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1.
Nutr Metab Cardiovasc Dis ; 22(6): 533-9, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21543197

RESUMEN

BACKGROUND AND AIMS: Although studies have shown association of birth weight (BW) and adult body mass index (BMI) with insulin sensitivity in adults, there is limited evidence that BW is associated with insulin secretion. We assessed the associations between BW and current BMI with insulin sensitivity and secretion in young Latin American adults. METHODS AND RESULTS: Two birth cohorts, one from Ribeirao Preto, Brazil, based on 1984 participants aged 23-25 years, and another from Limache, Chile, based on 965 participants aged 22-28 years were studied. Weight and height at birth, and current fasting plasma glucose and insulin levels were measured. Insulin sensitivity (HOMA%S) and secretion (HOMA%ß) were estimated using the Homeostatic Model Assessment (HOMA2). Multiple linear regression analyses were carried out to test the associations between BW and adult BMI z-scores on log HOMA%S and log HOMA%ß. BW z-score was associated with HOMA%S in the two populations and HOMA%ß in Ribeirao Preto when adult BMI z-score was included in the model. BW z-score was associated with decreasing insulin secretion even without adjusting for adult BMI, but only in Ribeirao Preto. BMI z-score was associated with low HOMA%S and high HOMA%ß. No interactions between BW and BMI z-scores on insulin sensitivity were shown. CONCLUSIONS: This study supports the finding that BW may affect insulin sensitivity and secretion in young adults. The effect size of BW on insulin status is small in comparison to current BMI.


Asunto(s)
Peso al Nacer , Composición Corporal , Índice de Masa Corporal , Resistencia a la Insulina , Insulina/sangre , Insulina/metabolismo , Adulto , Glucemia/análisis , Brasil/epidemiología , Chile/epidemiología , Estudios de Cohortes , Ayuno , Femenino , Estudios de Seguimiento , Humanos , Secreción de Insulina , América Latina/epidemiología , Masculino , Encuestas y Cuestionarios , Adulto Joven
2.
Am J Hum Biol ; 22(5): 688-94, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20737618

RESUMEN

OBJECTIVES: To estimate the secular trend in age at menarche, comparing indigenous and nonindigenous women, and its relationship with socio-demographic, family and nutritional factors. METHODS: A study (historical cohorts) of 688 indigenous and nonindigenous women, divided into four birth cohorts (1960-69, 1970-79, 1980-89, and 1990-96) in an area in central southern Chile was carried out. Data and measurements were collected by health professionals using a previously validated questionnaire. Age at menarche was self-reported (recall). Adjusted differences among cohorts were estimated using a multivariate regression model. RESULTS: A secular trend (P < 0.001) in age at menarche was found in both ethnic groups, with no significant differences between them (P > 0.05). In an adjusted model, a reduction in age at menarche was estimated at 3.7 months per decade between 1960 and 1990. This trend was moderated by higher socio-economic level, smaller number of siblings, and cohabitation with a single parent during infancy. CONCLUSIONS: The trend has occurred in a steady progression over time in indigenous women, whereas in nonindigenous women, it was slow initially but has accelerated in recent years. Nonindigenous women have maintained a slightly lower age of menarche than their indigenous counterparts.


Asunto(s)
Composición Familiar/etnología , Menarquia/etnología , Estado Nutricional/etnología , Adolescente , Distribución por Edad , Niño , Chile , Estudios de Cohortes , Recolección de Datos , Femenino , Humanos , Modelos Logísticos , Factores Socioeconómicos , Encuestas y Cuestionarios
3.
Clin Exp Allergy ; 39(3): 379-86, 2009 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-19187326

RESUMEN

BACKGROUND AND AIM: Enhanced oxidative stress has been described in adults who suffer from symptoms of asthma and poor lung function. This study assessed the relation between markers of oxidative stress and antioxidant status and lung function, symptoms of asthma, atopy and bronchial hyperresponsiveness (BHR) in young adults. METHODS: A sub-sample of 589 individuals aged 22-28 years, selected from a total of 1232 included in a survey assessing early and current risk factors for chronic diseases, participated in the study. Participants were from an agricultural area of Chile, responded to a Spanish version of the European Community Respiratory Health Survey questionnaire, were skin tested to eight allergens, and challenged with methacholine to assess BHR. Five hundred and eighty-five individuals had measures of plasma biomarkers ferric reducing ability of plasma, uric acid, protein carbonyls and 564 had 8-iso-prostaglandin F(2alpha) (8-iso-PGF(2alpha)) assessed. RESULTS: All participants had detectable plasma 8-iso-PGF(2alpha) and carbonyl levels. There was no indication for an association between markers of antioxidant status or oxidative stress with any of the outcomes studied. CONCLUSION: The levels of oxidative stress-related biomarkers and antioxidant status in plasma may not be related to asthma in the general population in the absence of more severe symptoms or exacerbations.


