RESUMEN
We present the case of a 29-year-old woman with the rare combination of lupus anticoagulant and bilateral optic disc edema. The linked etiopathologic problems are discussed to provide a proper clinical and ophthalmologic definition.
Asunto(s)
Inhibidor de Coagulación del Lupus/sangre , Papiledema/sangre , Corticoesteroides/uso terapéutico , Adulto , Enfermedades Autoinmunes/sangre , Femenino , Angiografía con Fluoresceína , Fondo de Ojo , Humanos , Papiledema/tratamiento farmacológico , Agudeza Visual , Campos VisualesRESUMEN
We report on 2 cases of granular dystrophy (Groenouw type I). We studied the nature and the ultrastructure of the typical stromal deposits by means of histochemical methods and of electron-microscopic examination. These deposits did not stain with Alcian blue, periodic acid-Schiff, Mallory, van Gieson, von Kossa or Congo red so that they are not constituted of proteoglycans, collagen, calcium or amyloid. They probably contain a proteic material. At the electron-microscopic level we observed electron-dense material which was made up of filaments immersed into an amorphous matrix.
