DSCNet: Deep Skip Connections-Based Dense Network for ALL Diagnosis Using Peripheral Blood Smear Images.

Acute lymphoblastic leukemia (ALL) is a life-threatening hematological malignancy that requires early and accurate diagnosis for effective treatment. However, the manual diagnosis of ALL is time-consuming and can delay critical treatment decisions. To address this challenge, researchers have turned to advanced technologies such as deep learning (DL) models. These models leverage the power of artificial intelligence to analyze complex patterns and features in medical images and data, enabling faster and more accurate diagnosis of ALL. However, the existing DL-based ALL diagnosis suffers from various challenges, such as computational complexity, sensitivity to hyperparameters, and difficulties with noisy or low-quality input images. To address these issues, in this paper, we propose a novel Deep Skip Connections-Based Dense Network (DSCNet) tailored for ALL diagnosis using peripheral blood smear images. The DSCNet architecture integrates skip connections, custom image filtering, Kullback-Leibler (KL) divergence loss, and dropout regularization to enhance its performance and generalization abilities. DSCNet leverages skip connections to address the vanishing gradient problem and capture long-range dependencies, while custom image filtering enhances relevant features in the input data. KL divergence loss serves as the optimization objective, enabling accurate predictions. Dropout regularization is employed to prevent overfitting during training, promoting robust feature representations. The experiments conducted on an augmented dataset for ALL highlight the effectiveness of DSCNet. The proposed DSCNet outperforms competing methods, showcasing significant enhancements in accuracy, sensitivity, specificity, F-score, and area under the curve (AUC), achieving increases of 1.25%, 1.32%, 1.12%, 1.24%, and 1.23%, respectively. The proposed approach demonstrates the potential of DSCNet as an effective tool for early and accurate ALL diagnosis, with potential applications in clinical settings to improve patient outcomes and advance leukemia detection research.

Multidisiplinary design optimization of a power generation system based on waste energy recovery from an internal combustion engine using organic Rankine cycle and thermoelectric generator.

The research paper mainly deals with waste heat recovery from internal combustion engines (ICE) using the organic Rankine cycle (ORC) and Thermoelectric generator (TEG). Simultaneously recovering the wasted heat of both exhaust gases and coolant, a novel configuration named two-stage is proposed. Then a comprehensive thermo-economic analysis and optimization are conducted. Produced power and total cost rate are selected as the objective function of the optimization. Also, the first and second stage pressures of the ORC system are considered as decision variables. Finally, a sensitivity analysis is performed to study the effect of expander inlet temperature, pumps isentropic efficiency, and expander isentropic efficiency on the objective function.

The roles of artificial intelligence techniques for increasing the prediction performance of important parameters and their optimization in membrane processes: A systematic review.

Membrane-based separation processes has been recently of significant global interest compared to other conventional separation approaches due to possessing undeniable advantages like superior performance, environmentally-benign nature and simplicity of application. Computational simulation of fluids has shown its undeniable role in modeling and simulation of numerous physical/chemical phenomena including chemical engineering, chemical reaction, aerodynamics, drug delivery and plasma physics. Definition of fluids can be occurred using the Navier-Stokes equations, but solving the equations remains an important challenge. In membrane-based separation processes, true perception of fluid's manner through disparate membrane modules is an important concern, which has been significantly limited applying numerical/computational procedures such s computational fluid dynamics (CFD). Despite this noteworthy advantage, the optimization of membrane processes using CFD is time-consuming and expensive. Therefore, combination of artificial intelligence (AI) and CFD can result in the creation of a promising hybrid model to accurately predict the model results and appropriately optimize membrane processes and phase separation. This paper aims to provide a comprehensive overview about the advantages of commonly-employed ML-based techniques in combination with the CFD to intelligently increase the optimization accuracy and predict mass transfer and the unfavorable events (i.e., fouling) in various membrane processes. To reach this objective, four principal strategies of AI including SL, USL, SSL and ANN were explained and their advantages/disadvantages were discussed. Then after, prevalent ML-based algorithm for membrane-based separation processes. Finally, the application potential of AI techniques in different membrane processes (i.e., fouling control, desalination and wastewater treatment) were presented.

