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1.
Buenos Aires; OPS; 2022-01.
in Spanish | PAHO-IRIS | ID: phr2-55559

ABSTRACT

Informe de situación generado por la representación de OPS/OMS en Argentina con información importante relacionada con COVID-19 a nivel regional y global, dirigida a tomadores de decisión, organizaciones sociales, funcionarios, académicos y otras instituciones del sector salud, a través de mensajes claros basados en fuentes confiables.


Subject(s)
Coronavirus , COVID-19 , Argentina , Research , Epidemics , Pandemics , COVID-19 Vaccines
2.
Zhonghua Jie He He Hu Xi Za Zhi ; 45(1): 88-94, 2022 Jan 12.
Article in Chinese | MEDLINE | ID: mdl-35000312

ABSTRACT

In the last decade, interventional pulmonology has developed rapidly, and gradually become a mature subspecialty in modern respiratory medicine, playing a more and more important role in the diagnosis and treatment of respiratory diseases. Especially in recent years, with the development of the related technology, various new technologies of interventional pulmonology came out and are gradually applied to chronic respiratory diseases which were mainly treated with drugs before, greatly expanding the application field of interventional pulmonology. Here, we reviewed the new progress and up-to-date research achievements of interventional pulmonology from 2020 to 2021.


Subject(s)
Pulmonary Medicine , Bronchoscopy , Research
3.
Brain Nerve ; 74(1): 36-39, 2022 Jan.
Article in Japanese | MEDLINE | ID: mdl-34992169

ABSTRACT

The COVID-19 pandemic, caused by a new type of coronavirus, has increased the difficulty of studying abroad for basic research. However, the associated system has changed in response to the coronavirus disaster. In addition, a framework has been built to enable research to be conducted even under a new lifestyle. Although there are many differences betwee studying abroad currently and before the pandemic, you should not give up on your dreams; I encourage you to open the door and challenge yourself.


Subject(s)
COVID-19 , Pandemics , Humans , Pandemics/prevention & control , Research , SARS-CoV-2
4.
Zool Res ; 43(1): 1-2, 2022 01 18.
Article in English | MEDLINE | ID: mdl-34821084
6.
Pediatr Infect Dis J ; 41(1): e1-e5, 2022 01 01.
Article in English | MEDLINE | ID: mdl-34784302

ABSTRACT

Children, although at lower risk of poor outcomes from COVID-19 relative to adults, still stand to benefit from therapeutic interventions. Understanding of COVID-19 clinical presentation and prognosis in children is essential to optimize therapeutic trials design. This perspective illustrates how to collectively accelerate pediatric COVID-19 therapeutic research and development, based on the experience of the Global Accelerator for Paediatric Formulations.


Subject(s)
COVID-19/drug therapy , Research , Seizures/drug therapy , Child , Dosage Forms , Drug Compounding , Drug Development , Humans , Needs Assessment , Pharmaceutical Preparations , SARS-CoV-2
8.
J Low Genit Tract Dis ; 26(1): 73-78, 2022 Jan 01.
Article in English | MEDLINE | ID: mdl-34928256

ABSTRACT

OBJECTIVE: This series of articles, titled The Vaginal Microbiome, written on behalf of the International Society for the Study of Vulvovaginal Disease, aims to summarize the current findings and understanding of the vaginal bacterial microbiota, mainly regarding areas relevant to clinicians specializing in vulvovaginal disorders. MATERIALS AND METHODS: A database search of PubMed was performed, using the search terms "vaginal microbiome" (VMB) with "research," "normal," "neonate," "puberty," "adolescent," "menopause," and "ethnicities," as well as "human microbiome project." Full article texts were reviewed. Reference lists were screened for additional articles. RESULTS: In the last 2 decades, many studies applying molecular techniques were performed, intending to characterize the vaginal microbiota. These studies advanced our understanding of how vaginal health is defined. The first article in this series focuses on the advancement of VMB research, technical definitions, the definition of "normal" VMB, and the dynamics of VMB throughout women's lives. CONCLUSIONS: Understanding how microorganisms inhabiting the vagina interact with each other and with the host is important for a more complete understanding of vaginal health. The clinical application of microbial community sequencing is in its beginning, and its interpretation regarding practical clinical aspects is yet to be determined.


