RESUMEN
We have determined the nucleotide sequence of DNA extracted from pustules, saliva, and blood of camels presenting with contagious ecthyma, in Bahrain and also from a sample (SACamel) of infected tissue from a camel that had presented with contagious ecthyma in 1998 in Saudi Arabia (1). Sequence homologies and phylogenetic analysis showed that this extracted DNA was more closely related to Pseudocowpox virus (PCPV) than Orf virus (ORFV), which infects sheep, goats, and other animal species. The phylogeny also demonstrated that PCPV in Arabian camels was phylogenetically distinct from, and circulates independently of, ruminant-associated PCPV from Europe.
Asunto(s)
Camelus/virología , Ectima Contagioso/epidemiología , Filogenia , Infecciones por Poxviridae/veterinaria , Virus de la Seudoviruela de las Vacas/clasificación , Animales , Bahrein/epidemiología , Secuencia de Bases , ADN Viral/química , Brotes de Enfermedades/veterinaria , Ectima Contagioso/virología , Femenino , Masculino , Infecciones por Poxviridae/epidemiología , Infecciones por Poxviridae/virología , Virus de la Seudoviruela de las Vacas/aislamiento & purificación , Arabia Saudita/epidemiologíaRESUMEN
Rabbit haemorrhagic disease virus (RHDV) emerged in 1984 in China and subsequently a single strain apparently dispersed worldwide killing millions of rabbits. Two isolates that caused outbreaks in Saudi Arabia and Bahrain have been sequenced and analysed phylogenetically. The Saudi Arabian lineage is directly descended from the Chinese strain, but the Bahrain isolate occupies a distinct and more divergent lineage than the Chinese virus implying that epidemic RHDV strains have emerged at least twice during the past 20 years and are co-circulating in both domestic and wild rabbits.