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1.
Rev. SPAGESP ; 22(1): 160-174, ene.-jun. 2021.
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155521

ABSTRACT

Há crescente interesse sobre o comportamento abusivo sofrido por trabalhadores nas cozinhas de restaurantes comerciais, uma vez que agressões físicas e verbais parecem ser comuns neste contexto laboral. Este estudo objetivou identificar a prevalência do assédio moral e descrever as características das situações em que ele ocorre entre trabalhadores da gastronomia. Participaram do estudo 160 indivíduos com graduação em gastronomia, sendo que 95 eram do sexo feminino (59,4%), com idade média de 30,81 anos (DP = 8,34). Os mesmos responderam ao Questionário Biossociodemográfico e Laboral e ao Questionário de Atos Negativos, cujos dados foram analisados descritivamente. Os resultados indicaram elevados índices de prevalência de assédio moral (63,1%) e de violência psicológica (33,8%), que alertam sobre a importância de divulgar informações sobre o assédio moral e seus prejuízos, visando a uma maneira mais saudável de gerenciar e trabalhar na cozinha.


Great interest in abusive behavior suffered by workers in commercial restaurant kitchens was observed. In this work context, verbal and physical aggression seems to be common. This study aimed to identify the prevalence of moral harassment and describe the characteristics of the situations in which it occurs among gastronomy workers. Participants were 160 individuals undergraduate in gastronomy and 95 were female (59.4%), that have an average age of 30.81 years (SD = 8.34). The participants answered the Biosociodemographic and Labor Questionnaire and the Negative Acts Questionnaire, whose data were analyzed descriptively. The results indicated high prevalence rates of moral harassment (63.1%) and psychological violence (33.8%), which warn the importance of disclosing information about bullying and its harms, aiming at a healthier way to manage and work in the kitchen.


Una creciente preocupación por el comportamiento abusivo que sufren los trabajadores en las cocinas de restaurantes comerciales ha sido observada. Esta agresión puede ser verbal o física y parece ser común en este contexto laboral. Este estudio tuvo como objetivo identificar la prevalencia del bullying y describir las características de las situaciones en las que ocurre entre los trabajadores de la gastronomía. Los participantes fueron 160 individuos con un título en gastronomía, de los cuales 95 eran mujeres (59.4%), con una edad promedio de 30.81 años (DE = 8.34). Los participantes respondieron el Cuestionario Biosociodemográfico y Laboral y el Cuestionario de Actos Negativos, cuyos datos fueron analizados descriptivamente. Los resultados indicaron altas tasas de prevalencia de acoso moral (63.1%) y violencia psicológica (33.8%), que advierten sobre la importancia de divulgar información sobre el acoso y sus daños, con el objetivo de una forma más saludable de manejar y trabajar en la cocina.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Restaurants , Work , Surveys and Questionnaires , Cooking , Aggression , Bullying , Workplace Violence , Occupational Groups
2.
Rev. SPAGESP ; 22(1): 145-159, ene.-jun. 2021. tab
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155520

ABSTRACT

Este estudo teve como objetivo identificar e analisar se os sintomas de depressão, ansiedade e estresse estão relacionados com uso de álcool, tabaco e maconha em universitários da área da saúde. Trata-se de uma pesquisa com 111 universitários matriculados em cursos da área da saúde de uma universidade da região metropolitana do Rio Grande do Sul. Os instrumentos foram Questionário de dados sociodemográficos, Depression, Anxiety and Stress Scale (DASS-21), Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Foi realizada análise descritiva dos dados e correlação de Spearman para amostras não paramétricas. As drogas mais utilizadas foram álcool, tabaco e maconha, sendo o álcool o que mais pontuou. Houve correlações significativas entre o uso de drogas com sintomas de estresse e ansiedade. Destaca-se a necessidade de atentar para o uso de substâncias realizado por universitários da área da saúde, uma vez que esta pode acarretar danos à vida acadêmica, pessoal e profissional.


This study aimed to identify the relationship between anxiety, depression, and stress symptoms and alcohol, marijuana, and tobacco use among healthcare university students. There were 111 students from healthcare courses of a private university from the state of Rio Grande do Sul's metropolitan region, Brazil, in the present sample. The instruments were sociodemographic questionnaire; Depression, Anxiety and Stress Scale (DASS-21); Alcohol, Smoking and Substance Involvement Screening Test (ASSIST). Descriptive statistics and Spearman’s correlation analyses were done. The most frequently used drug was alcohol, followed by marijuana and tobacco. There were significant correlationsbetween substance use and stress and anxiety symptoms. It is evidenced that there is a need to pay attention to drug use among healthcare students, since such use can cause damage to academic, personal and professional life.


Este estudio tuvo como objetivo identificar y analizar si los síntomas de estrés, ansiedad, depresión, están relacionados con el uso de alcohol, tabaco y marihuana en estudiantes universitariosen el área de la salud. Esta es una encuesta de 111 estudiantes universitarios inscritos en cursos del area de la salud de una Universidad en la región metropolitana de Rio Grande do Sul. Instrumentos: Cuestionario de datos sociodemográficos, Escala de depresión, ansiedad y estrés (DASS-21), Prueba de detección de alcohol, tabaquismo y participación de sustancias (ASSIST). Se realizó análisis descriptivo de los datos y correlación de Spearman para muestras no paramétricas. Resultados: las drogas más utilizadas fueron alcohol, tabaco y marihuana, siendo el alcohol el que obtuvo la mayor puntuación. Hubo correlaciones significativas entre el uso de drogas con síntomas de estrés y ansiedad. Se destaca la necesidad de prestar atención al uso de substancias por parte de los estudiantes universitarios en el campo de la salud, ya que esto pueden causar daños a la vida académica, personal y profesional.


