ABSTRACT
Anti Toxoplasma antibodies were sought in 34 patients with uveitis and 20 healthy individuals by IHAT and IFAT. The total sero-positivity rate was 26.5%. The prevalence was significantly higher among patients with posterior (42.9%) than with anterior uveitis (7.1%) and control (10%) indicating significant role of Toxoplasma as an aetiologic agent of posterior uveitis. 14.4% of patients with seropositive uveitis were considered to be due to primarily acquired Toxoplasma infection as evidenced by their significant higher IFAT mean titre (576.7 +/- 322.1) than IHAT (48 +/- 18.5). The reported toxoplasmic anterior uveitis case is most probably secondary to posterior involvement.
Subject(s)
Toxoplasmosis, Ocular/congenital , Uveitis/congenital , Adult , Humans , Serologic Tests , Uveitis/parasitology , Uveitis, Anterior/congenital , Uveitis, Anterior/parasitology , Uveitis, Posterior/congenital , Uveitis, Posterior/parasitologyABSTRACT
The aetiopathogenesis of Fuchs's disease is still unknown. Recent findings indicate that the role of the sympathetic nervous system can be excluded and that the theory of heredodegeneration is a more probable explanation. A congenital predisposition to the disease which may possibly be related to some malformation of the iris vessels should be considered. This may explain why the disease is not always unilateral. The recent immunological anomalies found in the aqueous humour should be confirmed. Comparative studies of clinical, vascular, and immunological data could be of great interest in the future.