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BACKGROUND: Assessing the effects of compromised vision in laparoscopic and robotic procedures is crucial to understanding its impact on surgical practice and patient safety. Our aim was to examine the impact of operative vision compromise (OViC) on surgeons' practice. METHODS: Intraoperative workload was qualitatively assessed using the NASA-TLX score. Participants included internationally trained surgeons performing laparoscopic sleeve gastrectomy (LSG) procedures. Video recordings of LSG procedures were quantitatively analyzed to assess OViC event frequency and duration to determine their influence on procedural time and surgical flow in a secondary care center. Surgeons' views on OViC were assessed using a custom survey. Cost analysis of basic expenditures was performed. RESULTS: Among 109 participants, the overall NASA-TLX score for OViC was 71.7, indicating a high workload. Out of 81 LSG procedures, 77 experienced at least one lens fouling episode, resulting in 471 OViC events, including 371 lens cleaning occurrences. Significant positive correlations were found between total procedure time and several OViC variables. Compromised vision accounted for 19.3% of total operative time. Lens cleaning constituted 2.5% of the total operative time. In nine (11%) cases, lens cleaning added an average of 7 minutes per procedure, with the most severe case adding 15 minutes of operative time. The majority of surgeons (94%) found OViC to impair their performance and compromise patient safety, with 61% reporting witnessing surgical errors or complications directly attributable to OViC. CONCLUSIONS: OViC was linked to increased procedure time, surgical flow disruptions, elevated surgeon workload, cognitive burden, and frustration, and potential patient safety concerns. These findings emphasize the need for innovative solutions to mitigate operative vision compromise, thereby potentially minimizing errors and enhancing operative outcomes.
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Background: Nonmelanotic skin cancer (NMSC) refers to cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma. There have been many factors linked with the development of cSCC; however, ultraviolet radiation is the most notable culprit. Mutations in RAS signaling genes, the CDKN2A gene, and genes encoding components of the NOTCH signaling pathways increase the risk of developing cSCC. Many therapeutic approaches are available for cSCC, including chemotherapy, radiation therapy, targeted therapy, immunotherapy, and topical treatment. As cSCC affects millions of people worldwide, there is increasing demand to find more minimally invasive treatment approaches, such as hyaluronic acid therapy. Methods: A narrative literature review was conducted on the available literature regarding NMSC, and various treatment strategies were identified. Conclusions: Recent research investigating whether long-lived cancer-resistant species could yield any potential clues against skin carcinogenesis has highlighted naked mole rats (Heterocephalus glaber). One of the proposed mechanisms associated with this tumor resistance has been the accumulation of high-molecular-weight hyaluronic acid (HMWHA) in the epidermis. Researchers were able to conclude that the CD44/HMWHA interaction mediates cancer cell apoptosis and restricts cell cycle progression as a mechanism of cancer resistance in naked mole rats.
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INTRODUCTION: Cadaveric fresh frozen cartilage provides an enticing alternative to traditional autologous cartilage grafts. This review provides a systematic analysis of existing literature on the use of fresh frozen rib for in rhinoplasties and focuses on clinical and aesthetic outcomes. METHODS: The methodology was designed and registered in the PROSPERO database (CRD42023447166). The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guideline was used to perform this systematic review. RESULTS: Four articles were included, with a total of 554 patients. A total of 477 patients were female (86%). Mean age ranged between 35.8 and 40.6. Mean follow-up ranged from 12.2 to 20.3 months. Only one article had a suitable control (with autologous rib graft). Pooled complications rates were low. Infection occurred in 12 patients (2%), warping in 8 patients (1.4%) and resorption in 3 patients (0.5%). CONCLUSION: Fresh frozen cartilage may be a safe and reliable alternative to autologous rib grafts. Complication rates were comparable to previous systematic reviews of autologous graft and irradiated allograft. Overall, patients reported high satisfaction rates with low rates of revision procedures. Further studies are required to assess both clinical and cost effectiveness against the current gold standard (autologous graft). LEVEL OF EVIDENCE III: Rhinoplasty. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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BACKGROUND: Dermal fillers have created a multi-billion-dollar industry. They are the second most popular form of injectable, as they primarily address volume loss, augmentation, and provide immediate results. The most popular form includes hyaluronic acid-based fillers, however, alternatives exist. OBJECTIVE: To create clinical charts to help with filler selection, injection, and addressing common complications. METHODS: The current literature and expert opinions form our two senior authors were used to create a numerical and color-coded chart based on G-prime for filler selection, as well as an anatomical table with current recommendations and pearls. We have also included a safety table with current clinical recommendation to deal with common filler-related complications. CONCLUSION: Fillers are a safe and reliable method to achieve augmentation. Filler selection in various anatomical planes plays a significant role in achieving favorable results.