Asunto(s)
Antioxidantes/metabolismo , Asma/sangre , Biomarcadores/sangre , Hipersensibilidad/sangre , Estrés Oxidativo , Adulto , Alérgenos/inmunología , Asma/epidemiología , Asma/fisiopatología , Proteínas Sanguíneas/análisis , Proteínas Sanguíneas/metabolismo , Índice de Masa Corporal , Dinoprost/análogos & derivados , Dinoprost/sangre , Femenino , Compuestos Férricos/química , Volumen Espiratorio Forzado/fisiología , Humanos , Hipersensibilidad/epidemiología , Hipersensibilidad/inmunología , Masculino , Oxidación-Reducción , Carbonilación Proteica , Pruebas de Función Respiratoria , Ruidos Respiratorios/diagnóstico , Ácido Úrico/sangre , Capacidad Vital/fisiología , Adulto Joven
4.
Clin Exp Allergy ; 38(11): 1778-86, 2008 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-18644022

RESUMEN

BACKGROUND: The pattern of associations and the attributable fractions (AF) of atopic conditions due to specific sensitizations vary between countries. OBJECTIVE: To assess the level of associations and AF between sensitization to five allergens and atopic conditions in two settings. METHODS: We studied 2063 Brazilians and 1231 Chileans of both sexes using representative samples selected at birth in the 1970s. Information on asthma and rhinitis was based on the European Community Respiratory Health Survey questionnaire. We assessed bronchial hyperresponsiveness (BHR) to methacholine and sensitization to Dermatophagoides pteronyssinus, cat, dog, grass blend and Alternaria alternata. RESULTS: The prevalence of sensitization to one or more allergens was 50% in Brazilians and 22% in Chileans. The level of associations varied according to the outcome used. Strong associations between sensitization and asthma, defined as wheeze or awakening with breathlessness at night and positive BHR, were found for each of the five allergens in Chileans [varying from odds ratio (OR) 3.24, 95% confidence interval (CI) 1.47, 7.15 for D. pteronyssinus to 8.44, 95% CI 3.82, 18.66 for cat], whereas the level of associations was restricted to D. pteronyssinus, cat and dog in Brazilians and was somewhat weaker (highest OR 3.90, 95% CI 2.80-5.44). The AF of sensitization on asthma was 54% in Brazil and 44% in Chile. D. pteronyssinus and cat made an independent contribution to asthma in the two samples. The patterns of associations between sensitization and rhino-conjunctivitis were similar to those for asthma. CONCLUSION: The associations between sensitization, and asthma and rhinitis were high in Chile and moderately high in Brazil, but the AF were higher in Brazil, reflecting a higher prevalence of sensitization. In Brazil, dust mite had the greatest impact on atopic conditions while in Chile several allergens had an impact. Sensitization is as serious a problem in Chile and Brazil as in developed countries.


Asunto(s)
Asma/etiología , Hipersensibilidad Inmediata/complicaciones , Hipersensibilidad Inmediata/inmunología , Rinitis Alérgica Perenne/etiología , Rinitis Alérgica Estacional/etiología , Adulto , Alérgenos/inmunología , Alternaria/inmunología , Animales , Animales Domésticos/inmunología , Antígenos Dermatofagoides/inmunología , Antígenos de Plantas/inmunología , Asma/epidemiología , Brasil , Hiperreactividad Bronquial/epidemiología , Hiperreactividad Bronquial/etiología , Pruebas de Provocación Bronquial , Gatos , Chile , Conjuntivitis Alérgica/epidemiología , Conjuntivitis Alérgica/etiología , Estudios Transversales , Perros , Femenino , Humanos , Hipersensibilidad Inmediata/epidemiología , Masculino , Ruidos Respiratorios/etiología , Rinitis Alérgica Perenne/epidemiología , Rinitis Alérgica Estacional/epidemiología , Pruebas Cutáneas , Adulto Joven
5.
Ann Hum Biol ; 35(3): 322-33, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-18568595

