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Bioorg Med Chem Lett
; 12(2): 261-4, 2002 Jan 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-11755367
RESUMEN
Compounds combining NK(1) antagonism and serotonin reuptake inhibition are described, and potentially represent a new generation of antidepressants. Compound 24 displays good affinities for both the NK(1) receptor and the serotonin reuptake site (32 and 25 nM, respectively).