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1.
Article in English | MEDLINE | ID: mdl-35897443

ABSTRACT

It is known that the sharp change of air pollutants affects air quality. Chinese Spring Festival is the most important holiday for Chinese people, and the celebration of the holiday with fireworks and the movement of people all around the country results in significant change in multiple air pollutant emissions of various sources. As many cities and rural areas suffer from the air pollution caused by firework displays and more residential fuel consumption, there is an urgency to examine the impact of the Chinese Spring Festival on air quality. Hence, this paper firstly gives an overall insight into the holiday's impact on ambient and household air quality in China, both in urban and rural areas. The main findings of this study are: (1) The firework displays affect the air quality of urban and rural atmosphere and household air; (2) the reduction in anthropogenic emissions improves the air quality during the Chinese Spring Festival; (3) the household air in urban areas was affected most by firework burning, while the household air in rural homes was affected most by fuel consumption; and (4) the short-term health impact of air pollution during the holidays also need more concern. Although there have been many publications focused on the holiday's impact on ambient and household air quality, most of them focused on the measurement of pollutant concentration, while studies on the formation mechanism of air pollution, the influence of meteorological conditions, and the health outcome under the effect of the Chinese Spring Festival are rare. In the future, studies focused on these processes are welcomed.


Subject(s)
Air Pollutants , Air Pollution , Air Pollutants/analysis , China , Environmental Monitoring , Holidays , Humans , Particulate Matter/analysis , Seasons
2.
Article in English | MEDLINE | ID: mdl-35886167

ABSTRACT

Travelling families are interested in urban tourism due to its cognitive and entertainment aspects. Some expectations of parents travelling with children are the same independent of the accommodation location. The purpose of this article is to examine at what level city hotels offer services and amenities within family tourism, how they meet parents' expectations and whether they adapt offers to children of different ages. Two measurement tools were used for this study. The first one was the authors' questionnaire addressed to hotel managers. A total of 88 hotels located in Krakow were selected for the study. The survey contained questions on the offers of hotels related to various services and amenities for families with children, which were assigned to one of three groups (24 items): general child-friendly hotel services and amenities, in-room amenities and restaurant amenities. In the second phase of the study, parents of children aged 0-10 years were asked to assess the degree to which the amenities offered by hotels were important for them during the selection of a hotel. In total, 90 surveys were taken into consideration. The tool was designed to examine the needs of parents who have children of different ages, in regard to selected hotel services and amenities (24 items). As in the case of the surveys for hoteliers, the same three groups were created. The research demonstrates that children's age is the key factor that should lead to the differentiation of the accommodation offer. However, hoteliers largely perceive children as a homogeneous group. In all studied age categories (6) and amenities groups (3), parents' expectations were higher than the services and amenities offered. No significant differences regarding the category of the hotel or hotel chain membership have been found. The results of the study may provide valuable guidance to hoteliers who wish to attract families with children to urban tourism and adapt their offer to them, thus realising the principle of inclusiveness. They may be also a significant contribution to the literature on the subject, as most published work concerns holiday hotels rather than city hotels.


Subject(s)
Tourism , Travel , Cities , Family , Holidays , Humans
3.
Front Endocrinol (Lausanne) ; 13: 915482, 2022.
Article in English | MEDLINE | ID: mdl-35837316