Subject(s)
Humans , Male , Female , Adult , Anxiety , Signs and Symptoms , Students, Health Occupations , Tobacco Use Disorder , Universities , Cannabis , Surveys and Questionnaires , Delivery of Health Care , Depression , Tobacco Use
3.
Rev. SPAGESP ; 22(1): 114-127, ene.-jun. 2021. tab
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155518

ABSTRACT

Esse estudo parte do pressuposto de que o mindfulness poderia estar relacionado com a intimidade conjugal. Investigou-se o papel discriminante da intimidade em dois grupos de indivíduos com maiores e menores níveis de mindfulness. Partiparam 281 sujeitos, maiores de 18 anos, em relacionamento estável e em coabitação. Os mesmos responderam à Escala Filadélfia de Mindfulness e à Escala de Avaliação Pessoal de Intimidade em Relacionamentos (PAIR). Os resultados indicaram que os fatores da intimidade avaliados (comunicação, validação pessoal e abertura ao exterior) discriminaram o grupo com maiores níveis de mindfulness. O estudo sugere que indivíduos com maiores níveis de mindfulness possuem maior facilidade de desenvolver intimidade em seus relacionamentos, contribuindo para o entendimento do papel considerável dessa habilidade na conjugalidade.


This study assumes that mindfulness could be related to conjugal intimacy. The discriminating role of intimacy was investigated in two groups of individuals with higher and lower levels of mindfulness. 281 subjects, over 18 years old, participated in a stable relationship and cohabitation. They responded to the Philadelphia Mindfulness Scale and the Personal Relationship Intimacy Scale in Relationships (PAIR). The results indicated that the factors of intimacy evaluated (communication, personal validation and openness to the outside) discriminated against the group with the highest levels of mindfulness. The study suggests that individuals with higher levels of mindfulness have an easier time developing intimacy in their relationships, contributing to the understanding of the considerable role of this ability in conjugality.


Este estudio asume que la atención plena podría estar relacionada con la intimidad conyugal. El papel discriminador de la intimidad se investigó en dos grupos de individuos con niveles más altos y más bajos de atención plena. 281 sujetos, mayores de 18 años, participaron en una relación estable y en convivencia. Respondieron a la Escala de atención plena de Filadelfia y la Escala de intimidad en las relaciones personales (PAIR). Los resultados indicaron que los factores de intimidad evaluados (comunicación, validación personal y apertura al exterior) discriminaban al grupo con mayores niveles de mindfulness. El estudio sugiere que las personas con niveles más altos de atención plena tienen más facilidad para desarrollar la intimidad en sus relaciones, lo que contribuye a comprender el papel considerable de esta capacidad en la conyugalidad.


Subject(s)
Humans , Male , Adult , Role , Self Disclosure , Communication , Couples Therapy , Family Relations , Mindfulness
4.
Rev. SPAGESP ; 22(1): 54-66, ene.-jun. 2021.
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155514

ABSTRACT

A presente pesquisa teve por objetivo compreender o envolvimento paterno no contexto do divórcio/separação conjugal na perspectiva do pai separado. Realizou-se um Grupo Focal com seis pais (homens) separados e os dados foram analisados através da análise categorial temática, utilizando-se do software Atlas.ti 5.0 para organização dos dados. A perspectiva sistêmica contribuiu com a compreensão do fenômeno como um processo de transformações contínuas e recursivas, contingentes com a história de interações dos participantes. Emergiram da análise dos dados três categorias: Percepções do pai sobre o seu envolvimento com a criança; Características do envolvimento paterno do pai separado e Construção da paternidade no pós-divórcio. Os resultados demonstraram relações de interdependência entre fatores individuais, relacionais e contextuais.


The present research aimed to understand paternal involvement in the context of divorce/separation from the perspective of the separated father. A Focal Group with six separated fathers (men) was carried out and the data were analyzed through the thematic categorical analysis using Atlas.ti 5.0 software for data organization. The systemic perspective contributed to the understanding of the phenomenon as a process of continuous and recursive transformations, contingent on the history of interactions of the participants. Three categories emerged from the data analysis: Perceptions of the father about his involvement with the child; Characteristics of parental involvement of the separated father and Post-Divorce Construction of Paternity. The results showed relationships of interdependence between individual, relational and contextual factors.


La presente investigación tuvo por objetivo compreender la participación paterno en el contexto del divorcio/separación conyugal en la perspectiva del padre separado. Se realizo un Grupo Focal con seis padres (hombres) separados y los datos fueron analizados a través del análisis categorial temático, utilizando el software Atlas.ti 5.0 para la organización de los datos. La perspectiva sistémica contribuyó com la comprensión del fenómeno como um proceso de transformaciones continuas y recursivas, contingentes con la historia de interacciones de los participantes. Se emergieron del análisis de los datos três categorías: Percepciones del padre sobre su implicación com el niño; Características de la participación paterno del padre separado y Construcción de la paternidade en el pos-divorcio. Los resultados demostraron relaciones de interdependencia entre factores individuales, relacionales y contextuales.


