RESUMEN
Introduction: Health-related quality of life (HRQoL) has emerged as an important outcome measure inpatients with CKD. The lack of prospective studies on HRQoL and its relation with hyperphosphatemia control measures among pre-dialysis patients necessitated the need for this study. Methods: This is a prospective, randomized, controlled, open-labelled studythat was conducted for one year on 120 CKD stages III and IV patients divided equally into three groups: Group 1, in which patients under went dietary phosphorus modification; Group 2, in which they were administered calcium-based phosphate binders; and Group 3, in which they were administered non-calcium-based phosphate binders. Patients were assessed for HRQoL, fibroblast growth factor 23 (FGF 23), intact parathyroid hormone (iPTH), phosphorus, and nutritional status, and dietary phosphorus control strategies at 0, 6, and 12 months. HRQoL was measured by using the 36-item Short Form Survey (SF-36) that included a physical component score (PCS) and mental component score (MCS). The scores is ranging from 0 to 100. Higher scores indicate better health status. Usingthe two-wayand one-way repeated measure ANOVA, we analyzed equality of group means, time intervals, and interactions. Results: At baseline, the mean PCS and MCS were equal in three groups. PCS improved significantly (P < 0.00) from baseline to one year in all the three groups: ingroup 1, the PCS score was 66.5 ± 13.5to 75.1 ± 9.76; in group 2, it was 68.9 ± 11.80 to 77.2 ± 7.50; and in group 3, it was 66.2 ± 12.16 to 73.8 ± 9.27. Initially, MCS declined substantially on the sixth month but recovered afterone year. Multiple regression analysis in 13 associated parameters yielded R2 of 13.7% and 18.1% in PCS and MCS, respectively, indicating little contribution of various parameters. Conclusion: There has been a significant positive change in PCSs in three hyperphosphatemia management groups over a period of 12 months. Among the three study groups, the incremental changes in PCS and MCS scores were insignificant.
RESUMEN
Introduction Tooth loss significantly impacts individuals' functional capabilities and quality of life. Fixed partial dentures have been a reliable treatment method for tooth replacement, with their fabrication often involving waxes. Waxes play a crucial role in creating a wax pattern in dental restoration; in particular, inlay waxes play a role in the shape, size, and contour of the restorations. However, these waxes have inherent disadvantages, including a high thermal expansion coefficient and propensity to warp or distort over time. This study aimed to compare wax patterns derived from two heat sources, an electric heat source and a conventional flame, to enhance their marginal accuracy and dimensional stability. Methods This study used an abutment resembling a prepared maxillary right central incisor designed via computer-aided design software and milled from zirconia. Inlay wax was melted using either an electrically heated spatula or a conventional flame, poured into a metal sleeve or a cuboidal mold, and allowed to cool to room temperature. The wax patterns were stored at room temperature for one hour and 24 hours. Subsequently, linear and volumetric measurements were taken to assess the shrinkage of the wax patterns. Results Patterns fabricated using the electric heat source showed less shrinkage at both time points for linear shrinkage and at one hour for volumetric shrinkage than those made using the conventional flame. However, by the 24th hour, patterns made with the electric heat source showed more volumetric shrinkage than those made with the conventional heat source. Significant shrinkage was observed between one hour and 24 hours for both heat sources, suggesting that wax patterns should be invested immediately after fabrication for maximum precision. Conclusions The results suggest that electric heating may be a viable alternative to conventional flame for minimizing discrepancies in wax patterns, particularly in the initial stages of wax pattern fabrication. However, prolonged use may lead to greater volumetric shrinkage with electric heating. These findings point to the potential of electric heating as an alternative to conventional flame in dental restorations, although further research is needed to validate and expand upon these findings.