ABSTRACT

Aims: There is limited evidence that evaluates the glycemic control of type 1 diabetes mellitus (T1DM) during the Chinese New Year public holiday in China. The Chinese New Year public holiday represents various challenges to glycemic control, especially in T1DM patients, in China. We aimed to assess the effect of the Chinese New Year public holiday on several glucose metrics using flash glucose monitoring (FGM) in patients with T1DM. Methods: Complete FGM data for 1 week before, 1 week during and 1 week after the Chinese New Year public holiday were available for 71 T1DM patients treated with multiple daily insulin injection (MDI) therapy (n = 51) or continuous subcutaneous insulin infusion (CSII) treatment (n = 20). The mean age of the study participants was 13 (9, 30) years. Of note, 59.2% of the patients (n = 42) were adults, and 40.8% of the patients (n = 29) were minors. The interval between each two adjacent periods was one week. The indicators of mean glucose, glucose variability and time in different glycemic ranges were analyzed. Results: The Chinese New Year public holiday was associated with an increase in mean blood glucose (8.4 ± 1.7 vs. 9.2 ± 2.5; P < 0.001) and time above range (TAR) (27.9% ± 16.6% vs. 35.0% ± 22.3%; P< 0.001) but a decrease in time in range (TIR) (65.1% ± 15.5% vs. 58.0% ± 19.0%; P < 0.001) and coefficient of variation (CV) (65.1% ± 15.5% vs. 58.0% ± 19.0%; P < 0.001). There was no significant difference in time below range (TBR). The glycemic control deteriorated during the Chinese New Year public holiday in our study population regardless of age. Interestingly, in the CSII group, none of the metrics of glucose control significantly changed during the Chinese New Year public holiday. Conclusions: These results suggested that less self-management may worsen glycemic control in the short term, indicating a need for more refined management algorithms during the Chinese New Year public holiday for T1DM patients.


Subject(s)
Diabetes Mellitus, Type 1 , Adult , Blood Glucose , Blood Glucose Self-Monitoring/methods , Diabetes Mellitus, Type 1/drug therapy , Glucose , Glycated Hemoglobin A/analysis , Glycemic Control , Holidays , Humans , Hypoglycemic Agents/adverse effects , Insulin , Insulin Infusion Systems
5.
J Environ Manage ; 317: 115459, 2022 Sep 01.
Article in English | MEDLINE | ID: mdl-35751297

ABSTRACT

Since the air pollution and noise generated from fireworks are related to air quality and human health, the regulatory bodies had implemented the eco-friendly "Green Crackers" in megacity Delhi, India, to celebrate Diwali 2019 with the permission of a specific time slot (8:00 p.m. to 10:00 p.m.). The present study was conducted on a residential educational institute campus to evaluate the particle number size distribution (PNSD) of green cracker emissions. During the Diwali event period, the high peak of particle number concentration (PNC) reached 1.7 × 105 # cm-3 with a geometric mean diameter (GMD) of ∼44 nm. The average PNC increment on Diwali day was 138% and 97% compared to pre (October 26, 2019) and post (October 28, 2019) Diwali period, respectively, including 468%, 142%, 65%, 75% on pre-Diwali and 485%, 110%, 32%, 26% on post- Diwali 2019 period in terms of Nucleation mode (10 nm < Dp < 20 nm), Small Aitken mode (20 nm < Dp < 50 nm), Large Aitken mode (50 nm < Dp < 100 nm), and Accumulation mode (100 nm < Dp < 1000 nm), respectively. Unlike traditional firework emissions, green crackers had a high UFP/Ntotal ratio of 0.72, including Nucleation mode-0.35, Aitken mode-0.30, and Accumulation mode 0.35, distinguishing it from other pre-and post-Diwali particle number size distribution-dN/dlogDp curves. These observations indicate that green crackers emit more particles with smaller diameters than traditional crackers. Recommendations for using green crackers for Diwali celebrations may be an option if lower size-diameter particle emission could be controlled by changing the material composition of the green crackers. More research studies need to be conducted to assess atmospheric emissions of green crackers and their health impacts to evaluate whether they are better or worse than traditional crackers.