Subject(s)
Humans , Male , Adult , Middle Aged , Paternity , Divorce , Family Characteristics , Father-Child Relations , Data Analysis
5.
Rev. SPAGESP ; 22(1): 39-53, ene.-jun. 2021. tab
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155513

ABSTRACT

A ansiedade materna é um tema relevante de pesquisa no âmbito da relação mãe-bebê, pois esse sentimento pode trazer repercussões para mãe e o desenvolvimento do bebê. Este estudo de casos múltiplos, de caráter qualitativo, teve como objetivo investigar a ansiedade materna em mães de bebês de seis a 10 meses, buscando identificar sua repercussão na díade mãe-bebê. Os achados demonstraram a presença de complicações na gravidez e no pós-parto e de eventos estressantes durante esses períodos. Em todos os casos analisados, observou-se ansiedade materna na gravidez e nos primeiros cuidados com o bebê. Sentimentos como medo, angústia, dúvidas e preocupações, relatados pelas mães, desencadearam comportamentos ansiosos, refletindo na relação mãe-bebê. A partir dos relatos deste estudo, observa-se a importância do apoio para o empoderamento das mães, para que elas assumam o papel materno com mais confiança. Salienta-se a necessidade de intervenções desde a gestação para o manejo da ansiedade materna, bem como práticas de educação em saúde visando à promoção da saúde mental materno-infantil


Maternal anxiety is an important topic of research regarding the mother-child relationship because this feeling can impact the mother and the baby's development. This qualitative study, of a multiple-case design, aimed to investigate maternal anxiety in mothers of babies aged between six and 10 months, trying to identify its impact on the mother-child dyad. The findings showed the occurrence of complications in pregnancy and the postpartum period and stressful events during these periods. In all analyzed cases, the presence of maternal anxiety during pregnancy and the newborn early care was verified. Feelings such as fear, anguish, doubts, and concerns, reported by mothers, triggered anxious behaviors, reflecting on the mother-baby relationship. From the reports of this study, the importance of support for the empowerment of mothers was observed, so that they can assume the maternal role with more confidence. It points out the need for intervention programs since pregnancy for the management of maternal anxiety, as well as health education practices aiming to promote maternal and child mental health.


La ansiedad materna es un tema relevante de investigación en el ámbito de la relación madre-hijo, ya que este sentimiento puede tener repercusiones en la madre y en el desarrollo del bebé. Este estudio cualitativo, de casos múltiples, investigó la ansiedad materna en madres de niños de seis a 10meses, buscando identificar su impacto en la díada madre-hijo. Los resultados revelaron la presencia de complicaciones en el embarazo y en el posparto, y de eventos estresantes durante estos momentos. En los casos analizados, se observó ansiedad materna durante el embarazo y en el cuidado temprano del bebé. Sentimientos como el miedo, la angustia, las dudas y las preocupaciones, relatados por las madres, desencadenaron comportamientos ansiosos, reflejándose en la relación madre-bebé. A partir de los informes de este estudio se observa la importancia del apoyo para el empoderamiento de las madres, para que asuman ese rol con más confianza. Son necesarias intervenciones desde el embarazo para el tratamiento de la ansiedad materna, así como prácticas de educación con la finalidad de promoción de la salud mental materna y infantil.


Subject(s)
Humans , Female , Adult , Anxiety , Pregnancy Complications , Therapeutics , Behavior , Health Education , Parturition , Postpartum Period , Mother-Child Relations
6.
Rev. SPAGESP ; 22(1): 22-38, ene.-jun. 2021. ilus
Article in Portuguese | LILACS, Index Psychology - Scientific journals | ID: biblio-1155512

ABSTRACT

Objetivou-se compreender os procedimentos de recebimento e encaminhamento de notificações de casos de violência sexual realizados por conselheiros tutelares. Para isso, foram realizadas 10 entrevistas semiestruturadas com conselheiros/as tutelares de duas cidades do norte do Rio Grande do Sul. Os resultados indicaram pouca clareza na definição de violência sexual e de notificação. Foram consideradas notificações exitosas aquelas em que há informações de identificação de prováveis vítimas e agressores/as, enquanto as notificações não exitosas possuem poucas informações desses. Referente aos encaminhamentos, observou-se que há êxito quando os serviços da rede dialogam e se articulam e não êxito quando aspectos burocráticos predominam. Buscando uma melhoria no recebimento e nos encaminhamentos das notificações sobre violência sexual faz-se necessária a formação continuada por meio de capacitações, bem como a construção de fluxogramas para o efetivo trabalho.


We aim to understand the procedures of receiving and forwarding notifications of cases involving sexual violence against children performed by Child Protective Services (CPS). We carried out 10 semi-structured interviews with counselors from two cities of Rio Grande do Sul (a southernmost state in Brazil). The main results indicated little accuracy in defining sexual violence and notification. Successful notifications were those in which there is information that could identify victims and perpetrators. Unsuccessful notifications usually contain little information. Counselors observed successful outcomes in forwarding notifications when the services of the system dialogue and articulate, and unsuccessful ones when bureaucratic aspects predominate. We conclude it is necessary to invest in continuing education through capacitation, as well as constructing flowcharts for effective work in CPS.