RESUMEN

OBJECTIVE: The study assessed the impact of body mass index (BMI) at birth, infancy, and adulthood, and waist circumference on lung function. METHODS: Using a longitudinal design 1221 Chilean young adults were studied. A standardized respiratory questionnaire was used. Forced expiratory volume in 1 s (FEV(1)), forced vital capacity (FVC), height, weight and waist circumference were measured. Data at birth and at 1 year were obtained from clinical notes. RESULTS: Males with a BMI > or = 30 and women with a BMI < 20 had a lower FEV(1) (-230 mL, 95% CI -363 to -98; -106 mL, 95% CI -211 to -0.18, respectively). In both sexes those with a BMI 20-25 had the highest FEV(1) and FVC. In males there was a negative association between waist circumference and FEV(1) and FVC while in women the middle tertile had the highest FEV(1) and FVC. There was an association between birthweight and BMI at birth, and FEV(1) in men, when unadjusted for other measurements. CONCLUSIONS: BMI and waist circumference in adulthood make a greater impact on lung function in adulthood than anthropometric measurements at birth and infancy. Proxy measures of fatness in adulthood reduce lung function, but the pattern between fatness and lung function by sex may be different.


Asunto(s)
Índice de Masa Corporal , Pulmón/fisiología , Pulmón/fisiopatología , Estado Nutricional , Grasa Abdominal , Adulto , Factores de Edad , Estatura , Femenino , Edad Gestacional , Humanos , Estudios Longitudinales , Masculino , Flujo Espiratorio Medio Máximo/fisiología , Estado Nutricional/fisiología , Sobrepeso/complicaciones , Embarazo , Trastornos Respiratorios/etiología , Trastornos Respiratorios/fisiopatología , Espirometría , Delgadez , Capacidad Vital/fisiología , Relación Cintura-Cadera/efectos adversos
7.
Int J Tuberc Lung Dis ; 10(7): 744-9, 2006 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-16848335

RESUMEN

OBJECTIVE: To assess the association between smoking and respiratory symptoms, lung function and bronchial hyperresponsiveness (BHR) in young adults in Chile. SETTING: Selected sample of 1232 subjects aged 22-28 years. DESIGN: In this cross-sectional study, the outcome measures were: respiratory symptoms, forced expiratory volume in one second (FEV1), forced vital capacity (FVC), forced expiratory flow between 25% and 75% (FEF25-75), FEV1/FVC and BHR. RESULTS: Among the 1232 subjects, 67.7% of the men and 49.4% of the women were smokers; the median cigarettes smoked per day was four for men and three for women. Smoking was associated with wheezing, waking up with a cough, breathlessness following exercise and persistent cough, with odds ratios (OR) between 1.94 (95% CI 1.41-2.66) and 3.12 (95% CI 2.21-4.40) among those smoking > or = 5 cigarettes per day, compared to non-smokers. Smoking < 5 cigarettes was significantly associated with wheezing and waking up with a cough. Smokers had a lower FEV1/FVC than non-smokers by approximately 0.8%. Smoking was not associated with FEV1, FEF25-75 or BHR status. CONCLUSIONS: This study highlights the early effects of smoking on respiratory symptoms. It could help governments in Latin America take vigorous action to deter young people from starting smoking.


Asunto(s)
Pruebas de Función Respiratoria , Fumar/fisiopatología , Adulto , Chile , Estudios Transversales , Femenino , Humanos , Masculino
8.
Int J Tuberc Lung Dis ; 9(11): 1288-93, 2005 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-16333939