Comparing machine-learning-based black box techniques and white box models to predict rainfall-runoff in a northern area of Iraq, the Little Khabur River.

The rainfall-runoff process is one of the most complex hydrological phenomena. Estimating runoff in the basin is one of the main conditions for planning and optimal use of rainfall. Using machine learning models in various sciences to investigate phenomena for which statistical information is available is a helpful tool. This study investigates and compares the abilities of HEC-HMS and TOPMODEL as white box models and adaptive neural fuzzy inference system (ANFIS) and gene expression programming (GEP) as black box models in rainfall-runoff simulation using 5-year statistical data. Using the inputs of rainfall and temperature of the previous day and discharge in the steps of the previous 2 days reduced the prediction error of both models. Examining the role of different parameters in improving the accuracy of simulations showed that the temperature as an effective parameter in cold months reduces the amount of prediction error. A comparison of R2, RMSE, and MBE showed that black box models are more effective forecasting tools. Among the black box models, the ANFIS model with R2 = 0.82 has performed better than the GEP model with R2 = 0.76. For white box models, the HEC-HMS and TOPMODEL had R2 equal to 0.3 and 0.25, respectively.

5G standards for the Industry 4.0 enabled communication systems using artificial intelligence: perspective of smart healthcare system.

The emergence of the Industry 4.0 revolution to upgrade the Internet of Things (IoT) standards provides the prominence outcomes for the future wireless communication systems called 5G. The development of 5G green communication systems suffers from the various challenges to fulfill the requirement of higher user capacity, network speed, minimum cost, and reduced resource consumption. The use of 5G standards for Industry 4.0 applications will increase data rate performance and connected device's reliability. Since the arrival of novel Covid-19 disease, there is a higher demand for smart healthcare systems worldwide. However, designing the 5G communication systems has the research challenges like optimum resource utilization, mobility management, cost-efficiency, interference management, spectral efficiency, etc. The rapid development of Artificial Intelligence (AI) across the different formats brings performance enhancement compared to conventional techniques. Therefore, introducing the AI into 5G standards will optimize the performances further considering the various end-user applications. We first present the survey of the terms like 5G standard, Industry 4.0, and some recent works for future wireless communications. The purpose is to explore the current research problems using the 5G technology. We further propose the novel architecture for smart healthcare systems using the 5G and Industry 4.0 standards. We design and implement that proposed model using the Network Simulator (NS2) to investigate the current 5G methods. The simulation results show that current 5G methods for resource management and interference management suffer from the challenges like performance trade-offs.

Federated-Learning Based Privacy Preservation and Fraud-Enabled Blockchain IoMT System for Healthcare.

These days, the usage of machine-learning-enabled dynamic Internet of Medical Things (IoMT) systems with multiple technologies for digital healthcare applications has been growing progressively in practice. Machine learning plays a vital role in the IoMT system to balance the load between delay and energy. However, the traditional learning models fraud on the data in the distributed IoMT system for healthcare applications are still a critical research problem in practice. The study devises a federated learning-based blockchain-enabled task scheduling (FL-BETS) framework with different dynamic heuristics. The study considers the different healthcare applications that have both hard constraint (e.g., deadline) and resource energy consumption (e.g., soft constraint) during execution on the distributed fog and cloud nodes. The goal of FL-BETS is to identify and ensure the privacy preservation and fraud of data at various levels, such as local fog nodes and remote clouds, with minimum energy consumption and delay, and to satisfy the deadlines of healthcare workloads. The study introduces the mathematical model. In the performance evaluation, FL-BETS outperforms all existing machine learning and blockchain mechanisms in fraud analysis, data validation, energy and delay constraints for healthcare applications.