El objetivo fue comprender los procedimientos para recibir y reenviar notificaciones de casos de violencia sexual realizados por Consejos Tutelares (CT). Fueron hechas 10 entrevistas semiestructuradas con 10 consejeros tutelares de dos ciudades de Rio Grande do Sul. Los resultados indicaron poca claridad en la definición de violencia sexual y notificación. Las notificaciones exitosas son las que incluyen informaciones que permiten identificar posibles víctimas y agresores. Las notificaciones no exitosas contienen pocas informaciones. Se observó que hay éxito en las derivaciones cuando los servicios de la red dialogan y se articulan y no éxito cuando prevalecen los aspectos burocráticos. La formación continua a través de capacitaciones es necesaria, así como la construcción de diagramas de flujo para el trabajo efectivo del CT.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Referral and Consultation , Sex Offenses , Counseling , Notification , Education, Continuing , Child Protective Services , Counselors , Child Advocacy
7.
Neoreviews ; 22(5): e284-e295, 2021 05.
Article in English | MEDLINE | ID: mdl-33931474

ABSTRACT

The coronavirus disease 2019 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has swept across the world like an indiscriminating wildfire. Pregnant women and neonates are particularly vulnerable to this infection compared with older children and healthy young adults, with unique challenges in their management. Unfamiliarity with the consequences of this novel virus and lack of high-quality data led to considerable heterogeneity in obstetrical and neonatal management early in the pandemic. The aim of the this review is to summarize the impact of SARS-CoV-2 infection on pregnancy and childbirth and to examine care and possible outcomes for neonates with Covid-19-positive mothers. A brief review of vaccines currently approved by the United States Food and Drug Administration for emergency use and their potential effects on pregnant and lactating women in included.


Subject(s)
/administration & dosage , Infant, Newborn, Diseases , Infectious Disease Transmission, Vertical/prevention & control , Pregnancy Complications, Infectious , Adult , /prevention & control , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/prevention & control , Infant, Newborn, Diseases/therapy , Pregnancy , Pregnancy Complications, Infectious/drug therapy , Pregnancy Complications, Infectious/prevention & control , Systemic Inflammatory Response Syndrome/drug therapy
8.
Tumour Biol ; 43(1): 27-35, 2021.
Article in English | MEDLINE | ID: mdl-33935123

ABSTRACT

OBJECTIVES: Genetic susceptibility to cervical cancer in relation to transforming growth factor beta 1 (TGFB1) gene polymorphisms has not been investigated extensively among the women in Bangladesh. So, the aim of this study was to find out the correlation of the polymorphisms of TGFB1 C509T (rs1800469) and T869C (rs1800470) with the risk of cervical cancer among the Bangladeshi women. STUDY DESIGN: 134 cervical cancer patients and 102 age-sex matched healthy controls were included from two institutions in Bangladesh. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was used for genotyping two TGFB1 single nucleotide polymorphisms C509T (rs1800469) and T869C (rs1800470) in patients and controls. RESULTS: No significant correlation was found between polymorphisms C509T (rs1800469) and T869C (rs1800470) of TGFB1 gene with cervical cancer in Bangladeshi women. In case of the cervical cancer patients who had first degree relatives with cancer were prone to carry the polymorphic version of the TGFB1 gene polymorphism at C509T (OR = 5.597, 95% CI = 1.224-25.597, p < 0.05) but may not result in the increase of developing cervical cancer. CONCLUSION: In summary, two polymorphisms C509T and T869C of TGFB1 gene may not be associated with cervical cancer risk in Bangladeshi women.


Subject(s)
Polymorphism, Single Nucleotide , Transforming Growth Factor beta1/genetics , Uterine Cervical Neoplasms/genetics , Adult , Bangladesh/epidemiology , Case-Control Studies , Female , Gene Frequency , Genetic Association Studies , Genotype , Humans , Middle Aged , Uterine Cervical Neoplasms/epidemiology , Uterine Cervical Neoplasms/pathology
9.
Tumour Biol ; 43(1): 57-70, 2021.
Article in English | MEDLINE | ID: mdl-33935125

ABSTRACT

OBJECTIVES: The tumor stage represents the single most important prognostic factor for colorectal cancer (CRC), although more accurate prognostics remain much needed. Previously, we identified CA125 as an independent significant prognostic factor, which we have further validated along with CEA, CA19-9, and CA242 in a large cohort of CRC patients. METHODS: Using enzyme-linked immunosorbent assays, we analyzed preoperative serum samples in 322 CRC patients operated on between 1998 and 2003. RESULTS: Using the Spearman's rho model, we calculated the correlation between our previous findings on MUC16 and CA125, for which the correlation coefficient was 0.808 (p < 0.001). The Cox regression analysis of the linear and logarithmic values of CEA, CA125, CA242, and CA19-9 identified only CA125 (hazard ratio [HR] 1.03; 95% confidence interval [95% CI] 1.02-1.04; p < 0.001) as significant when using the linear values. Survival among CRC patients with a high CA125 level was poor compared with CRC patients with a low CA125 level (HR 2.48; 95% CI 1.68-3.65; p < 0.001). In subgroup analyses, patients with high CA125 levels and aged ≤67 or >67, with stage I-II or III-IV, and both colon and rectal cancer exhibited poor prognoses. In the multivariate analysis, we used clinical pathological variables in the model, where age, gender, and stage served as the background characteristics. We dichotomized CA125 using the Youden maximal cutoff point, and the median values for CEA, CA19-9, and CA242. CA125 emerged as the only marker remaining significant and independent together with stage, location, and age (HR 1.91; 95% CI 1.24-2.95; p 0.003). CONCLUSIONS: CA125 represents a significant and independent prognostic factor in CRC patients, superior to CEA. Furthermore, CA242 served as a better prognostic marker than both CEA and CA19-9. We recommend including both CA125 and CA242 in prognostic clinical trials among CRC patients.