Subject(s)
Microbiota , Adolescent , Bacteria , Female , Humans , Infant, Newborn , Menopause , Research , Vagina
10.
Esc. Anna Nery Rev. Enferm ; 26: e20210312, 2022. tab
Article in Portuguese | LILACS, BDENF - Nursing | ID: biblio-1346053

ABSTRACT

RESUMO Objetivo analisar as interfaces e distinções histórico-conceituais acerca dos estudos documentais, enquanto método de pesquisa, na área da Enfermagem e da saúde. Método ensaio teórico de cunho reflexivo, elaborado com base na literatura nacional e internacional sobre o tema. Resultados apresenta uma teorização acerca da evolução conceitual dos documentos e as contribuições advindas da Escola de Annales, com ênfase na expansão documental, também referida como revolução. Fundamenta conceitos, organização, coleta e análise dos dados documentais e as relações com a pesquisa histórica aplicada à Enfermagem e, por conseguinte, à saúde. Aborda a produção do conhecimento como parte do desenvolvimento da educação e da pesquisa em Enfermagem, no Brasil. Conclusões e implicações para a prática a apropriação das fontes documentais e dos métodos no desenvolvimento da pesquisa, do ensino e da assistência à saúde aguçam a curiosidade e ampliam a capacidade de análise, de crítica e de autonomia de grupos de interesse e estudiosos, esperando-se, com isso, a ampliação do conhecimento relacionado à profissão.


RESUMEN Objetivo analizar las interfaces y distinciones histórico-conceptuales acerca de los estudios documentales cómo método de investigación en el campo de la Enfermería y la salud. Método ensayo teórico con carácter reflexivo basado en la literatura nacional e internacional sobre el tema. Resultados presenta una teorización sobre la evolución conceptual de los documentos y los aportes de la Escuela de los Annales con énfasis en la expansión documental. Apoya conceptos, organización, recolección y análisis de datos documentales y sus relaciones con la investigación histórica en Enfermería y, por consiguiente, en salud. Aborda la producción de conocimiento como parte de la evolución de la educación y la investigación en Enfermería en Brasil. Conclusiones e implicaciones para la práctica la apropiación de fuentes y métodos documentales en el desarrollo de la investigación, la docencia y la salud agudiza la curiosidad y amplía la capacidad de análisis, crítica y autonomía de grupos de interés y académicos.


ABSTRACT Objective to analyze the historical-conceptual interfaces and distinctions regarding documentary studies as a research method in the field of Nursing and health. Method theoretical essay with a reflective nature based on national and international literature on the subject. Results the study presents a theorization about the conceptual evolution of documents and the contributions of Annales School, with emphasis on document expansion, also referred to as revolution. It supports concepts, organization, collection and analysis of documentary data and its relationships with historical research applied to Nursing and, therefore, to health. It addresses the production of knowledge as part of the evolution of education and research in Nursing in Brazil. Conclusions and implications for practice the appropriation of documentary sources and methods in the development of research, teaching and health care sharpens curiosity and expands the capacity for analysis, criticism and autonomy of interest groups and scholars, being expected, with this, the expansion of knowledge related to the profession.


Subject(s)
Humans , Research/history , Records , Surveys and Questionnaires , Nursing , Information/history , Research Personnel
11.
Ciudad Autónoma de Buenos Aires; Ministerio de Salud de la Nación; 13 Diciembre 2021. 43 p.
Monography in Spanish | BINACIS, ARGMSAL | ID: biblio-1348900

