1.
Acta Crystallogr F Struct Biol Commun
; 77(Pt 10): 328-333, 2021 Oct 01.
Artículo
en Inglés
| MEDLINE
| ID: mdl-34605436
RESUMEN
The 1.5â Å resolution crystal structure of DynU16, a protein identified in the dynemicin-biosynthetic gene cluster, is reported. The structure adopts a di-domain helix-grip fold with a uniquely positioned open cavity connecting the domains. The elongated dimensions of the cavity appear to be compatible with the geometry of a linear polyene, suggesting the involvement of DynU16 in the upstream steps of dynemicin biosynthesis.