Subject(s)
Air Pollutants , Air Pollution , Air Pollutants/analysis , Air Pollution/analysis , Environmental Monitoring , Holidays , Humans , India , Particle Size , Particulate Matter/analysis
6.
Pharmacogenomics ; 23(9): 509-511, 2022 06.
Article in English | MEDLINE | ID: mdl-35670264

ABSTRACT

Implementation of personalized medicine in the clinic is a lengthy and multifaceted approach that is also dependent on the raising of the general public's awareness of genomics. The Festival of Genetics and Personalized Medicine aims to familiarize the general public with the principles and applications of genetics and personalized medicine using numerous approaches - namely, a theatrical performance; a roundtable discussion of emerging topics in the field, such as pharmacogenomics, clinical genetics, bioinformatics, bioethics and health economics; the 'Genome: Unlocking Life's Code' exhibition, with its do-it-yourself format; and a live demonstration of 2MoBiL, a portable molecular biology laboratory. This festival attracted more than 900 participants and helped disseminate to a broader audience the principles of genetics and personalized medicine.


Subject(s)
Holidays , Precision Medicine , Computational Biology , Genomics , Humans , Pharmacogenetics
7.
Article in English | MEDLINE | ID: mdl-35627511

ABSTRACT

Digital-free tourism (DFT) has recently attracted tourism service providers' attention for its benefits in terms of enhancing tourists' experiences and well-being at destinations. DFT refers to tourists who are likely to voluntarily avoid digital devices and the Internet on holiday, or travel to destinations without network signals. DFT has advantages for tourists in increasing well-being, mental health, and social networking during their journeys. DFT also has a benefit for tourism marketers in that they can consider it as a new tourism approach. However, there is a lack of studies into tourists' locus of control (LOC) while experiencing DFT holidays. LOC refers to how individuals assign the responsibility of event outcomes-whether they assign it to themselves (internal LOC) or they say it is beyond their control (external LOC). Therefore, the current study contributes to investigating tourists' LOC impacts while experiencing DFT holidays. The study relies on semi-structured interviews with millennial tourists who have experienced DFT holidays. The study findings reveal that millennial tourists with an internal LOC (vs. external) are more likely to perceive the DFT advantages (vs. obstacles) during and after the DFT holidays. However, millennial tourists with external LOC incrementally change their attitudes and perceive the DFT holiday benefits through their self-efficacy enhancement. The findings propose managerial strategies for developing effective DFT holidays for millennial tourists regarding their LOC.


Subject(s)
Medical Tourism , Tourism , Holidays , Humans , Travel
8.
Curr Pharm Des ; 28(15): 1245-1249, 2022.
Article in English | MEDLINE | ID: mdl-35585812

ABSTRACT

OBJECTIVE: New psychoactive substance use (NPS) is a reality in France, including among drivers. This work aims (i) to report the pharmaceutical design of NPS detected in oral fluid (OF) from drivers initially screened for drugs around a music festival in 2019 and (ii) to compare obtained results with those of a previous similar study carried out in 2017 in the same situation (and the same music festival) and according to the same methodology. METHODS: OF specimens were recovered from the user devices of the salivary immunochemical tests used by the police during the controls carried out at the entering and leaving the festival. These OF were analyzed using liquid chromatography coupled with tandem mass spectrometry and high-resolution mass spectrometry methods using mass spectra libraries of approximately 1700 substances, including (in 2020) more than 650 NPS and metabolites. RESULTS: NPS was detected in 14 out of the 265 collected OF specimens. Ten NPS were identified (number of identification): APINACA (1), AB-Chminaca (1), 5F-AMB (1), 5F-PB-22 (5), 2C-D (1), methoxetamine (2), ketamine (1), x-CMC (1), 4-MEC (2), ethylone (2). The prevalence of NPS detection in OF (5.2%) is in the same order as the observed one in 2017 (6.8%), but these results are marked by the majority and increasing proportion of synthetic cannabinoids (47% of identified NPS in 2019 vs. 25% in 2017), an increase also in the proportion of cathinone derivatives (29% in 2019 vs. 6% in 2017), and a decrease in cyclohexanones (17% in 2019 vs. 43% in 2017). CONCLUSION: These pharmaceutical design trends (2019 vs. 2017) observed in a population of drivers around a music festival seem to reflect those that can be seen in more general populations in France, with probably a rise in the consumption of synthetic cannabinoids.


