RESUMEN
To study the macular thickness and peripapillary nerve fibre layer thickness in children with anisometropic amblyopia, a prospective non-randomised case series study was undertaken among 39 children (25 boys and 14 girls) aged between 5 and 16 years. This study was carried out between January 2010 and April 2011. The peripapillary retinal nerve fibre layer (RNFL) thickness and macular layer thickness was measured using optical coherence tomography (OCT), the RNFL thickness and the macular layer thickness of the amblyopic eye was assessed and compared to the normal eye of the same subject. It was found that macular layer thickness in the amblyopic eye was greater than that of the macular thickness in the normal eye. The mean macular layer thickness in the amblyopic eyes was 229.589 microm with a standard deviation of -+/- 31.9149 microm. The mean macular layer thickness in the normal eyes of these children was 206.8717 microm with a standard deviation of +/- 28.490 microm, the p-value was 0.00141 which is much lesser than 0.005 and hence is strongly statistically significant. However the mean RNFL thickness in the amblyopic eye was 104.454 microm with a standard deviation of +/- 22.244 microm. The mean RNFL thickness of the normal eye was 108.2746 microm with a SD of +/- 19.370 microm. The p-value in this case being 0.4246 which is statistically insignificant. It is conducted that macular layer thickness is raised in the amblyopic eye of children with anisometropic amblyopia though the RNFL thickness is not.
Asunto(s)
Ambliopía/patología , Mácula Lútea/patología , Fibras Nerviosas/patología , Neuronas Retinianas/patología , Adolescente , Estudios de Casos y Controles , Niño , Preescolar , Femenino , Humanos , India , Masculino , Estudios Prospectivos , Tomografía de Coherencia ÓpticaRESUMEN
Diabetes is a worldwide medical problem and is a significant cause of morbidity and mortality. It has considerable impact on both the patient and the society because it typically affects individuals in their most productive years. It is also one of the leading causes of blindness and visual impairment. A person with diabetes has 25 times the risk of blindness compared to a non-diabetic. This article reviews the variety of ways in which the eye and its adnexa can be involved in diabetes mellitus.