Integration of Healthcare 4.0 and blockchain into secure cloud-based electronic health records systems.

Since the last decade, cloud-based electronic health records (EHRs) have gained significant attention to enable remote patient monitoring. The recent development of Healthcare 4.0 using the Internet of Things (IoT) components and cloud computing to access medical operations remotely has gained the researcher's attention from a smart city perspective. Healthcare 4.0 mainly consisted of periodic medical data sensing, aggregation, data transmission, data sharing, and data storage. The sensitive and personal data of patients lead to several challenges while protecting it from hackers. Therefore storing, accessing, and sharing the patient medical information on the cloud needs security attention that data should not be compromised by the authorized user's components of E-healthcare systems. To achieve secure medical data storage, sharing, and accessing in cloud service provider, several cryptography algorithms are designed so far. However, such conventional solutions failed to achieve the trade-off between the requirements of EHR security solutions such as computational efficiency, service side verification, user side verifications, without the trusted third party, and strong security. Blockchain-based security solutions gained significant attention in the recent past due to the ability to provide strong security for data storage and sharing with the minimum computation efforts. The blockchain made focused on bitcoin technology among the researchers. Utilizing the blockchain which secure healthcare records management has been of recent interest. This paper presents the systematic study of modern blockchain-based solutions for securing medical data with or without cloud computing. We implement and evaluate the different methods using blockchain in this paper. According to the research studies, the research gaps, challenges, and future roadmap are the outcomes of this paper that boost emerging Healthcare 4.0 technology.

Hybrid wavelet-gene expression programming and wavelet-support vector machine models for rainfall-runoff modeling.

It is critical to use research methods to collect and regulate surface water to provide water while avoiding damage. Following accurate runoff prediction, principled planning for optimal runoff is implemented. In recent years, there has been an increase in the use of machine learning approaches to model rainfall-runoff. In this study, the accuracy of rainfall-runoff modeling approaches such as support vector machine (SVM), gene expression programming (GEP), wavelet-SVM (WSVM), and wavelet-GEP (WGEP) is evaluated. Python is used to run the simulation. The research area is the Yellow River Basin in central China, and in the west of the region, the Tang-Nai-Hai hydrometric station has been selected. The train state data ranges from 1950 to 2000, while the test state data ranges from 2000 to 2020. The analysis looks at two different types of rainy and non-rainy days. The WGEP simulation performed best, with a Nash-Sutcliffe efficiency (NSE) of 0.98, while the WSVM, GEP, and SVM simulations performed poorly, with NSEs of 0.94, 0.89, and 0.77, respectively. As a result, combining hybrid methods with wavelet improved simulation accuracy, which is now the highest for the WGEP method.

Integrated Design of Optimized Weighted Deep Feature Fusion Strategies for Skin Lesion Image Classification.

This study mainly focuses on pre-processing the HAM10000 and BCN20000 skin lesion datasets to select important features that will drive for proper skin cancer classification. In this work, three feature fusion strategies have been proposed by utilizing three pre-trained Convolutional Neural Network (CNN) models, namely VGG16, EfficientNet B0, and ResNet50 to select the important features based on the weights of the features and are coined as Adaptive Weighted Feature Set (AWFS). Then, two other strategies, Model-based Optimized Weighted Feature Set (MOWFS) and Feature-based Optimized Weighted Feature Set (FOWFS), are proposed by optimally and adaptively choosing the weights using a meta-heuristic artificial jellyfish (AJS) algorithm. The MOWFS-AJS is a model-specific approach whereas the FOWFS-AJS is a feature-specific approach for optimizing the weights chosen for obtaining optimal feature sets. The performances of those three proposed feature selection strategies are evaluated using Decision Tree (DT), Naïve Bayesian (NB), Multi-Layer Perceptron (MLP), and Support Vector Machine (SVM) classifiers and the performance are measured through accuracy, precision, sensitivity, and F1-score. Additionally, the area under the receiver operating characteristics curves (AUC-ROC) is plotted and it is observed that FOWFS-AJS shows the best accuracy performance based on the SVM with 94.05% and 94.90%, respectively, for HAM 10000 and BCN 20000 datasets. Finally, the experimental results are also analyzed using a non-parametric Friedman statistical test and the computational times are recorded; the results show that, out of those three proposed feature selection strategies, the FOWFS-AJS performs very well because its quick converging nature is inculcated with the help of AJS.