Subject(s)
Antigens, Tumor-Associated, Carbohydrate/blood , CA-125 Antigen/blood , Carcinoembryonic Antigen/blood , Colorectal Neoplasms/blood , Membrane Proteins/blood , Adult , Aged , Aged, 80 and over , Biomarkers, Tumor/blood , Cohort Studies , Colorectal Neoplasms/pathology , Colorectal Neoplasms/surgery , Female , Humans , Male , Middle Aged , Preoperative Period , Prognosis , Proportional Hazards Models , Survival Analysis
10.
J Psychiatr Pract ; 27(3): 172-183, 2021 05 05.
Article in English | MEDLINE | ID: mdl-33939371

ABSTRACT

The coronavirus disease 2019 (COVID-19) pandemic presented unprecedented challenges to the provision of inpatient psychiatric care. The nature of the physical plant, programmatic constraints, and the patient population required a rapid and agile approach to problem-solving under conditions of uncertainty and stress. Flexibility in decision-making, excellent communication, an effective working relationship with infection prevention and control experts, and attention to staff morale and support were important elements of successful provision of care to our inpatients. We present our experience, lessons learned, and recommendations should a resurgence of the pandemic or a similar crisis occur.


Subject(s)
Attitude of Health Personnel , Inpatients , Mental Disorders/therapy , Personnel, Hospital , Psychiatric Department, Hospital , Adult , Humans , Personnel, Hospital/psychology , Personnel, Hospital/standards , Psychiatric Department, Hospital/organization & administration , Psychiatric Department, Hospital/standards
11.
J Korean Med Sci ; 36(17): e114, 2021 May 03.
Article in English | MEDLINE | ID: mdl-33942578

ABSTRACT

BACKGROUND: Vaccination against coronavirus disease 2019 (COVID-19) is underway globally to prevent the infection caused by the severe acute respiratory syndrome coronavirus 2. We aimed to investigate the adverse events following immunization (AEFIs) for COVID-19 among healthcare workers (HCWs). METHODS: This was a retrospective study of the AEFIs associated with the first dose of the ChAdOx1 nCoV-19 vaccine at the Kosin University Gospel Hospital from March 3 to March 22, 2021. We investigated the systemic and local adverse events during the 7 days following the vaccination using the Mobile Vaccine Adverse Events Reporting System (MVAERS) developed by our hospital. RESULTS: A total of 1,503 HCWs were vaccinated, and the data of 994 HCWs were reported in the MVAERS. The most commonly reported AEFIs were tenderness at the injection site (94.5%), fatigue (92.9%), pain at the injection site (88.0%), and malaise (83.8%). The severity of most AEFIs was mild-to-moderate, and the severity and number of AEFIs were less in the older age group. There were no serious events requiring hospitalization, and most AEFIs improved within a few days. CONCLUSION: The AEFIs associated with the ChAdOx1 nCoV-19 vaccine were tolerable, and the use of the MVAERS was helpful in monitoring the AEFIs. The use of MVAERS will help in sharing accurate and ample information about vaccination against COVID-19.


Subject(s)
/adverse effects , /immunology , Vaccination/adverse effects , Adult , Adverse Drug Reaction Reporting Systems , Age Factors , Female , Health Personnel , Humans , Male , Middle Aged , Retrospective Studies
12.
J Korean Med Sci ; 36(17): e115, 2021 May 03.
Article in English | MEDLINE | ID: mdl-33942579

ABSTRACT

BACKGROUND: We performed a prospective survey on the adverse reactions following the first dose of two types of vaccines against coronavirus disease 2019 (COVID-19) in healthcare workers (HCWs) in South Korea. METHODS: HCWs at a tertiary referral hospital in Seoul, South Korea, received a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) or an mRNA-based vaccine (BNT162b2) between March 5 and March 26, 2021. The HCWs were asked to report adverse reactions through a mobile self-report questionnaire for three days after vaccination. RESULTS: A total of 7,625 HCWs received the first dose of ChAdOx1 or BNT162b2 vaccine during the study period. Of them, 5,866 (76.9%) HCWs (ChAdOx1, n = 5,589 [95.3%]; BNT162b2, n = 277 [4.7%]) participated at least once in the survey, of whom 77% were female and 86% were younger than 50 years. The overall adverse reaction rate was 93% in the ChAdOx1 group and 80% in the BNT162b2 group (P < 0.001). Both local and systemic reactions were more commonly reported in the ChAdOx1 group, and the difference was larger in systemic reactions such as fever and fatigue. In the ChAdOx1 group, the incidence of adverse reactions was significantly higher in females and those in the younger age groups, while the BNT162b2 group showed such difference according to age. CONCLUSION: In our prospective survey, vaccine-associated adverse reactions were more commonly reported in the ChAdOx1 group than in the BNT162b2 group. Females and younger age groups experienced vaccine-associated adverse reactions more frequently.