RESUMEN

OBJECTIVE: To assess the prevalence of asthma symptoms and their association with sensitisation to eight allergens and bronchial hyperresponsiveness (BHR) to methacholine. SETTING: A random sample of 1232 adults, aged 22 to 28 years, studied in a Chilean semi-rural area. DESIGN: A cross-sectional design for the purpose of this analysis. RESULTS: The prevalence of wheeze was 27.4% (95%CI 24.9-29.9) and waking with breathlessness 13.7% (95%CI 11.8-15.6), higher than the results of a multi-centre European study. Only 7.8% (95%CI 6.3-9.3) had a positive BHR (< or =8 mg/ml) and 26.3% (95%CI 23.8-28.8) were atopic. The Youden index of asthma symptoms in non-atopic subjects varied from 0.184 to 0.259 when using BHR as gold standard for asthma, and increased from 0.379 to 0.504 among those with positive atopy. Only 4.5% reported asthma, and the Youden index was slightly higher in comparison to the asthma symptom groups. CONCLUSION: The prevalence of asthma symptoms in young adults was high, but only a small proportion of these were sensitised or had a positive BHR. We believe that aetiological studies of asthma should analyse subjects with asthma symptoms separately from those with positive atopic status or positive BHR.


Asunto(s)
Asma/epidemiología , Hiperreactividad Bronquial/epidemiología , Hipersensibilidad Inmediata/epidemiología , Adulto , Chile/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Prevalencia , Salud Rural
9.
Thorax ; 60(7): 549-54, 2005 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15994261

RESUMEN

BACKGROUND: There is uncertainty about the impact of the programming hypothesis in terms of nutritional status at birth, rate of growth in the first year of life, length of gestation, breast feeding, and episodes of illness on asthma. An analysis was therefore carried out to test this hypothesis. METHODS: Data were collected on 1232 children born between 1974 and 1978 in a semi-rural area of Chile. Measurements at birth and growth in the first year of life were obtained from a birth registry and clinical notes. Information on asthma was collected using the European Community Respiratory Health Survey questionnaire. Sensitisation to eight allergens and bronchial hyperresponsiveness (BHR) to methacholine were determined. All other information was obtained using a questionnaire. Polytomous logistic analyses were carried out to explore the association of factors at birth and during the first year of life with asthma symptoms, atopy, and BHR. RESULTS: Weight and length gain in the first year were positively associated with wheeze (odds ratio (OR) 1.004, 95% CI 1.001 to 1.007 and OR 1.11, 95% CI 0.98 to 1.25, respectively). A higher body mass index (BMI) at birth was protective in subjects reporting both wheeze and waking with breathlessness (OR 0.54, 95% CI 0.35 to 0.84). Length rate in tertiles divided by length at birth in tertiles was related to asthma symptoms (OR 1.68, 95% CI 1.19 to 2.37). Most other assessments were not associated with asthma. CONCLUSION: These results show promising but inconclusive evidence that a rapid rate of growth in length, especially in newborn infants of low length, might be involved in the aetiology of asthma.


Asunto(s)
Asma/fisiopatología , Crecimiento , Asma/epidemiología , Estatura/fisiología , Índice de Masa Corporal , Chile/epidemiología , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Oportunidad Relativa , Estudios Prospectivos , Salud Rural
10.
Int J Obes (Lond) ; 29(7): 804-9, 2005 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15824747

RESUMEN

OBJECTIVE: An association between obesity and asthma symptoms has been reported in the literature, but such a relationship is inconsistent if atopic status or bronchial hyper responsiveness (BHR) is considered. The objective was to assess the association between obesity and asthma symptoms or BHR in adults. METHODS: A study was carried out in 1232 people born between 1974 and 1978 in Chile. The participants completed the European Community Health Survey questionnaire, were skin tested and subject to a BHR challenge to methacholine. MEASUREMENTS: Weight, height and waist circumference were measured and body mass index (BMI) was calculated. RESULTS: There was a positive association between wheeze and breathlessness following exercise and BMI (both with an OR 1.03, 95% CI 1.00-1.06), the associations with wheeze tended to disappear in women who did react at least to one allergen, and persisted in those who did not react to any allergens. BMI was negatively associated with BHR (OR 0.93, 95% CI 0.89-0.97). Waist circumference was not associated with asthma symptoms and it was negatively associated with BHR. CONCLUSION: Although there was an association between BMI and asthma symptoms, there were weaknesses in the evidence because waist circumference, a more direct measure of obesity than BMI, was not associated with asthma symptoms, and BMI and waist circumference were negatively associated with BHR.


