Paternidade e microcefalia por Zika Vírus: sentimentos e percepções / Paternity and microcephaly by Zika Virus: feelings and perceptions

Objetivo: descrever sentimentos e percepções de pais de crianças com microcefalia por Zika vírus. Método: trata-se de estudo qualitativo, descritivo realizado com pais de filhos microcefálicos. Obtiveram-se os dados por meio de entrevista semiestruturada, analisando-os por meio da técnica do Discurso do Sujeito Coletivo. Resultados: emergiram-se, por meio da análise dos dados, quatro discursos do sujeito coletivo, a saber: Sentimentos frente ao diagnóstico de microcefalia; Estratégia de enfrentamento frente à malformação congênita do filho; Conhecimento frente às limitações do filho; Entendimento acerca do acompanhamento psicossocial. Conclusão: concluiu-se, com base nos discursos, que os sentimentos, frente ao diagnóstico de microcefalia de um filho, provocam um intenso estado de desorientação, fragilidade e preocupação referente à sobrecarga de cuidados que os pais terão com os filhos. Observou-se que a religiosidade era a principal estratégia de enfrentamento adotada pelos pais, e, com relação ao conhecimento frente às limitações dos filhos, o discurso revelou que os pais possuíam alguma informação sobre a deficiência e as limitações advindas da microcefalia. Percebeu-se, quanto ao entendimento acerca do acompanhamento psicossocial, por meio do discurso, a importância do suporte emocional.(AU)

Objective: to describe the feelings and perceptions of parents of children with microcephaly by Zika virus. Method: this is a qualitative, descriptive study performed with parents of microcephalic children. The data were obtained through a semi-structured interview, analyzing them through the technique of the Discourse of the Collective Subject. Results: four discourses of the collective subject emerged through the analysis of the data, namely: Feelings before the diagnosis of microcephaly; A coping strategy for congenital malformation of the child; Knowledge regarding the limitations of the child; Understanding about psychosocial monitoring. Conclusion: it was concluded from the discourses that the feelings, given the diagnosis of a child's microcephaly, provoke an intense state of disorientation, fragility and concern regarding the overload of care that parents will have with their children. It was observed that religiosity was the main coping strategy adopted by the parents and, in relation to the knowledge about the limitations of the children, the discourse revealed that the parents had some information about the deficiency and limitations of microcephaly. The importance of emotional support was understood through the discourse about psychosocial accompaniment.(AU)

Objetivo: describir sentimientos y percepciones de padres de niños con microcefalia por Zika virus. Método: se trata de un estudio cualitativo, descriptivo realizado con padres de hijos microcefálicos. Se obtuvieron los datos por medio de entrevista semiestructurada, analizándolos por medio de la técnica del Discurso del Sujeto Colectivo. Resultados: surgieron, por medio del análisis de los datos, cuatro discursos del sujeto colectivo, a saber: Sentimientos frente al diagnóstico de microcefalia; Estrategia de enfrentamiento frente a la malformación congénita del hijo; Conocimiento frente a las limitaciones del hijo; Entendimiento sobre el acompañamiento psicosocial. Conclusión: se concluyó, con base en los discursos, que los sentimientos, frente al diagnóstico de microcefalia de un hijo, provocan un intenso estado de desorientación, fragilidad y preocupación referente a la sobrecarga de cuidados que los padres tendrán con los hijos. Se observó que la religiosidad era la principal estrategia de enfrentamiento adoptada por los padres, y, con relación al conocimiento frente a las limitaciones de los hijos, el discurso reveló que los padres poseían alguna información sobre la deficiencia y las limitaciones provenientes de la microcefalia. Se percibió, en cuanto al entendimiento acerca del acompañamiento psicosocial, por medio del discurso, la importancia del soporte emocional.(AU)

Echocardiographic abnormalities and antiphospholipid antibodies in patients with systemic lupus erythematosus.

OBJECTIVE: Lupus anticoagulant and anticardiolipin antibodies (aCL) have been associated with thrombosis, recurrent abortion, and thrombocytopenia in patients with systemic lupus erythematosus (SLE), but their relationship with cardiac disease is less clear. The purpose of this study was to evaluate the association between antiphospholipid antibodies (aPL) and echocardiographic abnormalities in patients with SLE. METHODS: A total of 70 consecutive patients and 42 control subjects underwent M-mode, 2-dimensional and Doppler echocardiography and tests for lupus anticoagulant, aCL IgG, IgM, and IgA. Lupus anticoagulant was assayed with the dilute Russell viper venom time, and aCL IgG, IgM, and IgA were measured by an enzyme-linked immunosorbent assay (ELISA). RESULTS: Lupus anticoagulant showed a prevalence of 10%. As a whole, aCL had a prevalence of 44.3% and aPL had a prevalence of 50%. Patients with echocardiographic abnormalities had a prevalence of 54.3% and showed a trend towards an association with aCL IgG (P=0.06). The presence of pulmonary hypertension (PH) was significantly associated with aCL IgG (p=0.02). CONCLUSION: aCL IgG was significantly associated with PH and showed a strong trend towards an association with echocardiographic abnormalities taken together. These findings suggest a role for aCL IgG in the development of lupus cardiovascular disease.

Echocardiographic abnormalities and antiphospholipid antibodies in patients with systemic lupus erythematosus

OBJECTIVE: Lupus anticoagulant and anticardiolipin antibodies (aCL) have been associated with thrombosis, recurrent abortion, and thrombocytopenia in patients with systemic lupus erythematosus (SLE), but their relationship with cardiac disease is less clear. The purpose of this study was to evaluate the association between antiphospholipid antibodies (aPL) and echocardiographic abnormalities in patients with SLE. METHODS: A total of 70 consecutive patients and 42 control subjects underwent M-mode, 2-dimensional and Doppler echocardiography and tests for lupus anticoagulant, aCL IgG, IgM, and IgA. Lupus anticoagulant was assayed with the dilute Russell viper venom time, and aCL IgG, IgM, and IgA were measured by an enzyme-linked immunosorbent assay (ELISA). RESULTS: Lupus anticoagulant showed a prevalence of 10 percent. As a whole, aCL had a prevalence of 44.3 percent and aPL had a prevalence of 50 percent. Patients with echocardiographic abnormalities had a prevalence of 54.3 percent and showed a trend towards an association with aCL IgG (P=0.06). The presence of pulmonary hypertension (PH) was significantly associated with aCL IgG (p=0.02). CONCLUSION: aCL IgG was significantly associated with PH and showed a strong trend towards an association with echocardiographic abnormalities taken together. These findings suggest a role for aCL IgG in the development of lupus cardiovascular disease