Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 21
Filtrar
1.
Skeletal Radiol ; 2024 Mar 05.
Artículo en Inglés | MEDLINE | ID: mdl-38441615

RESUMEN

Soccer is a global widespread sport with a high injury rate, mostly to the lower limbs. Even though upper limb injuries are much less common among soccer players, their prevalence has increased in recent years. This is due to several reasons/factors, including new and more aggressive tactics, a rise in the number of younger players with different levels of skeletal maturation, and due to the growth of women's participation in sports, which is in line with the fast progression in the degree of professionalism in women's soccer. This review paper aims to (a) describe the most common injuries in the shoulder, arm, and elbow in soccer players and (b) to show the role of different imaging modalities in diagnosing upper extremity injuries that can occur in this sport. Familiarity with these injuries and their mechanisms will lead to a quicker diagnosis and correct reporting of imaging of soccer players.

2.
Eur Radiol ; 33(9): 6322-6338, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37191922

RESUMEN

OBJECTIVES: The purpose of this agreement was to establish evidence-based consensus statements on imaging of distal radioulnar joint (DRUJ) instability and triangular fibrocartilage complex (TFCC) injuries by an expert group using the Delphi technique. METHODS: Nineteen hand surgeons developed a preliminary list of questions on DRUJ instability and TFCC injuries. Radiologists created statements based on the literature and the authors' clinical experience. Questions and statements were revised during three iterative Delphi rounds. Delphi panelists consisted of twenty-seven musculoskeletal radiologists. The panelists scored their degree of agreement to each statement on an 11-item numeric scale. Scores of "0," "5," and "10" reflected complete disagreement, indeterminate agreement, and complete agreement, respectively. Group consensus was defined as a score of "8" or higher for 80% or more of the panelists. RESULTS: Three of fourteen statements achieved group consensus in the first Delphi round and ten statements achieved group consensus in the second Delphi round. The third and final Delphi round was limited to the one question that did not achieve group consensus in the previous rounds. CONCLUSIONS: Delphi-based agreements suggest that CT with static axial slices in neutral rotation, pronation, and supination is the most useful and accurate imaging technique for the work-up of DRUJ instability. MRI is the most valuable technique in the diagnosis of TFCC lesions. The main indication for MR arthrography and CT arthrography are Palmer 1B foveal lesions of the TFCC. CLINICAL RELEVANCE STATEMENT: MRI is the method of choice for assessing TFCC lesions, with higher accuracy for central than peripheral abnormalities. The main indication for MR arthrography is the evaluation of TFCC foveal insertion lesions and peripheral non-Palmer injuries. KEY POINTS: • Conventional radiography should be the initial imaging technique in the assessment of DRUJ instability. CT with static axial slices in neutral rotation, pronation, and supination is the most accurate method for evaluating DRUJ instability. • MRI is the most useful technique in diagnosing soft-tissue injuries causing DRUJ instability, especially TFCC lesions. • The main indications for MR arthrography and CT arthrography are foveal lesions of the TFCC.


Asunto(s)
Inestabilidad de la Articulación , Fibrocartílago Triangular , Traumatismos de la Muñeca , Humanos , Fibrocartílago Triangular/diagnóstico por imagen , Traumatismos de la Muñeca/diagnóstico por imagen , Imagen por Resonancia Magnética , Inestabilidad de la Articulación/diagnóstico por imagen , Inestabilidad de la Articulación/cirugía , Artrografía , Articulación de la Muñeca/diagnóstico por imagen , Artroscopía/métodos
3.
Semin Musculoskelet Radiol ; 27(3): 337-350, 2023 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-37230133

RESUMEN

Lesser (or central) metatarsalgia is defined as pain in the forefoot under or around the lesser metatarsals and their respective metatarsophalangeal joints. Two common causes of central metatarsalgia are Morton's neuroma (MN) and plantar plate (PP) injury. Because both clinical and imaging features overlap, establishing the correct differential diagnosis may be challenging. Imaging has a pivotal role in the detection and characterization of metatarsalgia. Different radiologic modalities are available to assess the common causes of forefoot pain, so the strengths and weakness of these imaging tools should be kept in mind. It is crucial to be aware of the pitfalls that can be encountered in daily clinical practice when dealing with these disorders. This review describes two main causes of lesser metatarsalgia, MN and PP injury, and their differential diagnoses.