Asunto(s)
Asma/etiología , Obesidad/complicaciones , Adulto , Asma/inmunología , Hiperreactividad Bronquial , Causalidad , Chile , Estudios Transversales , Prueba de Esfuerzo , Femenino , Humanos , Modelos Logísticos , Masculino , Obesidad/inmunología
11.
Rev. méd. Chile ; 131(9): 973-980, sept. 2003.
Artículo en Español | LILACS | ID: lil-356016

RESUMEN

BACKGROUND: A precise knowledge of the prevalence and importance of cardiovascular risk factors will facilitate the development of preventive strategies. AIM: To study cardiovascular risk factors among healthy young adults. SUBJECTS AND METHODS: Eight hundred and fifty subjects aged 22 to 28 years, living in two cities in Valparaiso province, were studied. Weight, height and blood pressure were recorded. A fasting blood sample was obtained from 806 individuals (54% female), to measure plasma lipids, glucose and insulin levels, to estimate their homeostasis model assessment scores (HOMA) and to evaluate the occurrence of metabolic syndrome. RESULTS: Five percent of the studied population had high blood pressure, 14% had obesity, 57% smoked, 25% had high total cholesterol levels, 10.5% had high levels of low density lipoprotein cholesterol, 46% had low levels of high density lipoprotein cholesterol, 16% had high triglyceride levels, 36% had insulin resistance, 7% had a metabolic syndrome, 14% were heavy drinkers and 38% were sedentary. Women had a higher prevalence of obesity and metabolic syndrome. In only 24% of the studied subjects, no risk factor was identified. CONCLUSIONS: A high prevalence of cardiovascular risk factors was found in this population of young adults.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Enfermedades Cardiovasculares/etiología , Chile/epidemiología , Distribución por Sexo , Factores de Riesgo , Prevalencia , Síndrome Metabólico/epidemiología , Tabaquismo/epidemiología
12.
Arch. latinoam. nutr ; 52(4): 368-374, dic. 2002.
Artículo en Español | LILACS | ID: lil-356601

RESUMEN

The study was based on a cross-sectional design of children from six to nine year olds. Indigenous children were those whose parents had all surnames of this ethnic origin. Non-indigenous children were those with Hispanic surnames. Participants belonged to one of the three social vulnerability groups: high vulnerability (extreme poverty) living in rural communities in a southern region of the country (n = 184); medium vulnerability living in urbanized settings in the same region (n = 248); low vulnerability living in Santiago of Chile (n = 336). Food intake was estimated using a 24-hours recall questionnaire. Total energy intake was similar in the two ethnic groups in all vulnerabilities. It was observed that energy and macronutrient intake increased with the improvement of the social vulnerability: High 1679 kcal. with a standard deviation (SD) of 461, Medium 1878 (SD 484), Low 1894 (SD 495). Children in the high social vulnerability group had a total energy intake below the WHO/FAO recommendations. Consumption of milk, meat, vegetables and fruits was insufficient in all social vulnerability levels but it was closer to the recommendation in the low vulnerability group. Bread accounted for almost 50 per cent of the total energy intake in the high and medium vulnerability groups. It is concluded that differences in the access to an adequate feeding are related to social vulnerability and not ethnicity.


Asunto(s)
Humanos , Masculino , Femenino , Niño , Nutrición del Niño , Dieta , Etnicidad , Estudios Transversales , Chile/etnología , Registros de Dieta , Ingestión de Alimentos , Ingestión de Energía , Indígenas Sudamericanos , Encuestas Nutricionales , Factores Socioeconómicos
13.
Am J Public Health ; 91(10): 1645-9, 2001 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-11574328

RESUMEN

OBJECTIVES: This study sought to determine whether the short stature of Mapuche children, an indigenous group in Chile, reflects poverty or genetic heritage and whether the international reference population, derived from studies of US children of mostly European origin, is appropriate for assessing growth failure in indigenous peoples of the Americas. METHODS: The study assessed 768 schoolchildren of Mapuche and non-Mapuche ancestry, aged 6 to 9 years, living under conditions of extreme, medium, and low poverty. RESULTS: Growth retardation was strongly related to poverty in both ethnic groups. Within poverty levels, there were no significant differences in stature between ethnic groups, and in low-poverty areas in Santiago, the capital city, mean stature was only slightly less than in the reference population. CONCLUSIONS: Poverty, not ancestry, explains the short stature of Mapuche children, and use of the international reference to assess growth in this population is appropriate.


