1.
Org Biomol Chem
; 22(26): 5325-5332, 2024 Jul 03.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38874178
RESUMEN
In this paper, the hydrogenation of aldehydes and ketones using the RANEY® nickel catalyst was successfully applied for the synthesis of alcohol compounds without additional column chromatographic purification. This synthetic strategy features a wide range of substrates, excellent atom economy, high chemical discrimination and the use of a ligand-free catalytic system. Reactions were performed at room temperature in water providing alcohols in high yields and purity.