Subject(s)
Cannabinoids , Music , Drug Design , Holidays , Humans , Psychotropic Drugs , Substance Abuse Detection/methods , Tandem Mass Spectrometry/methods
9.
San Salvador; MINSAL; abr. 21, 2022. 4 p. ilus, graf, tab.
Non-conventional in Spanish | LILACS, BISSAL | ID: biblio-1366980

ABSTRACT

Informe que presenta la situación epidemiológica El Salvador al 18 de abril de 2022 (Datos preliminares) Principales causas de consulta, acumuladas desde el 11 de abril a la fecha, años 2021 ­ 2022 Total consultas, emergencias y referencias, Semana Santa El Salvador 2020 ­ 2021 Informe de COVID-19 I. Contexto mundial de COVID -19 II. Contexto Centroamérica y República Dominicana III. Situación Nacional, Programación semanal de tamizajes comunitarios, semana santa 2022 Recursos Humanos a disposición para este periodo del sistema integrado de salud


Report presenting the epidemiological situation of El Salvador as of April 18, 2022 (Preliminary data) Main causes of consultation, accumulated from April 11 to date, years 2021 - 2022 Total queries, emergencies and referrals, Easter El Salvador 2020 ­ 2021 COVID-19 Report I. Global Context of COVID -19 II. Context Central America and the Dominican Republic III. National Situation, Weekly programming of community screening, Holy Week 2022 Human resources available for this period of the integrated health system


Subject(s)
Health , Epidemiology , Electronic Publications , Holidays , Infections , Mass Screening , El Salvador , Preliminary Data
10.
J Environ Sci (China) ; 114: 322-333, 2022 Apr.
Article in English | MEDLINE | ID: mdl-35459495

ABSTRACT

The impact of reducing industrial emissions of volatile organic compounds (VOCs) on ozone (O3) pollution is of wide concern particularly in highly industrialized megacities. In this study, O3, nitrogen oxides (NOx) and VOCs were measured at an urban site in the Pearl River Delta region during the 2018 Chinese National Day Holidays and two after-holiday periods (one with ozone pollution and another without). O3 pollution occurred throughout the 7-day holidays even industrial emissions of VOCs were passively reduced due to temporary factory shutdowns, and the toluene to benzene ratios dropped from ∼10 during non-holidays to ∼5 during the holidays. Box model (AtChem2-MCM) simulations with the input of observation data revealed that O3 formation was all VOC-limited, and alkenes had the highest relative incremental reactivity (RIR) during the holiday and non-holiday O3 episodes while aromatics had the highest RIR during the non-pollution period. Box model also demonstrated that even aromatics decreased proportionally to levels with near-zero contributions of industrial aromatic solvents, O3 concentrations would only decrease by less than 20% during the holiday and non-holiday O3 episodes and ozone pollution in the periods could not be eliminated. The results imply that controlling emissions of industrial aromatic solvents might be not enough to eliminate O3 pollution in the region, and more attention should be paid to anthropogenic reactive alkenes. Isoprene and formaldehyde were among the top 3 species by RIRs in all the three pollution and non-pollution periods, suggesting substantial contribution to O3 formation from biogenic VOCs.


Subject(s)
Air Pollutants , Ozone , Volatile Organic Compounds , Air Pollutants/analysis , Alkenes , China , Environmental Monitoring , Holidays , Ozone/analysis , Solvents , Volatile Organic Compounds/analysis
11.
Huan Jing Ke Xue ; 43(4): 1716-1724, 2022 Apr 08.
Article in Chinese | MEDLINE | ID: mdl-35393795

