RESUMEN
Partial thrombosis of the corpus cavernosum, also known as partial priapism is a rare condition. The condition is known to be unilateral, and its aetiology is not well known. Usually, symptoms are pain and perineal mass and Magnetic Resonance is needed to confirm the diagnosis. In most cases the treatment is conservative with anticoagulation therapy. We present a case of partial thrombosis of the corpus cavernosum with a Factor V Leyden mutation.
Asunto(s)
Factor V/genética , Priapismo/diagnóstico por imagen , Trombosis/diagnóstico por imagen , Anticoagulantes/uso terapéutico , Aspirina/uso terapéutico , Quimioterapia Combinada , Enoxaparina/uso terapéutico , Humanos , Imagen por Resonancia Magnética , Masculino , Priapismo/tratamiento farmacológico , Priapismo/genética , Trombosis/tratamiento farmacológico , Trombosis/genética , Resultado del Tratamiento , Ultrasonografía , Adulto JovenRESUMEN
We analysed serum uric acid concentrations in a group of healthy male and female volunteers in Córdoba (Spain) possessing varying nutritional habits, in order to correlate them with their usual alcohol intake as measured according to a protocolized, blind dietary questionnaire. There was no significant correlation between the serum uric acid and the amount of alcohol regularly drunk by either male or female individuals. These results suggest that a moderate alcohol intake has no effect on uricaemia in healthy individuals.
Asunto(s)
Consumo de Bebidas Alcohólicas/sangre , Ácido Úrico/sangre , Adulto , Relación Dosis-Respuesta a Droga , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valores de Referencia , Factores SexualesRESUMEN
We studied the renal urate excretory function in two groups of hyperuricaemic male patients composed of individuals with associated hyperlipidemia and hyperuricaemic-normolipidemic individuals, respectively. Both the hyperlipidemia and the hyperuricaemia were primary inasmuch as none of the patients studied was obese or had an above-normal alcohol intake or blood hypertension. The results obtained show that hyperuricaemic-hyperlipidemic patients have higher serum levels of uric acid and poorer urate excretion as reflected in smaller clearance and fractioned excretion of the metabolite than hyperuricaemic-normolipidemic patients. This, in turn, suggests the occurrence of differences in the extent of the urate handling anomalies between the two groups of patients.
Asunto(s)
Hiperlipidemias/metabolismo , Riñón/metabolismo , Ácido Úrico/sangre , Ácido Úrico/metabolismo , Adulto , Anciano , Humanos , Hiperlipidemias/complicaciones , Hiperlipidemias/fisiopatología , Riñón/fisiopatología , Pruebas de Función Renal , Lipoproteínas/sangre , Lipoproteínas/clasificación , Masculino , Persona de Mediana EdadRESUMEN
We carried out a study of 43 male asymptomatic subjects with high levels of uric acid but showing no signs of arterial hypertension, obesity or alcohol abuse. Initially, we investigated cholesterol levels, triglycerides in blood serum and the very low density lipoprotein fraction. The results showed asymptomatic hyperuricemia, frequently associated with mixed hyperlipidemia or hypertriglyceridemia. In our cases, however, the association was not connected to exogenous factors such as obesity or alcohol consumption. We also found the very low density lipoprotein fraction to be anomalous compared to the control group, which suggests that the metabolism of this lipoprotein is altered by the aforesaid association.