Asunto(s)
Metatarsalgia , Humanos , Diagnóstico Diferencial , Metatarsalgia/diagnóstico por imagen , Metatarsalgia/etiología , Pie
4.
J Hand Surg Glob Online ; 4(5): 283-287, 2022 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-36157301

RESUMEN

We report the case of a 34-year-old woman with hypothenar pain due to a solitary neurofibroma (NF) of the ulnar nerve, with an extrafascicular location, outside Guyon canal, with no clinical evidence of associated neurologic impairment, who was successfully treated with surgical resection. The identification of this isolated tumor led to the diagnosis of a new genetic variant of neurofibromatosis type 1 after genome sequencing. At the 1-year follow-up, the patient remains asymptomatic without recurrence or other peripheral nerve sheath tumors. A solitary NF of a deep-seated nerve is extremely rare, especially in the context of neurofibromatosis type 1. To our knowledge, there are no reports of a NF of the ulnar nerve with an extraneural location. In the presence of a solitary NF related to a deep-seated peripheral nerve, neurofibromatosis type 1 should always be excluded.

5.
Eur Radiol ; 31(12): 9446-9458, 2021 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-34100996

RESUMEN

OBJECTIVES: The purpose of this agreement was to establish evidence-based consensus statements on imaging of scapholunate joint (SLJ) instability by an expert group using the Delphi technique. METHODS: Nineteen hand surgeons developed a preliminary list of questions on SLJ instability. Radiologists created statements based on the literature and the authors' clinical experience. Questions and statements were revised during three iterative Delphi rounds. Delphi panellists consisted of twenty-seven musculoskeletal radiologists. The panellists scored their degree of agreement to each statement on an eleven-item numeric scale. Scores of '0', '5' and '10' reflected complete disagreement, indeterminate agreement and complete agreement, respectively. Group consensus was defined as a score of '8' or higher for 80% or more of the panellists. RESULTS: Ten of fifteen statements achieved group consensus in the second Delphi round. The remaining five statements achieved group consensus in the third Delphi round. It was agreed that dorsopalmar and lateral radiographs should be acquired as routine imaging work-up in patients with suspected SLJ instability. Radiographic stress views and dynamic fluoroscopy allow accurate diagnosis of dynamic SLJ instability. MR arthrography and CT arthrography are accurate for detecting scapholunate interosseous ligament tears and articular cartilage defects. Ultrasonography and MRI can delineate most extrinsic carpal ligaments, although validated scientific evidence on accurate differentiation between partially or completely torn or incompetent ligaments is not available. CONCLUSIONS: Delphi-based agreements suggest that standardized radiographs, radiographic stress views, dynamic fluoroscopy, MR arthrography and CT arthrography are the most useful and accurate imaging techniques for the work-up of SLJ instability. KEY POINTS: • Dorsopalmar and lateral wrist radiographs remain the basic imaging modality for routine imaging work-up in patients with suspected scapholunate joint instability. • Radiographic stress views and dynamic fluoroscopy of the wrist allow accurate diagnosis of dynamic scapholunate joint instability. • Wrist MR arthrography and CT arthrography are accurate for determination of scapholunate interosseous ligament tears and cartilage defects.