ABSTRACT

Water-soluble ions and some trace gases during the Spring Festival in Ningbo were observed using an ion online gas composition and aerosol monitoring system. Combined with meteorological elements data, the source analysis and composition characteristics of water-soluble ions and trace gases were analyzed. The average concentration of ρ(PM2.5) during the observation period was 33.1 µg·m-3, and there was light pollution. The order of concentration of water-soluble ions was NO3->SO42->NH4+>K+>Cl->Na+>Ca2+>Mg2+. The secondary inorganic ions ρ(NO3-), ρ(SO42-), and ρ(NH4+) were the most water-soluble ions, which were 12.5, 10.5, and 7.2 µg·m-3, respectively. According to the PMF source analysis, firecracker combustion, secondary generation (background, industrial source), and dust sources were the major sources of fine particles during the observation period, and their contribution rates of PM2.5 were 21.9%, 64.5%, and 13.6%, respectively. When the secondary generation was the main pollution, NH4+ accounted for 92.2% of the cations. When firecracker combustion was the main pollution from New Year's Eve to the second day, the proportion of K+ions significantly increased. Dust sources were affected by regional transport from the northwest direction. When the dust source was the main pollution, the proportion of K++Ca2+and Na++Mg2+ increased.


Subject(s)
Air Pollutants , Particulate Matter , Aerosols/analysis , Air Pollutants/analysis , Dust/analysis , Environmental Monitoring , Gases/analysis , Holidays , Ions/analysis , Particulate Matter/analysis , Seasons , Water/analysis
12.
Huan Jing Ke Xue ; 43(4): 1747-1755, 2022 Apr 08.
Article in Chinese | MEDLINE | ID: mdl-35393798

ABSTRACT

Volatile organic compounds (VOCs) are the key precursors of the ozone (O3) formation processes in the troposphere and are important control objects for the coordinated governance of O3 and PM2.5. The Spring Festival of 2020 was affected by the novel coronavirus (COVID-19) pneumonia epidemic:companies stopped work and production, and traffic was restricted, providing scientific experimentation opportunities for pollutant emission reduction research. This study analyzed the variety of the composition, chemical reaction activity, and sources of VOCs in the Pearl River Delta during the Spring Festival and the epidemic control period, using real-time online monitoring data of VOCs obtained at four sites(Guangzhou, Dongguan, Zhongshan, and Duanfen)in the Pearl River Delta from January 1, 2020 to February 29, 2020. The results showed that during the Spring Festival and the epidemic control period, the average of φ (VOCs) in the Pearl River Delta was 15.89×10-9, and the maximum hourly average concentration was 45.43×10-9, values that were 44% and 60% lower, respectively, than those before the Spring Festival holiday. Among the VOCs component concentration decreases, the aromatic hydrocarbon component decreased the most, and the decrease in the urban area of the Pearl River Delta (74%) was significantly greater than that in the suburban area (56%). As a result, the contribution rate of aromatic hydrocarbons to the total VOCs was reduced to less than 10%. The analysis of the·OH reaction activity of VOCs(L·OH)and ozone formation potential(OFP)showed that the L·OH and OFP of VOCs decreased significantly in the Pearl River Delta during the Spring Festival and the epidemic control period. Compared with those before the Spring Festival holiday, the total L·OH and total OFP decreased by an average of 60% and 63% in the urban area of the Pearl River Delta, respectively. Additionally, the atmospheric oxidation had also been significantly reduced, which showed a 28% decrease in ρ(Ox). The ratio of toluene/benzene showed that the influence of industrial sources had almost disappeared during the Spring Festival and the epidemic control period, and the total points of the representative components of industrial-related solvent-use sources such as toluene, ethylbenzene, and m/p-xylene dropped by 72% to 91%. The results of this study suggest that solvent-use sources and vehicle exhaust emission sources are the current sources of VOCs that need to be paid attention to in the prevention and control of O3 pollution in the Pearl River Delta region, and the impact of petrochemical sources cannot be ignored in the work of further reducing the background concentration of O3.


