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1.
BMJ Case Rep ; 16(9)2023 Sep 29.
Artículo en Inglés | MEDLINE | ID: mdl-37775279

RESUMEN

The incidence of sebaceous carcinoma (SC) in the outer one-third of the external auditory canal is considered extremely rare, and only eight case reports have been published. We present a case of a male patient in his late 70s known case of hypertension on indapamide. His medical history included a postspinal tumour that had been treated with surgery and radiation more than 40 years ago and current complaints of right ear pain and purulent discharge. A right ear soft granular tissue mass was found. Complete debulking of the right ear mass was done in conjunction with middle ear exploration, moderately differentiated SC diagnosis was made based on the histopathological analysis. The patient was free of recurrence but then died of an unrelated pulmonary infection. SC should be suspected in elderly patients who present with long-term complaints of a mass with or without otalgia, and these patients should be examined for the presence of such tumours especially if they report a history of radiation. Additionally, more research is warranted to investigate the association of diuretics with SC.


Asunto(s)
Carcinoma , Enfermedades del Oído , Neoplasias del Oído , Humanos , Masculino , Anciano , Conducto Auditivo Externo/patología , Enfermedades del Oído/patología , Oído Medio/patología , Dolor de Oído , Carcinoma/patología , Neoplasias del Oído/diagnóstico , Neoplasias del Oído/cirugía , Neoplasias del Oído/patología
2.
J Pharm Bioallied Sci ; 13(Suppl 2): S1728-S1732, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35018064

RESUMEN

Olfactory neuroblastoma (ONB) or esthesioneuroblastoma is a rare malignancy of the nose and paranasal sinuses that originates from the upper nasal vault. We report a rare case of ONB in a 27-year-old female patient with a 2-year history of nasal obstruction, sneezing, nasal discharge, and left eye protrusion. The patient was successfully treated with endoscopic sinus surgery and adjuvant radiotherapy (RT) with 5-year follow-up duration. Studying ONB cases is of great importance due to its rare occurrence, and the lack of literature regarding its management often creates a dilemma leading to nonstandardized treatment methods. Prolonged surveillance is essential due to its late recurrence and endoscopic resection followed by adjuvant RT, which may be a feasible and effective treatment. There is no single case of ONB published yet in Saudi Arabia, and to our knowledge, this is the first case report.

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