ABSTRACT

INTRODUCCIÓN: Una Agenda Nacional de Investigación en Salud Pública (ANISP) participativa y con priorización temática constituye un elemento estratégico para generar recomendaciones y políticas públicas basadas en evidencia, que impacten positivamente en la salud de las poblaciones y permitan lograr los objetivos sanitarios. En la actualización de la ANISP participaron la Dirección de Investigación en Salud (DIS) del Ministerio de Salud de la Nación (MSAL), a través de la Red Ministerial de Investigación en Salud (REMINSA), y actores de los niveles gubernamentales provinciales y nacionales pertenecientes a los sectores público, privado, de la salud, académico y de investigación. Se adaptó la herramienta original propuesta por la Organización Panamericana de la Salud, utilizada en el proceso en 2019. La actualización abarcó diferentes etapas. La selección de los temas contó con la legitimidad, reconocimiento y participación de los actores vinculados a la salud, a la gestión gubernamental y privada y a la investigación científica; se trabajó de manera federal y transversal, por consenso con las redes provinciales y un Comité Central Asesor en el MSAL. A partir de los lineamientos preliminares obtenidos, se elaboró una encuesta en línea semiestructurada, que fue distribuida a todos los actores federales y recibió 431 respuestas. El proceso resultó en 55 lineamientos priorizados, divididos en 6 áreas temáticas y 33 subtemas, seleccionados por votación según importancia, impacto y factibilidad.


Subject(s)
Argentina , Research , Public Health
12.
Cells ; 10(12)2021 12 17.
Article in English | MEDLINE | ID: mdl-34944076

ABSTRACT

Hydrogels are commonly used for the 3D culture of musculoskeletal cells. Sulfated hydrogels, which have seen a growing interest over the past years, provide a microenvironment that help maintain the phenotype of chondrocytes and chondrocyte-like cells and can be used for sustained delivery of growth factors and other drugs. Sulfated hydrogels are hence valuable tools to improve cartilage and intervertebral disc tissue engineering. To further advance the utilization of these hydrogels, we identify and summarize the current knowledge about different sulfated hydrogels, highlight their beneficial effects in cartilage and disc research, and review the biofabrication processes most suitable to secure best quality assurance through deposition fidelity, repeatability, and attainment of biocompatible morphologies.


Subject(s)
Cartilage/drug effects , Hydrogels/pharmacology , Intervertebral Disc/drug effects , Research , Sulfates/pharmacology , Animals , Humans , Hydrogels/chemistry , Sulfates/chemistry , Tissue Engineering
14.
Drug Discov Today Technol ; 40: 69-75, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34916026

ABSTRACT

In this paper, we review the growing development and applications of supercritical fluid chromatography-mass spectrometry (SFC-MS) for the analysis of small molecular analytes and biomarkers in drug discovery. As an alternative chromatographic technique, SFC instrumentation and methodology have dramatically advanced over the last decade. Mass spectrometry (MS) provides the powerful detection capability as it couples with SFC. A growing number of SFC-MS/MS applications were reported over the last decade and the application areas of SFC-MS/MS is rapidly expanding. The first part of this review is devoted to the different aspects of SFC-MS development and recent technological advancements. In the second part of this review, we highlight the recent application areas in pharmaceutical research and development.


Subject(s)
Chromatography, Supercritical Fluid , Pharmaceutical Preparations , Chromatography, Liquid , Research , Tandem Mass Spectrometry
15.
Health Res Policy Syst ; 19(1): 142, 2021 Dec 11.
Article in English | MEDLINE | ID: mdl-34895277

ABSTRACT

BACKGROUND: In recent years there have been calls to strengthen health sciences research capacity in African countries. This capacity can contribute to improvements in health, social welfare and poverty reduction through domestic application of research findings; it is increasingly seen as critical to pandemic preparedness and response. Developing research infrastructure and performance may reduce national economies' reliance on primary commodity and agricultural production, as countries strive to develop knowledge-based economies to help drive macroeconomic growth. Yet efforts to date to understand health sciences research capacity are limited to output metrics of journal citations and publications, failing to reflect the complexity of the health sciences research landscape in many settings. METHODS: We map and assess current capacity for health sciences research across all 54 countries of Africa by collecting a range of available data. This included structural indicators (research institutions and research funding), process indicators (clinical trial infrastructures, intellectual property rights and regulatory capacities) and output indicators (publications and citations). RESULTS: While there are some countries which perform well across the range of indicators used, for most countries the results are varied-suggesting high relative performance in some indicators, but lower in others. Missing data for key measures of capacity or performance is also a key concern. Taken as a whole, existing data suggest a nuanced view of the current health sciences research landscape on the African continent. CONCLUSION: Mapping existing data may enable governments and international organizations to identify where gaps in health sciences research capacity lie, particularly in comparison to other countries in the region. It also highlights gaps where more data are needed. These data can help to inform investment priorities and future system needs.


