RESUMEN
Traumatic neuromas are tumors resulting from hyperplasia of axons and nerve sheath cells after section or injury to the nervous tissue. We present a case of this tumor, confirmed by anatomopathological examination, in a male patient with history of circumcision. Knowledge of this entity is very important in achieving the differential diagnosis with other lesions that affect the genital area such as condyloma acuminata, bowenoid papulosis, lichen nitidus, sebaceous gland hyperplasia, achrochordon and pearly penile papules.
Asunto(s)
Circuncisión Masculina/efectos adversos , Neuroma/etiología , Neoplasias del Pene/etiología , Diagnóstico Diferencial , Humanos , Masculino , Neuroma/patología , Neoplasias del Pene/patología , Pene/lesiones , Pene/patología , Adulto JovenRESUMEN
Abstract Traumatic neuromas are tumors resulting from hyperplasia of axons and nerve sheath cells after section or injury to the nervous tissue1. We present a case of this tumor, confirmed by anatomopathological examination, in a male patient with history of circumcision. Knowledge of this entity is very important in achieving the differential diagnosis with other lesions that affect the genital area such as condyloma acuminata, bowenoid papulosis, lichen nitidus, sebaceous gland hyperplasia, achrochordon and pearly penile papules.
Asunto(s)
Humanos , Masculino , Adulto Joven , Circuncisión Masculina/efectos adversos , Neuroma/etiología , Neoplasias del Pene/etiología , Diagnóstico Diferencial , Neuroma/patología , Neoplasias del Pene/patología , Pene/lesiones , Pene/patologíaRESUMEN
Pityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder. Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of several doubts regarding its etiology and also because of its relative rarity, making randomized studies difficult to perform. Some factors suggest that the metabolism of vitamin A is involved in pathogenesis. We report a case of Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which presented rapid and complete response after thyroid hormone replacement, without any association with other systemic treatment. In literature there are only three other reports of significant improvement of the lesions after hormonal correction. Deficiency of thyroid hormone inhibits the conversion of carotene into vitamin A, which would be responsible for the occurrence of Pityriasis Rubra Pilaris in this patient.
Asunto(s)
Hipotiroidismo/complicaciones , Pitiriasis Rubra Pilaris/etiología , Deficiencia de Vitamina A/complicaciones , Adulto , Terapia de Reemplazo de Hormonas , Humanos , Hipotiroidismo/tratamiento farmacológico , Masculino , Pitiriasis Rubra Pilaris/tratamiento farmacológico , Hormonas Tiroideas/uso terapéutico , Tiroxina/uso terapéutico , Resultado del Tratamiento , Vitamina A/uso terapéuticoRESUMEN
Pityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder. Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of several doubts regarding its etiology and also because of its relative rarity, making randomized studies difficult to perform. Some factors suggest that the metabolism of vitamin A is involved in pathogenesis. We report a case of Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which presented rapid and complete response after thyroid hormone replacement, without any association with other systemic treatment. In literature there are only three other reports of significant improvement of the lesions after hormonal correction. Deficiency of thyroid hormone inhibits the conversion of carotene into vitamin A, which would be responsible for the occurrence of Pityriasis Rubra Pilaris in this patient.