Subject(s)
Air Pollutants , COVID-19 , Ozone , Volatile Organic Compounds , Air Pollutants/analysis , COVID-19/epidemiology , COVID-19/prevention & control , China/epidemiology , Environmental Monitoring/methods , Holidays , Humans , Ozone/analysis , Solvents/analysis , Toluene/analysis , Vehicle Emissions/analysis , Volatile Organic Compounds/analysis
13.
Environ Pollut ; 303: 119122, 2022 Jun 15.
Article in English | MEDLINE | ID: mdl-35276248

ABSTRACT

Photochemical losses of volatile organic compounds (VOCs) and uncertainties in calculated factor profiles can reduce the accuracy of source apportionment by positive matrix factorization (PMF). We developed an improved PMF method (termed ICLP-PMF) that estimated the reaction-corrected ("initial") concentrations of VOCs. Source profiles from literature provided constraints. ICLP-PMF evaluated the vehicular emission contributions to hourly speciated VOC data from December 2020 to March 2021 and estimated gasoline and diesel vehicles contributions to Tianjin's VOC concentrations around the Chinese Spring Festival (SF). The average observed and initial total VOCs (TVOCs) concentrations were 24.2 and 42.9 ppbv, respectively. Alkanes were the highest concentration VOCs while aromatics showed the largest photochemical losses during the study period. Literature gasoline and diesel profiles from representative Chinese cities were constructed and provided constraints. Source apportionment was performed using ICLP-PMF method and three other PMF approaches. Photochemical losses of alkenes and aromatic hydrocarbons induced differences between calculated factor profiles and literature profiles. Using observed concentrations and unconstrained profiles produced underestimated SF contributions (∼121% and 72% for gasoline and diesel vehicles, respectively). According to the ICLP-PMF results, the contributions of gasoline and diesel vehicles during the SF were 25.6% and 23.2%, respectively, lower than those before and after the SF. No diel diesel vehicle contribution variations were found during the SF likely due to the decline in truck activity north of the study site during the holiday period.


Subject(s)
Air Pollutants , Volatile Organic Compounds , Air Pollutants/analysis , China , Environmental Monitoring/methods , Gasoline/analysis , Holidays , Vehicle Emissions/analysis , Volatile Organic Compounds/analysis
14.
J Pharm Biomed Anal ; 214: 114728, 2022 May 30.
Article in English | MEDLINE | ID: mdl-35349940

ABSTRACT

We describe a method validation for the quantification of 3,4-methylenedioxymethamphetamine (MDMA) in tablets based on the United Nations Office on Drugs and Crime (UNODC) guideline for quantitative Nuclear Magnetic Resonance analysis (qNMR). qNMR experiments were carried out on a 60 MHz benchtop NMR spectrometer employing ethylene carbonate as an internal calibrant. A series of 'ecstasy' tablets seized at music events were quantified and the results discussed regarding their within-batch variation and yearly median dose. The method showed good specificity and selectivity, with linearity, precision, accuracy, and recovery well within the UNODC recommended criteria. The limit of detection and quantification are 0.33 mg/mL and 0.10 mg/mL respectively, proving the method works well on small amounts of MDMA. Overall, the lowest amount of MDMA free base detected in this study was 9.35 mg in a piperazine mix, while the highest dosed tablet contained 237.55 mg MDMA free base, with a 9.1% decrease in median amount compared to the pre-pandemic data (2019), but still higher than the data collected in a previous study (105 mg median amount of MDMA free base in 2018). The within-batch variation was insignificant for one of the seizures but showed greater variation for the other, which confirmed that the MDMA content of a single tablet may not reflect that of the whole batch. This dynamic upward change in tablet dosage highlights the importance of ongoing trend monitoring and specific prevention intervention to counteract the negative consequences associated with MDMA use. Benchtop NMR has been successfully employed in quality control, material science and more recently, drug analysis. The present study demonstrates its beneficial application in forensic science overcoming the limitations of currently available instruments and techniques employed in harm reduction and field testing.


