Light-Based Home-Use Hair Removal Devices: A Cross-Sectional Survey.

Background: The use of light-based home-use hair removal devices has seen a significant increase in the last decade all over the world. Home-based devices would be especially more relevant in the context of the COVID-19 pandemic, with patients having less access to laser hair removal in clinics. This survey attempted to evaluate the practices-related use of light-based home-use hair removal devices in our region and also to assess patient satisfaction related to the same. Materials and Methods: This was a cross-sectional survey using an electronic questionnaire. Results: Out of a total of 111 valid responses, 39 had used light-based home-use hair removal devices. The most common type used was intense pulse light-based devices. On a scale of 1-10, the average satisfaction with the product for hair removal was 6.07. Incidence of side effects was very low (only 4 out of 39 mentioned side effects), and the most common side effects mentioned were redness, "bumps," burns, and discoloration on the lased sites. Conclusions: The frequency of use of light-based home hair removal devices is quite high in our region. Patients seem to be satisfied with the same, and the incidence of side effects is low in our population.

Prevalence of dermatofibrosarcoma protuberans in Saudi Arabia over 24 years.: A retrospective single-institution study.

OBJECTIVES: To conduct a descriptive clinicopathological and demographic analysis of dermatofibrosarcoma protuberans among Saudi patients attending a tertiary care center in the eastern province of Saudi Arabia. METHODS: This retrospective, single-center study reviewed the medical records and pathology reports of Saudi patients attending a tertiary center (Johns Hopkins Aramco Health Care) in Dhahran, Saudi Arabia from 1995 to 2019 to identify all cases of dermatofibrosarcoma protuberans. Demographic and phenotypic data were also analyzed. RESULTS: Thirty-five Saudi patients were identified as having dermatofibrosarcoma protuberans. Females constituted 68.6% of patients. The trunk was the most common site of involvement (54.3%), followed by the lower extremities (34.3%), upper extremities (8.6%), and head and neck (2.9%). The mean tumor size was 2.9 cm (standard deviation: ±2.0). There was only one case of distant metastasis of fibrosarcomatous dermatofibrosarcoma protuberans. CONCLUSIONS: Dermatofibrosarcoma protuberans was not frequently encountered in Saudi patients in a tertiary center that treats approximately 187,668 patients. Dermatofibrosarcoma protuberans disease patterns and demographic data were similar to those reported worldwide. Further studies are required to characterize dermatofibrosarcoma protuberans in the Saudi population.

Self-Precautions among Dermatologists Managing HPV-Related Infections: Awareness and Current Practice of Dermatologists Practicing in Saudi Arabia.

Dermatologists are at risk of occupational exposures to human papilloma virus (HPV); however, the required precautions during each treatment modality of warts are not standardized. A self-administered online survey to investigate awareness and current practice of precautions during treatment of warts among dermatologists in Saudi Arabia was administered. A total of 228 responses were received. The most commonly used procedures for genital/other mucosal warts were liquid nitrogen (90%), electrocautery (57%), and in-clinic-administered podophyllin (51.3%). For cutaneous (non-genital) warts, the most commonly used methods for therapy were liquid nitrogen (95%) and electrocautery (77.6%). Of the respondents, 96% wore gloves while examining genital warts and 83.3% wore gloves while examining non-genital warts. The use of surgical masks during different procedures was variable from 27.7% to 76.7%. Only 38.6% always disinfected liquid nitrogen canister following use, while 49% always disinfected the electrocautery probe following use. Of the respondents, 34.65% had HPV infection, and of these, 55.7% developed warts during dermatology practice. There are variable precautions among dermatologists when dealing with HPV and further recommendations are warranted. As physicians, we gave our suggestions based on the literature review and our own opinions.

Prurigo pigmentosa following laparoscopic gastric sleeve.

Prurigo pigmentosa is an uncommon inflammatory skin disease predominately affecting young women. Clinically the disease presents with erythematous and urticarial papules arranged in a reticular pattern. Lesions heal with reticulated hyperpigmentation. Strict ketogenic diet is one of many factors that might trigger the disease. In this article, we present a case of prurigo pigmentosa following a complicated laparoscopic gastric sleeve with the resolution of the rash after improvement of the patient's diet.

