[The role of determining the level of middle molecules in patients in the diagnosis and treatment of suppurative-inflammatory complications after operations on the liver and pancreas]. / Rol' opredeleniia urovnia molekul srednei massy u bol'nykh v diagnostike i lechenii gnoino-vospalitel'nykh oslozhnenii posle operatsii na pecheni i podzheludochnoi zheleze.

Investigations of the level of medium-mass molecules were performed in blood plasma of 52 patients in dynamics after different operations on the liver and pancreas. Significant elevation of the level of medium-mass molecules was noted in patients with pyo-inflammatory complications. The inverse relationship between the level of medium-mass molecules and the prognostic coefficient value (the ratio of the general plasma protein to the general protein of wound discharge) was revealed. The indicators of the prognostic coefficient value decreased when the level of the medium-size molecules elevated against the background of purulent complications. These data allowed to estimate the severity of purulent complications and degree of intoxication which helped to determine the correct method of treatment of patients and to timely detect pyo-inflammatory complications.

[Effectiveness of drainage of the abdominal cavity after surgery of the liver and pancreas]. / Kontrol' éffektivnosti drenirovaniia briushnoi polosti posle operatsii pecheni i podzheludochnoi zheleze.

With the aim to control the effectiveness of drainage of the abdominal cavity after operations on the liver and pancreas in 28 patients, a value of the prognostic coefficient (PC) of the course of wound process (ratio of total protein level in the blood plasma of the patients to its content in wound discharge), content of middle molecular mass peptides in the blood, pH were measured in dynamics, qualitative reaction to gamma-globulins of the wound discharge was performed. The study of these indices in combination with clinical data permits to judge more fully about the effectiveness of the abdominal cavity drainage, to prognosticate purulent complications and to take in time measures for their prevention.