Subject(s)
/adverse effects , /immunology , Adult , Age Factors , Aged , Female , Health Personnel , Humans , Male , Middle Aged , Prospective Studies , Sex Characteristics , Young Adult
13.
JMIR Mhealth Uhealth ; 9(5): e25895, 2021 05 06.
Article in English | MEDLINE | ID: mdl-33955844

ABSTRACT

BACKGROUND: Melanoma is attributable to predisposing phenotypical factors, such as skin that easily sunburns and unprotected exposure to carcinogenic UV radiation. Reducing the proportion of young adults who get sunburned may reduce the incidence of melanoma, a deadly form of skin cancer. Advances in technology have enabled the delivery of real-time UV light exposure and content-relevant health interventions. OBJECTIVE: This study aims to examine the feasibility of young adults performing the following tasks daily: wearing a UV dosimeter, receiving text messages and real-time UV-B doses on their smartphone, and responding to daily web-based surveys about sunburn and sun protection. METHODS: Young adults aged 18-39 years (n=42) were recruited in the United States in June 2020 via social media. Participants received the UV Guard sun protection system, which consisted of a UV dosimeter and a smartphone app. During 3 consecutive periods, intervention intensity increased as follows: real-time UV-B dose; UV-B dose and daily behavioral facilitation text messages; and UV-B dose, goal setting, and daily text messages to support self-efficacy and self-regulation. Data were self-reported through daily web-based surveys for 28 days, and UV-B doses were transmitted to cloud-based storage. RESULTS: Patients' median age was 22 years (IQR 20, 29), and all patients had sun-sensitive skin. Sunburns were experienced during the study by fewer subjects (n=18) than those in the preceding 28 days (n=30). In July and August, the face was the most commonly sunburned area among 13 body locations; 52% (22/42) of sunburns occurred before the study and 45% (19/42) occurred during the study. The mean daily UV-B dose decreased during the 3 periods; however, this was not statistically significant. Young adults were most often exercising outdoors from 2 to 6 PM, walking from 10 AM to 6 PM, and relaxing from noon to 2 PM. Sunburn was most often experienced during exercise (odds ratio [OR] 5.65, 95% CI 1.60-6.10) and relaxation (OR 3.69, 95% CI 1.03-4.67) relative to those that did not exercise or relax in each category. The self-reported exit survey indicated that participants felt that they spent less time outdoors this summer compared to the last summer because of the COVID-19 pandemic and work. In addition, 38% (16/42) of the participants changed their use of sun protection based on their app-reported UV exposure, and 48% (20/42) shifted the time they went outside to periods with less-intense UV exposure. A total of 79% (33/42) of the participants were willing to continue using the UV Guard system outside of a research setting. CONCLUSIONS: In this proof-of-concept research, young adults demonstrated that they used the UV Guard system; however, optimization was needed. Although some sun protection behaviors changed, sunburn was not prevented in all participants, especially during outdoor exercise. TRIAL REGISTRATION: ClinicalTrials.gov NCT03344796; http://clinicaltrials.gov/ct2/show/NCT03344796.


Subject(s)
Sunburn , Adolescent , Adult , Health Behavior , Humans , Pandemics , Prospective Studies , Sunburn/drug therapy , Sunburn/epidemiology , Sunburn/prevention & control , Sunscreening Agents/therapeutic use , Ultraviolet Rays/adverse effects , United States , Young Adult
14.
Dtsch Arztebl Int ; 118(9): 145-151, 2021 03 05.
Article in English | MEDLINE | ID: mdl-33958032

ABSTRACT

BACKGROUND: The SARS-CoV-2 pandemic presented major challenges to the health sector in 2020. The burden of disease arising from COVID-19 can be expressed as the number of years of life lost to disease or death. For example, death at age 40 involves a loss of far more years of life than death at age 80. METHODS: The disability-adjusted life years (DALY) lost to COVID-19 were calculated as the sum of the years of life lost through death (YLL) and the number of years lived with disability (YLD), on the basis of laboratory-confirmed notifiable cases of SARS-CoV-2 infection in Germany in 2020 (documented as of 18 January 2021). The methodology was based on that used in the Global Burden of Disease Study. Pre-existing diseases do not enter into the determination of YLL; rather, the residual life expectancy that is applied in this calculation corresponds to a mean age-specific level of morbidity. RESULTS: 305 641 years of life were lost to COVID-19 in Germany in 2020. The percentage of DALY lost by persons under 70 was 34.8% in men and 21.0% in women. 99.3% of the COVID-19 disease burden was accounted for by death (YLL). The daily average years of life lost due to death was lower for COVID-19 than for the major non-communicable diseases. Persons who died of COVID-19 lost a mean of 9.6 years of life; those who were under 70 when they died lost a mean of 25.2 years of life. Men lost more years of life than women (11.0 vs. 8.1 years). CONCLUSION: The effects of COVID-19 on public health can be expressed through the burden of disease indicators. This method yields additional information that should be put to use early in the course of future outbreaks.


Subject(s)
Disabled Persons , Adult , Aged, 80 and over , Cost of Illness , Female , Germany/epidemiology , Humans , Male , Quality-Adjusted Life Years
15.
Urologiia ; (2): 14-20, 2021 May.
Article in Russian | MEDLINE | ID: mdl-33960151