Congenital Hypotrichosis and Congenital Atrichia.

A wide range of conditions can present with congenital hypotrichoses/atrichia. Awareness of these conditions can help in the proper and timely diagnosis and counseling of affected families, and in some cases avoid unnecessary investigations. The rapid growth in genetic analysis of diseases has also led to an increased knowledge of the genetic and molecular basis of many of these conditions. This contribution briefly reviews updates on some of the most common conditions associated with congenital hypotrichosis/atrichia.

Precalcaneal congenital fibrolipomatous hamartoma.

Precalcaneal congenital fibrolipomatous hamartoma is a benign condition of infancy that is sometimes misdiagnosed due to lack of reports in the literature. Lesions usually present with painless, non-pruritic, skin colored bilateral, solitary, symmetric nodules located in the middle of the heels. The lesions gradually increase in size and then regress by the age of 2 to3 years old.

Cantharidin in Dermatology.

Cantharidin is natural toxin produced by the blistering beetle. It has both vesicant and keratolytic features by inducing acanthloysis through targeting the desmosomal dense plaque, leading to detachment of the desmosomes from the tonofilaments. There are two available liquid preparations for dermatologic use, Canthacur (0.7% cantharidin) and Canthacur PS (1% cantharidin 30%/salicylic acid/2% podophylotoxin). The former preparation is indicated for the treatment of common warts, periungual warts, and molluscum contagiosum, while the more potent latter preparation is indicated only for plantar warts. Both preparations provide painless applications with outcomes similar to other treatment modalities for warts and molluscum contagiosum; however, neither is approved by the Food and Drug Administration (FDA). The lack of FDA approval could be related to its toxic effects following oral ingestion, which include ulceration of the gastrointestinal and genitourinary tracts, along with electrolyte and renal function disturbance in humans and animals. The mechanism of action, dermatologic indications, application techniques, and complications of cantharidin preparations are discussed.

Pattern of skin cancer among Saudi patients attending a tertiary care center in Dhahran, Eastern Province of Saudi Arabia. A 20-year retrospective study.

Skin cancer is the ninth most common malignancy in Saudi Arabia. It represented 3.2% of all newly diagnosed cancer cases in the year 2010. The aim of this study was to determine the epidemiology of skin cancer in relation to age, sex, and anatomic location among Saudi patients attending the Johns Hopkins Aramco Healthcare center in Dhahran, Eastern province of Saudi Arabia. We retrospectively reviewed the surgical pathology records of Saudi nationals from 1995 to 2014 at the Johns Hopkins Aramco Healthcare center, which directly provides for the healthcare needs of Saudi Aramco company employees and dependents in the Eastern Province of Saudi Arabia. Tumor metastases to skin, skin involvement by primary breast carcinoma, and B-cell leukemia/lymphoma with secondary involvement by skin were excluded. The total number of primary skin tumors was 204. The commonest cutaneous malignancies were basal cell carcinoma (36%) followed by squamous cell carcinoma (23%), with the head and neck being the commonest location for both tumors. Mycosis fungoides (MF) was the third most common malignancy (11%). Malignant melanoma was the fourth commonest skin malignancy (7%) with the lower extremities being the commonest location. The four most common skin cancers in our tertiary center in the Eastern Province of Saudi Arabia were squamous cell carcinoma, basal cell carcinoma, MF, and malignant melanoma. Other regions of Saudi Arabia report a similar pattern of skin cancers as our center, with MF having a higher frequency at our center.

Angiosarcoma at the site of nonfunctioning arteriovenous fistula in a kidney transplant recipient.

Angiosarcoma is a rare malignant neoplasm of the endothelial cells of blood vessels or lymphatics. We report a case of a 46-year-old male patient with a kidney transplant who developed epithelioid angiosarcoma at the site of a nonfunctioning arteriovenous fistula in the antecubital fossa 3 years after renal transplantation. The patient had skin, soft tissue, and bone metastasis on presentation. He died of systemic metastasis with respiratory failure.

Nail-Patella Syndrome: A Report of a Saudi Arab Family With an Autosomal Recessive Inheritance.

