[Glomerular permeability for serum proteins in different morphological types of primary chronic glomerulopathy]. / Klubochkovaia pronitsaemost' dlia syvorotochnykh belkov pri paznykh morfologicheskikh tipakh pervichnoi khronicheckoi glomerulopatii.

Membranous glomerulonephritis (MGN), mesangiocapillary (MCGN), membranoproliferative glomerulonephritis (MPGN) and focal segmental sclerosis or hyalinosis (FSSH) were studied for glomerular filter permeability to serum albumins, IgA and IgG. In MGN the permeability for large-molecular globulins is not dependent on that for albumin, permeabilities for the globulins appeared correlated. In MPGN permeability for IgG depends on albumins permeability, correlations between that for IgA and IgG are similar to relevant findings in MGN. In MCGN glomerular permeability for IgA depends on that for albumins, and IgG depends on IgA permeability. In FSSH better albumin permeability implies increased permeability for both globulins, while enhanced permeability for IgA entails the same trend for albumins and IgG. Variable permeability of the glomerular filter for serum proteins in different morphological forms of chronic glomerulopathy may result from dissimilar defects in diverse layers of the filter and in interaction of basal membrane structures with cells responsible for glomerular impermeability for serum proteins.

[A comparative evaluation of the electric impulse treatment of atrial fibrillation based on the data from 2 clinics. 2. The late results]. / Sravnitel'naia otsenka élektroimpul'snogo lecheniia mertsatel'noi aritmii na materiale dvukh klinik. Soobshchenie 2. Otdalennye rezul'taty.

Long-term results of electroimpulse treatment for cardiac fibrillation in 1292 patients performed in cardiological clinics of Moscow and Kaunas have been compared. It is shown that more strict selection, longer preparation for the impulse exposure may secure a significant decrease in the number of the fibrillation recurrences both 1 and 6 months after recovery of the normal rhythm.

[A method of choosing maintenance anti-arrhythmia therapy after sinus rhythm restoration in patients with a permanent form of atrial fibrillation]. / Metod vybora podderzhivaiushchei antiaritmicheskoi terapii posle vosstanovleniia sinusovogo ritma u bol'nykh s postoiannoi formoi mertsatel'noi aritmii.

The authors suggest a new method of choice of the drug (quinidine or cordarone) for the maintenance antiarrhythmic therapy after sinus rhythm recovery in patients with permanent atrial fibrillation, in patients with rheumatic heart disease and coronary heart disease. The method is based on the formalized prediction of the results of cardioversion and on the distinguishing groups with a good and bad prognosis. In the former group, both drugs can be administered, in the latter group, it is desirable that cordarone may be used.

[A comparison of the efficacy of quinidine and kordaron as agents to stabilize the recovered sinus rhythm in patients with the permanent form of atrial fibrillation]. / Sravnenie éffektivnosti khinidina i kordarona kak sredstv stabilizatsii vosstanovlennogo sinusovogo ritma u bol'nykh s postoiannoi formoi mertsatel'noi aritmii.

The efficacy of chinidine and cordarone as agents preventing the recurrence of the disturbed sinus rhythm was studied and compared on a material of 459 patients with permanent atrial fibrillation eliminated by electropulse therapy. The sinus rhythm was preserved significantly better in a group of patients given cordarone as a preventive agent, which is confirmed with the aid of a multidimensional statistical analysis as well as an analysis of "competing hypotheses".

[The prognosis of the late results of electroimpulse therapy for atrial fibrillation in ischemic heart disease patients]. / Prognozirovanie otdalennykh rezul'tatov élektroimpul'snoi terapii mertsatel'noi aritmii u bol'nykh ishemicheskoi bolezn'iu serdtsa.

The deciding rule has been derived of predicting long-term results of electropulse therapy of permanent atrial fibrillation in patients with coronary heart disease. During checking with the prospective material, the prediction as regards preservation of the sinus rhythm up to 6 months turned out correct in 93% of cases. The deciding rule is based on the commonly available clinical parameters. Work with that rule does not require the use of computers. Prognosis obtained with the aid of the given rule appeared significantly more accurate than that determined by the physician specialized in the field of cardiology.

[Selection of the information for solving medical diagnostic problems with "diagnostic games" (the example of predicting the time of sinus rhythm maintenance after eliminating atrial fibrillation)]. / Otbor informatsii dlia resheniia zadach meditsinskoi diagnostiki s pomoshch'iu "diagnosticheskikh igr" (na primere zadachi prognozirovaniia sroka sokhraneniia sinusovogo ritma posle ustraneniia mertsatel'noi aritmii).

A new method is proposed for data selection with respect to solving medical diagnosis problems. It reduces the scope of information, leaving for further processing only the facts the physician actually needs for problem-solving. The protocols of "diagnostic games" reflect the physician's mental process and can be used in the development of a physician model.

[Prognosis of the outcome of macrofocal myocardial infarct with the aid of the recognition program]. / Prognozirovanie iskhoda krupnoochagovogo infarkta miokarda s pomoshch'iu programmy uznavaniia.

Methods used in solving the problem of prognosing favourable or unfavourable outcomes of a transmural (or macrofocal) myocardial infarction, based on the data covering the first 3 days of the hospital stay for patients admitted to it not later than 2 days after the onset of myocardial infarction and who did not develop during this period extremely serious complications, are described. The prognosis covered the entire period of the institutional treatment of the patients. The data underwent computer processing. The obtained solution rule was checked on 178 patients. In 143 of them the machine prognosis proved favourable with only 2 of these patients having met a sudden death. The forecast turned out unfavourable in 35 cases and 16 of these patients died. The machine made prognosis is of a great help in pronouncing medical judgments.