1.
Acta Crystallogr E Crystallogr Commun
; 78(Pt 9): 880-884, 2022 Sep 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36072522
RESUMEN
In the title compound, C24H23FN4O4S·0.25H2O, the di-hydro-pyrimidine ring is distinctly non-planar, with the flap C atom deviating by 0.297â (2)â Å from the least-squares plane. In the crystal, zigzag chains are formed by N-Hâ¯N hydrogen bonds parallel to [010] and are connected into layers parallel to (100) by O-Hâ¯O, O-Hâ¯F, C-Hâ¯O, C-Hâ¯F and C-Hâ¯N hydrogen bonds. Additional C-Hâ¯O hydrogen bonds connect the layers into a three-dimensional network. A Hirshfeld surface analysis indicates that the most significant contributions to the crystal packing are from Hâ¯H (42.6%), Oâ¯H/Hâ¯O (16.8%) and Câ¯H/Hâ¯C (15.5%) contacts.