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1.
Respir Med Case Rep ; 35: 101547, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35059285

RESUMEN

Lipid pneumonia is pneumonia due to aspiration or inhalation of various oily or fatty substances. It can be divided into exogenous and endogenous depending on the source of the lipids. In endogenous lipid pneumonia (ELP), lipid accumulates in the intra alveoli as a result of obstruction, chronic lung infection/disease, or a lipid storage disorder. This study presents a case of a 47 year-old man with a history of smoking, surgically repaired ventricular septal defect, pulmonary stenosis, and no history of lipid intake. He complained of worsened exertional dyspnea and a chronic non-productive cough with no signs and symptoms of infection. The patient was diagnosed with idiopathic endogenous lipid pneumonia after excluding any inflammatory or systemic disease as a possible cause. Open lung biopsy showed lipid-laden macrophages. Corticosteroids were the mainstay therapy with no radiological improvement, eventually death occurred due to pulmonary embolism.

2.
Avicenna J Med ; 2(4): 79-83, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23826553

RESUMEN

OBJECTIVE: Implementation of ventilator associated pneumonia (VAP) bundle as a performance improvement project in the critical care units for all mechanically ventilated patients aiming to decrease the VAP rates. MATERIALS AND METHODS: VAP bundle was implemented in 4 teaching hospitals after educational sessions and compliance rates along with VAP rates were monitored using statistical process control charts. RESULTS: VAP bundle compliance rates were steadily increasing from 33 to 80% in hospital 1, from 33 to 86% in hospital 2 and from 83 to 100% in hospital 3 during the study period. The VAP bundle was not applied in hospital 4 therefore no data was available. A target level of 95% was reached only in hospital 3. This correlated with a decrease in VAP rates from 30 to 6.4 per 1000 ventilator days in hospital 1, from 12 to 4.9 per 1000 ventilator days in hospital 3, whereas VAP rate failed to decrease in hospital 2 (despite better compliance) and it remained high around 33 per 1000 ventilator days in hospital 4 where VAP bundle was not implemented. CONCLUSION: VAP bundle has performed differently in different hospitals in our study. Prevention of VAP requires a multidimensional strategy that includes strict infection control interventions, VAP bundle implementation, process and outcome surveillance and education.

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