1.
Zh Vopr Neirokhir Im N N Burdenko
; 85(4): 111-117, 2021.
Artículo
en Ruso
| MEDLINE
| ID: mdl-34463458
RESUMEN
Cushing's disease is a severe neuroendocrine disorder caused by chronic hypersecretion of ACTH by pituitary adenoma (corticotropinoma). Surgical resection is a gold standard for this disease resulting stable remission in about 65-95% of cases. Despite benign nature of corticotropinoma, recurrence rate is still higher (25-35%) even in specialized neurosurgical centers. Modifications in surgical strategy can prolong recurrence-free period.