ABSTRACT

AIM: To present the technical features and results of intestinal and appendicular ureteral replacement. MATERIAL AND METHODS: From 1998 to 2020, a total of 196 patients aged 18 to 77 years (mean age 49.5 +/- 1.2 years) were undergone to intestinal and appendicular ureteral reconstruction in our clinic. There were 123 women (62.8%). The most frequent indications for surgery were complications of open and endoscopic ureteral procedures, radiation-induced ureteral stricture, and iatrogenic injuries of the ureters during gynecological and surgical interventions (81.6%). In 165 (84.2%) patients, for ureteral replacement the ileal segment was used, while in 4 (2.0%) and 27 (13.8%) cases the colon segment and the appendix were chosen, respectively. Unilateral ileal ureteral replacement was performed in 131 (79.4%) cases, while in 34 (26.6%) patients a bilateral procedure was done. Partial and complete ureteral replacement was performed in 107 (81.7%) and 24 (18.3%) cases, respectively. Laparoscopic intestinal and appendicular ureteral replacement was performed in 44 (22.4%) patients, while two patients were undergone to robot-assisted procedure (1.0%). RESULTS: Early postoperative complications were noted in 17 (8.7%) cases. The most severe included acute bowel obstruction, leakage of entero-ureteral anastomoses, necrosis of the ileal graft and bleeding in 10 (5.1%) patients. In all cases, repeat intervention was performed. There were no lethal complications. Late postoperative complications developed in 24 (14.3%) patients. CONCLUSION: Today our clinic has the worlds largest experience in intestinal and appendicular ureteral reconstruction, including original procedures, confirmed by 5 patents for inventions. The minimum number of postoperative complications, the absence of deaths and good long-term results provide the basis for the introduction of ileal and appendicular ureteral replacement into clinical practice.


Subject(s)
Appendix , Reconstructive Surgical Procedures , Ureter , Ureteral Obstruction , Adolescent , Adult , Aged , Appendix/surgery , Female , Humans , Ileum/surgery , Male , Middle Aged , Ureter/surgery , Ureteral Obstruction/etiology , Ureteral Obstruction/surgery , Young Adult
16.
Acta Chir Orthop Traumatol Cech ; 88(2): 137-143, 2021.
Article in Czech | MEDLINE | ID: mdl-33960927

ABSTRACT

PURPOSE OF THE STUDY The Minimally Invasive Chevron Akin (MICA) is a percutaneous technique used to correct hallux valgus deformity. The combination of distal osteotomy of the first metatarsal and the proximal phalanx of the big toe stabilized with internal fixation was used over the last decade. The retrospective study presents the results of measurements performed on preoperative and postoperative X-rays and offers a comparison with conventional osteotomies. MATERIAL AND METHODS The study population consists of 76 patients who underwent 93 operations between 2015 and 2018 at the Department of Orthopaedics, 1st Faculty of Medicine, Charles University in Prague. The mean age of patients was 50.2 years (range 18-74 years). The study evaluates and measures the parameters and the attributes of interest on weight-bearing X-rays of the foot before and after the operation at 6-week or 3-month follow-ups. The first intermetatarsal angle was measured according to the mechanical and the anatomic axis of the first metatarsal bone. Apart from that, the displacement of the first metatarsal head in the osteotomy, hallux valgus angle and distal metatarsal articular angle were analysed. The position of the medial sesamoid bone and the congruency of the first metatarsophalangeal joint were evaluated as well. RESULTS The mean hallux valgus angle was 33.2° ± 7.3° and 10.2° ± 5.8° postoperatively. The mean value of the first mechanical intermetatarsal angle decreased from 12.4° ± 2.8° to 7.4° ± 2.5° postoperatively. The mean value of the first anatomic intermetatarsal angle increased from 13.7° ± 3.6° to 17.4° ± 4.6°. The used technique restored the congruency of the first metatarsophalangeal joint in 85 cases (91%). The mean lateral displacement of the metatarsal head fragment was 50% of its width (range 18% to 84%). The mean X-ray exposure during the operation was 0.58 mGy and the personnel were exposed to radiation for 79 seconds on average. DISCUSSION One of many questions raised with regard to hallux valgus surgery is the choice of the right technique in order to achieve proper position of the big toe. The surgeon should have the opportunity to use a technique that provides the possibility to change orientation of the metatarsal head articular surface in three anatomic planes. Our study found out that the displacement of the metatarsal head using the MICA technique in transversal plane is from 4 mm to 18 mm (in 20 mm diameter of the head). The method thus offers a possibility to correct mild, moderate and partially severe deformities as well. The main disadvantage of the method is the necessity to use a C-arm at the operating theatre. CONCLUSIONS The Minimally Invasive Chevron Akin (MICA) is a percutaneous technique to correct hallux valgus deformity based on two extraarticular osteotomies of the proximal phalanx of the big toe and the distal part of the first metatarsal bone. The method using stable internal fixation with two screws offers a possibility to change the orientation of the articular surface of the metatarsal head in sagittal, transversal, and even in frontal plane, and is useful to correct mild and moderate deformities. Key words: hallux valgus, minimally invasive technique, percutaneous technique, chevron osteotomy, Akin osteotomy.


Subject(s)
Bunion , Hallux Valgus , Metatarsal Bones , Metatarsophalangeal Joint , Adolescent , Adult , Aged , Hallux Valgus/diagnostic imaging , Hallux Valgus/surgery , Humans , Metatarsal Bones/diagnostic imaging , Metatarsal Bones/surgery , Middle Aged , Retrospective Studies , Treatment Outcome , Young Adult
17.
Soins ; 66(854): 43-45, 2021 Apr.
Article in French | MEDLINE | ID: mdl-33962732

ABSTRACT

A bone marrow transplant is often the only hope for a cure for some patients with blood disease. Beyond its medical aspects, it underlies psychological issues for both the recipient and the donor. The transplant brings together the issues of donation, debt, the family romance and the incorporation of a "foreign body", evoking the classic notion of chimera.


