals (11 nonsmokers, 10 smokers) requiring a nonmolar extraction in the upper jaw were selected. Radiographs were taken 7 and 180 days after surgery, and the following parameters obtained: alveolar process height (AH), alveolar process width (AW), radiographic bone density in the postextraction socket (BDS), and in the pre-existing bone apically (BDPB). RESULTS: Six months after surgery, intragroup analysis showed that both groups presented a significant reduction in AH, while only smokers had a significant reduction in AW, BDS, and BDPB (P < .05). Furthermore, intergroup analysis showed that smokers presented lower BDS (91.45 pixels +/- 26.62 and 59.53 pixels +/- 19.99, for nonsmokers and smokers, respectively; P = .006) and continued to present lower BDPB (129.34 pixels +/- 42.10 and 89.29 pixels +/- 29.96, for nonsmokers and smokers, respectively; P = .023). Additionally, smokers presented a tendency for lower AH and AW than nonsmokers, but this was not statistically significant. CONCLUSION: Within the limits of the present study, smoking may lead to a more significant dimensional reduction of the residual alveolar ridge and postpone postextraction socket healing.