Subject(s)
Pandemics , Research , Africa , Humans
16.
Investig. psicol. (La Paz, En línea) ; 26: 119-129, dic. 2021.
Article in Spanish | LILACS | ID: biblio-1348945

ABSTRACT

El objetivo de la presente investigación es determinar los factores asociados a la procrastinación en una muestra de 210 estudiantes de educación básica y bachillerato de una institución educativa de Salcedo (Ecuador) con una media de M=13.81 años y una desviación estándar de DE=1.81 años. Para ello se aplicó la escala de Procrastinación Académica (EPA) y se analizaron los resultados de la misma con factores como el género, la procedencia (urbano/rural), el año académico, la situación económica y las actividades extracurriculares (estudiar y apoyar en empresas familiares o solo estudiar). Se encuentra que la situación económica y la ocupación tienen relación estadísticamente significativa (p< ,05) con la procrastinación académica. Siendo que los que tienen una situación económica mejor procrastinan menos al igual que los que apoyan en negocios familiares. Por otra parte, se encuentra que la procrastinación varía en base al año académico. Se concluye que la PA es sensible ante factores de carácter socioeconómico, académico y familiar.(AU)


This research aims to determine the factors associated with procrastination on a sample of 210 students of basic and baccalaureate education in Salcedo (Ecuador) with a mean of 13.81 of age and a standard deviation of 1.81 of age. The Academic Procrastination Scale (APS) was conducted based on gender, background (urban/rural), academic year, economic status, after school activities (such as studying and supporting family businesses or simply studying). The findings show that economic status and day-to-day activities are significantly associated (p< .05) with academic procrastination. Hence, those who procrastinate less are better off financially or support their family business. On the other hand, it was found that procrastination vary by school year. Results indicate that Academic Procrastination (AP) is particularly sensitive to socioeconomic, academic and family factors.(AU)


Procrastinação em uma amostra de 210 estudantes do ensino fundamental e médio de uma instituição de ensino de Salcedo (Equador) com média de M = 13,81 anos e desvio padrão de DP = 1,81 anos. Para isso, foi aplicada a escala de Procrastinação Acadêmica (EPA) e seus resultados foram analisados com fatores como sexo, procedência (urbana / rural), ano acadêmico, situação econômica e atividades extracurriculares (estudo e apoio em empresas familiares ou apenas estudar). Verifica-se que a situação econômica e a ocupação têm uma relação estatisticamente significante (p <, 05) com a procrastinação acadêmica. Sendo que aqueles que têm uma melhor situação econômica procrastinam menos como aqueles que apóiam nas empresas familiares. Por outro lado, verifica-se que a procrastinação varia de acordo com o ano acadêmico. Conclui-se que a PA é sensível a fatores socioeconômicos, acadêmicos e familiares.(AU)


Subject(s)
Socioeconomic Factors , Procrastination , Research , Students
17.
Isr J Health Policy Res ; 10(1): 66, 2021 12 15.
Article in English | MEDLINE | ID: mdl-34906251

ABSTRACT

For ten years the Israel Journal of Health Policy Research has provided a platform for exchange of knowledge and insights on health policy. It is a unique attempt by scholars and practitioners in one small country to share their knowledge with the world and, in turn to learn from experience elsewhere. Never has this role been as important as during the COVID pandemic, a message that is very clear when we look at failings elsewhere.


