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Fetal Pediatr Pathol ; 30(6): 387-93, 2011.
Artículo en Inglés | MEDLINE | ID: mdl-22059458

RESUMEN

Preeclampsia is a syndrome characterized by hypertension and proteinuria. The aim of this study is to find the relationship between preeclampsia, asymmetric dimethyl arginine (ADMA), and the oxidant/antioxidant system. Twenty-one preeclamptic and 28 normal pregnant women were included in this study. In cord bloods, ADMA and oxidant/antioxidant parameters were measured. Asymmetric dimethyl arginine levels were significantly increased in preeclamptic pregnancies compared to the control group (p = 0.006). The activities of antioxidant enzymes and malondialdehyde levels were increased in the preeclamptic group compared to the control group (p < 0.001, p = 0.022, p < 0.001, p < 0.001, respectively). Development of endothelial dysfunction and oxidative stress may play a role in developing preeclampsia.


Asunto(s)
Arginina/análogos & derivados , Preeclampsia/sangre , Preeclampsia/etiología , Adulto , Antioxidantes/metabolismo , Arginina/sangre , Estudios de Casos y Controles , Citrulina/sangre , Femenino , Sangre Fetal , Humanos , Peroxidación de Lípido , Malondialdehído/sangre , Oxidantes/sangre , Estrés Oxidativo , Embarazo , Adulto Joven
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