Asunto(s)
Inestabilidad de la Articulación , Traumatismos de la Muñeca , Artrografía , Consenso , Humanos , Inestabilidad de la Articulación/diagnóstico por imagen , Ligamentos Articulares/diagnóstico por imagen , Traumatismos de la Muñeca/diagnóstico por imagen , Articulación de la Muñeca
6.
Eur Radiol ; 31(7): 4634-4651, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33411052

RESUMEN

OBJECTIVES: Imaging assessment for the clinical management of femoroacetabular impingement (FAI) is controversial because of a paucity of evidence-based guidance and notable variability among practitioners. Hence, expert consensus is needed because standardised imaging assessment is critical for clinical practice and research. We aimed to establish expert-based statements on FAI imaging by using formal methods of consensus building. METHODS: The Delphi method was used to formally derive consensus among 30 panel members from 13 countries. Forty-four questions were agreed upon, and relevant seminal literature was circulated and classified in major topics to produce answering statements. The level of evidence was noted for all statements, and panel members were asked to score their level of agreement (0-10). This is the second part of a three-part consensus series and focuses on 'General issues' and 'Parameters and reporting'. RESULTS: Forty-seven statements were generated and group consensus was reached for 45. Twenty-five statements pertaining to 'General issues' (9 addressing diagnosis, differential diagnosis, and postoperative imaging) and 'Parameters and reporting' (16 addressing femoral/acetabular parameters) were produced. CONCLUSIONS: The available evidence was reviewed critically, recommended criteria for diagnostic imaging highlighted, and the roles/values of different imaging parameters assessed. Radiographic evaluation (AP pelvis and a Dunn 45° view) is the cornerstone of hip-imaging assessment and the minimum imaging study that should be performed when evaluating adult patients for FAI. In most cases, cross-sectional imaging is warranted because MRI is the 'gold standard' imaging modality for the comprehensive evaluation, differential diagnosis assessment, and FAI surgical planning. KEY POINTS: • Diagnostic imaging for FAI is not standardised due to scarce evidence-based guidance on which imaging modalities and diagnostic criteria/parameters should be used. • Radiographic evaluation is the cornerstone of hip assessment and the minimum study that should be performed when assessing suspected FAI. Cross-sectional imaging is justified in most cases because MRI is the 'gold standard' modality for comprehensive FAI evaluation. • For acetabular morphology, coverage (Wiberg's angle and acetabular index) and version (crossover, posterior wall, and ischial spine signs) should be assessed routinely. On the femoral side, the head-neck junction morphology (α° and offset), neck morphology (NSA), and torsion should be assessed.


Asunto(s)
Pinzamiento Femoroacetabular , Acetábulo , Adulto , Pinzamiento Femoroacetabular/diagnóstico por imagen , Fémur , Articulación de la Cadera/diagnóstico por imagen , Humanos , Imagen por Resonancia Magnética
7.
Eur Radiol ; 31(7): 4652-4668, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33411053

RESUMEN

OBJECTIVES: Imaging diagnosis of femoroacetabular impingement (FAI) remains controversial due to a lack of high-level evidence, leading to significant variability in patient management. Optimizing protocols and technical details is essential in FAI imaging, although challenging in clinical practice. The purpose of this agreement is to establish expert-based statements on FAI imaging, using formal consensus techniques driven by relevant literature review. Recommendations on the selection and use of imaging techniques for FAI assessment, as well as guidance on relevant radiographic and MRI classifications, are provided. METHODS: The Delphi method was used to assess agreement and derive consensus among 30 panel members (musculoskeletal radiologists and orthopedic surgeons). Forty-four questions were agreed on and classified into five major topics and recent relevant literature was circulated, in order to produce answering statements. The level of evidence was assessed for all statements and panel members scored their level of agreement with each statement during 4 Delphi rounds. Either "group consensus," "group agreement," or "no agreement" was achieved. RESULTS: Forty-seven statements were generated and group consensus was reached for 45. Twenty-two statements pertaining to "Imaging techniques" were generated. Eight statements on "Radiographic assessment" and 12 statements on "MRI evaluation" gained consensus. No agreement was reached for the 2 "Ultrasound" related statements. CONCLUSION: The first international consensus on FAI imaging was developed. Researchers and clinicians working with FAI and hip-related pain may use these recommendations to guide, develop, and implement comprehensive, evidence-based imaging protocols and classifications. KEY POINTS: • Radiographic evaluation is recommended for the initial assessment of FAI, while MRI with a dedicated protocol is the gold standard imaging technique for the comprehensive evaluation of this condition. • The MRI protocol for FAI evaluation should include unilateral small FOV with radial imaging, femoral torsion assessment, and a fluid sensitive sequence covering the whole pelvis. • The definite role of other imaging methods in FAI, such as ultrasound or CT, is still not well defined.