Subject(s)
Hallucinogens , Illicit Drugs , Music , N-Methyl-3,4-methylenedioxyamphetamine , Hallucinogens/analysis , Holidays , Illicit Drugs/analysis , Magnetic Resonance Spectroscopy , N-Methyl-3,4-methylenedioxyamphetamine/analysis , N-Methyl-3,4-methylenedioxyamphetamine/chemistry , Tablets/chemistry
15.
PLoS One ; 17(3): e0264507, 2022.
Article in English | MEDLINE | ID: mdl-35353827

ABSTRACT

Russian trolls generally supported the Trump campaign and were particularly active on Twitter 2015-2017. We find that trolling fell 35% on Russian holidays and to a lesser extent, when temperatures were cold in St. Petersburg. Exogenous variation in trolling by day allows us to consider indirectly-affected political behaviors in the US-outcomes that are less traceable via tweet sharing but potentially more important to policymakers than the direct dissemination previously studied. As a case in point, we describe reduced form evidence that Russian holidays affected daily trading prices in 2016 election betting markets. This response is consistent with successful Russian interference in support of Trump.


Subject(s)
Gambling , Holidays , Humans , Politics , Russia
16.
Jpn J Ophthalmol ; 66(3): 271-277, 2022 May.
Article in English | MEDLINE | ID: mdl-35306598

ABSTRACT

PURPOSE: To investigate the characteristics of retinal detachment (RD) and compare the outcomes of surgical interventions, such as scleral buckling (SB), pars plana vitrectomy (PPV), or PPV combined with SB, conducted on holidays and on workdays to determine the optimal surgical timing for primary RD treatment in clinical practice. STUDY DESIGN: Retrospective cohort study. METHODS: The cohort included 3178 patients with primary RD registered in the Japan Retinal Detachment Registry between February 2016 and March 2017. Surgery data were divided into holiday and workday groups. A descriptive analysis of primary RD characteristics was performed, and the outcomes for each surgical intervention were assessed. The primary outcome was anatomical failure at 6 months post-surgery classified as follows: level 1, inoperable state; level 2, anatomical recovery with silicone-oil use; and level 3, additional surgery required for RD repair. RESULTS: The holiday group comprised 108 and the workday, 3070 cases of primary RD. Compared with those in the workday group, surgery in the holiday group took longer (PPV, P < 0.0001; SB, P = 0.047) and was performed by less experienced surgeons (P = 0.014). However, there were no statistically significant differences in surgical failure 6 months post-surgery between the workday and holiday groups. CONCLUSION: Although surgery conducted on holidays and workdays was not significantly different in terms of outcome, some surgery should be postponed with proper preoperative interim measures to limit RD progress until it can be conducted on workdays by a well-prepared team.


Subject(s)
Retinal Detachment , Holidays , Humans , Japan/epidemiology , Registries , Retinal Detachment/surgery , Retrospective Studies , Scleral Buckling , Treatment Outcome , Visual Acuity , Vitrectomy
17.
Huan Jing Ke Xue ; 43(3): 1212-1225, 2022 Mar 08.
Article in Chinese | MEDLINE | ID: mdl-35258185