Asunto(s)
Estatura/etnología , Estatura/genética , Crecimiento/genética , Indígenas Sudamericanos , Áreas de Pobreza , Niño , Chile/epidemiología , Comparación Transcultural , Discapacidades del Desarrollo/etnología , Discapacidades del Desarrollo/etiología , Femenino , Humanos , Indígenas Sudamericanos/genética , Masculino , Prevalencia
14.
J Nutr ; 131(2): 251-4, 2001 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-11160542

RESUMEN

Stunting is highly prevalent in Latin American countries regardless of socioeconomic performance. The purpose of this study was to identify risk factors of growth deficit among children starting primary education whose parents were of short stature compared with those whose parents were not of short stature, in the poorest districts of Santiago, Chile. A case-control study was carried out with two types of cases. Case 1 included children whose height was between -1.0 and -3.0 (SD) of the height/age of the National Center for Health Statistics/World Health Organization standard and whose parent's height was below -2.0 SD (n = 115). Case 2 included stunted children (as defined previously) whose parent's height was above -2 SD (n = 76). Controls were children whose stature was +/-0.5 SD and whose parent's height was also above -2 SD (n = 115). Logistic regression models were carried out for case 1 and 2 children compared with the controls. Similar risk factors were found in both models, without any significant interaction: these included history of malnutrition, drunkenness in the family, lack of health care, unhygienic housing conditions, small length at birth and short period of exclusive breastfeeding. The most important risk factors for case 1 children were a history of malnutrition [with an odds ratio (OR) of 5.26 and confidence interval (CI) of 2.68-10.34] and short length at birth (OR = 4.87, CI 2.18-10.92). For case 2 children, the most important risk factors were a history of malnutrition (OR = 4.58, CI 2.20-9.53) and unhygienic housing conditions (OR = 4.29, CI 1.76-10.48). In conclusion, similar factors explained growth deficits in children starting primary school independent of the parent's height, suggesting that genetics would have a limited impact at this age and at this socioeconomic level. To reduce stunting in countries with an epidemiological profile such as that of Chile, it is still important to reduce adverse environmental conditions.


Asunto(s)
Estatura/fisiología , Trastornos del Crecimiento/etiología , Consumo de Bebidas Alcohólicas , Estatura/genética , Lactancia Materna , Estudios de Casos y Controles , Niño , Fenómenos Fisiológicos Nutricionales Infantiles , Chile/epidemiología , Femenino , Crecimiento , Trastornos del Crecimiento/epidemiología , Humanos , Higiene , Modelos Logísticos , Masculino , Trastornos Nutricionales , Prevalencia , Calidad de la Atención de Salud , Factores de Riesgo , Factores Socioeconómicos
15.
Arch Latinoam Nutr ; 50(2): 121-5, 2000 Jun.
Artículo en Portugués | MEDLINE | ID: mdl-11048582

RESUMEN

Aiming to analyze the mild to moderate growth retardation associate factors in children at school age, a case control study was conducted with 153 pairs of seven and eight years old children from public schools of the outskirts of the city. The cases were defined as children with a height for age(H/A) between -1 and -2 Z score, according to NCHS/WHO standards, and matched with a H/A +/- 0.5 Z-score children of same age, gender, school, classroom and class time, as controls. The height was measured at school according to WHO rules by trained professionals, and household visits were carried out to obtain environmental and socio-economic data. Initially the data was analyzed by the univariate conditional method and then, the statistically significant variables were included in a model of multivariate logistic regression analysis. As a result, the risk factors remaining at the end of the multivariate analyses, by Odds Ratio and it's 95% Confidence Interval were respectively:--mother's height: for each decrease of one standard deviation the OR increased 1.84(CI: 1.35 to 2.49); inadequate feeding pattern: OR = 2.12; CI: 1.17 to 3.83, very low socio-economic level: OR = 9.2; CI: 3.35 to 25.13, low birth weight: OR = 2.59; CI: 1.44 to 4.63 and smoking during pregnancy: OR = 1.75; CI: 0.98 to 3.12. These results highlight the environment as a determinant factor for growth performance during the first years of the child's life. Despite this, the significant OR for Mother's height allows the assumption that besides the environment, the parent's height has to be considered as one of the determinants of height deficit, even for the low socioeconomic level.


