RESUMEN
Molluscum contagiosum is a disease caused by a poxvirus. It is more prevalent in children up to 5 years of age. There is a second peak of incidence in young adults. In order to examine its ultrastructure, three lesions were curetted without disruption, cut transversely with a scalpel, and routinely processed for scanning electron microscopy (SEM). The oval structure of molluscum contagiosum could be easily identified. In its core, there was a central umbilication and just below this depression, there was a keratinized tunnel. Under higher magnification, a proliferation similar to the epidermis was seen. Moreover, there were areas of cells disposed like a mosaic. Under higher magnification, rounded structures measuring 0.4 micron could be observed at the end of the keratinized tunnel and on the surface of the lesion.
Asunto(s)
Molusco Contagioso/patología , Humanos , Microscopía Electrónica de RastreoRESUMEN
Molluscum contagiosum is a disease caused by a poxvirus. It is more prevalent in children up to 5 years of age. There is a second peak of incidence in young adults. In order to examine its ultrastructure, three lesions were curetted without disruption, cut transversely with a scalpel, and routinely processed for scanning electron microscopy (SEM). The oval structure of molluscum contagiosum could be easily identified. In its core, there was a central umbilication and just below this depression, there was a keratinized tunnel. Under higher magnification, a proliferation similar to the epidermis was seen. Moreover, there were areas of cells disposed like a mosaic. Under higher magnification, rounded structures measuring 0.4 micron could be observed at the end of the keratinized tunnel and on the surface of the lesion.
Molusco contagioso é uma dermatovirose causada por um poxvírus, sendo mais prevalente em crianças com até 5 anos de idade. Um segundo pico de incidência é encontrado em adultos jovens. Com o objetivo de demonstrar sua ultraestrutura três lesões foram curetadas sem rompê-las, cortadas transversalmente e processadas de rotina para microscopia eletrônica de varredura. A estrutura oval do Molusco contagioso pôde ser facilmente observada, no seu centro há uma umbilicação central e logo abaixo observa-se um túnel queratinizado. Com aumentos progressivos observam-se proliferações semelhantes à epiderme e áreas de células dispostas em mosaico. Com grandes aumentos estruturas arredondadas medindo 0,4 micron são vistas no final do túnel queratinizado e na superfície da lesão.