Subject(s)
Bone Marrow Transplantation , Hematopoietic Stem Cell Transplantation , Adult , Humans , Tissue Donors
18.
Georgian Med News ; (312): 46-52, 2021 Mar.
Article in Russian | MEDLINE | ID: mdl-33964825

ABSTRACT

Objective - to determine the features of the daily profile of blood pressure (BP), blood lipid spectrum, features of left ventricular remodeling in patients with hypertension in combination with RA and to evaluate the effectiveness of using medium doses of rosuvastatin to correct dyslipidemia in this group of patients. 70 patients aged 40-65 years were examined (average - M±m - 54.88±0.96 years). Hypertensive disease in combination with rheumatoid arthritis was found in 50 patients, which made up the main group. The patients were divided into 2 subgroups: the first group included 25 patients with essential hypertension in combination with rheumatoid arthritis, who took valsartan at a dose of 80 mg at home, indapamide 1.5 mg, rosuvastatin 20 mg. The second subgroup included 25 patients who took valsartan at a dose of 80 mg / day, amlodipine at a dose of 5 mg, rosuvastatin at a dose of 20 mg. The control group (comparison) consisted of 20 patients with arterial hypertension without RA, matched by sex and age with the main groups. (3 people, 17 women, average age 55.65±1.19 years). 1. Valsartan therapy and its combination with indapamide in hypertensive patients in combination with rheumatoid arthritis led to regression of LVH in all patients, normalization of LV geometry in 33% of patients, improvement of LV diastolic function in 88.2%. 2. The addition of indapamide to therapy led to a further decrease in the average values of blood pressure at night, increased the number of patients who achieved normalization of blood pressure from 50 to 75%, while therapy with amlodipine with indapamide did not change the severity of the circadian rhythm of blood pressure and the degree of nighttime decrease in SBP and in general the group remained inadequate. 3. Changes in the diurnal blood pressure profile, found in the majority of patients with arterial hypertension in combination with rheumatoid arthritis, were characterized by increased mean daily, mean systolic blood pressure levels, increased daytime variability, and a lower degree of nocturnal decrease in comparison with patients without RA. 4. The use of 20 mg rosuvastatin as part of complex therapy in patients with hypertension in combination with RA contributed to the achievement of target levels of lipid spectrum in the blood in most patients.ent of target levels of lipid spectrum in the blood in most patients.


Subject(s)
Arthritis, Rheumatoid , Atherosclerosis , Hypertension , Adult , Aged , Amlodipine/therapeutic use , Antihypertensive Agents/therapeutic use , Arthritis, Rheumatoid/complications , Arthritis, Rheumatoid/drug therapy , Blood Pressure , Blood Pressure Monitoring, Ambulatory , Female , Heart Ventricles , Humans , Hypertension/complications , Hypertension/drug therapy , Middle Aged
19.
Georgian Med News ; (312): 42-46, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33964824

ABSTRACT

In recent years, according to the WHO, more than 1,9 billion people over the age of 18 are overweight, of whom more than 650 million are obese, with an annual trend. Studies in recent decades have shown that obese young people with generalized periodontitis have abnormalities in protein, fat and carbohydrate metabolism, which contributes to the early destruction of the periodontal tissue complex and rapid tooth loss. The aim of our study was to examine changes in serum leptin and adiponectin in patients with generalized periodontitis on the background of obesity. The study involved 94 people aged 19 to 35 years. Patients were divided into 3 groups: 32 patients with generalized periodontitis on the background of overweight, 40 patients with generalized periodontitis and obesity, and the control group - 22 healthy individuals of the same age category. The content of leptin and adiponectin in the serum was determined by enzyme-linked immunosorbent assay (ELISA) ELISA. The study was performed by analyzing venous blood (2 ml) in a BD Vacutainer tube and then centrifuging on LDN and Mediagnost GmbH analyzers and test systems (Germany). Studies allow us to conclude that in the serum of patients with generalized periodontitis on the background of overweight and obesity there is an imbalance of adipokines leptin and adiponectin. The obtained data are consistent with the literature, according to which, an increase in BMI is accompanied by an increase in leptin production and a decrease in adiponectin levels. These disorders were more pronounced in patients with generalized periodontitis on the background of obesity. Such an imbalance in adipose tissue may stimulate the production of pro-inflammatory cytokines and contribute to the progression of periodontal disease in such patients.


Subject(s)
Leptin , Periodontitis , Adipokines , Adiponectin , Adolescent , Adult , Germany , Humans , Middle Aged , Obesity/complications , Periodontitis/complications , Young Adult
20.
Georgian Med News ; (312): 82-87, 2021 Mar.
Article in Russian | MEDLINE | ID: mdl-33964833

ABSTRACT

The purpose of this review is study of literature for the development of biological effect of Kalcipherol (D vitamin group) on children population. Different factors seem, that D- vitamin deficiency disbalance elevated, children specifically negative effect, which have a major impact on health, growth and development of infants, children and adolescents. Vitamin D and calcium deficiencies are preventable global public health problems in pediatric medicine. The laboratory assessment of vitamin D (calcidiol-25(OH)D), epidemiological studies assessing the prevalence of vitamin D deficiency, are performed to analyze the relationships between neuropsychological function and mechanisms of toxic effects in the setting of vitamin D.


Subject(s)
Vitamin D Deficiency , Adolescent , Adult , Child , Humans , Infant , Prevalence , Vitamin D , Vitamin D Deficiency/epidemiology , Vitamins
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