Asunto(s)
Estatura , Trastornos del Crecimiento/epidemiología , Brasil/epidemiología , Estudios de Casos y Controles , Niño , Trastornos de la Nutrición del Niño/epidemiología , Femenino , Trastornos del Crecimiento/etiología , Humanos , Modelos Logísticos , Masculino , Factores de Riesgo , Factores Socioeconómicos
16.
Salud Publica Mex ; 42(6): 504-10, 2000.
Artículo en Español | MEDLINE | ID: mdl-11201578

RESUMEN

OBJECTIVE: To analyze and compare the heights of first-year school children and their parents, according to ethnic background and socioeconomic status. MATERIAL AND METHODS: This is a cross-sectional study of indigenous and non-indigenous school children and their parents, belonging to three levels of social vulnerability: very high (poverty), medium, and very low. An indigenous school child was defined as any child having all four parental surnames of Mapuche origin; non-indigenous were those having Hispanic parental surname. Height was compared using Z scores, using WHO nutritional change reference values. Statistical analysis consisted in comparing differences of mean heights between parents and their children. Differences were assessed using Scheffe's method. RESULTS: Improvement in socioeconomic conditions was associated with increasing mean parental height (p < 0.001), except for indigenous mothers, who showed no height increase. Fathers from highly impoverished counties were 4 cm shorter than those living in very low vulnerability areas; height differences reached 2 cm among mothers (p < 0.001). Indigenous school children showed a positive height gradient with improving socioeconomic conditions (p < 0.001). This was not observed among non-indigenous children. When comparing parental height with children's height, children had a better height/age ratio than their parents (p < 0.01). This was specially evident among indigenous school children, who had on average 1.4 Z scores more than their parents. CONCLUSIONS: The upward height gradient related to improved social conditions, and the better height/age ratio seen in children in comparison to their parents, regardless their ethnic background and level of social vulnerability, is encouraging and suggests that interventions directed to the poorest groups, including the indigenous population, must be carried out.


Asunto(s)
Estatura , Adulto , Estatura/genética , Niño , Chile , Estudios Transversales , Etnicidad/genética , Femenino , Trastornos del Crecimiento/epidemiología , Trastornos del Crecimiento/etnología , Trastornos del Crecimiento/etiología , Humanos , Indígenas Sudamericanos/genética , Masculino , Estado Nutricional , Pobreza , Factores Socioeconómicos , España/etnología , Factores de Tiempo
17.
Rev Med Chil ; 127(8): 903-10, 1999 Aug.
Artículo en Español | MEDLINE | ID: mdl-10752250

RESUMEN

BACKGROUND: The few studies in Chile assessing the nutritional status of indigenous children show a high prevalence of stunting, excess weight and feeding problems. AIM: To compare anthropometric indices in children from indigenous and non indigenous ancestry. SUBJECTS AND METHODS: School children aged 6 to 8 years old, living in locations with three clear cut levels of social vulnerability were studied. Children were considered indigenous if their last names, as well as those of their parents were of Mapuche origin. Non indigenous were those whose last names were of Spanish origin. RESULTS: Four hundred and fifty indigenous and 684 non indigenous children were studied. Indigenous children from high vulnerability communities were approximately 0.5 z score shorter than those of non indigenous origin. Heights of indigenous and non indigenous children were similar in communities with intermediate and low social vulnerability. The proportion of the lower segment followed the same trend. Weight/height ratios were higher among indigenous children in the three vulnerability levels. Among indigenous children coming from areas of low vulnerability arm circumference was 1 cm broader than that of their non indigenous counterparts. CONCLUSIONS: Stunting is prevalent among school children from areas of high socioeconomic vulnerability, mainly rural, and independent from ethnicity. Among indigenous school children overweight and a broader arm circumference are frequent. These results urgently call for located and specific nutrition interventions.


Asunto(s)
Trastornos del Crecimiento/etnología , Indígenas Sudamericanos , Estado Nutricional , Análisis de Varianza , Niño , Chile/etnología , Humanos , Condiciones Sociales
18.
Arch Latinoam Nutr ; 48(4): 281-6, 1998 Dec.
Artículo en Español | MEDLINE | ID: mdl-10347690

