1.
Chem Commun (Camb)
; 51(6): 1066-9, 2015 Jan 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-25435252
RESUMEN
Selective inhibitors of voltage-activated K(+) channels are needed for the treatment of multiple sclerosis. In this work it was discovered that porphyrins bearing 2-4 carbon alkyl ammonium side chains predominantly blocked the Kv1.1 current whilst Kv1.2 was susceptible to a porphyrin bearing polyamine side chains.