Asunto(s)
Pinzamiento Femoroacetabular , Consenso , Pinzamiento Femoroacetabular/diagnóstico por imagen , Cadera , Articulación de la Cadera/diagnóstico por imagen , Humanos , Imagen por Resonancia Magnética
8.
Orthop Traumatol Surg Res ; 107(1): 102747, 2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33333282

RESUMEN

BACKGROUND: The etiology and relevance of long head of biceps tendon (LHBT) pathology is debated. As it can have important therapeutic consequences and physical examination can be misleading, various morphologic parameters have been described to try to predict it. HYPOTHESIS: We hypothesized that bicipital groove cross-sectional area (CSA), as assessed by ultrasonography, could be related to intra-articular tendon pathology. MATERIAL AND METHODS: Fifty-eight consecutive consenting patients who underwent arthroscopic shoulder surgery at our hospital were selected. Diagnosis consisted mainly of rotator cuff tears, but also of anterior instability and subacromial impingement. Before surgery, ultrasonography was performed to measure width, depth and cross-sectional area of the bicipital groove. LHBT pathology was assessed during arthroscopy and classified as tendinopathy, partial disruption or complete tear and correlated to the ultrasonography measurements. RESULTS: Bicipital groove width was of 6.7±1.2mm in patients with a normal LHBT and 7.3±1.9mm with patients with an abnormal LHBT (p=0.234). Bicipital groove depth was of 3.5±0.5mm in patients with a normal LHBT and 3.7±1.1mm with patients with an abnormal LHBT (p=0.251). Bicipital groove CSA was of 16.6±4.5 mm2 in patients with a normal LHBT and 19.1±7.1 mm2 with patients with an abnormal LHBT (p=0.108). CONCLUSION: Our results do not support any correlation between LHBT pathology and the bicipital groove CSA, even though this measurement, as its width and depth, are somewhat higher in patients with a LHBT injury. LEVEL OF EVIDENCE: I; diagnostic study.


Asunto(s)
Lesiones del Manguito de los Rotadores , Articulación del Hombro , Artroscopía , Humanos , Lesiones del Manguito de los Rotadores/diagnóstico por imagen , Lesiones del Manguito de los Rotadores/cirugía , Hombro , Articulación del Hombro/diagnóstico por imagen , Articulación del Hombro/cirugía , Tendones/diagnóstico por imagen , Ultrasonografía
10.
Acta Reumatol Port ; 45(1): 20-25, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32572014

RESUMEN

Gout is the most common crystal arthropathy, accounting for up to 5% of all arthritis. The hallmark of the disease is hyperuricemia with the subsequent deposition of monosodium urate (MSU) crystals in the intra- and extra-articular soft tissues and bones, leading to inflammation of these tissues. Recurrent intermittent flares can result in chronic gouty arthritis leading to cartilage and bone destruction. The most sensitive and specific imaging methods for diagnosing acute gout are ultrasound and dual energy computed tomography (DECT). In the chronic or tophaceous gout, imaging may depict tophi and their local destructive effect on surrounding tissues with characteristic findings on radiographs. In this pictorial review the imaging features of acute and chronic gout on radiographs, ultrasound, and DECT are presented, as well as imaging pitfalls that one needs to be aware.