Mathematical Modeling and Control of COVID-19 Using Super Twisting Sliding Mode and Nonlinear Techniques.

Since the outbreak of the COVID-19 epidemic, several control strategies have been proposed. The rapid spread of COVID-19 globally, allied with the fact that COVID-19 is a serious threat to people's health and life, motivated many researchers around the world to investigate new methods and techniques to control its spread and offer treatment. Currently, the most effective approach to containing SARS-CoV-2 (COVID-19) and minimizing its impact on education and the economy remains a vaccination control strategy, however. In this paper, a modified version of the susceptible, exposed, infectious, and recovered (SEIR) model using vaccination control with a novel construct of active disturbance rejection control (ADRC) is thus used to generate a proper vaccination control scheme by rejecting those disturbances that might possibly affect the system. For the COVID-19 system, which has a unit relative degree, a new structure for the ADRC has been introduced by embedding the tracking differentiator (TD) in the control unit to obtain an error signal and its derivative. Two further novel nonlinear controllers, the nonlinear PID and a super twisting sliding mode (STC-SM) were also used with the TD to develop a new version of the nonlinear state error feedback (NLSEF), while a new nonlinear extended state observer (NLESO) was introduced to estimate the system state and total disturbance. The final simulation results show that the proposed methods achieve excellent performance compared to conventional active disturbance rejection controls.

Classification of Electrocardiography Hybrid Convolutional Neural Network-Long Short Term Memory with Fully Connected Layer.

Electrocardiography (ECG) is a technique for observing and recording the electrical activity of the human heart. The usage of an ECG signal is common among clinical professionals in the collection of time data for the examination of any rhythmic conditions associated with a subject. The investigation was carried out in order to computerize the assignment by exhibiting the issue using encoder-decoder techniques, creating the information that was simply typical of it, and utilising misfortune appropriation to anticipate standard or anomalous information. On a broad variety of applications such as voice recognition and prediction, the long short-term memory (LSTM) fully connected layer (FCL) and the two convolutional neural networks (CNNs) have shown superior performance over deep learning networks (DLNs). DNNs are suitable for making high points for a more divisible region and CNNs are suitable for reducing recurrence types, LSTMs are appropriate for temporary displays, in the same way as CNNs are appropriate for reducing recurrence types. The CNN, LSTM, and DNN algorithms are acceptable for viewing. The complementarity of DNNs, CNNs, and LSTMs was investigated in this research by bringing them all together under the single architectural company. The researchers got the ECG data from the MIT-BIH arrhythmia database as a result of the investigation. Our results demonstrate that the approach proposed may expressively describe ECG series and identify abnormalities via scores that outperform existing supervised and unsupervised methods in both the short term and long term. The LSTM network and FCL additionally demonstrated that the unbalanced datasets associated with the ECG beat detection problem could be consistently resolved and that they were not susceptible to the accuracy of ECG signals. It is recommended that cardiologists employ the unique technique to aid them in performing reliable and impartial interpretation of ECG data in telemedicine settings.

Rider weed deep residual network-based incremental model for text classification using multidimensional features and MapReduce.

