Obstructive Sleep-Disordered Breathing in Infants with Normal Awake Clinical Examination: Contribution of Drug-Induced Sleep Endoscopy.

OBJECTIVES: To determine the cause of obstructive sleep-disordered breathing using drug-induced sleep endoscopy (DISE) in infants without co-morbidities and with normal clinical examination. METHODS: This prospective study was conducted between December 2019 and June 2022 (31 mo). All infants referred for obstructive sleep-disordered breathing with normal clinical examination and flexible laryngoscopy were included and underwent DISE. The location of the obstructive sites was scored similarly according to the NAVOTEL scoring system, previously established and validated by authors' team. RESULTS: Thirty-two infants were included. DISE identified an obstructive site in 94% of cases. The mean age was 16.4 mo, and the median was 16.7 mo. The obstructive sites found were isolated sleep laryngomalacia (37.4%), adenotonsillar hypertrophy (21.8%), isolated adenoidal hypertrophy (6.3%), adenotonsillar hypertrophy associated with sleep laryngomalacia (6.3%), circumferential upper airway narrowing (6.3%), glossoptosis (6.3%), isolated inferior turbinate hypertrophy (3.1%), adenoidal and tongue base hypertrophy (3.1%), and adenoidal hypertrophy with sleep laryngomalacia (3.1%). No obstructive causes could be found in 2 cases (6.3%). DISE identified an obstructive site in 30/32 patients (93.8%) and guided the surgical management in 26/32 cases (81.3%) during the same general anesthesia. The infants without surgical obstacles were referred for medical treatment. CONCLUSIONS: DISE is an excellent diagnostic and pre-therapeutic tool in infants with no apparent cause at the awake examination to identify the obstructive sites and guide the treatment.

Drug-Induced sleep endoscopy in children: NAVOTEL scoring system development.

OBJECTIVES: Pediatric drug-induced sleep endoscopy (DISE) lacks a universal and easy-to-use scoring system. The velum, oropharynx, tongue, epiglottis (VOTE) scoring system is widely used but needs to be completed in pediatrics. The main objective of this study was to investigate the distribution of obstructive sites in DISE and to propose an appropriate pediatric scoring system. The secondary objective was to evaluate the changes in surgical management induced by the proposed scoring system. METHODS: A single-center prospective 5-year study was conducted from March 2016 to December 2021, including 99 children with a mean age of 7.2 years (±3.7), with pathological preoperative sleep recordings and undergoing DISE. The distribution of all upper airway obstructive sites was studied. RESULTS: Adenoids (A) were the most frequent obstructive site (63% of patients), and the nasal cavities (N) and the larynx (L) were other frequent obstructive sites. These sites are not explored by the VOTE scoring system, leading to the creation of the nose, adenoids, velum, oropharynx, tongue, epiglottis, larynx (NAVOTEL) scoring system. NAVOTEL was significantly correlated with the severity of obstructive sleep apnea-hypopnea syndrome (OSAS) (ρ = 0.2; p = 0.04) and highlighted obstructive sites in 6/9 patients with VOTE = 0. Of these patients, 4 had a complete obstructive site, and 3 had a multisite obstruction. VOTE indicated 8 additional surgical actions; NAVOTEL indicated 50 other actions compared to clinical examination. The NAVOTEL scoring system was exhaustive regarding surgical indications for OSAS. CONCLUSIONS: The NAVOTEL scoring system is exhaustive in pediatric DISE and correlated to OSAS severity. It should be preferred in pediatric DISE.

[Conductive hearing loss with a normal eardrum]. / Surdité de transmission à tympan normal.

Conductive hearing loss with a normal eardrum. Conductive hearing loss with a normal eardrum is defined by a hearing loss in in relation to a disturbance in the transmission of sound waves from a normal eardrum to an intact cochlear nerve. The interest in diagnosing these kinds of hearing loss is due on the one hand to their high frequency, on the other hand to the socio-professional repercussions that they can induce and finally to the fact that a large part of them are accessible to surgical treatment or, hearing aid. The CT-scan contributes to the diagnostic orientation and the preoperative assessment. If the pathologies of the middle ear dominate in frequency the possible causes of conductive hearing loss with a normal eardrum, especially otosclerosis, abnormalities of the inner ear, which can be responsible for conductive or mixed hearing loss, have recently listed thanks to advances in modern digital imaging. After a brief anatomical reminder of the tympano-ossicular system, we will deal with their positive, differential and etiological diagnosis.

Surdité de transmission à tympan normal. Les surdités de transmission à tympan normal sont définies par une diminution de la capacité auditive en relation avec une perturbation de transmission de l'onde sonore depuis un tympan normal jusqu'à un nerf cochléaire intègre. L'intérêt de diagnostiquer ces surdités tient d'une part à leur grande fréquence, d'autre part au retentissement socioprofessionnel qu'elles peuvent induire, et enfin au fait qu'une grande partie d'entre elles sont accessibles à un traitement chirurgical, ou à défaut prothétique. La tomodensitométrie contribue à l'orientation diagnostique et au bilan préopératoire. Si les pathologies de l'oreille moyenne dominent en fréquence les causes possibles de surdité de transmission à tympan normal, avec en tête l'otospongiose, des anomalies de l'oreille interne, pouvant être responsables de surdité de transmission ou de surdité mixte, ont été récemment répertoriées grâce aux progrès de l'imagerie numérique moderne.