BACKGROUND: Nail-patella syndrome (NPS) is an autosomal dominant disorder with a variable interfamilial and intrafamilial clinical expressivity and penetrance. It is caused by loss-of-function heterozygous mutation in the LIM-homeodomain transcription factor (LMX1B) located on chromosome 9q. The pleiotropic LMB1X gene, a member of the homeogene family, is involved in the development of glomerular basement membrane, dorsoventral limb structures, along with the nails and the anterior segment of the eye. OBJECTIVE: Here, we report a Saudi Arab consanguineous family with 2 affected sisters presented with the typical nail changes of NPS. METHODS: DNA samples were collected from the sisters and their parents after consent. RESULTS: Both sisters were found to be homozygous for a previously described disease-causing mutation (c.268C>T) at the (LMX1B) gene. Both of the phenotypically normal parents were confirmed to be heterozygous for the same mutation. CONCLUSION: This finding supports the autosomal recessive mode of inheritance in this family.

Granular Cell Tumor on the Chest of a 9-Year-Old Female: Case Report and a Retrospective Analysis.

BACKGROUND: Granular cell tumor is a benign tumor originating from Schwann cells. Children and adolescents are rarely affected. We report a 9-year-old female who presented with a cutaneous granular cell tumor on the chest. OBJECTIVE: To determine the incidence of granular cell tumor and proportion of tumors seen in the pediatric population at our center. METHODS: We retrospectively reviewed the surgical pathology records from 1997 to 2014 at our center. RESULTS: The incidence of granular cell tumor is five cases per million person-years (95% CI 3-8). Of the 18 cases, 9 cases occurred in the pediatric population. CONCLUSION: Fifty percent of granular cell tumor cases diagnosed at our center occurred in the pediatric population. Granular cell tumor may not be as rare as we expect in the pediatric population.

Sclerotic atrophic plaques associated with a tattoo.

Lichen sclerosus is a chronic inflammatory disease, usually of the anogenital area, that causes intractable itching and soreness. Less commonly, it may have extragenital involvement in 15 to 20% of cases. Lichen sclerosus has been reported at sites of injury as a Koebner phenomenon. We report a case of lichen sclerosus at the site of a tattoo with simultaneous genital involvement.

Amyloidosis cutis dyschromia: a rare form of primary cutaneous amyloidosis.

Amyloidosis cutis dyschromia is a rare form of primary cutaneous amyloidosis. Amyloid deposition in the skin occurs without systemic manifestations and produces hypopigmented and hyperpigmented macules. A 19-year-old woman is presented with progression of this condition over 16 years.

Pigmented Bowen's disease of the penis and scrotum in a patient with AIDS.

Patients with HIV have higher risk of developing squamous cell carcinoma of the skin given the increased risk of HPV infection, which alters cell proliferation and apoptosis [1]. Pigmented Bowen's disease is an uncommon form of squamous cell carcinoma in-situ characterized by pigmented lesions that can clinically mimic superficial spreading melanoma, pigmented basal cell carcinoma, melanocytic nevus, Bowenoid papulosis, and seborrheic keratosis.

Paraneoplastic dermatoses associated with gynecologic and breast malignancies.

UNLABELLED: Paraneoplastic dermatoses are a heterogeneous group of skin disorders that manifest an underlying internal malignancy. Early recognition of these cutaneous hallmarks offers an opportunity for early diagnosis, treatment of the internal malignancy and monitoring for tumor recurrence. The 9 most common paraneoplastic and metastatic cutaneous manifestations of malignancies found in women with gynecologic or breast disease are reviewed including a review of multicentric reticulohistiocytosis, dermatomyositis, malignant acanthosis nigricans, erythema gyratum repens, hypertrichosis lanuginosa acquisita, Sweet syndrome, Paget disease, extramammary Paget disease, and Sister Mary Joseph nodule. TARGET AUDIENCE: General obstetricians & gynecologists, reproductive endocrinology & infertility specialists, radiologists. LEARNING OBJECTIVES: After completion of this educational activity, the participant should be better able to identify cutaneous manifestations of gynecologic malignancies, evaluate patients with a thorough workup to screen those who have dermatoses suggestive of malignancy and assess patients with malignancy for the opportunity of early diagnosis and appropriate treatment.