Phenolic Composition and Antioxidant Activity of Alchemilla Species.

The genus Alchemilla, belonging to the Rosaceae family, is a rich source of interesting secondary metabolites, including mainly flavonoids, tannins, and phenolic acids, which display a variety of biological activities, such as anti-inflammatory, antimicrobial, and antioxidant. Alchemilla species are used in traditional medicine for treatment of acute diarrhea, wounds, dysmenorrhea, and menorrhagia. In this review, we focus on the phenolic compound composition and antioxidative activity of Alchemilla species. We can assume that phytomedicine and natural products chemistry are of significant importance due to the fact that extract combinations with various bioactive compounds possess the activity to protect the human body rather than disturb damaging factors.

Cervical Myofascial Pain Is Associated with an Imbalance of Masticatory Muscle Activity.

This study aimed to assess the relationship between the occurrence of cervical myofascial pain with active myofascial trigger points (MTrPs) within the upper trapezius muscle and the electromyographic asymmetry index (AsI) of masticatory muscles: temporalis anterior (TA), superficial part of the masseter muscle (MM), and anterior belly of the digastric muscle (DA). The study group comprised 100 subjects (80 women and 20 men) aged 18 to 30 years (mean 23 ± 2.6 years) reporting pain in the neck muscles, diagnosed with myofascial pain with active MTrPs only within the upper trapezius muscle. The control group comprised 60 healthy, pain-free subjects (42 women and 18 men) aged 20 to 30 years (mean 22.8 ± 2.6 years) without MTrPs in the upper trapezius muscle. The palpation measurement, based on the diagnostic criteria of Travell and Simons, was used to diagnose active MTrPs. The masticatory muscle activity was recorded using an 8-channel device for surface electromyography-BioEMG IIITM. Significant differences in electromyographic patterns between the group with MTrPs in the right side of upper trapezius muscle and the control group were observed within resting activity for the AsI TA (MTrPs: 8.64 vs. controls: -3.22; p = 0.001) and AsI MM (MTrPs: 7.05 vs. controls: -2.09; p = 0.018). Controls presented different electromyographic patterns during maximum voluntary clenching with cotton rolls between teeth within masseter muscle compared to the MTrPs group (MTrPs: 9.27 vs. controls: -0.43 vs. p = 0.041). Participants with MTrPs in the left side of upper trapezius muscle presented predomination of left-sided electromyographic patterns at rest within temporalis anterior in comparison to controls (MTrPs: -19.22 vs. controls: -3.22; p = 0.001). MTrPs within the trapezius muscle may be related to asymmetry within the masticatory muscle activity, suggesting that the presence of myofascial pain within the cervical muscles plays a role in the imbalance of the stomatognathic system. A unilateral active MTrPs within the trapezius muscle may increase the sEMG activity on the same side of the temporalis anterior and masseter muscles.

[Correlation between generalized joint laxity and symptoms of temporomandibular disorders]. / Zwiazek miedzy wystepowaniem uogólnionej wiotkosci stawowej oraz zaburzen czynnosciowych ukladu ruchowego narzadu zucia.

UNLABELLED: Generalized joint hypermobility (GJH) is an increase of joints mobility over accepted norms. Many authors include GJH to etiologic factors of temporomandibular disorders (TMD). AIM: The aim of the study was to verify if there is an association between GJH and TMD. MATERIAL AND METHODS: Study was performed on 126 subjects (95 females and 31 males) aged 12-46 years. In order to find signs and symptoms of TMD Polish version of RDC/TMD questionnaire was used. GJH was assessed using Beighton's scale. Using r-Pearson's correlation an association between GHJ and TMD signs and symptoms was verified. RESULTS: No statistically significant association between TMD sings and symptoms and GJH was found. CONCLUSIONS: Presence of GJH is not associated with TMD signs and symptoms (in group of young adults).

Association between estrogen levels and temporomandibular disorders: a systematic literature review.

INTRODUCTION: To evaluate whether the hypothesis that estrogen levels are associated with temporomandibular disorders (TMD) in humans can be confirmed or contradicted by available literature. MATERIAL AND METHODS: A systematic review based on the content of PubMed, Scopus, and Cochrane Library databases was performed. Studies were identified using a combination of key words 'temporomandibular disorder' and 'estrogen'. Nine studies were included into our review. RESULTS: The relationship between estrogen levels and TMD was found in seven out of nine reviewed papers. Results from two papers suggest that a high estrogen level is associated with an increased prevalence of TMD. Five additional papers found a relationship between a low estrogen level and an increase in TMD pain. In considering the value of evidence and inconsistencies of results in the reviewed publications, we state that there is weak evidence to support the hypothesis that estrogen levels are associated with TMD. CONCLUSIONS: Results of reviewed studies were divergent and sometimes contradictory. One possible explanation is that estrogen influences TMD pain processing differently than temporomandibular joints (TMJ) structures, as shown in many animal studies. Estrogen may influence TMD pain processing differently than TMJ structures. We suggest consideration of the dual action of estrogen when planning future studies on its association with TMD.

Prosthetic rehabilitation of edentulous patients with cleft palate.

In this work a description of prosthetic treatment of the edentulous patient with cleft palate was showed. Although positive results of surgical treatment diminish the number of these patients, more than once a dentist has to treat effectively patients in their fifties, sixties and seventies whose cleft palate was not treated with modern methods. Authors describe prosthetic solution which enables removing part of acryl from prosthesis and making air chambers. Diminishing of obturator prosthesis mass increases stabilization and retention and contributes to easier adaptation of prosthetic restoration.

Diagnostic abilities of three-dimensional electronic axiography on the basis of ARCUSdigma device.

The ARCUSdigma is an electronic facebow enabling presentation and graphic analysis of mandibular movements on the computer screen. A kinematic hinge axis of the mandible can be determined using this device. The paper presents the diagnostic potential of the ARCUSdigma in relation to programming an articulator according to individual parameters of mandibular movements of the patient and its application in the diagnosis of temporo-mandibular joints.

Removable dentures and relations between their construction, adaptation and functionality role and influence on dysgeusia.

A large foreign body inserted into oral cavity, e.g. complete denture, both lower and upper, might cause a temporary or constant dysarthia and dysgeusia. These might be reduced and even completely eliminated by proper dentures construction. Problems with normal articulation might result from construction faults, e.g. too thick denture base, incorrect denture base modelling, wrong teeth placement, lowering or excessive height occlusion. The hypogeusia has been repeatedly observed as the symptom in the course of the complete denture adaptation stage, as well as might keep further. The main role in the mechanism of occurrence of hypogeusia has the limitation of the lingual flexibility, especially of its tip, throughout the use of the complete denture. It provokes difficulties with the accurate course of its physiological activity as well as makes impossible the balancing with the tongue of the cryaesthesia, heath sensibility and tactile sense, which are blocked on the palate.

Iatrogenic pain dysfunction syndrome of the masticatory system--case study.

A female patient, age 71, came to The Department of Prosthetic Dentistry University School of Medicine in Lublin with pain dysfunction syndrome after treatment by extensive prosthesis of upper and lower dental arches. After examination many abnormalities of prosthetic restorations were ascertained. After 21 months of repositioning occlusal splint treatment the symptoms of pain dysfunction were gone, which permitted final prosthetic restoration. This case proves that using repositioning occlusal splint should be the first choice procedure in the treatment of iatrogenic pain after prosthetic treatment.