[Incidental diagnosis of medullary thyroid carcinoma (MTC) after performing 123I-metaiodobenzylguanidine (123I-MIBG) gammagraphy]. / Diagnóstico de carcinoma medular de tiroides (CMT) de forma casual tras realización de gammagrafía 123I-metayodobencilguanidina (123I-MIBG).

UNLABELLED: The objective of this clinical note is to emphasize diagnostic efficiency of 123I-MIBG scintigraphy in the initial diagnosis and follow-up of medullary thyroid carcinoma within MEN2. MATERIALS AND METHODS: We present the case of a patient who, during a scintigraphic study with 123I-MIBG for the diagnosis of pheochromocytoma, was unexpectedly found to suffer from medullary carcinoma of the thyroid. Prior to performing the test, we proceeded to block uptake into the thyroid gland through the administration of Lugol. We carried out the scintigraphic study by intravenously injecting 370 MBq 123I-MIBG. RESULTS: A pathological uptake of the radiopharmaceutical compound over the right suprarenal gland, and unexpectedly, over the thyroid gland was detected, thus confirming the existence of medullary carcinoma of the thyroid in this patient, and obtaining the diagnosis of Type MEN2A polyglandular syndrome. CONCLUSIONS: From our experience, we can manifest the value of scintigraphy using 123I-MIBG in the diagnosis and localization of medullary carcinoma of the thyroid. Furthermore, it is indicated in patients suspected of MEN, since it makes it possible to reach a diagnosis of this kind of syndrome through the performance of just one test.

[Clinical and endocrinological aspects of delusional depression]. / Aspectos clínicos y neuroendocrinológicos de las depresiones delirantes.

A comparative study of 26 delusional depressive patients versus 47 non-delusional depressed controls is presented. In addition to the clinical evaluation, the dexamethasone suppression test was performed. The results show higher severity and increased retardation in the delusional sample. The breakdown of delusions demonstrates that the most common delusions were of reference and guilt. Multiple delusions were found more frequently than one type of delusions. The D.S.T. results show no significant differences between the rates of abnormal responses in both groups. However in the delusional depressive sample with mood-incongruency there was a higher percentage of normal responses.

Aspectos clinicos y neuroendocrinologicos de las depresiones delirantes. / Clinical and endocrinological aspects of delusional depression

Se describen los datos obtenidos en un analisis comparativo de 26 pacientes con depresion delirante y 47 controles con depresion simple. Ademas de la evaluacion clinica se procedio a la aplicacion del test de supresion de la dexametasona. Los resultados del estudio en la muestra delirante muestran una edad media mas avanzada asi como una mayor gravedad de la sintomatologia y un predominio de la inhibicion. El analisis del contenido delirante indica que los delirios mas comunes son los de culpa y paranoide, constatandose en la mayoria de los casos mas de un tipo de delirio. Los resultados del test de supresion de la dexametasona no arrojan diferencias significativas entre los porcentajes de respuestas anormales correspondientes a ambas muestras. Sin embargo, en el subgrupo de depresiones delirantes con incongruencia del animo se ha encontrado un mayor porcentaje de respuestas normales

Aspectos clínicos y neuroendocrinológicos de las depresiones delirantes. / [Clinical and endocrinological aspects of delusional depression]

A comparative study of 26 delusional depressive patients versus 47 non-delusional depressed controls is presented. In addition to the clinical evaluation, the dexamethasone suppression test was performed. The results show higher severity and increased retardation in the delusional sample. The breakdown of delusions demonstrates that the most common delusions were of reference and guilt. Multiple delusions were found more frequently than one type of delusions. The D.S.T. results show no significant differences between the rates of abnormal responses in both groups. However in the delusional depressive sample with mood-incongruency there was a higher percentage of normal responses.

Aspectos clinicos y neuroendocrinologicos de las depresiones delirantes. / Clinical and endocrinological aspects of delusional depression

Se describen los datos obtenidos en un analisis comparativo de 26 pacientes con depresion delirante y 47 controles con depresion simple. Ademas de la evaluacion clinica se procedio a la aplicacion del test de supresion de la dexametasona. Los resultados del estudio en la muestra delirante muestran una edad media mas avanzada asi como una mayor gravedad de la sintomatologia y un predominio de la inhibicion. El analisis del contenido delirante indica que los delirios mas comunes son los de culpa y paranoide, constatandose en la mayoria de los casos mas de un tipo de delirio. Los resultados del test de supresion de la dexametasona no arrojan diferencias significativas entre los porcentajes de respuestas anormales correspondientes a ambas muestras. Sin embargo, en el subgrupo de depresiones delirantes con incongruencia del animo se ha encontrado un mayor porcentaje de respuestas normales