Eventos adversos pós-vacinais em pacientes imunizados contra a COVID-19 em um município do sul de Santa Catarina no ano de 2021 / Post-vaccine adverse events in patients immunized against COVID-19 in a munici-pality in the south of Santa Catarina state in 2021

A disponibilização em massa de vacinas contra o vírus SARS-CoV-2 é resultado de esforços científicos mundiais. Entretanto, a insegurança e a hesitação popular per-meiam os movimentos antivacinais. Objetivo: Analisar o perfil dos Eventos Adver-sos Pós-Vacinais (EAPV) na cidade de Tubarão-SC no ano de 2021. Metodologia: Estudo epidemiológico transversal com dados de todas as fichas de notificação padrão de EAPV no município de Tubarão em 2021. As variáveis analisadas foram o perfil epidemiológico do paciente, imunobiológico administrado, o tipo de evento e a evolução do caso. Calculou-se a taxa de incidência (TI) para 10 mil doses apli-cadas. Resultados: A população em estudo foi de 274 pacientes, sendo 73% do sexo feminino, com média das idades de 39,8±14,5 anos. Foram aplicadas 197.001 doses no ano de 2021, o que resultou em uma TI geral de EAPV de 13,9. Houve 206 reações notificadas em pacientes imunizados com a AstraZeneca (TI=29,1), 43 com a Pfizer (TI=5,1), 18 com a Coronavac (TI=4,8) e sete com a Janssen (TI=13,8). Houve apenas sete casos classificados como graves (TI=0,3) e, destes, um paciente evoluiu com óbito, sem relação causal estabelecida. Conclusão: A incidência geral de eventos graves foi baixa, o que corrobora o perfil de segurança dos imunobiológicos disponíveis contra a COVID-19 (AU).

The mass availability of vaccines against the SARS-CoV-2 virus is the result of worldwide scientific efforts. However, insecurity and popular hesitation permeate the antivaccine movements. Objective: Analyze the profile of Post-Vaccine Adverse Events (PVAE) in the city of Tubarão, SC, Brazil, in 2021. Methodology: Cross-sectional epidemiological study with data from all standard PVAE notification forms in the city of Tubarão-SC in 2021. The variables analyzed were the epidemiological profile of the patient, the immunobiological administered, the type of event and the evolution of the cases. The incidence rate (IR) was calculated for 10,000 doses ap-plied. Results: The study population was 274 patients, 73% were female, with a mean age of 39.8±14.5 years. A total of 197,001 doses were applied in the year 2021, resulting in an overall IR of 13.9. There were 206 reactions reported in pa-tients immunized with AstraZeneca (IR=29.1), 43 with Pfizer (IR=5.1), 18 with Coro-navac (IR=4.8) and seven with Janssen (IR=13.8). There were only seven cases classified as severe (IR=0.3) and, of these, one patient died, with no causal rela-tionship established. Conclusion: The overall incidence of serious events was low, which corroborates the safety profile of available immunobiologicals against COVID-19

La región epididimaria de la paloma (columbia livia): análisis morfológico y morfométrico / The epididymal region of the pigeon (columba livia): morphological and morphometrical evaluation

La vía espermática extratesticular de la paloma está formada por los conductores eferentes proximales y distales, y Por el conducto epididimario. Los conductos eferentes están revestidos por epitelio pseudo-estratificado, estereocilado y el conducto Epididimario por epitelio columnar bajo, pseudo-estratificado. El análisis morfométrico demostró que los conductores eferentes proximales Poseen mayor diámetro medio entre los túbulos de la región epididimaria (X: 283,64 um); teniendo este hecho una probable implicancia Fisiológica en el proceso de reabsorción del fluido seminífero

Bone Paracoccidioidomycosis in an HIV-Positive Patient.