Increasing demands for information and the rapid growth of big data have dramatically increased the amount of textual data. In order to obtain useful text information, the classification of texts is considered an imperative task. Accordingly, this article will describe the development of a hybrid optimization algorithm for classifying text. Here, pre-processing was done using the stemming process and stop word removal. Additionally, we performed the extraction of imperative features and the selection of optimal features using the Tanimoto similarity, which estimates the similarity between features and selects the relevant features with higher feature selection accuracy. Following that, a deep residual network trained by the Adam algorithm was utilized for dynamic text classification. Dynamic learning was performed using the proposed Rider invasive weed optimization (RIWO)-based deep residual network along with fuzzy theory. The proposed RIWO algorithm combines invasive weed optimization (IWO) and the Rider optimization algorithm (ROA). These processes are carried out under the MapReduce framework. Our analysis revealed that the proposed RIWO-based deep residual network outperformed other techniques with the highest true positive rate (TPR) of 85%, true negative rate (TNR) of 94%, and accuracy of 88.7%.

RAPCHI: Robust authentication protocol for IoMT-based cloud-healthcare infrastructure.

With the fast growth of technologies like cloud computing, big data, the Internet of Things, artificial intelligence, and cyber-physical systems, the demand for data security and privacy in communication networks is growing by the day. Patient and doctor connect securely through the Internet utilizing the Internet of medical devices in cloud-healthcare infrastructure (CHI). In addition, the doctor offers to patients online treatment. Unfortunately, hackers are gaining access to data at an alarming pace. In 2019, 41.4 million times, healthcare systems were compromised by attackers. In this context, we provide a secure and lightweight authentication scheme (RAPCHI) for CHI employing Internet of medical Things (IoMT) during pandemic based on cryptographic primitives. The suggested framework is more secure than existing frameworks and is resistant to a wide range of security threats. The paper also explains the random oracle model (ROM) and uses two alternative approaches to validate the formal security analysis of RAPCHI. Further, the paper shows that RAPCHI is safe against man-in-the-middle and reply attacks using the simulation programme AVISPA. In addition, the paper compares RAPCHI to related frameworks and discovers that it is relatively light in terms of computation and communication. These findings demonstrate that the proposed paradigm is suitable for use in real-world scenarios.

AI-driven adaptive reliable and sustainable approach for internet of things enabled healthcare system.

Artificial Intelligence (AI) driven adaptive techniques are viable to optimize the resources in the Internet of Things (IoT) enabled wearable healthcare devices. Due to the miniature size and ability of wireless data transfer, Body Sensor Networks (BSNs) have become the center of attention in current medical media technologies. For a long-term and reliable healthcare system, high energy efficiency, transmission reliability, and longer battery lifetime of wearable sensors devices are required. There is a dire need for empowering sensor-based wearable techniques in BSNs from every aspect i.e., data collection, healthcare monitoring, and diagnosis. The consideration of protocol layers, data routing, and energy optimization strategies improves the efficiency of healthcare delivery. Hence, this work presents some key contributions. Firstly, it proposes a novel avant-garde framework to simultaneously optimize the energy efficiency, battery lifetime, and reliability for smart and connected healthcare. Secondly, in this study, an Adaptive Transmission Data Rate (ATDR) mechanism is proposed, which works on the average constant energy consumption by varying the active time of the sensor node to optimize the energy over the dynamic wireless channel. Moreover, a Self-Adaptive Routing Algorithm (SARA) is developed to adopt a dynamic source routing mechanism with an energy-efficient and shortest possible path, unlike the conventional routing methods. Lastly, real-time datasets are adopted for intensive experimental setup for revealing pervasive and cost-effective healthcare through wearable devices. It is observed and analysed that proposed algorithms outperform in terms of high energy efficiency, better reliability, and longer battery lifetime of portable devices.

Anti-Disturbance Compensation-Based Nonlinear Control for a Class of MIMO Uncertain Nonlinear Systems.