Subject(s)
COVID-19 , Health Policy , Humans , Israel , Research , SARS-CoV-2
18.
West Afr J Med ; Vol. 38(11): 1058-1064, 2021 11 30.
Article in English | MEDLINE | ID: mdl-34919362

ABSTRACT

BACKGROUND: Health behavior theories suggest that knowledge about the health risks of the behavior precedes behavior change. Tobacco control messages aim to promote knowledge of health risks associated with tobacco use and encourage smoking cessation behaviors such as quit attempts and intention to quit. This study assessed the relationship between exposure to Anti-Tobacco Messaging (ATM) and quit attempts among adolescents and young adults in Lagos, Nigeria. METHODS: This was an online cross-sectional survey of 947 participants aged between 15-35 years. The survey obtained sociodemographic information, smoking status, exposure to ATM, intention to quit and quit attempts in the past 12-months. Logistic regression analysis was used to identify the relationship between exposure to ATM and quit attempts; pvalues <0.05 were considered significant. Statistical analysis was done using STATA-15.0 software. RESULTS: The mean age of respondents was 23.4 years (SD:4.0). Less than one-third of the respondents were smokers (23.4%). The most common source of ATM were digital sources (online and social media - 29.6%). Based on the multivariable logistic regression model, younger age (p:0.03) and an intention to quit (p: <0.001) were significantly associated with a quit attempt. Exposure to ATM in the past 12 months was also significantly associated with higher odds of a quit attempt (OR:5.33; 95% CI: 1.26,22.60; p: 0.02). CONCLUSION: Our findings suggest an association between exposure to ATM and quit attempts among adolescent and young adult smokers in Lagos State, Nigeria. Policymakers should consider measures aimed at promoting tobacco control education and improving access to smoking cessation services.


Subject(s)
Research , Tobacco , Adolescent , Adult , Cross-Sectional Studies , Humans , Nigeria , Tobacco Use , Young Adult
19.
Psychiatr Hung ; 36(4): 518-535, 2021.
Article in Hungarian | MEDLINE | ID: mdl-34939570

ABSTRACT

There is no single easy way of suicide risk assessment. Although more and more theories try to describe sui - cide behavior, our scales struggle with severe psychometric limitations. While quantitative psychometric scales stand on a theoretically firm basis, their sensitivity is poor; (semi)structured, qualitative interviews are systematic and com - prehensive but costly and time-consuming. Interviews, compared to scales, also represent a new approach in suicide risk assessment. In this approach, among other things, expanding clinicians' knowledge about suicide, the narrative approach of a suicide crisis and suicide attempt, and a more specified formulation of the risk level and indicated intervention are central. Following the theoretical part of the paper, I will describe two assessment tools that represent the quantitative and qualitative approaches, respectively. I would like to argue that both short psychometric scales and systematic interviews have their salient role in different areas of clinical practice. Systematic interviews could play an important role in postgraduate education as with their help the approach to suicide risk evaluation as a process can be conveyed to professionals.


Subject(s)
Goals , Motivation , Humans , Psychometrics , Research , Risk Assessment , Suicide, Attempted
20.
Dev Psychol ; 57(12): 2007-2010, 2021 Dec.
Article in English | MEDLINE | ID: mdl-34928654

ABSTRACT

Despite its importance, replication has remained in the background of social development research. The aim of this special section was to elucidate and elevate the role of replication in peer relations research, examining its challenges and its utility for moving the field forward. To accomplish this aim, five sets of researchers undertook identifying an important finding from a widely cited article in the peer literature and tried to replicate its basic results using new data. As a group, the resulting five articles cover a broad range of topics, measures, and methods that are seen in peer research. Four of the five articles provide evidence of replication. This evidence was seen more for basic principles or processes observed in earlier studies than for exact or specific findings. In addition, the authors used varied approaches to replication, highlighting the need to embrace diverse methods when attempting to replicate complicated mechanisms of social development. It is argued that replication efforts should be aimed at identifying basic principles and processes of social development while clarifying the parameters that account for variability across studies in the specific findings. (PsycInfo Database Record (c) 2021 APA, all rights reserved).


Subject(s)
Peer Review , Research , Humans , Research/standards
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