AIDS patients are vulnerable to infection by opportunistic microbes, including various fungi such as Pneumocystis carinii, Cryptococcus neoformans, Histoplasma capsulatum, Candida albicans and many others. However, the association of AIDS and infection with Paracoccidioides brasiliensis has been rarely recorded. We report a case of an HIV-positive patient with bone infection by this fungus with a clinical form not previously published. This clinical presentation included primarily a massive bone lesion, but it did not include the lymphatic and disseminated disease described in HIV-positive patients. The patient responded well to medical and surgical treatment. We suggest that patients with moderate, rather than severe, immunosuppression may have forms of paracoccidioidomycosis with a pathologic process intermediate to those seen in the immunologically normal host and the full AIDS syndrome.

Ultrastructure of oesophageal epithelium of pacu (piaractus mesopotamicus Holmberg, 1887)

El epitelio de revestimiento del esófago del pacú (Piaractus mesopotamicus), está constituido por cuatro tipos celulares: basales, intermediarias, superficiales y mucosas. Nuestras observaciones son comparadas con las realizadas en otros teleosteos. Se discuten las caracteristicas ultraestructurales de los distintos tipos celulares

[Usefulness of preoperative biliary drainage: comparison of therapeutic strategies]. / Sull'utilita' del drenaggio biliare preoperatorio: strategie terapeutiche a confronto.

This work shows the results obtained by the comparison between a period in which obstructive icterus was treated only surgically and a mixed period, based on endoscopic or endoscopic surgical treatment. In a period of 9 years (1979-87), 186 patients suffering from obstructive icterus were admitted into the 1st Division of General Surgery at Ospedale Maria Vittoria, Turin. In the first five years (1979-83) all the patients (78) were indistinctly operated after the usual diagnostic controls. In the following four years (1983-87) 62 out of 108 patients, considered as high-risk ones, underwent drainage by endoscopic way. In the high-risk patients, both neoplastic and not, morbidity rate, death rate and average stay in hospital were evidently lower after endoscopic or endoscopic-surgical treatment than after surgery alone. In conclusion, endoscopic pre-operating drainage in selected and/or high-risk patients greatly reduces perioperative complications and mortality.

[Traumatic rupture of the diaphragm]. / Rotture traumatiche del diaframma.

A survey based on 122 personal observations of traumatic rupture of diaphragm, involving stomach and spleen herniation into the chest, is presented. The importance of clinical symptoms for proper diagnosis and treatment is discussed, in relation to the different trends in the literature.

[Biliary drainage in neoplastic obstructive icterus]. / I drenaggi biliari nell'ittero ostruttivo neoplastico.

The authors consider the use of endoscopic or transhepatic bile drainage to regress jaundice and cholestasis before surgical treatment (radical or palliative) or like an alternative to it.

[Experimental porto-systemic diversion in the rat: a comparative analysis of technics and results]. / Le derivazioni porto sistemiche sperimentali nel ratto: analisi comparativa di tecniche e risultati.

A number of techniques for performing portacaval end-to-side and side-to-side pancreaticoduodenal and mesenterico-caval shunts in rats are described. These shunts, transposition and arterialization are valuable objects for training in microvascular surgery. Effects of shunts, liver function, hemodynamics, metabolic and neurological changes related to portal flow, liver metabolism, and portal pressure are compared.

[Diagnosis and therapy of splenic injuries]. / Diagnosi e terapia dei traumi splenici.

The purpose of this work is a critical revision of spleen traumatism treatment. We have examined 46 patients which we treated by total splenectomy. We examined the recent literature on spleen functions and we tried to punctualize the newest methods for conservative treatment of the spleen.

[Surgical therapy of recurrent varicocele]. / Terapia chirurgica del varicocele recidivo.

In the surgical treatment of recidivous varicocele, has been adopted in eight patients a personal technique that varies in some points from the Ivanissevich's one. Large dissection and resection of the spermatic vein in peritoneum back zone for 6-8 cm. length, prier ligature of all possible collaterals. In four cases has been applied the microsurgical technique, anastomosing the veins of the spermatic plexus to the saphena vein. Checks performed at distance of time haven't shown any relapsing case. The microsurgical technique should give the more immediate normalization of spermatogenesis.