Multi-Inputs-Multi-Outputs (MIMO) systems are recognized mainly in industrial applications with both input and state couplings, and uncertainties. The essential principle to deal with such difficulties is to eliminate the input couplings, then estimate the remaining issues in real-time, followed by an elimination process from the input channels. These difficulties are resolved in this research paper, where a decentralized control scheme is suggested using an Improved Active Disturbance Rejection Control (IADRC) configuration. A theoretical analysis using a state-space eigenvalue test followed by numerical simulations on a general uncertain nonlinear highly coupled MIMO system validated the effectiveness of the proposed control scheme in controlling such MIMO systems. Time-domain comparisons with the Conventional Active Disturbance Rejection Control (CADRC)-based decentralizing control scheme are also included.

Adaptive work in the primary health care response to domestic violence in occupied Palestinian territory: a qualitative evaluation using Extended Normalisation Process Theory.

BACKGROUND: A health system response to domestic violence against women is a global priority. However, little is known about how these health system interventions work in low-and-middle-income countries where there are greater structural barriers. Studies have failed to explore how context-intervention interactions affect implementation processes. Healthcare Responding to Violence and Abuse aimed to strengthen the primary healthcare response to domestic violence in occupied Palestinian territory. We explored the adaptive work that participants engaged in to negotiate contextual constraints. METHODS: The qualitative study involved 18 participants at two primary health care clinics and included five women patients, seven primary health care providers, two clinic case managers, two Ministry of Health based gender-based violence focal points and two domestic violence trainers. Semi-structured interviews were used to elicit participants' experiences of engaging with HERA, challenges encountered and how these were negotiated. Data were analysed using thematic analysis drawing on Extended Normalisation Process Theory. We collected clinic data on identification and referral of domestic violence cases and training attendance. RESULTS: HERA interacted with political, sociocultural and economic aspects of the context in Palestine. The political occupation restricted women's movement and access to support services, whilst the concomitant lack of police protection left providers and women feeling exposed to acts of family retaliation. This was interwoven with cultural values that influenced participants' choices as they negotiated normative structures that reinforce violence against women. Participants engaged in adaptive work to negotiate these challenges and ensure that implementation was safe and workable. Narratives highlight the use of subterfuge, hidden forms of agency, governing behaviours, controls over knowledge and discretionary actions. The care pathway did not work as anticipated, as most women chose not to access external support. An emergent feature of the intervention was the ability of the clinic case managers to improvise their role. CONCLUSIONS: Flexible use of ENPT helped to surface practices the providers and women patients engaged in to make HERA workable. The findings have implications for the transferability of evidenced based interventions on health system response to violence against women in diverse contexts, and how HERA can be sustained in the long-term.

Improvement method for cervical cancer detection: A comparative analysis.

Cervical cancer is a prevalent and deadly cancer that affects women all over the world. It affects about 0.5 million women anually and results in over 0.3 million fatalities. Diagnosis of this cancer was previously done manually, which could result in false positives or negatives. The researchers are still contemplating how to detect cervical cancer automatically and how to evaluate Pap smear images. Hence, this paper has reviewed several detection methods from the previous researches that has been done before. This paper reviews pre-processing, detection method framework for nucleus detection, and analysis performance of the method selected. There are four methods based on a reviewed technique from previous studies that have been running through the experimental procedure using Matlab, and the dataset used is established Herlev Dataset. The results show that the highest performance assessment metric values obtain from Method 1: Thresholding and Trace region boundaries in a binary image with the values of precision 1.0, sensitivity 98.77%, specificity 98.76%, accuracy 98.77% and PSNR 25.74% for a single type of cell. Meanwhile, the average values of precision were 0.99, sensitivity 90.71%, specificity 96.55%, accuracy 92.91% and PSNR 16.22%. The experimental results are then compared to the existing methods from previous studies. They show that the improvement method is able to detect the nucleus of the cell with higher performance assessment values. On the other hand, the majority of current approaches can be used with either a single or a large number of cervical cancer smear images. This study might persuade other researchers to recognize the value of some of the existing detection techniques and offer a strong approach for developing and implementing new solutions.