Asunto(s)
Gota/diagnóstico por imagen , Enfermedad Aguda , Artritis Gotosa/diagnóstico por imagen , Artritis Gotosa/etiología , Enfermedad Crónica , Gota/sangre , Gota/complicaciones , Humanos , Hiperuricemia/etiología , Sensibilidad y Especificidad , Tomografía Computarizada por Rayos X/métodos , Ultrasonografía , Ácido Úrico
11.
Eur Radiol ; 30(10): 5281-5297, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-32405754

RESUMEN

OBJECTIVES: Imaging assessment for the clinical management of femoroacetabular impingement (FAI) syndrome remains controversial because of a paucity of evidence-based guidance and notable variability in clinical practice, ultimately requiring expert consensus. The purpose of this agreement is to establish expert-based statements on FAI imaging, using formal techniques of consensus building. METHODS: A validated Delphi method and peer-reviewed literature were used to formally derive consensus among 30 panel members (21 musculoskeletal radiologists and 9 orthopaedic surgeons) from 13 countries. Forty-four questions were agreed on, and recent relevant seminal literature was circulated and classified in five major topics ('General issues', 'Parameters and reporting', 'Radiographic assessment', 'MRI' and 'Ultrasound') in order to produce answering statements. The level of evidence was noted for all statements, and panel members were asked to score their level of agreement with each statement (0 to 10) during iterative rounds. Either 'consensus', 'agreement' or 'no agreement' was achieved. RESULTS: Forty-seven statements were generated, and group consensus was reached for 45 (95.7%). Seventeen of these statements were selected as most important for dissemination in advance. There was no agreement for the two statements pertaining to 'Ultrasound'. CONCLUSION: Radiographic evaluation is the cornerstone of hip evaluation. An anteroposterior pelvis radiograph and a Dunn 45° view are recommended for the initial assessment of FAI although MRI with a dedicated protocol is the gold standard imaging technique in this setting. The resulting consensus can serve as a tool to reduce variability in clinical practices and guide further research for the clinical management of FAI. KEY POINTS: • FAI imaging literature is extensive although often of low level of evidence. • Radiographic evaluation with a reproducible technique is the cornerstone of hip imaging assessment. • MRI with a dedicated protocol is the gold standard imaging technique for FAI assessment.


Asunto(s)
Consenso , Pinzamiento Femoroacetabular/diagnóstico , Imagen por Resonancia Magnética/métodos , Humanos
12.
Semin Musculoskelet Radiol ; 23(3): e37-e57, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31163509

RESUMEN

Although it is possible for any osseous tumor or tumorlike lesion to occur in and around the hip and pelvis, there are preferential lesions. Most tumors share many imaging features with those arising elsewhere in the skeletal system, but some may show specific morphological and imaging features. Furthermore, specific criteria and rules of thumb are related to this anatomical area that radiologists should know, which together with the imaging findings and clinical context will lead to a more confident diagnosis.In this article we review the basic anatomical and imaging principles in the hip and pelvis and their diagnostic criteria, describe the most common regional benign and malignant bone tumors and pseudotumors, and highlight their main imaging features and common differential diagnosis while keep this article as relatively simple and straightforward as possible. Soft tissue tumors are beyond the scope of this article.


Asunto(s)
Neoplasias Óseas/diagnóstico por imagen , Imagen por Resonancia Magnética/métodos , Huesos Pélvicos/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Humanos
13.
Semin Musculoskelet Radiol ; 23(1): 3-18, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30699449

RESUMEN

Chondroid tumors are a heterogeneous group of neoplasms that all share the production of chondroid matrix. This ranges from a fetal type to mature hyaline cartilage and mirrors its imaging characteristics.The benign chondroid tumors represent some of the most encountered incidental bone lesions, with osteochondroma the most frequent benign bone tumor. Enchondroma is mostly asymptomatic, and yet it is probably the second most common primary bone tumor. Similarly, its malignant counterpart, chondrosarcoma, is the second most common malignant primary bone tumor.The 2013 World Health Organization (WHO) updated this group of tumors, and grade 1 chondrosarcoma was renamed "atypical cartilage tumor" and classified as an intermediate type of tumor, not a malignancy, which better describes its clinical behavior.In this article we summarize changes made in the updated 2013 WHO classification and highlight the diagnostic features differentiating an enchondroma from a low-grade chondrosarcoma. We also describe practical imaging aspects of the remaining chondroid tumors.