ABSTRACT

The PM2.5concentration characteristics of "2+26" cities in Beijing-Tianjin-Hebei and the surrounding region during the Spring Festival and the Lantern Festival in 2021 were analyzed. The average daily concentration and hourly concentration of PM2.5 in the three days before and after the Spring Festival and the Lantern Festival from 2016 to 2021 and the characteristics of the PM2.5 chemical components during the Spring Festival and the Lantern Festival from 2019 to 2021 were comparatively analyzed. In addition, the impact of meteorological factors on PM2.5 concentration from 2016 to 2021 and the key factors affecting the forecast result of Beijing during the Spring Festival in 2021 were discussed. The results showed that the combination of fireworks and firecrackers and adverse weather conditions resulted in a moderate to heavy pollution process during the Spring Festival in 2021 and a light to moderate pollution process during the Lantern Festival in "2+26" cities. The average ρ(PM2.5) was 111 µg·m-3. The hourly peak ρ(PM2.5) was 156 µg·m-3, which was the lowest in 2016 to 2021. The three days before and after the Lantern Festival in 2021, the average ρ(PM2.5) of "2+26" cities was 85 µg·m-3, and the hourly peak ρ(PM2.5) was 125 µg·m-3. During this period, the hour number of heavy and severe pollution was the lowest in 2016 to 2021. Component observation results showed that the impact of fireworks and firecrackers during the Spring Festival and the Lantern Festival in 2021 was gradually reduced, and the effect of bans and restrictions for fireworks and firecrackers was significant. The regional pollution was dominated by conventional pollution accumulation and nitrate. The concentration of organic matter in some cities during the Spring Festival was relatively high, which may be related to local industrial emissions and the impact of blasting fireworks and firecrackers. The comparative analysis of meteorological factors and PM2.5 concentration showed that the factors such as wind speed and direction, ground pressure, and relative humidity all affected PM2.5 concentration and the duration of the regional pollution process. The influence of oscillation of the boundary layer transport sink on diffusion conditions in the North China Plain, the location and intensity of the small high pressure in North China and the intensity of its high-altitude moving airflow, and the uncertainty of fireworks displays, as well as the low accuracy of weather forecasts caused by frequent weather changes during the alternate period of winter and spring, could affect the accuracy of air quality forecast results in the northern Beijing-Tianjin-Hebei region. In summary, although the impact of fireworks and firecrackers has been reduced in recent years, in order to improve the air quality, it is recommended to further strengthen the control of fireworks and firecrackers, especially outside the Beijing Fifth Ring Road and Beijing's surrounding cities.


Subject(s)
Air Pollutants , Air Pollution , Air Pollutants/analysis , Air Pollution/analysis , China , Cities , Environmental Monitoring/methods , Holidays , Particulate Matter/analysis , Retrospective Studies , Seasons
20.
Curr Probl Cancer ; 46(3): 100850, 2022 06.
Article in English | MEDLINE | ID: mdl-35339820

ABSTRACT

Existing literature suggests inferior quality of oncologic surgery during holiday periods. This study aimed to investigate the impact of holiday periods on surgical treatment of gastric cancer in the Netherlands. This nationwide study included all gastric cancer patients undergoing potentially curative surgery registered in the Dutch Upper Gastrointestinal Cancer Audit (DUCA). For each patient it was established whether they underwent surgery during or outside the 11 Dutch holiday weeks, based on date and region of surgery. Separate, single-day holidays were not included. Baseline and treatment characteristics were compared using descriptive statistics. Time from diagnosis to treatment and short-term surgical outcomes were compared using multilevel multivariable logistic regression analyses. To prevent bias from recent advancements, analyses were repeated in a recent cohort of patients (2015-2018). Between 2011-2018, 3440 patients were included in the DUCA. Some 555 (16.1%) patients underwent surgery during 11 holiday weeks. There were no differences in patient, tumor and treatment characteristics and time to treatment between holidays and non-holidays. Tumor-positive resection margins (R1/R2 vs R0) occurred more frequent during holidays (aOR:1.47, 95%CI:1.07-2.04). Subgroup analyses in a recent cohort of patients also found higher tumor-positive resection margins (aOR:1.59, 95%CI:1.01-2.43) and higher failure-to-rescue rates (aOR:2.55, 95%CI:1.18-5.49) during holidays. Even though time to treatment and patient, tumor and treatment characteristics were comparable between holidays and non-holidays, tumor-positive resection margin and failure-to-rescue rates were higher during holidays. This suggests that steps must be taken to keep specialized and dedicated gastric cancer expertise up to standard during holiday periods.


Subject(s)
Esophageal Neoplasms , Stomach Neoplasms , Cohort Studies , Holidays , Humans , Margins of Excision , Stomach Neoplasms/epidemiology , Stomach Neoplasms/surgery
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