RESUMEN

This communication offers suggestions for programs and policies in relation to stunting within the infant population. The proposal is based on current social strategies and the results of research carried out on Chilean school children. These results indicate that height deficit is concentrated in sectors of the population belonging to low socio-economic levels, and the risk factors are related to the small stature of their parents with a record of undernutrition, small size at birth and low per capita income. This deficit begins early, occurring mainly before the child's second birthday and as a consequence is reflected in below average performance at school of those children living in areas of social vulnerability. Suggestions offered take into account the orientation that should be considered for social policies, the selection of beneficiaries, program contents and management and problems that need to be overcome. Among these, the following issues are highlighted:--That the social welfare programs designed to combat stunting in the infant population should have, as a priority objective, the aim of benefiting sectors of the population most at need. It is vital to include in these programs: adequate pre-natal care of women with a high risk profile of giving birth to a child with intrauterine growth retardation; promotion of child growth; food supplementation and/or fortification, and improvement of physical fitness.--The government should play a leading role in the promotion and management of these programs, in the regulation of private sector involvement, as well as promoting local community participation.--Warnings are given about the inadequacies of present government social welfare policies related to infant nutrition, and the lack of research carried out into the effectiveness of current programs. In relation to future aims, we would like to see more emphasis put into the integration of international and regional intervention programs aimed at combating infant undernutrition. This would include sharing resources and collecting information related to the problem. Finally, all these actions should be aligned and focused on the principal aim; allowing children to reach their full growth potential.


Asunto(s)
Crecimiento , Planificación en Salud , Política Nutricional , Estatura , Estudios de Casos y Controles , Niño , Chile , Femenino , Humanos , Masculino , Factores de Riesgo
19.
Rev Med Chil ; 125(8): 863-8, 1997 Aug.
Artículo en Español | MEDLINE | ID: mdl-9567389

RESUMEN

BACKGROUND: Stunting is a prevalent problem in developing countries and may affect up to 50% of school age children. AIM: To search for a relationship between the short stature of school age children of opposing socioeconomic levels and that of their parents. SUBJECTS AND METHODS: One thousand, eight hundred and forty two children of low socioeconomic level and 2,770 children of high socioeconomic level were initially measured. Those with a z score for height below -1 were selected (251 of low socioeconomic level and 157 of high socioeconomic level) and the height of their parents was measured. RESULTS: Mothers and fathers of low socioeconomic level were 6.1 and 7.4 cm shorter than their counterparts of high socioeconomic level. The z score for height of low socioeconomic level children was significantly better than that of their parents and the relative risk for stunting was 2 when one of the parents had a short stature. Among children of high socioeconomic level, the relative risk of stunting was 4.8 and 11, when the mother or the father had a short stature, respectively. CONCLUSIONS: The better height adequacy of low socioeconomic level children, compared to their parents, suggests that the new generations are growing better than their ancestors. Among children of high socioeconomic level, whose growth potential is fully expressed, the parents height is a good predictor of stunting.


Asunto(s)
Estatura/fisiología , Crecimiento/fisiología , Padres , Estatura/genética , Niño , Femenino , Humanos , Masculino , Clase Social , Factores Socioeconómicos
20.
Arch Latinoam Nutr ; 47(4): 299-304, 1997 Dec.
Artículo en Español | MEDLINE | ID: mdl-9673688

RESUMEN

Governments in Latin American countries invest large amounts of resources in school feeding programmes, part of educational and social strategies to reach highly vulnerable group within the respective societies. We analysed the criteria used in selecting the beneficiaries of these programmes, the food distributed, management structures and lessons that have been learned from these processes. Differences found among development strategies in each country were also considered. At present, these strategies are centred on the efficient use of resources, focusing interventions on the neediest groups, and leaving aside the idea of universal benefits. In general, countries provide most types of food, such as breakfast lunch, snacks or just a glass of milk, free of charge. Recipients receive up to 1.000 calories and 30 g of selected protein per day. About execution; Latin American States have generally abandoned the integral management of these programmes, a former characteristic that included the purchasing of or production, reparation and delivery of specific food stuffs. Instead, the respective States have only maintained the organisational functions of planning and control of priority actions whilst the private sector has progressively taken an active part in developing strategies. Community participation is restricted to a minimum. We expect that this paper will be taken into consideration by those who bear the responsibility of formulating, executing and evaluating nutritional interventions directed at schoolchildren in selected Latin American regions.


Asunto(s)
Fenómenos Fisiológicos Nutricionales Infantiles , Servicios de Alimentación , Política Nutricional , Instituciones Académicas , Estudiantes , Niño , Humanos , América Latina , Evaluación de Programas y Proyectos de Salud , Servicios de Salud Escolar
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