Asunto(s)
Neoplasias Óseas/diagnóstico por imagen , Condroma/diagnóstico por imagen , Condrosarcoma/diagnóstico por imagen , Hallazgos Incidentales , Biopsia , Neoplasias Óseas/patología , Condroma/patología , Condrosarcoma/patología , Diagnóstico Diferencial , Humanos , Clasificación del Tumor
14.
Skeletal Radiol ; 48(1): 167-174, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29934738

RESUMEN

Post-traumatic cyst-like lesions are an infrequent complication of fractures in children. To our knowledge, no more than 30 cases have been reported in the English-language literature. They most commonly affect the distal radius following a greenstick or torus fracture. These cortical defects are often asymptomatic, non-expansile, and typically resolve spontaneously in 1-3 years. They appear proximal to the compression site and are usually identified 2-4 months after a minor fracture. These lesions have a distinct appearance on magnetic resonance imaging (MRI), with intralesional fatty marrow, which may help to differentiate it from other bone lesions. We review the literature and present 3 more cases studied with plain radiographs, computed tomography (CT), and MRI. Post-traumatic cyst-like lesions require no treatment, and therefore recognition of its typical features is crucial to prevent unnecessary invasive procedures.


Asunto(s)
Quistes Óseos/diagnóstico por imagen , Fracturas del Radio/diagnóstico por imagen , Accidentes por Caídas , Niño , Humanos , Imagen por Resonancia Magnética , Masculino , Fracturas del Radio/terapia , Tomografía Computarizada por Rayos X
15.
Semin Musculoskelet Radiol ; 19(5): 475-82, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26696086

RESUMEN

Soft tissue sarcomas are rare, but early, accurate diagnosis with subsequent appropriate treatment is crucial for the clinical outcome. The ESSR guidelines are intended to help radiologists in their decision-making and support discussion among clinicians who deal with patients with suspected or proven soft tissue tumors. Potentially malignant lesions recognized by ultrasound should be referred for magnetic resonance imaging (MRI), which also serves as a preoperative local staging modality, with specific technical requirements and mandatory radiological report elements. Radiography may add information about matrix calcification and osseous involvement. Indeterminate lesions, or lesions in which therapy is dependent on histology results, should be biopsied. For biopsy, we strongly recommend referral to a specialist sarcoma center, where an interdisciplinary tumor group, with a specialized pathologist, radiologist, and the surgeon are involved. In sarcoma, a CT scan of the chest is mandatory. Additional staging modalities are entity-specific. There are no evidence-based recommendations for routine follow-up in surgically treated sarcomas. However, we would recommend regular follow-up with intervals dependent on tumor grade, for 10 years after the initial diagnosis.


Asunto(s)
Imagen por Resonancia Magnética , Guías de Práctica Clínica como Asunto , Neoplasias de los Tejidos Blandos/diagnóstico por imagen , Neoplasias de los Tejidos Blandos/patología , Adulto , Europa (Continente) , Humanos , Sociedades Médicas , Ultrasonografía
17.
Radiology ; 269(3): 816-23, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23925271

