RESUMEN
The problem of ultrafine particles (UFPs; PM0.1) has been prevalent since the past decades. In addition to become easily inhaled by human respiratory system due to their ultrafine diameter (<100 nm), ambient UFPs possess various physicochemical properties which make it more toxic. These properties vary based on the emission source profile. The current development of UFPs studies is hindered by the problem of expensive instruments and the inexistence of standardized measurement method. This review provides detailed insights on ambient UFPs sources, physicochemical properties, measurements, and estimation models development. Implications on health impacts due to short-term and long-term exposure of ambient UFPs are also presented alongside the development progress of potentially low-cost UFPs sensors which can be used for future UFPs studies references. Current challenge and future outlook of ambient UFPs research are also discussed in this review. Based on the review results, ambient UFPs may originate from primary and secondary sources which include anthropogenic and natural activities. In addition to that, it is confirmed from various chemical content analysis that UFPs carry heavy metals, PAHs, BCs which are toxic in its nature. Measurement of ambient UFPs may be performed through stationary and mobile methods for environmental profiling and exposure assessment purposes. UFPs PNC estimation model (LUR) developed from measurement data could be deployed to support future epidemiological study of ambient UFPs. Low-cost sensors such as bipolar ion and ionization sensor from common smoke detector device may be further developed as affordable instrument to monitor ambient UFPs. Recent studies indicate that short-term exposure of UFPs can be associated with HRV change and increased cardiopulmonary effects. On the other hand, long-term UFPs exposure have positive association with COPD, CVD, CHF, pre-term birth, asthma, and also acute myocardial infarction cases.
