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1.
J Clin Virol Plus ; 2(1): 100065, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-35262036

RESUMEN

In the context of SARS-CoV-2 pandemic, rapid and easy-to-perform diagnostic methods are essential to limit the spread of the virus and for the clinical management of COVID-19 patients. Although real-time polymerase chain reaction remains the "gold standard" to diagnose acute infections, this technique is expensive, requires trained personnel, well-equipped laboratory and is time-consuming. A prospective evaluation of the Abbott ID NOW COVID-19 point-of-care testing that uses isothermal nucleic acid amplification for the qualitative detection of SARS-CoV-2 RdRp gene was run in the Emergency Department during the third wave of COVID-19 pandemic. ID-NOW significantly simplified SARS-CoV-2 identification and COVID-19 patient triaging, being highly valuable in rapidly locating febrile patients in or out of COVID-19 areas, and can be considered as a first-line diagnostic test in the Emergency Room setting.

2.
Ann Noninvasive Electrocardiol ; 23(5): e12535, 2018 09.
Artículo en Inglés | MEDLINE | ID: mdl-29488680

RESUMEN

Yew leaves poisoning is a rare life-threatening intoxication, whose diagnosis can be difficult. Initial symptoms are nausea, vomiting, abdominal pain, dizziness, tachycardia, muscle weakness, confusion, beginning within 1 hr from ingestion and followed by bradycardia, ventricular arrhythmias, ventricular fibrillation, severe hypotension, and death. Taxine-derived alkaloids are responsible for the toxicity of the yew leaves, blocking sodium and calcium channels, and causing conduction abnormalities. Because of lack of a specific antidote and limited efficacy of common antiarrhythmic drugs, prompt diagnosis, detoxification measures, and immediate hemodynamic support (also with transvenous cardiac stimulation) are essential.


Asunto(s)
Arritmias Cardíacas/inducido químicamente , Cephalotaxus/envenenamiento , Electrocardiografía/métodos , Paro Cardíaco/inducido químicamente , Extractos Vegetales/envenenamiento , Hojas de la Planta/envenenamiento , Agonistas alfa-Adrenérgicos/uso terapéutico , Adulto , Anciano , Amiodarona/uso terapéutico , Antiarrítmicos/uso terapéutico , Arritmias Cardíacas/terapia , Reanimación Cardiopulmonar , Carbón Orgánico/uso terapéutico , Femenino , Lavado Gástrico , Paro Cardíaco/terapia , Humanos , Sulfato de Magnesio/uso terapéutico , Masculino , Persona de Mediana Edad , Norepinefrina/uso terapéutico , Marcapaso Artificial , Bicarbonato de Sodio/uso terapéutico , Resultado del Tratamiento
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