RESUMEN

PURPOSE: To determine the rate at which computed tomographically guided pelvic percutaneous bone biopsy in men with metastatic castration-resistant prostate cancer (mCRPC) yields adequate tissue for genomic profiling and to identify issues likely to affect diagnostic yields. MATERIALS AND METHODS: This study was institutional review board approved, and written informed consent was obtained. In a phase II trial assessing response to everolimus, 31 men with mCRPC underwent 54 biopsy procedures (eight men before and 23 men both before and during treatment). Variables assessed were lesion location (iliac wing adjacent to sacroiliac joint, iliac wing anterior and/or superior to sacroiliac joint, sacrum, and remainder of pelvis), mean lesion attenuation, subjective lesion attenuation (purely sclerotic vs mixed), central versus peripheral lesion sampling, lesion size, core number, and use of zoledronic acid for more than 1 year. RESULTS: Of 54 biopsy procedures, 21 (39%) yielded adequate tissue for RNA isolation and genomic profiling. Three of four sacral biopsies were adequate. Biopsies of the ilium adjacent to the sacroiliac joints were more likely adequate than those from elsewhere in the ilium (48% vs 28%, respectively). All five biopsies performed in other pelvic locations yielded inadequate tissue for RNA isolation. Mean attenuation of lesions with inadequate tissue was 172 HU greater than those with adequate tissue (621.1 HU ± 166 vs 449 HU ± 221, respectively; P = .002). Use of zoledronic acid, peripheral sampling, core number, and lesion size affected yields, but the differences were not statistically significant. Histologic examination with hematoxylin-eosin staining showed that results of 36 (67%) biopsies were positive for cancer; only mean attenuation differences were significant (707 HU ± 144 vs 473 HU ± 191, negative vs positive, respectively; P < .001). CONCLUSION: In men with mCRPC, percutaneous sampling of osseous metastases for genomic profiling is possible, but use of zoledronic acid for more than 1 year may reduce the yield of adequate tissue for RNA isolation. Sampling large low-attenuating lesions at their periphery maximizes yield.


Asunto(s)
Biopsia , Médula Ósea/patología , Perfilación de la Expresión Génica , Neoplasias de la Próstata/genética , Neoplasias de la Próstata/patología , ARN/aislamiento & purificación , Tomografía Computarizada por Rayos X , Ultrasonografía Intervencional , Conservadores de la Densidad Ósea/uso terapéutico , Difosfonatos/uso terapéutico , Everolimus , Humanos , Imidazoles/uso terapéutico , Inmunosupresores/uso terapéutico , Masculino , Neoplasias de la Próstata/diagnóstico por imagen , Neoplasias de la Próstata/tratamiento farmacológico , Sirolimus/administración & dosificación , Sirolimus/análogos & derivados , Ácido Zoledrónico
19.
Rev Port Cir Cardiotorac Vasc ; 19(4): 217-20, 2012.
Artículo en Portugués | MEDLINE | ID: mdl-24490199

RESUMEN

Aortic vascular anomalies are complex anatomic entities requiring often complex and problematic surgical approaches. The authors report the clinical case of a Kommerell's diverticulum and right-sided aortic arch. Right-sided aortic arch is an uncommon congenital defect of the aorta and it is rare in the setting of an otherwise normal heart. A right-sided aortic arch was described more than two centuries ago. Several classifications of these anomalies have been proposed on the basis of the arrangement of the arch vessels, relationships with the esophagus, or the presence of congenital heart anomalies. In the adult population, a right-sided aortic arch is often asymptomatic, unless aneurismal disease develops. This usually occurs at the level of the take-off of an aberrant left subclavian artery and is known as a Kommerell's diverticulum. In spite of its rarity, this condition is clinically relevant due to the mortality associated with rupture, morbidity caused by compression of mediastinal structures, and complexity of surgery.


Asunto(s)
Aneurisma/patología , Aorta Torácica/anomalías , Enfermedades de la Aorta/patología , Anomalías Cardiovasculares/patología , Trastornos de Deglución/patología , Divertículo/patología , Arteria Subclavia/anomalías , Enfermedades de la Aorta/congénito , Enfermedades de la Aorta/diagnóstico , Divertículo/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Arteria Subclavia/patología
20.
Acta Med Port ; 24(2): 349-54, 2011.
Artículo en Portugués | MEDLINE | ID: mdl-22011609

RESUMEN

The spine is the most common site of osseous involvement by tuberculosis. Diagnosis of tuberculous spondylodiskitis, also known as Pott's disease, is often difficult due to its insidious onset and nonspecific clinical presentation. Along with a high level of suspicion, familiarity with its imaging characteristics is the basis for establishing the correct diagnosis, allowing early and focused treatment.


Asunto(s)
Discitis/diagnóstico , Discitis/microbiología , Imagen por Resonancia Magnética , Tomografía Computarizada por Rayos X , Tuberculosis de la Columna Vertebral/diagnóstico , Diagnóstico Diferencial , Humanos
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...